DK1012323T3 - Fremgangsmåde til produktion af dicarboxylsyrer - Google Patents

Fremgangsmåde til produktion af dicarboxylsyrer

Info

Publication number
DK1012323T3
DK1012323T3 DK98903871T DK98903871T DK1012323T3 DK 1012323 T3 DK1012323 T3 DK 1012323T3 DK 98903871 T DK98903871 T DK 98903871T DK 98903871 T DK98903871 T DK 98903871T DK 1012323 T3 DK1012323 T3 DK 1012323T3
Authority
DK
Denmark
Prior art keywords
organism
carbon source
maintain
medium
atmosphere
Prior art date
Application number
DK98903871T
Other languages
English (en)
Inventor
Nhuan Phu Nghiem
Mark Donnelly
Cynthia S Millard
Lucy Stols
Original Assignee
Ut Battelle Llc
Uchicago Argonne Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ut Battelle Llc, Uchicago Argonne Llc filed Critical Ut Battelle Llc
Application granted granted Critical
Publication of DK1012323T3 publication Critical patent/DK1012323T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44Polycarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44Polycarboxylic acids
    • C12P7/46Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185Escherichia
    • C12R2001/19Escherichia coli
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/848Escherichia
    • Y10S435/849Escherichia coli
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/853Lactobacillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK98903871T 1997-01-31 1998-01-30 Fremgangsmåde til produktion af dicarboxylsyrer DK1012323T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/792,655 US5869301A (en) 1995-11-02 1997-01-31 Method for the production of dicarboxylic acids
PCT/US1998/001877 WO1998033930A1 (en) 1997-01-31 1998-01-30 A method for the production of dicarboxylic acids

Publications (1)

Publication Number Publication Date
DK1012323T3 true DK1012323T3 (da) 2007-06-18

Family

ID=25157624

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98903871T DK1012323T3 (da) 1997-01-31 1998-01-30 Fremgangsmåde til produktion af dicarboxylsyrer

Country Status (14)

