TR200200751T2 - Panto bileşiklerinin üretilmesi için yöntemler ve mikroorganizmalar. - Google Patents
Panto bileşiklerinin üretilmesi için yöntemler ve mikroorganizmalar.Info
- Publication number
- TR200200751T2 TR200200751T2 TR2002/00751T TR200200751T TR200200751T2 TR 200200751 T2 TR200200751 T2 TR 200200751T2 TR 2002/00751 T TR2002/00751 T TR 2002/00751T TR 200200751 T TR200200751 T TR 200200751T TR 200200751 T2 TR200200751 T2 TR 200200751T2
- Authority
- TR
- Turkey
- Prior art keywords
- microorganisms
- methods
- biosynthetic pathway
- compounds
- panto
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
- C12N9/1014—Hydroxymethyl-, formyl-transferases (2.1.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
Abstract
Mevcut bulus, pantitenat biyosentetik yolaginin ve/veya izolösinvalin biyosentetik yolaginin ve/veya koenzimA biyosentetik yolaginin degistirildigi mikroorganizmalar kullanilarak panto-bilesiklerini )örn., pantotenat) üretme yöntemlerini ön plana çikartir. Ketopantoat redüktaz asiri sunum mikroorganizmalarini ve ayni zamanda aspartat-a-dekarboksilaz asiri sunum mikroorganizmalarini ön plana çikartan yöntemler saglanir. Ön maddeden bagimsiz ve yüksek verimde pantobilesikleri üretme yöntemleri tarif edilir. Yukaridaki metodolojileri uygulamada kullanilan rekombinant mikroorganizmalar, vektörler, izole edilmis nükleik asit molekülleri, genler ve gen ürünleri de saglanir. Mevcut bulus ayni zamanda, modifiye edilmis pantotenat kinaz etkinligine sahip olan mikroorganizmalardan faydalinarak panto-bilesikleri üretme yöntemlerine ilaveten, önceden tanilanmis mikrobik pantotenat kinaz geni coaX'i içerir.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40049499A | 1999-09-21 | 1999-09-21 | |
US21007200P | 2000-06-07 | 2000-06-07 | |
US22183600P | 2000-07-28 | 2000-07-28 | |
US22786000P | 2000-08-24 | 2000-08-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200200751T2 true TR200200751T2 (tr) | 2004-08-23 |
Family
ID=27498789
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2002/00751T TR200200751T2 (tr) | 1999-09-21 | 2000-09-21 | Panto bileşiklerinin üretilmesi için yöntemler ve mikroorganizmalar. |
Country Status (16)
Country | Link |
---|---|
EP (2) | EP1214420B1 (tr) |
JP (1) | JP5392957B2 (tr) |
KR (1) | KR20020092912A (tr) |
CN (1) | CN1420931A (tr) |
AU (1) | AU7708700A (tr) |
BR (1) | BRPI0014115B8 (tr) |
CA (1) | CA2385497A1 (tr) |
CZ (1) | CZ20021013A3 (tr) |
HU (1) | HU230509B1 (tr) |
IL (1) | IL148786A0 (tr) |
MX (1) | MXPA02003017A (tr) |
NO (1) | NO20021382L (tr) |
PL (1) | PL356566A1 (tr) |
SK (1) | SK5222002A3 (tr) |
TR (1) | TR200200751T2 (tr) |
WO (1) | WO2001021772A2 (tr) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
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US6830898B2 (en) * | 2000-08-24 | 2004-12-14 | Omnigene Bioproducts, Inc. | Microorganisms and assays for the identification of antibiotics |
DE10101501A1 (de) * | 2001-01-12 | 2002-08-01 | Forschungszentrum Juelich Gmbh | Verfahren zur fermentativen Herstellung von Pantothensäure |
