ES8602943A1 - Procedimiento para la mejora de la fermentacion de acido clavulanico y sus sales - Google Patents
Procedimiento para la mejora de la fermentacion de acido clavulanico y sus salesInfo
- Publication number
- ES8602943A1 ES8602943A1 ES537157A ES537157A ES8602943A1 ES 8602943 A1 ES8602943 A1 ES 8602943A1 ES 537157 A ES537157 A ES 537157A ES 537157 A ES537157 A ES 537157A ES 8602943 A1 ES8602943 A1 ES 8602943A1
- Authority
- ES
- Spain
- Prior art keywords
- clavulanic acid
- biological cultivation
- carbon source
- acid prod
- prod
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
PROCEDIMIENTO PARA OBTENER ACIDO CLAVULANICO O SUS SALES MEDIANTE CULTIVO BIOLOGICO. EL PROCEDIMIENTO CONSISTE EN CULTIVAR UN MICROORGANISMO PRODUCTOR DE ACIDO CLAVULANICO DE FORMULA (I), COMO CEPAS DE STREPTOMYCES, EN UN TANQUE PARA FERMENTACION AEROBIA, CON AGITACION Y AIREACION, A TEMPERATURA ENTRE 26 Y 28C EN UN MEDIO QUE CONTIENE NITROGENO ASIMILABLE, SALES MINERALES Y ANTIESPUMANTES SIN FUENTE DE CARBONO O 0,5% COMO MAXIMO EN LA ETAPA INICIAL, PARA IRSE AÑADIENDO LA FUENTE DE CARBONO A LO LARGO DE LA FERMENTACION DE FORMA CONTINUA O INTERMITENTE A INTERVALOS COMPRENDIDOS ENTRE 1 MINUTO Y 6 HORAS Y A CONCENTRACIONES DIARIAS ENTRE 0,25 Y 1,25%.
Priority Applications (18)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES537157A ES8602943A1 (es) | 1984-10-27 | 1984-10-27 | Procedimiento para la mejora de la fermentacion de acido clavulanico y sus sales |
NZ213963A NZ213963A (en) | 1984-10-27 | 1985-10-25 | Production of clavulanic acid |
AR85302065A AR245221A1 (es) | 1984-10-27 | 1985-10-25 | Un metodo para la produccion de acido clavulanico por fermentacion de s. clavuligerus |
ZA858211A ZA858211B (en) | 1984-10-27 | 1985-10-25 | Preparation of clavulanic acid and its salts and esters |
MX8544U MX7417E (es) | 1984-10-27 | 1985-10-25 | Metodo para la preparacion de acido clavulanico y sus derivados |
AU49090/85A AU600655B2 (en) | 1984-10-27 | 1985-10-25 | Preparation of clavulanic acid and its salts and esters |
CN85108444A CN1010415B (zh) | 1984-10-27 | 1985-10-26 | 棒酸及其盐和酯的制备方法 |
EG681/85A EG17153A (en) | 1984-10-27 | 1985-10-27 | Preparation of clavulanic acid and its salts and esters |
DE8585307783T DE3583281D1 (de) | 1984-10-27 | 1985-10-28 | Herstellung von clavulansaeure und ihren salzen und estern. |
EP88115979A EP0312813A3 (en) | 1984-10-27 | 1985-10-28 | Preparation of clavulanic acid and its salts and esters |
JP60242586A JPH0646949B2 (ja) | 1984-10-27 | 1985-10-28 | クラブラン酸の製法 |
AT85307783T ATE64621T1 (de) | 1984-10-27 | 1985-10-28 | Herstellung von clavulansaeure und ihren salzen und estern. |
CA000494016A CA1307223C (en) | 1984-10-27 | 1985-10-28 | Preparation of clavulanic acid and its salts and esters |
EP85307783A EP0182522B1 (en) | 1984-10-27 | 1985-10-28 | Preparation of clavulanic acid and its salts and esters |
IN855/MAS/85A IN162768B (es) | 1984-10-27 | 1985-10-28 | |
IE269985A IE58365B1 (en) | 1984-10-27 | 1985-11-01 | Preparation of clavulanic acid and its salts and esters |
IN940/MAS/87A IN166818B (es) | 1984-10-27 | 1987-12-29 | |
HK26696A HK26696A (en) | 1984-10-27 | 1996-02-08 | Preparation of clavulanic acid and its salts and esters |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES537157A ES8602943A1 (es) | 1984-10-27 | 1984-10-27 | Procedimiento para la mejora de la fermentacion de acido clavulanico y sus sales |
Publications (2)
Publication Number | Publication Date |
---|---|
ES537157A0 ES537157A0 (es) | 1985-12-16 |
ES8602943A1 true ES8602943A1 (es) | 1985-12-16 |
Family
ID=8488053
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES537157A Expired ES8602943A1 (es) | 1984-10-27 | 1984-10-27 | Procedimiento para la mejora de la fermentacion de acido clavulanico y sus sales |
Country Status (2)
Country | Link |
---|---|
ES (1) | ES8602943A1 (es) |
ZA (1) | ZA858211B (es) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997019187A1 (es) * | 1995-11-23 | 1997-05-29 | Antibioticos, S.A. | Procedimiento de produccion de acido clavulanico y/o sus sales |
-
1984
- 1984-10-27 ES ES537157A patent/ES8602943A1/es not_active Expired
-
1985
- 1985-10-25 ZA ZA858211A patent/ZA858211B/xx unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997019187A1 (es) * | 1995-11-23 | 1997-05-29 | Antibioticos, S.A. | Procedimiento de produccion de acido clavulanico y/o sus sales |
ES2101658A1 (es) * | 1995-11-23 | 1997-07-01 | Antibioticos Sa | Nuevo procedimiento de produccion de acido clavulanico y sus sales. |
Also Published As
Publication number | Publication date |
---|---|
ES537157A0 (es) | 1985-12-16 |
ZA858211B (en) | 1986-08-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20050917 |