DK1023292T3 - Fremgangsmåde til syntese af chlorpurinintermediater - Google Patents

Fremgangsmåde til syntese af chlorpurinintermediater

Info

Publication number
DK1023292T3
DK1023292T3 DK98949093T DK98949093T DK1023292T3 DK 1023292 T3 DK1023292 T3 DK 1023292T3 DK 98949093 T DK98949093 T DK 98949093T DK 98949093 T DK98949093 T DK 98949093T DK 1023292 T3 DK1023292 T3 DK 1023292T3
Authority
DK
Denmark
Prior art keywords
chlorpurin
intermediates
synthesis
chlorpurin intermediates
Prior art date
Application number
DK98949093T
Other languages
Danish (da)
English (en)
Inventor
Martin Francis Jones
Christopher John Wallis
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DK1023292T3 publication Critical patent/DK1023292T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK98949093T 1997-10-14 1998-10-14 Fremgangsmåde til syntese af chlorpurinintermediater DK1023292T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9721780.6A GB9721780D0 (en) 1997-10-14 1997-10-14 Process for the synthesis of chloropurine intermediates
PCT/GB1998/003080 WO1999019327A1 (fr) 1997-10-14 1998-10-14 Procede de synthese d'intermediaires de la chloropurine

Publications (1)

Publication Number Publication Date
DK1023292T3 true DK1023292T3 (da) 2003-11-10

Family

ID=10820547

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98949093T DK1023292T3 (da) 1997-10-14 1998-10-14 Fremgangsmåde til syntese af chlorpurinintermediater

Country Status (44)

Country Link
US (1) US6646125B1 (fr)
EP (1) EP1023292B1 (fr)
JP (1) JP4531250B2 (fr)
KR (1) KR100543845B1 (fr)
CN (1) CN1160354C (fr)
AP (1) AP1182A (fr)
AR (1) AR014921A1 (fr)
AT (1) ATE249461T1 (fr)
AU (1) AU738462B2 (fr)
BG (1) BG64597B1 (fr)
BR (1) BR9813048B1 (fr)
CA (1) CA2306958C (fr)
CO (1) CO4980899A1 (fr)
CZ (1) CZ294482B6 (fr)
DE (1) DE69818084T2 (fr)
DK (1) DK1023292T3 (fr)
EA (1) EA003183B1 (fr)
EE (1) EE04059B1 (fr)
EG (1) EG21730A (fr)
ES (1) ES2205553T3 (fr)
GB (1) GB9721780D0 (fr)
GE (1) GEP20022679B (fr)
HK (1) HK1027807A1 (fr)
HR (1) HRP20000216B1 (fr)
HU (1) HUP0003984A3 (fr)
ID (1) ID24927A (fr)
IL (1) IL135323A (fr)
IN (1) IN184590B (fr)
IS (1) IS2195B (fr)
MA (1) MA24676A1 (fr)
MY (1) MY127470A (fr)
NO (1) NO325030B1 (fr)
NZ (1) NZ503679A (fr)
OA (1) OA11370A (fr)
PE (1) PE121899A1 (fr)
PL (1) PL188477B1 (fr)
PT (1) PT1023292E (fr)
RS (1) RS49710B (fr)
SK (1) SK285331B6 (fr)
TR (1) TR200000976T2 (fr)
TW (1) TW436488B (fr)
UA (1) UA54550C2 (fr)
WO (1) WO1999019327A1 (fr)
ZA (1) ZA989338B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK284416B6 (sk) * 1997-11-27 2005-03-04 Lonza Ag Spôsob výroby derivátov aminoalkoholov
FR2849030A1 (fr) * 2002-12-20 2004-06-25 Isochem Sa Procede de preparation des n-(2-amino-4, 6-dihalogenopyrimidin-5-yl) formamides
GB0320738D0 (en) * 2003-09-04 2003-10-08 Glaxo Group Ltd Novel process
CN100465174C (zh) * 2006-06-13 2009-03-04 中国科学院上海有机化学研究所 制备光学纯阿巴卡韦的方法
KR101109476B1 (ko) * 2009-06-26 2012-01-31 현대제철 주식회사 실린더 교체용 지그장치
RS54123B1 (en) 2010-01-27 2015-12-31 Viiv Healthcare Company THERAPEUTIC COMBINATION CONTAINING DOLUTEGRAVIR, ABACAVIR AND LAMIVUDINE
CN104672239A (zh) * 2013-11-26 2015-06-03 上海迪赛诺化学制药有限公司 一种采用一锅法制备阿巴卡韦式v中间体的工艺

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268672A (en) * 1977-02-09 1981-05-19 The Regents Of The University Of Minnesota Adenosine deaminase resistant antiviral purine nucleosides and method of preparation
JPS6175A (ja) * 1984-03-06 1986-01-06 ブリストル−マイア−ズ　コムパニ− 神経弛緩剤、１‐フルオロフェニルブチル‐４‐（５‐ハロ‐２‐ピリミジニル）ピペラジン誘導体
US5631370A (en) 1988-01-20 1997-05-20 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
NO169123C (no) * 1988-01-20 1992-05-13 Univ Minnesota Analogifremgangsmaate til fremstilling av terapeutisk aktive karbocykliske 2',3'-dideoksy-2',3'-didehydropurinnukleosidanaloger
NZ229453A (en) * 1988-06-10 1991-08-27 Univ Minnesota & Southern Rese A pharmaceutical composition containing purine derivatives with nucleosides such as azt, as antiviral agents
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
MY104575A (en) * 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.
US5126452A (en) * 1990-04-06 1992-06-30 Glaxo Inc. Synthesis of purine substituted cyclopentene derivatives
US5329008A (en) 1993-04-07 1994-07-12 Glaxo Inc. Synthesis of a 3,4-dihydroxy-1-cyclopentanylpurinone
GB9402161D0 (en) * 1994-02-04 1994-03-30 Wellcome Found Chloropyrimidine intermediates
SK285228B6 (sk) * 1997-05-13 2006-09-07 Lonza Ag Spôsob výroby racemického alebo opticky aktívnehoderivátu 4-(hydroxymetyl)-2-cyklopenténu a racemicky N-butyryl-1-amino-4- (hydroxymetyl)-2-cyklopentén

Also Published As

Publication number Publication date
NZ503679A (en) 2002-09-27
ID24927A (id) 2000-08-31
IL135323A (en) 2004-07-25
CO4980899A1 (es) 2000-11-27
TW436488B (en) 2001-05-28
NO20001896D0 (no) 2000-04-12
CA2306958C (fr) 2007-09-04
MY127470A (en) 2006-12-29
PL339904A1 (en) 2001-01-15
KR100543845B1 (ko) 2006-01-23
CZ20001367A3 (cs) 2000-10-11
BG104352A (en) 2001-02-28
EP1023292B1 (fr) 2003-09-10
AP1182A (en) 2003-06-18
HUP0003984A3 (en) 2002-12-28
WO1999019327A1 (fr) 1999-04-22
OA11370A (en) 2004-01-27
EA003183B1 (ru) 2003-02-27
ES2205553T3 (es) 2004-05-01
YU20200A (sh) 2003-02-28
BR9813048B1 (pt) 2010-07-13
DE69818084D1 (de) 2003-10-16
IN184590B (fr) 2000-09-09
CA2306958A1 (fr) 1999-04-22
DE69818084T2 (de) 2004-07-15
GEP20022679B (en) 2002-04-25
EA200000318A1 (ru) 2000-12-25
NO20001896L (no) 2000-06-13
AP2000001790A0 (en) 2000-06-30
JP2001519432A (ja) 2001-10-23
MA24676A1 (fr) 1999-07-01
PL188477B1 (pl) 2005-02-28
HUP0003984A2 (hu) 2001-04-28
NO325030B1 (no) 2008-01-21
EP1023292A1 (fr) 2000-08-02
HK1027807A1 (en) 2001-01-23
BR9813048A (pt) 2000-08-15
CN1160354C (zh) 2004-08-04
ZA989338B (en) 2000-04-13
ATE249461T1 (de) 2003-09-15
EE200000162A (et) 2001-04-16
RS49710B (sr) 2007-12-31
CN1281457A (zh) 2001-01-24
AU9547698A (en) 1999-05-03
KR20010015744A (ko) 2001-02-26
IL135323A0 (en) 2001-05-20
EG21730A (en) 2002-02-27
HRP20000216B1 (en) 2002-08-31
BG64597B1 (bg) 2005-08-31
HRP20000216A2 (en) 2000-08-31
IS2195B (is) 2007-01-15
JP4531250B2 (ja) 2010-08-25
SK285331B6 (sk) 2006-11-03
AU738462B2 (en) 2001-09-20
US6646125B1 (en) 2003-11-11
UA54550C2 (uk) 2003-03-17
CZ294482B6 (cs) 2005-01-12
PE121899A1 (es) 1999-12-20
TR200000976T2 (tr) 2000-11-21
GB9721780D0 (en) 1997-12-10
PT1023292E (pt) 2004-02-27
AR014921A1 (es) 2001-04-11
IS5423A (is) 2000-03-28
SK5362000A3 (en) 2001-03-12
EE04059B1 (et) 2003-06-16

Similar Documents

Publication Publication Date Title
DK0922040T3 (da) Fremgangsmåde til fremstilling af mellemprodukter til florfenicol
DK0773940T4 (da) Fremgangsmåde til syntese af substituerede sulfoxider
DK1032566T3 (da) Fremgangsmåde til fremstilling af citalopram
DK1054860T3 (da) Proces for syntesen af 1,3-dioler
DK0885968T3 (da) Fremgangsmåde til fremstilling af vanillin
DK0770615T3 (da) Fremgangsmåde til fremstilling af dihalogenazolopyrimidiner
DK1038008T3 (da) Fremgangsmåde til fremstilling af EGIII-lignende enzymer
DK0790226T3 (da) Fremgangsmåde til fremstilling af methanol
FI19992060A (fi) Prosessikojeen alusta
DK1005517T3 (da) Fremgangsmåde til fremstilling af diglycerider
DK0971913T3 (da) Fremgangsmåde til fremstillingen af semisyntetiske statiner via hidtil ukendte mellemprodukter
DK0788496T3 (da) Inhibitorer for syntese af apolipoprotein-B
DK0983059T3 (da) Fremgangsmåde til fremstilling af flurbiprofen sugetabletter
DK0991640T3 (da) Syntese af mellemprodukter, der er anvendelige til fremstilling af bromsubstituerede tricykliske forbindelser
DK1053217T3 (da) Fremgangsmåde til fremstilling af n-propanol
DK0996642T3 (da) Fremgangsmåde til fremstilling af heparin
DK1027315T3 (da) Fremgangsmåde til fremstilling af n-butanol
DK1028960T3 (da) Fremgangsmåde til fremstilling af thiazolidinedion
DK0966445T3 (da) Fremgangsmåder til fremstilling af mellemprodukter til pesticider
DK0970939T3 (da) Fremgangsmåde til fremstilling af methanol
DK1023292T3 (da) Fremgangsmåde til syntese af chlorpurinintermediater
DK0842930T3 (da) Fremgangsmåde til syntese af benzothiophener
DK0927766T3 (da) Enzymatisk fremgangsmåde til fremstilling af (S)-cyanhydriner
DK0973769T3 (da) Fremgangsmåde til fremstilling af eprosartan
IT1295934B1 (it) Procedimento migliorato per la sintesi di alchilpoliglucosidi