HU230549B1 (hu) * | 2001-01-19 | 2016-11-28 | Basf Ag | Javított eljárások pantotenát előállítására |
JP4229700B2 (ja) * | 2001-01-19 | 2009-02-25 | ビーエーエスエフ ソシエタス・ヨーロピア | パントテネートの産生増強のための微生物と方法 |
DE10108225A1 (de) | 2001-02-21 | 2002-10-10 | Basf Ag | Verfahren zur Herstellung von D-Pantothensäure und/oder deren Salze als Zusatz zu Tierfuttermitteln |
DE50209165D1 (de) | 2001-02-21 | 2007-02-15 | Basf Ag | Verfahren zur herstellung von d-pantothensäure und/oder salze als zusatz zu tierfuttermitteln |
DE10108223A1 (de) * | 2001-02-21 | 2002-10-10 | Basf Ag | Verfahren zur Herstellung von D-Pantothensäure und/oder deren Salze als Zusatz zu Tierfuttermitteln |
HUP0303334A3 (en) | 2001-02-21 | 2007-09-28 | Basf Ag | Method for producing d-pantothenic caid and/or salts thereof as an additive for animal feed |
EP1247868A3 (de) * | 2001-04-03 | 2002-10-30 | Degussa AG | Verfahren zur fermentativen Herstellung von D-Pantothensäure und/oder deren Salzen |
WO2003004672A1 (en) * | 2001-07-03 | 2003-01-16 | Degussa Ag | Process for the fermentative preparation of d-pantothenic acid and/or salts thereof |
WO2003004673A1 (en) * | 2001-07-03 | 2003-01-16 | Degussa Ag | Process for the fermentative preparation of d-pantothenic acid and/or salts thereof |
DE10132178A1 (de) | 2001-07-03 | 2003-01-23 | Degussa | Verfahren zur fermantativen Herstellung von D-Pantothensäure und/oder deren Salzen |
WO2003006664A2 (en) * | 2001-07-07 | 2003-01-23 | Degussa Ag | Process for the preparation of d-pantothenic acid and/or salts thereof |
EP1672073A1 (en) * | 2001-07-07 | 2006-06-21 | Degussa AG | Process for the preparation of D-pantothenic acid and/or salts thereof |
CA2473716A1 (en) | 2002-01-18 | 2003-07-31 | Cargill, Incorporated | Alanine 2,3- aminomutase |
WO2004005525A2 (en) | 2002-07-03 | 2004-01-15 | Basf Aktiengesellschaft | Microorganisms and processes for enhanced production of pantothenate |
EP1520030B1 (en) * | 2002-07-03 | 2011-10-26 | Basf Se | Microorganisms and processes for enhanced production of pantothenate |
WO2004113510A2 (en) * | 2003-06-18 | 2004-12-29 | Dsm Ip Assets B.V. | Production of pantothenate using microorganisms incapable of sporulation |
EP1876235A4 (en) * | 2005-03-29 | 2008-07-09 | Kaneka Corp | NOVEL GENE OF PANTOTHENATE KINASE AND USE THEREOF |
US9303225B2 (en) | 2005-10-26 | 2016-04-05 | Butamax Advanced Biofuels Llc | Method for the production of isobutanol by recombinant yeast |
US8273558B2 (en) | 2005-10-26 | 2012-09-25 | Butamax(Tm) Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
MX359740B (es) | 2005-10-26 | 2018-10-09 | Du Pont | Produccion fermentativa de alcoholes de cuatro atomos de carbono. |
WO2007131750A1 (en) | 2006-05-16 | 2007-11-22 | Dsm Ip Assets B.V. | Process for the production of panthenol |
EP1918383A1 (en) * | 2006-11-02 | 2008-05-07 | DSMIP Assets B.V. | Semi-continuous fermentation process for pantothenate production |
CN103540559A (zh) | 2007-02-09 | 2014-01-29 | 加利福尼亚大学董事会 | 利用重组微生物生产生物燃料 |
PT2164975E (pt) | 2007-07-06 | 2012-03-08 | Basf Se | Processo para a produção de uma solução aquosa de glicose |
