NO20003067D0 - Antipicornavirus-forbindelser og fremgangsmÕter for deres anvendelse og fremstilling - Google Patents
Antipicornavirus-forbindelser og fremgangsmÕter for deres anvendelse og fremstillingInfo
- Publication number
- NO20003067D0 NO20003067D0 NO20003067A NO20003067A NO20003067D0 NO 20003067 D0 NO20003067 D0 NO 20003067D0 NO 20003067 A NO20003067 A NO 20003067A NO 20003067 A NO20003067 A NO 20003067A NO 20003067 D0 NO20003067 D0 NO 20003067D0
- Authority
- NO
- Norway
- Prior art keywords
- antipicornavirus
- compounds
- preparation
- methods
- antipicornavirus compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Crystallography & Structural Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/991,739 US5962487A (en) | 1997-12-16 | 1997-12-16 | Antipicornaviral compounds and methods for their use and preparation |
| PCT/US1998/026583 WO1999031122A1 (en) | 1997-12-16 | 1998-12-15 | Antipicornaviral compounds and methods for their use and preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20003067D0 true NO20003067D0 (no) | 2000-06-15 |
| NO20003067L NO20003067L (no) | 2000-08-15 |
Family
ID=25537509
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20003067A NO20003067L (no) | 1997-12-16 | 2000-06-15 | Antipicornavirus-forbindelser og fremgangsmÕter for deres anvendelse og fremstilling |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5962487A (no) |
| EP (1) | EP1037905A1 (no) |
| JP (1) | JP2002508389A (no) |
| KR (1) | KR20010033236A (no) |
| AU (1) | AU762682B2 (no) |
| BR (1) | BR9813651A (no) |
| CA (1) | CA2312940A1 (no) |
| HU (1) | HUP0100149A3 (no) |
| IL (1) | IL136308A0 (no) |
| IS (1) | IS5510A (no) |
| NO (1) | NO20003067L (no) |
| NZ (1) | NZ505034A (no) |
| PL (1) | PL341435A1 (no) |
| WO (1) | WO1999031122A1 (no) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6214799B1 (en) * | 1996-05-14 | 2001-04-10 | Agouron Pharmaceuticals, Inc. | Antipicornaviral compounds and methods for their use and preparation |
| EP1329457B1 (en) * | 1998-04-30 | 2005-11-02 | Agouron Pharmaceuticals, Inc. | Antipicornaviral compounds, their preparation and use |
| ES2205760T3 (es) * | 1998-04-30 | 2004-05-01 | Agouron Pharmaceuticals, Inc. | Compuestos antipicornavirales, su preparacion y su utilizacion. |
| US6143079A (en) * | 1998-11-19 | 2000-11-07 | Asm America, Inc. | Compact process chamber for improved process uniformity |
| US6369226B1 (en) | 1999-06-21 | 2002-04-09 | Agouron Pharmaceuticals, Inc. | Substituted benzamide inhibitors of rhinovirus 3C protease |
| BR0012970A (pt) * | 1999-08-04 | 2002-04-30 | Agouron Pharma | Compostos e composições antipicornavirais, seus usos farmacêuticos e materiais para a sua sìntese |
| PE20010517A1 (es) * | 1999-08-24 | 2001-05-16 | Agouron Pharma | Las rutas sinteticas eficientes para la preparacion de los inhibidores de la proteasa del rinovirus y los intermedios claves |
| US6355807B1 (en) * | 1999-08-24 | 2002-03-12 | Agouron Pharmaceuticals, Inc. | Efficient synthetic routes for the preparation of rhinovirus protease inhibitors and key intermediates |
| US6774243B2 (en) | 1999-08-24 | 2004-08-10 | Agouron Pharmaceuticals, Inc. | Efficient synthetic routes for the preparation of rhinovirus protease inhibitors and key intermediates |
| PE20020157A1 (es) | 1999-12-03 | 2002-02-22 | Agouron Pharma | Compuestos derivados de piridona como inhibidores de proteasas de picornaviral 3c, composiciones, sus usos farmaceuticos y materiales para su sintesis |
| JP2003525294A (ja) * | 2000-02-29 | 2003-08-26 | ブリストル−マイヤーズ スクイブ ファーマ カンパニー | Ｃ型肝炎ウイルスｎｓ３プロテアーゼの阻害剤 |
| PE20011277A1 (es) | 2000-04-14 | 2002-01-07 | Agouron Pharma | Compuestos y composiciones antipicornavirales, sus usos farmaceuticos y los materiales para su sintesis |
| JP2004503533A (ja) * | 2000-06-14 | 2004-02-05 | アグロン・ファーマシュウティカルズ・インコーポレーテッド | 抗ピコルナウイルス化合物及び組成物、その医薬的使用、並びにその合成のための物質 |
| US6653295B2 (en) | 2000-12-13 | 2003-11-25 | Bristol-Myers Squibb Company | Inhibitors of hepatitis C virus NS3 protease |
| PL219737B1 (pl) * | 2002-03-22 | 2015-07-31 | Eisai R & D Man Co | Pochodne hemiasterliny, środek farmaceutyczny i zastosowanie pochodnych i zastosowanie hemiasterliny |
| US7064211B2 (en) | 2002-03-22 | 2006-06-20 | Eisai Co., Ltd. | Hemiasterlin derivatives and uses thereof |