Country Link
US (1) US5869301A (da)
EP (1) EP1012323B1 (da)
JP (1) JP3681404B2 (da)
CN (1) CN1121500C (da)
AT (1) ATE360084T1 (da)
AU (1) AU724274B2 (da)
BR (1) BR9806822B1 (da)
CA (1) CA2278892C (da)
DE (1) DE69837607T2 (da)
DK (1) DK1012323T3 (da)
ES (1) ES2285757T3 (da)
HU (1) HU227509B1 (da)
PT (1) PT1012323E (da)
WO (1) WO1998033930A1 (da)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10129711B4 (de) * 2001-06-22 2007-08-23 Forschungszentrum Jülich GmbH Verfahren zur fermentativen Herstellung von Pyruvat
WO2004108069A2 (en) 2002-05-04 2004-12-16 Acorda Therapeutics, Inc. Compositions and methods for promoting neuronal outgrowth
DE10220234B4 (de) * 2002-05-06 2013-05-23 Forschungszentrum Jülich GmbH Verfahren sowie Mikroorganismen zur mikrobiellen Herstellung von Pyruvat aus Kohlenhydraten sowie Alkoholen
AU2003265561A1 (en) * 2002-08-15 2004-03-03 Acorda Therapeutics, Inc. Chimeric protein
AU2004241088B2 (en) * 2003-05-16 2010-08-05 Acorda Therapeutics, Inc. Compositions and methods for the treatment of CNS injuries
EP3211084B1 (en) 2003-05-16 2019-03-27 Acorda Therapeutics, Inc. Proteoglycan degrading mutants for treatment of cns
US7959914B2 (en) * 2003-05-16 2011-06-14 Acorda Therapeutics, Inc. Methods of reducing extravasation of inflammatory cells
JP4469568B2 (ja) * 2003-07-09 2010-05-26 三菱化学株式会社 有機酸の製造方法
WO2005010182A1 (ja) * 2003-07-29 2005-02-03 Research Institute Of Innovative Technology For The Earth コリネ型細菌形質転換体及びそれを用いるジカルボン酸の製造方法
CN100575496C (zh) * 2003-08-28 2009-12-30 三菱化学株式会社 产生琥珀酸的方法
EP1672067B1 (en) * 2003-09-17 2015-11-11 Mitsubishi Chemical Corporation Process for producing non-amino organic acid
CN100534972C (zh) * 2003-09-30 2009-09-02 味之素株式会社 从发酵液中纯化琥珀酸的方法
WO2005045049A1 (ja) * 2003-11-07 2005-05-19 Mitsubishi Chemical Corporation 有機酸アンモニウム溶液の製造方法
JP2005295998A (ja) * 2003-11-07 2005-10-27 Mitsubishi Chemicals Corp 有機酸アンモニウム溶液の製造方法
CA2566731C (en) * 2004-05-18 2012-07-24 Acorda Therapeutics, Inc. Methods of purifying chondroitinase and stable formulations thereof
EP1748062B1 (en) * 2004-05-20 2012-06-13 Ajinomoto Co., Inc. Succinic acid-producing bacterium and process for producing succinic acid
EP1760143B1 (en) * 2004-05-20 2012-05-16 Ajinomoto Co., Inc. Succinic acid-producing bacterium and process for producing succinic acid
BRPI0514734B1 (pt) * 2004-08-27 2018-02-06 Rice University VARIEDADE BACTERIANA DE E. Coli MODIFICADA
KR20070065870A (ko) * 2004-09-17 2007-06-25 라이스 유니버시티 다량의 숙신산염을 생산하는 세균
JP4537862B2 (ja) * 2005-01-18 2010-09-08 財団法人地球環境産業技術研究機構 好気性細菌による高効率な有機酸の製造方法
JP4380654B2 (ja) * 2005-04-22 2009-12-09 三菱化学株式会社 ポリエステル及びその製造方法
EP2366727A3 (en) * 2005-04-22 2015-05-06 Mitsubishi Chemical Corporation Biomass-resource-derived polyester and production process thereof
JP4380653B2 (ja) * 2005-04-22 2009-12-09 三菱化学株式会社 ポリエステル及びその製造方法
AU2006287257A1 (en) * 2005-09-09 2007-03-15 Genomatica, Inc. Methods and organisms for the growth-coupled production of succinate
CA2623635C (en) * 2005-09-26 2013-04-02 Acorda Therapeutics, Inc. Compositions and methods of using chondroitinase abci mutants
CN101297043B (zh) * 2005-10-18 2013-01-16 味之素株式会社 用于产生琥珀酸的方法
US7335066B2 (en) * 2005-12-16 2008-02-26 James A. Carroll Network connector and connection system
EP1995308B1 (en) * 2006-02-24 2014-07-30 Mitsubishi Chemical Corporation Bacterium capable of producing organic acid, and method for production of organic acid
EP1842843A1 (de) * 2006-04-04 2007-10-10 Basf Aktiengesellschaft Verfahren zur Herstellung eines Carbonsäurealkylesters
US8318453B2 (en) 2006-07-21 2012-11-27 Xyleco, Inc. Conversion systems for biomass
US7722864B2 (en) 2006-10-10 2010-05-25 Acorda Therapeutics, Inc. Compositions and methods of using chondroitinase ABCI mutants
WO2008091627A2 (en) * 2007-01-22 2008-07-31 Genomatica, Inc. Methods and organisms for growth-coupled production of 3-hydroxypropionic acid