WO2009151728A2 (en) * | 2008-03-27 | 2009-12-17 | Genomatica, Inc. | Microorganisms for the production of adipic acid and other compounds |
EP2157174A1 (en) | 2008-08-12 | 2010-02-24 | DSM IP Assets B.V. | Increased production of pantothenate (vitamin B5) |
WO2012109176A2 (en) * | 2011-02-07 | 2012-08-16 | William Marsh Rice University | Reverse beta oxidation pathway |
US8765426B2 (en) * | 2011-04-07 | 2014-07-01 | E I Du Pont De Nemours And Company | Pantothenic acid biosynthesis in zymomonas |
WO2012175575A2 (en) | 2011-06-21 | 2012-12-27 | Dsm Ip Assets B.V. | Increased vitamin b5 production |
WO2012175574A1 (en) | 2011-06-21 | 2012-12-27 | Dsm Ip Assets B.V. | Increased pantothenate (vitamin b5) production |
WO2014087184A1 (en) * | 2012-12-03 | 2014-06-12 | Metabolic Explorer | Neopentyl glycol fermentative production by a recombinant microorganism |
EP3060570B1 (en) | 2013-10-25 | 2018-09-19 | Retrophin, Inc. | Pantothenate derivatives for the treatment of neurological disorders |
CN104593398B (zh) * | 2013-11-01 | 2017-06-06 | 中国科学院微生物研究所 | 一种高L‑天冬氨酸α羧化酶活性的工程菌及其在生产β‑丙氨酸中的应用 |
CN105368758B (zh) * | 2015-03-16 | 2018-06-19 | 鲁东大学 | 一株高产天冬氨酸脱羧酶的菌株及用于生产丙氨酸的方法 |
CN108486110A (zh) * | 2015-03-31 | 2018-09-04 | 中国农业科学院生物技术研究所 | 一种启动子和重组表达载体及其用途 |
MX2018006636A (es) | 2015-12-08 | 2018-08-15 | Retrophin Inc | Fosfatos ciclicos y fosforoamidatos ciclicos para el tratamiento de trastornos neurologicos. |
JP2020530271A (ja) | 2017-06-30 | 2020-10-22 | ピーティーティー グローバル ケミカル パブリック カンパニー リミテッド | 安定化されたコピー数の機能性dna配列を有する微生物及び関連方法 |
CN108456701B (zh) * | 2018-03-23 | 2020-10-16 | 精晶药业股份有限公司 | 一种d-泛解酸内酯的制备方法 |
WO2020005834A1 (en) * | 2018-06-25 | 2020-01-02 | Lygos, Inc. | RECOMBINANT HOST CELLS AND METHODS FOR THE PRODUCTION OF ASPARTIC ACID AND β-ALANINE |
SG11202012136YA (en) * | 2018-07-09 | 2021-01-28 | Codexis Inc | Engineered pantothenate kinase variant enzymes |
EP4174185A1 (en) | 2020-06-28 | 2023-05-03 | Mint BioTech Ltd. | Methods for preparing pantoic acid, pantothenic acid and panthenol as well as salts thereof |
KR102389327B1 (ko) * | 2020-07-01 | 2022-04-20 | 씨제이제일제당 (주) | 3-메틸-2-옥소뷰타노에이트 하이드록시 메틸트랜스퍼라아제의 활성이 강화된 미생물, 및 이의 용도 |
CN115109736B (zh) * | 2021-03-23 | 2024-05-07 | 中国科学院天津工业生物技术研究所 | 一种产泛解酸的微生物及其构建方法和应用 |
EP4323331A1 (en) | 2021-04-15 | 2024-02-21 | DSM IP Assets B.V. | Production of panthenol |
EP4108654A1 (en) | 2021-06-23 | 2022-12-28 | DSM IP Assets B.V. | Production of panthenol |
CN114085820B (zh) * | 2021-11-19 | 2023-10-20 | 万华化学集团股份有限公司 | 来源于Candida viswanathii的酮基泛解酸内酯还原酶 |
CN114437988B (zh) * | 2022-02-28 | 2023-05-23 | 贵州医科大学 | 纤维素降解菌及菌剂、制备方法、应用和降解酒糟的方法 |
CN115595314A (zh) * | 2022-03-07 | 2023-01-13 | 中国科学院微生物研究所(Cn) | 表达天冬氨酸脱氢酶的工程菌及发酵生产维生素b5的方法 |
CN115595328A (zh) * | 2022-03-07 | 2023-01-13 | 中国科学院微生物研究所(Cn) | 天冬氨酸脱羧酶在发酵生产维生素b5中的应用 |
Family Cites Families (7)
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US5024943A (en) * | 1985-11-07 | 1991-06-18 | Gist-Brocades | Regulatory region cloning and analysis plasmid for bacillus |
