NO20021382L - Fremgangsmåter og mikroorganismer for fremstilling av panto- forbindelser - Google Patents
Fremgangsmåter og mikroorganismer for fremstilling av panto- forbindelserInfo
- Publication number
- NO20021382L NO20021382L NO20021382A NO20021382A NO20021382L NO 20021382 L NO20021382 L NO 20021382L NO 20021382 A NO20021382 A NO 20021382A NO 20021382 A NO20021382 A NO 20021382A NO 20021382 L NO20021382 L NO 20021382L
- Authority
- NO
- Norway
- Prior art keywords
- panto
- microorganisms
- compounds
- preparation
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
- C12N9/1014—Hydroxymethyl-, formyl-transferases (2.1.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40049499A | 1999-09-21 | 1999-09-21 | |
| US21007200P | 2000-06-07 | 2000-06-07 | |
| US22183600P | 2000-07-28 | 2000-07-28 | |
| US22786000P | 2000-08-24 | 2000-08-24 | |
| PCT/US2000/025993 WO2001021772A2 (en) | 1999-09-21 | 2000-09-21 | Methods and microorganisms for production of panto-compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20021382D0 NO20021382D0 (no) | 2002-03-20 |
| NO20021382L true NO20021382L (no) | 2002-05-16 |
Family
ID=27498789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20021382A NO20021382L (no) | 1999-09-21 | 2002-03-20 | Fremgangsmåter og mikroorganismer for fremstilling av panto- forbindelser |
Country Status (16)
| Country | Link |
|---|---|
| EP (2) | EP2163629B1 (no) |
| JP (1) | JP5392957B2 (no) |
| KR (1) | KR20020092912A (no) |
| CN (1) | CN1420931A (no) |
| AU (1) | AU7708700A (no) |
| BR (1) | BRPI0014115B8 (no) |
| CA (1) | CA2385497A1 (no) |
| CZ (1) | CZ20021013A3 (no) |
| HU (1) | HU230509B1 (no) |
| IL (1) | IL148786A0 (no) |
| MX (1) | MXPA02003017A (no) |
| NO (1) | NO20021382L (no) |
| PL (1) | PL356566A1 (no) |
| SK (1) | SK5222002A3 (no) |
| TR (1) | TR200200751T2 (no) |
| WO (1) | WO2001021772A2 (no) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6830898B2 (en) | 2000-08-24 | 2004-12-14 | Omnigene Bioproducts, Inc. | Microorganisms and assays for the identification of antibiotics |
| DE10101501A1 (de) * | 2001-01-12 | 2002-08-01 | Forschungszentrum Juelich Gmbh | Verfahren zur fermentativen Herstellung von Pantothensäure |
| RU2003125653A (ru) * | 2001-01-19 | 2005-03-10 | БАСФ Акциенгезельшафт (DE) | Способы улучшенного получения пантотената |
| CN100529068C (zh) * | 2001-01-19 | 2009-08-19 | 巴斯福股份公司 | 用于提高泛酸产量的微生物和方法 |
| DE10108225A1 (de) * | 2001-02-21 | 2002-10-10 | Basf Ag | Verfahren zur Herstellung von D-Pantothensäure und/oder deren Salze als Zusatz zu Tierfuttermitteln |
| DE10108223A1 (de) | 2001-02-21 | 2002-10-10 | Basf Ag | Verfahren zur Herstellung von D-Pantothensäure und/oder deren Salze als Zusatz zu Tierfuttermitteln |
| BR0207473A (pt) | 2001-02-21 | 2004-04-06 | Basf Ag | Processo para preparar ácido d-pantotênico e/ou seus sais, e, composição para uso como aditivo de alimento para animal e/ou suplemento de alimento para animal |
