DK0788496T3 - Inhibitorer for syntese af apolipoprotein-B - Google Patents
Inhibitorer for syntese af apolipoprotein-BInfo
- Publication number
- DK0788496T3 DK0788496T3 DK95937804T DK95937804T DK0788496T3 DK 0788496 T3 DK0788496 T3 DK 0788496T3 DK 95937804 T DK95937804 T DK 95937804T DK 95937804 T DK95937804 T DK 95937804T DK 0788496 T3 DK0788496 T3 DK 0788496T3
- Authority
- DK
- Denmark
- Prior art keywords
- apolipoprotein
- inhibitors
- synthesis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP94203120 | 1994-10-27 | ||
| US08/455,304 US5521186A (en) | 1994-10-27 | 1995-05-31 | Apolipoprotein-β synthesis inhibitors |
| PCT/EP1995/004111 WO1996013499A1 (en) | 1994-10-27 | 1995-10-19 | Apolipoprotein-b synthesis inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0788496T3 true DK0788496T3 (da) | 2001-06-18 |
Family
ID=26136684
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95937804T DK0788496T3 (da) | 1994-10-27 | 1995-10-19 | Inhibitorer for syntese af apolipoprotein-B |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US5929075A (da) |
| EP (1) | EP0788496B1 (da) |
| JP (1) | JP3025907B2 (da) |
| KR (1) | KR100227231B1 (da) |
| CN (1) | CN1068000C (da) |
| AP (1) | AP779A (da) |
| AT (1) | ATE198889T1 (da) |
| AU (1) | AU697744C (da) |
| BG (1) | BG63694B1 (da) |
| BR (1) | BR9509436A (da) |
| CA (1) | CA2203274C (da) |
| CY (1) | CY2256B1 (da) |
| CZ (1) | CZ286476B6 (da) |
| DE (3) | DE122007000005I2 (da) |
| DK (1) | DK0788496T3 (da) |
| ES (1) | ES2155535T3 (da) |
| FI (1) | FI119548B (da) |
| GR (1) | GR3035519T3 (da) |
| HR (1) | HRP950532B1 (da) |
| HU (1) | HU219862B (da) |
| IL (1) | IL115771A (da) |
| LU (1) | LU91306I2 (da) |
| NO (1) | NO311937B1 (da) |
| NZ (1) | NZ295353A (da) |
| OA (1) | OA10479A (da) |
| PT (1) | PT788496E (da) |
| RO (1) | RO118715B1 (da) |
| SK (1) | SK281908B6 (da) |
| TR (1) | TR199501295A2 (da) |
| WO (1) | WO1996013499A1 (da) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010023661A (ko) * | 1997-11-03 | 2001-03-26 | 디르크 반테 | 지질 저하제 조성물 |
| AU3710099A (en) * | 1998-04-27 | 1999-11-16 | Janssen Pharmaceutica N.V. | Pellets having a core coated with a lipid lowering agent and a polymer |
| NZ512891A (en) * | 1998-12-22 | 2003-01-31 | Janssen Pharmaceutica Nv | S-oxide lipid lowering compounds |
| DE19945982A1 (de) | 1999-09-24 | 2001-03-29 | Knoll Ag | Geschwindigkeitsbestimmte Partikel |
| US20050132022A1 (en) * | 2003-12-12 | 2005-06-16 | International Business Machines Corporation | Computer system with LAN-based I/O |
| WO2005070390A2 (en) * | 2004-01-21 | 2005-08-04 | Janssen Pharmaceutica N.V. | Mitratapide oral solution |
| US7649002B2 (en) | 2004-02-04 | 2010-01-19 | Pfizer Inc | (3,5-dimethylpiperidin-1yl)(4-phenylpyrrolidin-3-yl)methanone derivatives as MCR4 agonists |
| US7262318B2 (en) * | 2004-03-10 | 2007-08-28 | Pfizer, Inc. | Substituted heteroaryl- and phenylsulfamoyl compounds |
| CA2562015A1 (en) * | 2004-04-09 | 2005-10-20 | Janssen Pharmaceutica Nv | Intermittent dosing regimens of apob secretion/mtp inhibitors for overweith and obese subjects |
| US20050288340A1 (en) * | 2004-06-29 | 2005-12-29 | Pfizer Inc | Substituted heteroaryl- and phenylsulfamoyl compounds |
| PA8660701A1 (es) | 2005-02-04 | 2006-09-22 | Pfizer Prod Inc | Agonistas de pyy y sus usos |
| JP2008542255A (ja) * | 2005-05-27 | 2008-11-27 | ファイザー・プロダクツ・インク | 肥満症の治療または体重減量の維持のためのカンナビノイド−１受容体アンタゴニストおよびミクロソームトリグリセリド輸送タンパク質阻害物質の併用 |