EP3214179B1 (en) 2007-03-16 2021-03-03 Genomatica, Inc. Compositions and methods for the biosynthesis of 1,4-butanediol and its precursors
CN104694449B (zh) * 2007-03-20 2018-05-22 佛罗里达大学研究基金公司 用于有效生产琥珀酸和苹果酸的材料和方法
DE102007019184A1 (de) 2007-04-20 2008-10-23 Organo Balance Gmbh Mikroorganismus zur Herstellung von Bernsteinsäure
CA2899225A1 (en) 2007-07-06 2009-01-15 Basf Se Method for the production of an aqueous glucose solution
EP2543657A3 (en) * 2007-08-10 2013-08-14 Genomatica, Inc. Methods for the synthesis of acrylic acid and derivatives from fumaric acid
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
CN101896606B (zh) * 2007-11-20 2016-12-21 帝斯曼知识产权资产管理有限公司 在重组酵母中生产二羧酸
FR2925068B1 (fr) * 2007-12-13 2010-01-08 Roquette Freres Procedes de production d'acide succinique
BRPI0722315A2 (pt) * 2007-12-28 2014-06-10 Roquette Freres Método de cultura microbiana em larga escala
EP2245137B1 (en) 2008-01-22 2017-08-16 Genomatica, Inc. Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol
EP2262901B1 (en) 2008-03-05 2018-11-21 Genomatica, Inc. Primary alcohol producing organisms
CN103555643B (zh) * 2008-03-27 2016-08-10 基因组股份公司 用于产生己二酸和其他化合物的微生物
JP2011519561A (ja) 2008-05-01 2011-07-14 ジェノマティカ, インコーポレイテッド メタクリル酸の産生のための微生物
BRPI0913901A2 (pt) * 2008-06-17 2016-12-13 Genomatica Inc micro-organismos e métodos para a biossíntese de fumarato, malato e acrilato
CN107267562A (zh) 2008-07-08 2017-10-20 帝斯曼知识产权资产管理有限公司 通过在低pH下发酵生产二羧酸
US20100021978A1 (en) * 2008-07-23 2010-01-28 Genomatica, Inc. Methods and organisms for production of 3-hydroxypropionic acid
EP3514242A3 (en) 2008-09-10 2019-08-28 Genomatica, Inc. Microrganisms for the production of 1,4-butanediol
DE102008051727A1 (de) 2008-10-17 2010-04-22 Organo Balance Gmbh Mikroorganismus zur Herstellung von Bernsteinsäure
US20100184173A1 (en) * 2008-11-14 2010-07-22 Genomatica, Inc. Microorganisms for the production of methyl ethyl ketone and 2-butanol
CN102307986A (zh) * 2008-12-16 2012-01-04 基因组股份公司 用于将合成气和其他碳源转化成有用产品的微生物和方法
FR2941959B1 (fr) * 2009-02-12 2013-06-07 Roquette Freres Procedes de production d'acide succinique
KR101711308B1 (ko) 2009-04-02 2017-02-28 유니버시티 오브 플로리다 리서치 파운데이션, 인크. 석시네이트 생성을 위한 경로의 엔지니어링
KR20120068763A (ko) 2009-04-30 2012-06-27 게노마티카 인코포레이티드 아이소프로판올, n-부탄올 및 아이소부탄올 생산 유기체
CA2759994C (en) * 2009-04-30 2019-06-11 Genomatica, Inc. Organisms for the production of 1,3-butanediol
EP4273255A3 (en) 2009-05-07 2024-01-03 Genomatica, Inc. Microorganisms and methods for the biosynthesis of hexamethylenediamine
EP2429587A4 (en) * 2009-05-15 2014-10-08 Genomatica Inc ORGANISMS FOR THE PREPARATION OF CYCLOHEXANONE
EP3199511B1 (en) * 2009-06-04 2020-01-29 Genomatica, Inc. Process of separating components of a fermentation broth
WO2010141920A2 (en) 2009-06-04 2010-12-09 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol and related methods
EP2440669A4 (en) * 2009-06-10 2013-08-28 Genomatica Inc MICROOGANISMS AND PROCEDURES FOR THE CARBON EFFECTIVE BIOSYNTHESIS MEK AND 2-BUTANOL
DK2462221T3 (da) 2009-08-05 2017-05-22 Genomatica Inc Semisyntetisk terephthalsyre via mikroorganismer der producerer muconsyre
WO2011023700A2 (en) * 2009-08-27 2011-03-03 Dsm Ip Assets B.V. Dicarboxylic acid fermentation process
US8715971B2 (en) 2009-09-09 2014-05-06 Genomatica, Inc. Microorganisms and methods for the co-production of isopropanol and 1,4-butanediol
CN105441374A (zh) * 2009-10-13 2016-03-30 基因组股份公司 生产1,4-丁二醇、4-羟基丁醛、4-羟基丁酰-coa、腐胺和相关化合物的微生物及其相关方法
KR20180014240A (ko) 2009-10-23 2018-02-07 게노마티카 인코포레이티드 아닐린의 제조를 위한 미생물
US8530210B2 (en) 2009-11-25 2013-09-10 Genomatica, Inc. Microorganisms and methods for the coproduction 1,4-butanediol and gamma-butyrolactone
CA2783096A1 (en) 2009-12-10 2011-06-16 Genomatica, Inc. Methods and organisms for converting synthesis gas or other gaseous carbon sources and methanol to 1,3-butanediol