| IL157495A0 (en) * | 2001-02-21 | 2004-03-28 | Basf Ag | Method for the production of d-panthothenic acid and/or salts thereof as adjunct for animal feedstuffs |
| EP1247868A3 (de) * | 2001-04-03 | 2002-10-30 | Degussa AG | Verfahren zur fermentativen Herstellung von D-Pantothensäure und/oder deren Salzen |
| WO2003004672A1 (en) * | 2001-07-03 | 2003-01-16 | Degussa Ag | Process for the fermentative preparation of d-pantothenic acid and/or salts thereof |
| WO2003004673A1 (en) * | 2001-07-03 | 2003-01-16 | Degussa Ag | Process for the fermentative preparation of d-pantothenic acid and/or salts thereof |
| DE10132178A1 (de) | 2001-07-03 | 2003-01-23 | Degussa | Verfahren zur fermantativen Herstellung von D-Pantothensäure und/oder deren Salzen |
| EP1672073A1 (en) * | 2001-07-07 | 2006-06-21 | Degussa AG | Process for the preparation of D-pantothenic acid and/or salts thereof |
| EP1404840A2 (en) * | 2001-07-07 | 2004-04-07 | Degussa AG | Process for the preparation of d-pantothenic acid and/or salts thereof |
| EP1575881B1 (en) | 2002-01-18 | 2009-05-27 | Novozymes A/S | Alanine 2,3- aminomutase |
| EP1520030B1 (en) * | 2002-07-03 | 2011-10-26 | Basf Se | Microorganisms and processes for enhanced production of pantothenate |
| CN1788089A (zh) | 2002-07-03 | 2006-06-14 | 巴斯福股份公司 | 用于提高泛酸产量的微生物和方法 |
| CN1809631B (zh) * | 2003-06-18 | 2010-05-26 | 帝斯曼知识产权资产管理有限公司 | 用不能形成芽孢的微生物来生产泛酸盐/酯的方法 |
| JPWO2006104124A1 (ja) * | 2005-03-29 | 2008-09-11 | 株式会社カネカ | 新規パントテン酸キナーゼ遺伝子及びその利用方法 |
| US8273558B2 (en) | 2005-10-26 | 2012-09-25 | Butamax(Tm) Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US9303225B2 (en) | 2005-10-26 | 2016-04-05 | Butamax Advanced Biofuels Llc | Method for the production of isobutanol by recombinant yeast |
| RU2394913C2 (ru) | 2005-10-26 | 2010-07-20 | Е.И.Дюпон Де Немур Энд Компани | Ферментативное получение четырехуглеродных спиртов |
| CN101448950B (zh) | 2006-05-16 | 2014-02-12 | 帝斯曼知识产权资产管理有限公司 | 用于生产泛醇的工艺 |
| EP1918383A1 (en) * | 2006-11-02 | 2008-05-07 | DSMIP Assets B.V. | Semi-continuous fermentation process for pantothenate production |
| KR20090117739A (ko) | 2007-02-09 | 2009-11-12 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 재조합 미생물을 이용한 생물연료의 생산 |
| US8293504B2 (en) | 2007-07-06 | 2012-10-23 | Basf Se | Method for the production of an aqueous glucose solution |
| NO2265709T3 (no) * | 2008-03-27 | 2018-04-07 | ||
| EP2157174A1 (en) | 2008-08-12 | 2010-02-24 | DSM IP Assets B.V. | Increased production of pantothenate (vitamin B5) |
| US9416364B2 (en) * | 2011-02-07 | 2016-08-16 | William Marsh Rice University | Reverse beta oxidation pathway |
| US8765426B2 (en) * | 2011-04-07 | 2014-07-01 | E I Du Pont De Nemours And Company | Pantothenic acid biosynthesis in zymomonas |