US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
JP3710497B2 (ja) * | 1992-09-25 | 2005-10-26 | ビーエーエスエフ アクチェンゲゼルシャフト | D−パント酸、d−パントテン酸およびそれらの塩の製造法 |
SK30598A3 (en) | 1995-09-13 | 1999-01-11 | Takeda Chemical Industries Ltd | Process for producing d-pantoic acid and d-pantothenic acid or salts thereof |
US5834259A (en) * | 1996-10-28 | 1998-11-10 | Monsanto Company | Process and composition for preparing D-aspartic acid |
DE19855313A1 (de) * | 1998-12-01 | 2000-06-08 | Degussa | Verfahren zur fermentativen Herstellung von D-Pantothensäure durch Verstärkung des panD-Gens in Mikroorganismen |
DE19855312A1 (de) * | 1998-12-01 | 2000-06-08 | Degussa | Verfahren zur fermentativen Herstellung von D-Pantothensäure unter Verwendung coryneformer Bakterien |
-
2000
- 2000-09-21 IL IL14878600A patent/IL148786A0/xx unknown
- 2000-09-21 SK SK522-2002A patent/SK5222002A3/sk unknown
- 2000-09-21 MX MXPA02003017A patent/MXPA02003017A/es unknown
- 2000-09-21 TR TR2002/00751T patent/TR200200751T2/tr unknown
- 2000-09-21 HU HU0202705A patent/HU230509B1/hu not_active IP Right Cessation
- 2000-09-21 BR BRPI0014115A patent/BRPI0014115B8/pt not_active IP Right Cessation
- 2000-09-21 WO PCT/US2000/025993 patent/WO2001021772A2/en not_active Application Discontinuation
- 2000-09-21 CN CN00815771A patent/CN1420931A/zh active Pending
- 2000-09-21 CZ CZ20021013A patent/CZ20021013A3/cs unknown
- 2000-09-21 CA CA002385497A patent/CA2385497A1/en not_active Abandoned
- 2000-09-21 EP EP00966799.9A patent/EP1214420B1/en not_active Expired - Lifetime
- 2000-09-21 EP EP09179840.5A patent/EP2163629B1/en not_active Expired - Lifetime
- 2000-09-21 AU AU77087/00A patent/AU7708700A/en not_active Abandoned
- 2000-09-21 JP JP2001525331A patent/JP5392957B2/ja not_active Expired - Fee Related
- 2000-09-21 KR KR1020027003732A patent/KR20020092912A/ko not_active Application Discontinuation
- 2000-09-21 PL PL00356566A patent/PL356566A1/xx not_active Application Discontinuation
-
2002
- 2002-03-20 NO NO20021382A patent/NO20021382L/no unknown
Also Published As
Publication number | Publication date |
---|---|
EP1214420A2 (en) | 2002-06-19 |
CA2385497A1 (en) | 2001-03-29 |
HUP0202705A2 (hu) | 2002-12-28 |
NO20021382L (no) | 2002-05-16 |
HU230509B1 (hu) | 2016-09-28 |
WO2001021772A9 (en) | 2002-12-05 |
CN1420931A (zh) | 2003-05-28 |
EP2163629A3 (en) | 2010-06-02 |
KR20020092912A (ko) | 2002-12-12 |
NO20021382D0 (no) | 2002-03-20 |
IL148786A0 (en) | 2002-09-12 |
EP2163629B1 (en) | 2017-03-08 |
PL356566A1 (en) | 2004-06-28 |
EP1214420B1 (en) | 2016-03-23 |
SK5222002A3 (en) | 2003-03-04 |
WO2001021772A2 (en) | 2001-03-29 |
HUP0202705A3 (en) | 2011-02-28 |
BRPI0014115B8 (pt) | 2021-05-25 |
EP2163629A2 (en) | 2010-03-17 |
WO2001021772A3 (en) | 2002-03-07 |
JP5392957B2 (ja) | 2014-01-22 |
MXPA02003017A (es) | 2004-09-06 |
JP2003527828A (ja) | 2003-09-24 |
BRPI0014115B1 (pt) | 2015-05-05 |
BR0014115A (pt) | 2002-05-21 |
CZ20021013A3 (en) | 2002-12-11 |
AU7708700A (en) | 2001-04-24 |
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