CA2787314A1 (en) 2010-01-29 2011-08-04 Genomatica, Inc. Microorganisms and methods for the biosynthesis of p-toluate and terephthalate
US8048661B2 (en) * 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
US8445244B2 (en) * 2010-02-23 2013-05-21 Genomatica, Inc. Methods for increasing product yields
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
US8580543B2 (en) 2010-05-05 2013-11-12 Genomatica, Inc. Microorganisms and methods for the biosynthesis of butadiene
US20110306734A1 (en) 2010-06-02 2011-12-15 Bayer Materialscience Ag Thermoplastically processable polyurethanes based on succinic acid propionates
PL2580296T3 (pl) * 2010-06-08 2016-08-31 Univ Oregon State Kleje samoprzylepne na bazie oleju roślinnego
JP2013535203A (ja) 2010-07-26 2013-09-12 ジェノマティカ・インコーポレイテッド 芳香族、2,4−ペンタジエノエートおよび1,3−ブタジエンを生合成するための微生物および方法
WO2012125218A1 (en) 2011-03-14 2012-09-20 Dow Global Technologies Llc Processes for producing terephthalic acid and terephthalic esters
CN102242074B (zh) * 2011-04-12 2014-08-06 叶春 一种兼性厌氧菌的筛选方法
US8580096B2 (en) 2011-09-29 2013-11-12 Uchicago Argonne, Llc Bioprocess utilizing carbon dioxide and electrodeionization
BR112014007306A2 (pt) 2011-09-30 2017-04-04 Bayer Ip Gmbh artigos extrudados homogêneos feitos a partir de poliuretanos termoplasticamente processáveis com base em poliéster-dióis formados a partir de ácido succínico e de 1,3-propanodiol
AU2012376541B2 (en) 2012-04-09 2016-05-12 Avery Dennison Corporation Pressure sensitive adhesives based on renewable resources, UV curing and related methods
WO2013166075A1 (en) 2012-04-30 2013-11-07 Woods Hole Oceanographic Institution Cobalamin acquisition protein and use thereof
CN104685058B (zh) 2012-06-04 2020-07-07 基因组股份公司 制造4-羟基丁酸酯、1,4-丁二醇和相关化合物的微生物和方法
US10920251B2 (en) * 2016-05-05 2021-02-16 William Marsh Rice University Microbial production of fats
CN110951660B (zh) * 2019-12-19 2021-12-03 江南大学 一株固定co2产苹果酸的大肠杆菌工程菌的构建及应用
CN114350718B (zh) * 2021-12-31 2024-06-07 安徽丰原发酵技术工程研究有限公司 一种发酵生产苹果酸的方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5543759B2 (da) * 1972-06-28 1980-11-07
US4190495A (en) * 1976-09-27 1980-02-26 Research Corporation Modified microorganisms and method of preparing and using same
JPS60114197A (ja) * 1983-11-25 1985-06-20 Agency Of Ind Science & Technol 微生物によるジカルボン酸の製造法
US4871667A (en) * 1984-11-26 1989-10-03 Agency Of Industrial Science & Technology Process for preparing muconic acid
US5168055A (en) * 1986-06-11 1992-12-01 Rathin Datta Fermentation and purification process for succinic acid
DE3783081T2 (de) * 1986-06-11 1993-04-15 Michigan Biotech Inst Verfahren zur herstellung von bernsteinsaeure durch anaerobe fermentation.
US5143834A (en) * 1986-06-11 1992-09-01 Glassner David A Process for the production and purification of succinic acid
US5182199A (en) * 1987-05-27 1993-01-26 Hartley Brian S Thermophilic ethanol production in a two-stage closed system
DE69020555T2 (de) * 1989-04-27 1995-11-02 Biocontrol Systems Inc Fällungstest für mikroorganismen.
US5416020A (en) * 1992-09-29 1995-05-16 Bio-Technical Resources Lactobacillus delbrueckii ssp. bulgaricus strain and fermentation process for producing L-(+)-lactic acid
FR2702492B1 (fr) * 1993-03-12 1995-05-24 Rhone Poulenc Chimie Procédé de production par fermentation d'acide itaconique.
NZ267894A (en) * 1993-06-25 1997-10-24 Du Pont Enzymatic preparation of pyruvic acid
CN1130404A (zh) * 1993-07-01 1996-09-04 纳幕尔杜邦公司 一种利用微生物双转化株制备二羟乙酸/氨甲基膦酸混合物改进方法
US5521075A (en) * 1994-12-19 1996-05-28 Michigan Biotechnology Institute Method for making succinic acid, anaerobiospirillum succiniciproducens variants for use in process and methods for obtaining variants
US5504004A (en) * 1994-12-20 1996-04-02 Michigan Biotechnology Institute Process for making succinic acid, microorganisms for use in the process and methods of obtaining the microorganisms

