DK0989112T3 - Mellemprodukter til fremstilling af guanidinomethylcyclohexancarboxylsyreesterderivater - Google Patents

Mellemprodukter til fremstilling af guanidinomethylcyclohexancarboxylsyreesterderivater

Info

Publication number
DK0989112T3
DK0989112T3 DK99124756T DK99124756T DK0989112T3 DK 0989112 T3 DK0989112 T3 DK 0989112T3 DK 99124756 T DK99124756 T DK 99124756T DK 99124756 T DK99124756 T DK 99124756T DK 0989112 T3 DK0989112 T3 DK 0989112T3
Authority
DK
Denmark
Prior art keywords
intermediates
preparation
carboxylic acid
acid ester
ester derivatives
Prior art date
Application number
DK99124756T
Other languages
Danish (da)
English (en)
Inventor
Osamu Komoda
Hiromichi Fujiwara
Toshiharu Yanagi
Original Assignee
Nagase Chemtex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nagase Chemtex Corp filed Critical Nagase Chemtex Corp
Application granted granted Critical
Publication of DK0989112T3 publication Critical patent/DK0989112T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/94—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DK99124756T 1994-08-30 1995-08-30 Mellemprodukter til fremstilling af guanidinomethylcyclohexancarboxylsyreesterderivater DK0989112T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP24348994 1994-08-30
JP24349094 1994-08-30
JP24827094 1994-09-05
JP25265594 1994-09-09
EP95930012A EP0775692B1 (en) 1994-08-30 1995-08-30 Guanidinomethyl cyclohexane carboxylic ester derivative

Publications (1)

Publication Number Publication Date
DK0989112T3 true DK0989112T3 (da) 2004-07-12

Family

ID=27477919

Family Applications (3)

Application Number Title Priority Date Filing Date
DK99124756T DK0989112T3 (da) 1994-08-30 1995-08-30 Mellemprodukter til fremstilling af guanidinomethylcyclohexancarboxylsyreesterderivater
DK95930012T DK0775692T3 (da) 1994-08-30 1995-08-30 Guanidinomethylcyclohexancarboxylsyreesterderivater
DK04003617T DK1449828T3 (da) 1994-08-30 1995-08-30 Mellemprodukter til fremstilling af guanidinomethylcyclohexancarboxylsyreesterderivater

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK95930012T DK0775692T3 (da) 1994-08-30 1995-08-30 Guanidinomethylcyclohexancarboxylsyreesterderivater
DK04003617T DK1449828T3 (da) 1994-08-30 1995-08-30 Mellemprodukter til fremstilling af guanidinomethylcyclohexancarboxylsyreesterderivater

Country Status (13)

Country Link
US (3) US6284791B1 (ja)
EP (3) EP0775692B1 (ja)
JP (1) JP3739011B2 (ja)
KR (2) KR100416066B1 (ja)
AT (3) ATE359997T1 (ja)
DE (3) DE69519581T2 (ja)
DK (3) DK0989112T3 (ja)
ES (3) ES2285288T3 (ja)
GR (1) GR3035289T3 (ja)
HK (1) HK1027092A1 (ja)
PT (3) PT775692E (ja)
TW (1) TW408103B (ja)
WO (1) WO1996006825A1 (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3468244B2 (ja) * 1995-12-22 2003-11-17 ナガセケムテックス株式会社 抗ヘリコバクターピロリ剤
CN1203055C (zh) * 2001-09-26 2005-05-25 朱德煦 治疗或预防细菌感染的方法和组合物
MX2008011594A (es) 2006-03-10 2008-09-22 Arigen Pharmaceuticals Inc Derivado de piridina novedoso que tiene actividad anti-helicobacter pylori.
CN102378761A (zh) 2009-04-09 2012-03-14 阿利健制药有限公司 吡啶硫基衍生物以及含有该衍生物的具有抗幽门螺杆菌作用的医药组合物