| WO2012175575A2 (en) | 2011-06-21 | 2012-12-27 | Dsm Ip Assets B.V. | Increased vitamin b5 production |
| WO2012175574A1 (en) | 2011-06-21 | 2012-12-27 | Dsm Ip Assets B.V. | Increased pantothenate (vitamin b5) production |
| WO2014087184A1 (en) * | 2012-12-03 | 2014-06-12 | Metabolic Explorer | Neopentyl glycol fermentative production by a recombinant microorganism |
| US9896464B2 (en) | 2013-10-25 | 2018-02-20 | Retrophin, Inc. | Pantothenate derivatives for the treatment of neurological disorders |
| CN104593398B (zh) * | 2013-11-01 | 2017-06-06 | 中国科学院微生物研究所 | 一种高L‑天冬氨酸α羧化酶活性的工程菌及其在生产β‑丙氨酸中的应用 |
| CN105368758B (zh) * | 2015-03-16 | 2018-06-19 | 鲁东大学 | 一株高产天冬氨酸脱羧酶的菌株及用于生产丙氨酸的方法 |
| CN104789564B (zh) * | 2015-03-31 | 2018-04-27 | 中国农业科学院生物技术研究所 | 一种启动子和重组表达载体及其用途和表达外源蛋白的方法 |
| AU2016366977A1 (en) | 2015-12-08 | 2018-07-12 | Retrophin, Inc. | Cyclic phosphates and cyclic phosphoramidates for the treatment of neurologic disorders |
| JP2020530271A (ja) | 2017-06-30 | 2020-10-22 | ピーティーティー グローバル ケミカル パブリック カンパニー リミテッド | 安定化されたコピー数の機能性ｄｎａ配列を有する微生物及び関連方法 |
| CN108456701B (zh) * | 2018-03-23 | 2020-10-16 | 精晶药业股份有限公司 | 一种d-泛解酸内酯的制备方法 |
| EP3810786A4 (en) * | 2018-06-25 | 2022-06-08 | Lygos, Inc. | RECOMBINED HOST CELLS AND METHODS FOR PRODUCING ASPARTIC ACID AND BETA-ALANINE |
| US10889806B2 (en) | 2018-07-09 | 2021-01-12 | Codexis, Inc. | Engineered pantothenate kinase variant enzymes |
| EP4174185A4 (en) * | 2020-06-28 | 2024-05-22 | Mint Biotechnologies Co., Ltd. | PROCESS FOR THE PRODUCTION OF PANTOTHENIC ACID, PANTHENIC ACID AND PANTHENOL AND SALTS THEREOF |
| KR102389327B1 (ko) * | 2020-07-01 | 2022-04-20 | 씨제이제일제당 (주) | 3-메틸-2-옥소뷰타노에이트 하이드록시 메틸트랜스퍼라아제의 활성이 강화된 미생물, 및 이의 용도 |
| CN115109736B (zh) * | 2021-03-23 | 2024-05-07 | 中国科学院天津工业生物技术研究所 | 一种产泛解酸的微生物及其构建方法和应用 |
| WO2022219173A1 (en) | 2021-04-15 | 2022-10-20 | Dsm Ip Assets B.V. | Production of panthenol |
| EP4108654A1 (en) | 2021-06-23 | 2022-12-28 | DSM IP Assets B.V. | Production of panthenol |
| CN114085820B (zh) * | 2021-11-19 | 2023-10-20 | 万华化学集团股份有限公司 | 来源于Candida viswanathii的酮基泛解酸内酯还原酶 |
| CN114437988B (zh) * | 2022-02-28 | 2023-05-23 | 贵州医科大学 | 纤维素降解菌及菌剂、制备方法、应用和降解酒糟的方法 |
| CN115595314A (zh) * | 2022-03-07 | 2023-01-13 | 中国科学院微生物研究所（Cn） | 表达天冬氨酸脱氢酶的工程菌及发酵生产维生素b5的方法 |
| CN115595328A (zh) * | 2022-03-07 | 2023-01-13 | 中国科学院微生物研究所（Cn） | 天冬氨酸脱羧酶在发酵生产维生素b5中的应用 |
| WO2024110278A1 (en) | 2022-11-21 | 2024-05-30 | Dsm Ip Assets B.V. | Production of panthenol |
| EP4378923A1 (en) | 2022-12-01 | 2024-06-05 | DSM IP Assets B.V. | Production of panthenol |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5024943A (en) * | 1985-11-07 | 1991-06-18 | Gist-Brocades | Regulatory region cloning and analysis plasmid for bacillus |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| JP3710497B2 (ja) | 1992-09-25 | 2005-10-26 | ビーエーエスエフ アクチェンゲゼルシャフト | Ｄ−パント酸、ｄ−パントテン酸およびそれらの塩の製造法 |