Also Published As

Publication number Publication date
CN1246155A (zh) 2000-03-01
DE69837607T2 (de) 2007-12-27
CA2278892A1 (en) 1998-08-06
BR9806822A (pt) 2000-05-09
US5869301A (en) 1999-02-09
AU724274B2 (en) 2000-09-14
WO1998033930A1 (en) 1998-08-06
HUP0001997A2 (hu) 2000-10-28
EP1012323A4 (en) 2002-01-16
AU6052398A (en) 1998-08-25
DE69837607D1 (de) 2007-05-31
JP3681404B2 (ja) 2005-08-10
ES2285757T3 (es) 2007-11-16
CN1121500C (zh) 2003-09-17
ATE360084T1 (de) 2007-05-15
EP1012323B1 (en) 2007-04-18
EP1012323A1 (en) 2000-06-28
HUP0001997A3 (en) 2002-01-28
HU227509B1 (en) 2011-07-28
BR9806822B1 (pt) 2009-05-05
CA2278892C (en) 2009-02-24
JP2000515389A (ja) 2000-11-21
PT1012323E (pt) 2007-05-31

Similar Documents

Publication Publication Date Title
DK1012323T3 (da) Fremgangsmåde til produktion af dicarboxylsyrer
CA2236472A1 (en) A mutant e. coli strain with increased succinic acid production
MX9708687A (es) Bioconversion de una fuente de carbono fermentable a 1,3-propanodiol por un solo microorganismo.
DE69429452D1 (de) Herstellungsverfahren einer substanz
Karube et al. Methane production from wastewaters by immobilized methanogenic bacteria
ATE196776T1 (de) Neue mikroorganismen, deren verwendung und verfahren zur herstellung von l-alpha-aminosäuren
ATE332389T1 (de) Verbessertes fermentationsverfahren
MY111441A (en) Method of producing l-glutamic acid by fermentation
KR850004267A (ko) 폴리-d-(-)-3-하이드록시부티르산의 제조방법
DK0765938T3 (da) Produktion af vitamin B6 ved fermentering
JPS5743685A (en) L-glutamic oxidase
DE3752177D1 (de) Vorrichtung zur Kultivierung von Mikroorganismen
KR850001802A (ko) 박테리아에서 l-아미노산을 제조하는 방법
ATE355386T1 (de) Verfahren zur herstellung von l-glutaminsäure durch kontinuierliche gärung
JPS6384495A (ja) 酢酸の製造方法
JPS61124374A (ja) 酢酸からメタンを生成する微生物の培養法
JPS6423894A (en) Production of adipic acid
JPS58158188A (ja) D−β−ヒドロキシイソ酪酸の製造法
JPS642592A (en) Production of pyrroloquinolinequinone
FR2364184A1 (fr) Procede de purification d'eaux usees ayant une teneur elevee en substances organiques
McCann Method of producing methane from organic waste
ES8602943A1 (es) Procedimiento para la mejora de la fermentacion de acido clavulanico y sus sales
KR900009967A (ko) 글루타민산을 생산하는 미생물 및 이를 이용한 글루타민산의 제조방법
KR960009065B1 (en) Preparation process of poly-3-hydroxybutyrate
RU95102952A (ru) Способ направленного биосинтеза лимонной кислоты