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US2092725A (en) * 1936-10-15 1937-09-07 Dow Chemical Co Alkyl-bromo-hydroxy-diphenyls
BE509380A (ja) * 1950-02-23
JPS5692260A (en) 1979-12-26 1981-07-25 Nippon Chemiphar Co Ltd Cyclohexanecarboxylic ester and its preparation
JPS5692261A (en) 1979-12-26 1981-07-25 Nippon Chemiphar Co Ltd Novel cyclohexanecarboxylic derivative and its preparation
AU541738B2 (en) 1979-09-20 1985-01-17 Nippon Chemiphar Co. Ltd. Cyclohexane carboxylic acid derivatives
JPS5645454A (en) 1979-09-20 1981-04-25 Nippon Chemiphar Co Ltd Cyclohexanecarboxylic acid derivative and its preparation
JPS5716855A (en) 1980-07-04 1982-01-28 Teikoku Chem Ind Corp Ltd 4-guanidinomethylcyclohexanecarboxylic acid ester and its preparation
JPS5716856A (en) * 1980-07-04 1982-01-28 Teikoku Chem Ind Corp Ltd 4-guanidinomethylcyclohexanecarboxylic acid ester and its preparation
JPS5721360A (en) 1980-07-14 1982-02-04 Teikoku Chem Ind Corp Ltd Allyl 4-guanidinomethylcyclohexanecarboxylate and its preparation
JPS5735556A (en) 1980-08-08 1982-02-26 Nippon Chemiphar Co Ltd Preparation of guanidinomethylcyclohexanecarboxylic acid ester
JPS5748959A (en) 1980-09-08 1982-03-20 Nippon Chemiphar Co Ltd Preparation of cyclohexanecarboxylic acid derivative or its salt
JPS5748958A (en) 1980-09-08 1982-03-20 Nippon Chemiphar Co Ltd Cyclohexanecarboxylic acid esters and their acid addition salts
JPS5748960A (en) 1980-09-08 1982-03-20 Nippon Chemiphar Co Ltd Novel cyclohexanecarboxylic acid derivative and its preparation
JPS5775921A (en) 1980-10-29 1982-05-12 Nippon Chemiphar Co Ltd Noval remedy for peptic ulcer
JPS5775922A (en) 1980-10-29 1982-05-12 Nippon Chemiphar Co Ltd Novel remedy for peptic ulcer
JPS5775920A (en) 1980-10-29 1982-05-12 Nippon Chemiphar Co Ltd Noval remedy for peptic ulcer
JPS57126463A (en) 1981-01-29 1982-08-06 Nippon Chemiphar Co Ltd Novel carboxylic ester and its preparation
JPS57122060A (en) 1981-01-22 1982-07-29 Nippon Chemiphar Co Ltd Carboxylic acid ester and its preparation
JPS57122062A (en) 1981-01-22 1982-07-29 Nippon Chemiphar Co Ltd Novel trans-4-guanidinocyclohexanecarboxylic acid derivative and its preparation
JPS57126462A (en) 1981-01-29 1982-08-06 Nippon Chemiphar Co Ltd Novel carboxylic ester and its preparation
JPS57122059A (en) 1981-01-22 1982-07-29 Nippon Chemiphar Co Ltd Novel cyclohexanecarboxylic acid derivative and its preparation
JPS57122061A (en) 1981-01-22 1982-07-29 Nippon Chemiphar Co Ltd Novel cyclohexanecarboxylic acid derivative and its preparation
US4465851A (en) 1981-01-22 1984-08-14 Nippon Chemiphar Co., Ltd. Guanidinocyclohexanecarboxylic acid derivatives
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JPS57197256A (en) 1981-05-28 1982-12-03 Nippon Chemiphar Co Ltd Novel cyclohexanecarboxamide derivative and its preparation
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JP3073006B2 (ja) 1990-11-28 2000-08-07 株式会社日立製作所 聴覚機能補助装置
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JP3150780B2 (ja) 1992-09-01 2001-03-26 株式会社資生堂 皮膚外用剤
JP3150781B2 (ja) 1992-09-01 2001-03-26 株式会社資生堂 皮膚外用剤
JP3150782B2 (ja) 1992-09-01 2001-03-26 株式会社資生堂 皮膚外用剤
JP3046288B1 (ja) 1998-12-28 2000-05-29 京セラ株式会社 半導体・液晶製造装置用部材
JP3555682B2 (ja) 2002-07-09 2004-08-18 セイコーエプソン株式会社 液体吐出ヘッド

Also Published As

Publication number Publication date
ATE359997T1 (de) 2007-05-15
DE69532897D1 (de) 2004-05-19
EP0989112B1 (en) 2004-04-14
PT775692E (pt) 2001-05-31
KR100404714B1 (ko) 2004-05-31
KR970705540A (ko) 1997-10-09
KR100416066B1 (ko) 2004-01-24
ATE197950T1 (de) 2000-12-15
US6960681B2 (en) 2005-11-01
TW408103B (en) 2000-10-11
ES2285288T3 (es) 2007-11-16
DE69519581D1 (de) 2001-01-11
JP3739011B2 (ja) 2006-01-25
DE69532897T2 (de) 2005-04-21
DE69535475D1 (de) 2007-05-31
EP0775692B1 (en) 2000-12-06
ATE264291T1 (de) 2004-04-15
DK1449828T3 (da) 2007-08-06
ES2153902T3 (es) 2001-03-16
US20050075402A1 (en) 2005-04-07
EP0775692A4 (en) 1997-12-17
GR3035289T3 (en) 2001-04-30
HK1027092A1 (en) 2003-09-17
DE69535475T2 (de) 2008-01-03
EP1449828A2 (en) 2004-08-25
PT989112E (pt) 2004-08-31
PT1449828E (pt) 2007-06-01
EP1449828B1 (en) 2007-04-18
US6831190B1 (en) 2004-12-14
ES2214802T3 (es) 2004-09-16
EP0775692A1 (en) 1997-05-28
US6284791B1 (en) 2001-09-04
WO1996006825A1 (fr) 1996-03-07
EP1449828A3 (en) 2004-12-22
DE69519581T2 (de) 2001-05-31
DK0775692T3 (da) 2001-03-05
EP0989112A3 (en) 2000-11-15
EP0989112A2 (en) 2000-03-29

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