| JP2009503050A (ja) * | 2005-08-04 | 2009-01-29 | ファイザー・リミテッド | ピペリジノイル−ピロリジンおよびピペリジノイル−ピペリジン化合物 |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| WO2007096763A2 (en) * | 2006-02-23 | 2007-08-30 | Pfizer Limited | Melanocortin type 4 receptor agonist piperidinoylpyrrolidines |
| US8383660B2 (en) | 2006-03-10 | 2013-02-26 | Pfizer Inc. | Dibenzyl amine compounds and derivatives |
| AU2007320906A1 (en) | 2006-11-13 | 2008-05-22 | Pfizer Products Inc. | Diaryl, dipyridinyl and aryl-pyridinyl derivatives and uses thereof |
| ATE547394T1 (de) | 2006-12-01 | 2012-03-15 | Bristol Myers Squibb Co | N-((3-benzyl)-2,2-(bis-phenyl)-propan-1- aminderivate als cetp-hemmer für die behandlung von atherosklerose und herz-kreislauf- erkrankungen |
| BRPI0811902B1 (pt) * | 2007-05-25 | 2020-03-24 | Janssen Pharmaceutica N.V. | Síntese aprimorada do (2s-cis)-2-(bromometil)-2-(-4-clorofenil)-1,3-dioxolano-4-metanol metanosulfonato (éster) |
| DK2326638T5 (da) * | 2008-08-06 | 2014-01-13 | Pfizer Ltd | Diazepin- og diazocan-forbindelser som mc4-agonister |
| CN102906087B (zh) * | 2010-05-19 | 2016-03-23 | 桑多斯股份公司 | 制备手性三唑酮的方法 |
| UA128288C2 (uk) | 2018-03-08 | 2024-05-29 | Інсайт Корпорейшн | СПОЛУКИ АМІНОПІРАЗИНДІОЛУ ЯК ІНГІБІТОРИ PI3K-<font face="Symbol">g</font> |
| US11046658B2 (en) | 2018-07-02 | 2021-06-29 | Incyte Corporation | Aminopyrazine derivatives as PI3K-γ inhibitors |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4313953A (en) * | 1978-06-23 | 1982-02-02 | Janssen Pharmaceutica, N.V. | Heterocyclic derivatives of (4-aryloxymethyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles |
| US4267179A (en) * | 1978-06-23 | 1981-05-12 | Janssen Pharmaceutica, N.V. | Heterocyclic derivatives of (4-phenylpiperazin-1-yl-aryloxymethyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles |
| US4766125A (en) * | 1981-06-23 | 1988-08-23 | Janssen Pharmaceutica N.V. | N-aryl-piperazinealkanamides useful for protecting hearts from myocardial injury caused by ischaemia, anoxia or hypoxia |
| US4619931A (en) * | 1983-02-28 | 1986-10-28 | Janssen Pharmaceutica, N.V. | [[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles |
| CA1292472C (en) * | 1985-12-03 | 1991-11-26 | Alfonsus Guilielmus Knaeps | Derivatives of ¬¬4-¬4-(4-phenyl-1-piperazinyl)- phenoxymethyl|-1,3-dioxolan-2-yl|methyl|-1h-imidazoles and 1h-1,2,4-triazoles |
| NZ223799A (en) * | 1987-03-25 | 1989-12-21 | Janssen Pharmaceutica Nv | Azolylmethyl-dioxolanylmethoxyphenyl-piperazinyl-phenyl-triazolones and antimicrobial compositions |
| CA1331757C (en) * | 1988-02-29 | 1994-08-30 | Janssen Pharmaceutica Naamloze Vennootschap | 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols |
| WO1994020063A2 (en) * | 1993-03-04 | 1994-09-15 | Cytoven International N.V. | Pharmaceutical tryptophan containing dipeptide compositions and methods of use thereof |
| US5521186A (en) * | 1994-10-27 | 1996-05-28 | Janssen Pharmaceutica N.V. | Apolipoprotein-β synthesis inhibitors |
-
1995
- 1995-10-19 JP JP8514288A patent/JP3025907B2/ja not_active Expired - Fee Related
- 1995-10-19 US US08/817,247 patent/US5929075A/en not_active Expired - Lifetime
- 1995-10-19 DE DE122007000005C patent/DE122007000005I2/de active Active
- 1995-10-19 DE DE1995619995 patent/DE122007000005I1/de active Pending
- 1995-10-19 CZ CZ19971198A patent/CZ286476B6/cs not_active IP Right Cessation
- 1995-10-19 NZ NZ295353A patent/NZ295353A/en not_active IP Right Cessation