| KR100421088B1 (ko) | 1995-09-13 | 2004-06-04 | 바스프 악티엔게젤샤프트 | 디-판토산및디-판토텐산또는그의염의생성방법 |
| US5834259A (en) * | 1996-10-28 | 1998-11-10 | Monsanto Company | Process and composition for preparing D-aspartic acid |
| DE19855313A1 (de) * | 1998-12-01 | 2000-06-08 | Degussa | Verfahren zur fermentativen Herstellung von D-Pantothensäure durch Verstärkung des panD-Gens in Mikroorganismen |
| DE19855312A1 (de) * | 1998-12-01 | 2000-06-08 | Degussa | Verfahren zur fermentativen Herstellung von D-Pantothensäure unter Verwendung coryneformer Bakterien |
-
2000
- 2000-09-21 PL PL00356566A patent/PL356566A1/xx not_active Application Discontinuation
- 2000-09-21 EP EP09179840.5A patent/EP2163629B1/en not_active Expired - Lifetime
- 2000-09-21 AU AU77087/00A patent/AU7708700A/en not_active Abandoned
- 2000-09-21 HU HU0202705A patent/HU230509B1/hu not_active IP Right Cessation
- 2000-09-21 CZ CZ20021013A patent/CZ20021013A3/cs unknown
- 2000-09-21 CA CA002385497A patent/CA2385497A1/en not_active Abandoned
- 2000-09-21 WO PCT/US2000/025993 patent/WO2001021772A2/en not_active Application Discontinuation
- 2000-09-21 EP EP00966799.9A patent/EP1214420B1/en not_active Expired - Lifetime
- 2000-09-21 JP JP2001525331A patent/JP5392957B2/ja not_active Expired - Fee Related
- 2000-09-21 MX MXPA02003017A patent/MXPA02003017A/es unknown
- 2000-09-21 CN CN00815771A patent/CN1420931A/zh active Pending
- 2000-09-21 TR TR2002/00751T patent/TR200200751T2/xx unknown
- 2000-09-21 IL IL14878600A patent/IL148786A0/xx unknown
- 2000-09-21 KR KR1020027003732A patent/KR20020092912A/ko not_active Application Discontinuation
- 2000-09-21 SK SK522-2002A patent/SK5222002A3/sk unknown
- 2000-09-21 BR BRPI0014115A patent/BRPI0014115B8/pt not_active IP Right Cessation
-
2002
- 2002-03-20 NO NO20021382A patent/NO20021382L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001021772A3 (en) | 2002-03-07 |
| BR0014115A (pt) | 2002-05-21 |
| BRPI0014115B1 (pt) | 2015-05-05 |
| EP2163629B1 (en) | 2017-03-08 |
| PL356566A1 (en) | 2004-06-28 |
| EP1214420A2 (en) | 2002-06-19 |
| AU7708700A (en) | 2001-04-24 |
| CA2385497A1 (en) | 2001-03-29 |
| WO2001021772A2 (en) | 2001-03-29 |
| TR200200751T2 (tr) | 2004-08-23 |
| WO2001021772A9 (en) | 2002-12-05 |
| SK5222002A3 (en) | 2003-03-04 |
| HUP0202705A3 (en) | 2011-02-28 |
| EP2163629A3 (en) | 2010-06-02 |
| JP5392957B2 (ja) | 2014-01-22 |
| IL148786A0 (en) | 2002-09-12 |
| MXPA02003017A (es) | 2004-09-06 |
| KR20020092912A (ko) | 2002-12-12 |
| HU230509B1 (hu) | 2016-09-28 |
| HUP0202705A2 (hu) | 2002-12-28 |
| JP2003527828A (ja) | 2003-09-24 |
| BRPI0014115B8 (pt) | 2021-05-25 |
| CN1420931A (zh) | 2003-05-28 |
| CZ20021013A3 (en) | 2002-12-11 |
| EP1214420B1 (en) | 2016-03-23 |
| NO20021382D0 (no) | 2002-03-20 |
| EP2163629A2 (en) | 2010-03-17 |
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