| AU2003238304A1 (en) * | 2002-06-26 | 2004-01-19 | Bristol-Myers Squibb Company | Bicyclic pyrimidinones as coagulation cascade inhibitors |
| US20030125548A1 (en) * | 2002-09-13 | 2003-07-03 | Dorit Arad | Molecules derived from mechanism based drug design |
| CN1922137A (zh) * | 2003-12-31 | 2007-02-28 | 太景生物科技股份有限公司 | 蛋白酶抑制剂 |
| US7462594B2 (en) * | 2003-12-31 | 2008-12-09 | Taigen Biotechnology Co., Ltd. | Peptide-like compounds that inhibit coronaviral 3CL and flaviviridae viral proteases |
| DK2288615T3 (en) | 2008-05-21 | 2017-09-04 | Genesis Tech Ltd | SELECTIVE CASPASE INHIBITORS AND APPLICATIONS THEREOF |
| US9045524B2 (en) | 2009-05-21 | 2015-06-02 | Novagenesis Foundation | Selective caspase inhibitors and uses thereof |
| ES2665301T3 (es) | 2011-04-15 | 2018-04-25 | Genesis Technologies Limited | Inhibidores selectivos de cisteína proreasa y usos de los mismos |
| CA2850003C (en) | 2011-09-27 | 2020-01-07 | Kansas State University Research Foundation | Broad-spectrum antivirals against 3c or 3c-like proteases of picornavirus-like supercluster: picornaviruses, caliciviruses and coronaviruses |
| JP2013180983A (ja) * | 2012-03-01 | 2013-09-12 | Tokyo Univ Of Agriculture & Technology | Ｎ置換アミド化合物の製造方法 |
| CA2872147A1 (en) | 2012-05-02 | 2013-11-07 | Kansas State University Research Foundation | Macrocyclic and peptidomimetic compounds as broad-spectrum antivirals against 3c or 3c-like proteases of picornaviruses, caliciviruses and coronaviruses |
| US20230151034A1 (en) * | 2020-03-17 | 2023-05-18 | Cocrystal Pharma, Inc. | Peptidomimetic n5-methyl-n2-(nonanoyl-l-leucyl)-l-glutaminate derivatives, triazaspiro[4.14]nonadecane derivatives and similar compounds as inhibitors of norovirus and coronavirus replication |
| CN116648240A (zh) * | 2021-01-22 | 2023-08-25 | 中国人民解放军军事科学院军事医学研究院 | 一种环肽类病毒蛋白酶抑制剂，其制备方法，及其在抗病毒药物中的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0668870A1 (en) * | 1991-06-14 | 1995-08-30 | Chiron Corporation | Inhibitors of picornavirus proteases |
| US5514778A (en) * | 1993-07-01 | 1996-05-07 | Eli Lilly And Company | Anti-picornaviral agents |
| IL112759A0 (en) * | 1994-02-25 | 1995-05-26 | Khepri Pharmaceuticals Inc | Novel cysteine protease inhibitors |
| IT1269511B (it) * | 1994-05-17 | 1997-04-01 | Univ Degli Studi Milano | Derivati di acidi ammino-solfonici , loro impiego nella sintesi di pseudopeptidi e procedimento per la loro preparazione |
| CA2254343A1 (en) * | 1996-05-14 | 1997-11-20 | Agouron Pharmaceuticals, Inc. | Inhibitors of picornavirus 3c proteases and methods for their use and preparation |
-
1997
- 1997-12-16 US US08/991,739 patent/US5962487A/en not_active Expired - Fee Related
-
1998
- 1998-12-15 HU HU0100149A patent/HUP0100149A3/hu unknown
- 1998-12-15 AU AU18262/99A patent/AU762682B2/en not_active Ceased
- 1998-12-15 EP EP98963184A patent/EP1037905A1/en not_active Withdrawn
- 1998-12-15 BR BR9813651-8A patent/BR9813651A/pt not_active IP Right Cessation
- 1998-12-15 CA CA002312940A patent/CA2312940A1/en not_active Abandoned
- 1998-12-15 IL IL13630898A patent/IL136308A0/xx unknown
- 1998-12-15 PL PL98341435A patent/PL341435A1/xx unknown
- 1998-12-15 NZ NZ505034A patent/NZ505034A/en unknown
- 1998-12-15 JP JP2000539045A patent/JP2002508389A/ja not_active Withdrawn
- 1998-12-15 KR KR1020007006647A patent/KR20010033236A/ko not_active Application Discontinuation
- 1998-12-15 WO PCT/US1998/026583 patent/WO1999031122A1/en not_active Application Discontinuation
-
2000
- 2000-05-25 IS IS5510A patent/IS5510A/is unknown
- 2000-06-15 NO NO20003067A patent/NO20003067L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US5962487A (en) | 1999-10-05 |
| BR9813651A (pt) | 2000-10-03 |
| CA2312940A1 (en) | 1999-06-24 |
| PL341435A1 (en) | 2001-04-09 |
| JP2002508389A (ja) | 2002-03-19 |
| EP1037905A1 (en) | 2000-09-27 |
| AU762682B2 (en) | 2003-07-03 |
| HUP0100149A3 (en) | 2001-12-28 |
| KR20010033236A (ko) | 2001-04-25 |
| NO20003067L (no) | 2000-08-15 |
| HUP0100149A2 (hu) | 2001-06-28 |
| AU1826299A (en) | 1999-07-05 |
| NZ505034A (en) | 2003-07-25 |
| IL136308A0 (en) | 2001-05-20 |
| WO1999031122A1 (en) | 1999-06-24 |
| IS5510A (is) | 2000-05-25 |
| WO1999031122A9 (en) | 1999-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |