DK0991640T3 - Syntese af mellemprodukter, der er anvendelige til fremstilling af bromsubstituerede tricykliske forbindelser - Google Patents

Syntese af mellemprodukter, der er anvendelige til fremstilling af bromsubstituerede tricykliske forbindelser

Info

Publication number
DK0991640T3
DK0991640T3 DK98928873T DK98928873T DK0991640T3 DK 0991640 T3 DK0991640 T3 DK 0991640T3 DK 98928873 T DK98928873 T DK 98928873T DK 98928873 T DK98928873 T DK 98928873T DK 0991640 T3 DK0991640 T3 DK 0991640T3
Authority
DK
Denmark
Prior art keywords
brake
synthesis
preparation
intermediates useful
tricyclic compounds
Prior art date
Application number
DK98928873T
Other languages
English (en)
Inventor
Xing Chen
Yee-Shing Wong
Guang-Zhong Wu
Marc Poirier
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DK0991640T3 publication Critical patent/DK0991640T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK98928873T 1997-06-16 1998-06-15 Syntese af mellemprodukter, der er anvendelige til fremstilling af bromsubstituerede tricykliske forbindelser DK0991640T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/882,753 US5760232A (en) 1997-06-16 1997-06-16 Synthesis of intermediates useful in preparing bromo-substituted tricyclic compounds
PCT/US1998/011403 WO1998057958A1 (en) 1997-06-16 1998-06-15 Synthesis of intermediates useful in preparing bromo-substituted tricyclic compounds

Publications (1)

Publication Number Publication Date
DK0991640T3 true DK0991640T3 (da) 2002-05-27

Family

ID=25381267

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98928873T DK0991640T3 (da) 1997-06-16 1998-06-15 Syntese af mellemprodukter, der er anvendelige til fremstilling af bromsubstituerede tricykliske forbindelser

Country Status (15)

Country Link
US (1) US5760232A (da)
EP (1) EP0991640B1 (da)
JP (1) JP3210023B2 (da)
AR (1) AR015886A1 (da)
AT (1) ATE214062T1 (da)
AU (1) AU8056898A (da)
CA (1) CA2293709C (da)
DE (1) DE69804100T2 (da)
DK (1) DK0991640T3 (da)
ES (1) ES2169917T3 (da)
IN (1) IN187755B (da)
MY (1) MY133531A (da)
PT (1) PT991640E (da)
WO (1) WO1998057958A1 (da)
ZA (1) ZA985207B (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5998620A (en) * 1997-03-25 1999-12-07 Schering Corporation Synthesis of intermediates useful in preparing tricyclic compounds
ATE365157T1 (de) * 2002-10-03 2007-07-15 Schering Corp Enantioselective alkylierung von trizyklischen verbindungen
ES2790358T3 (es) 2011-12-28 2020-10-27 Global Blood Therapeutics Inc Compuestos de heteroaril aldehído sustituido y métodos para su uso en el aumento de la oxigenación tisular
LT2797416T (lt) 2011-12-28 2017-10-25 Global Blood Therapeutics, Inc. Pakeistieji benzaldehido junginiai ir jų panaudojimo būdai, didinant audinių aprūpinimą deguonimi
US10266551B2 (en) 2013-03-15 2019-04-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9422279B2 (en) 2013-03-15 2016-08-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9458139B2 (en) 2013-03-15 2016-10-04 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
MX2015011445A (es) 2013-03-15 2016-04-20 Global Blood Therapeutics Inc Compuestos y usos de estos para la modulacion de la hemoglobina.
WO2014145040A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
US20140274961A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
KR20150132146A (ko) 2013-03-15 2015-11-25 글로벌 블러드 테라퓨틱스, 인크. 헤모글로빈 조정을 위한 화합물 및 이의 용도
AU2014237348C1 (en) 2013-03-15 2019-02-07 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9802900B2 (en) 2013-03-15 2017-10-31 Global Blood Therapeutics, Inc. Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
US9604999B2 (en) 2013-03-15 2017-03-28 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
EA201992707A1 (ru) 2013-11-18 2020-06-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
BR112015032160B1 (pt) 2014-02-07 2021-11-30 Global Blood Therapeutics, Inc Ansolvato cristalino de composto, composição e composição farmacêutica
MA41841A (fr) 2015-03-30 2018-02-06 Global Blood Therapeutics Inc Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs
MA43373A (fr) 2015-12-04 2018-10-10 Global Blood Therapeutics Inc Régimes posologiques pour 2-hydroxy-6-((2- (1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)méthoxy)benzaldéhyde
TWI663160B (zh) 2016-05-12 2019-06-21 全球血液治療公司 用於合成2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)-吡啶-3-基)甲氧基)苯甲醛之方法
TW202332423A (zh) 2016-10-12 2023-08-16 美商全球血液治療公司 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
WO2020072377A1 (en) 2018-10-01 2020-04-09 Global Blood Therapeutics, Inc. Modulators of hemoglobin for the treatment of sickle cell disease
CN112341433A (zh) * 2020-11-16 2021-02-09 成都大学 一种氯雷他定的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5089496A (en) * 1986-10-31 1992-02-18 Schering Corporation Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies
TW308594B (da) * 1993-10-15 1997-06-21 Schering Corp
IL111235A (en) * 1993-10-15 2001-03-19 Schering Plough Corp Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them
IL125062A (en) * 1995-12-22 2003-11-23 Schering Corp Tricyclic amides and pharmaceutical compositions containing them for inhibition of g-protein function and for treatment of proliferative diseases

Also Published As

Publication number Publication date
PT991640E (pt) 2002-07-31
US5760232A (en) 1998-06-02
AR015886A1 (es) 2001-05-30
ES2169917T3 (es) 2002-07-16
WO1998057958A1 (en) 1998-12-23
IN187755B (da) 2002-06-15
CA2293709C (en) 2004-02-10
JP2000513032A (ja) 2000-10-03
AU8056898A (en) 1999-01-04
EP0991640A1 (en) 2000-04-12
EP0991640B1 (en) 2002-03-06
DE69804100T2 (de) 2002-10-31
ZA985207B (en) 1999-04-07
MY133531A (en) 2007-11-30
CA2293709A1 (en) 1998-12-23
ATE214062T1 (de) 2002-03-15
JP3210023B2 (ja) 2001-09-17
DE69804100D1 (de) 2002-04-11

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