- 1995-10-19 AP APAP/P/1997/000968A patent/AP779A/en active
- 1995-10-19 AT AT95937804T patent/ATE198889T1/de active
- 1995-10-19 DE DE69519995T patent/DE69519995T2/de not_active Expired - Lifetime
- 1995-10-19 AU AU38680/95A patent/AU697744C/en not_active Ceased
- 1995-10-19 CN CN95195885A patent/CN1068000C/zh not_active Expired - Fee Related
- 1995-10-19 EP EP95937804A patent/EP0788496B1/en not_active Expired - Lifetime
- 1995-10-19 WO PCT/EP1995/004111 patent/WO1996013499A1/en active IP Right Grant
- 1995-10-19 HU HU9701956A patent/HU219862B/hu not_active IP Right Cessation
- 1995-10-19 BR BR9509436A patent/BR9509436A/pt not_active IP Right Cessation
- 1995-10-19 RO RO97-00812A patent/RO118715B1/ro unknown
- 1995-10-19 PT PT95937804T patent/PT788496E/pt unknown
- 1995-10-19 SK SK507-97A patent/SK281908B6/sk not_active IP Right Cessation
- 1995-10-19 KR KR1019970702662A patent/KR100227231B1/ko not_active IP Right Cessation
- 1995-10-19 DK DK95937804T patent/DK0788496T3/da active
- 1995-10-19 CA CA002203274A patent/CA2203274C/en not_active Expired - Fee Related
- 1995-10-19 ES ES95937804T patent/ES2155535T3/es not_active Expired - Lifetime
- 1995-10-20 TR TR95/01295A patent/TR199501295A2/xx unknown
- 1995-10-26 IL IL11577195A patent/IL115771A/xx not_active IP Right Cessation
- 1995-10-27 HR HR950532A patent/HRP950532B1/xx not_active IP Right Cessation
-
1997
- 1997-04-10 BG BG101402A patent/BG63694B1/bg unknown
- 1997-04-24 NO NO19971895A patent/NO311937B1/no not_active IP Right Cessation
- 1997-04-25 OA OA60997A patent/OA10479A/en unknown
- 1997-04-25 FI FI971784A patent/FI119548B/fi not_active IP Right Cessation
-
2001
- 2001-03-05 GR GR20010400359T patent/GR3035519T3/el unknown
-
2002
- 2002-01-04 CY CY0200004A patent/CY2256B1/xx unknown
-
2007
- 2007-01-17 LU LU91306C patent/LU91306I2/fr unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0788496T3 (da) | Inhibitorer for syntese af apolipoprotein-B | |
| DK0773940T3 (da) | Fremgangsmåde til syntese af substituerede sulfoxider | |
| DK1445259T3 (da) | Anvendelse af krystalformer for 2-methyl-thieno-benzodiazepin | |
| LV11178A (lv) | 3-Ú4-(2-aminoetoksi) benzoil¾-2-aril-6-hidroksibenzoÚb¾tiofenu sintezes panemiens | |
| FI963597A0 (fi) | Isoprenyylitransferaasi-inhibiittoreita | |
| NO972930D0 (no) | Fibronectin-adhesjonsinhibitorer | |
| BR9612465A (pt) | Compostos heterocíclicos | |
| FI972160A (fi) | Matriisimetalloproteaasi-inhibiittorit | |
| ID24638A (id) | Senyawa-senyawa anti aritmia bispidina | |
| DK0820451T3 (da) | Hidtil ukendte heterocykliske forbindelser | |
| EE9700093A (et) | Apolipoproteiin-B sünteesi inhiibitorid | |
| NO963187D0 (no) | Fremgangsmåte for syntese av gamma-pyroner | |
| IT1295934B1 (it) | Procedimento migliorato per la sintesi di alchilpoliglucosidi | |
| DK1023292T3 (da) | Fremgangsmåde til syntese af chlorpurinintermediater | |
| BR9708718A (pt) | Sínteses de aminas substituídas | |
| DK0857720T3 (da) | Fremgangsmåde til syntese af desoxypyridinolin | |
| ITMI941144A0 (it) | Procedimento per la formazione di timbri | |
| CY2007006I1 (el) | Αναστολεις συνθεσης απολιποπρωτεινης-β | |
| KR970001314A (ko) | 신규한 포름아미딘 화합물 | |
| KR960015946U (ko) | 레이져 트리머의 양면 부품용 척 | |
| DK0851865T3 (da) | Hidtil ukendte heterocykliske forbindelser | |
| KR960005897U (ko) | 측량용자 고정대 | |
| UA852S (uk) | Набір ваз | |
| ITRC940003A0 (it) | Campanello per appuntamenti | |
| SE9400968D0 (sv) | Heterocyclic compounds |