DK0775692T3 - Guanidinomethylcyclohexancarboxylsyreesterderivater - Google Patents

Guanidinomethylcyclohexancarboxylsyreesterderivater

Info

Publication number
DK0775692T3
DK0775692T3 DK95930012T DK95930012T DK0775692T3 DK 0775692 T3 DK0775692 T3 DK 0775692T3 DK 95930012 T DK95930012 T DK 95930012T DK 95930012 T DK95930012 T DK 95930012T DK 0775692 T3 DK0775692 T3 DK 0775692T3
Authority
DK
Denmark
Prior art keywords
acid ester
ester derivatives
guanidinomethylcyclohexanecarboxylic acid
present
helicobacter pylori
Prior art date
Application number
DK95930012T
Other languages
English (en)
Inventor
Osamu Kamoda
Hiromichi Fujiwara
Toshiharu Yanagi
Original Assignee
Teikoku Chem Ind Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teikoku Chem Ind Co Ltd filed Critical Teikoku Chem Ind Co Ltd
Application granted granted Critical
Publication of DK0775692T3 publication Critical patent/DK0775692T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/94—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DK95930012T 1994-08-30 1995-08-30 Guanidinomethylcyclohexancarboxylsyreesterderivater DK0775692T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP24348994 1994-08-30
JP24349094 1994-08-30
JP24827094 1994-09-05
JP25265594 1994-09-09
PCT/JP1995/001725 WO1996006825A1 (fr) 1994-08-30 1995-08-30 Derive ester de l'acide guanidinomethylcyclohexanecarboxylique

Publications (1)

Publication Number Publication Date
DK0775692T3 true DK0775692T3 (da) 2001-03-05

Family

ID=27477919

Family Applications (3)

Application Number Title Priority Date Filing Date
DK99124756T DK0989112T3 (da) 1994-08-30 1995-08-30 Mellemprodukter til fremstilling af guanidinomethylcyclohexancarboxylsyreesterderivater
DK04003617T DK1449828T3 (da) 1994-08-30 1995-08-30 Mellemprodukter til fremstilling af guanidinomethylcyclohexancarboxylsyreesterderivater
DK95930012T DK0775692T3 (da) 1994-08-30 1995-08-30 Guanidinomethylcyclohexancarboxylsyreesterderivater

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK99124756T DK0989112T3 (da) 1994-08-30 1995-08-30 Mellemprodukter til fremstilling af guanidinomethylcyclohexancarboxylsyreesterderivater
DK04003617T DK1449828T3 (da) 1994-08-30 1995-08-30 Mellemprodukter til fremstilling af guanidinomethylcyclohexancarboxylsyreesterderivater

Country Status (13)

Country Link
US (3) US6284791B1 (da)
EP (3) EP1449828B1 (da)
JP (1) JP3739011B2 (da)
KR (2) KR100416066B1 (da)
AT (3) ATE197950T1 (da)
DE (3) DE69519581T2 (da)
DK (3) DK0989112T3 (da)
ES (3) ES2214802T3 (da)
GR (1) GR3035289T3 (da)
HK (1) HK1027092A1 (da)
PT (3) PT1449828E (da)
TW (1) TW408103B (da)
WO (1) WO1996006825A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0870500B1 (en) * 1995-12-22 2008-02-20 Nagase ChemteX Corporation Anti-helicobacter pylori agent
CN1203055C (zh) * 2001-09-26 2005-05-25 朱德煦 治疗或预防细菌感染的方法和组合物
RU2433126C2 (ru) 2006-03-10 2011-11-10 Ариджен Фармасьютикалз, Инк. Новые производные пиридина, обладающие анти-helicobacter pylori активностью
EP2420500A4 (en) 2009-04-09 2012-09-05 Arigen Pharmaceuticals Inc PYRIDINTHIODERIVATE AND PHARMACEUTICAL COMPOSITION THEREOF AND WITH ANTI-HELIDOBACTER PYLORI EFFECT

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US2092725A (en) * 1936-10-15 1937-09-07 Dow Chemical Co Alkyl-bromo-hydroxy-diphenyls
BE509380A (da) * 1950-02-23
JPS5692261A (en) * 1979-12-26 1981-07-25 Nippon Chemiphar Co Ltd Novel cyclohexanecarboxylic derivative and its preparation
JPS5692260A (en) 1979-12-26 1981-07-25 Nippon Chemiphar Co Ltd Cyclohexanecarboxylic ester and its preparation
AU541738B2 (en) * 1979-09-20 1985-01-17 Nippon Chemiphar Co. Ltd. Cyclohexane carboxylic acid derivatives
JPS5645454A (en) * 1979-09-20 1981-04-25 Nippon Chemiphar Co Ltd Cyclohexanecarboxylic acid derivative and its preparation
JPS5716855A (en) * 1980-07-04 1982-01-28 Teikoku Chem Ind Corp Ltd 4-guanidinomethylcyclohexanecarboxylic acid ester and its preparation
JPS5716856A (en) * 1980-07-04 1982-01-28 Teikoku Chem Ind Corp Ltd 4-guanidinomethylcyclohexanecarboxylic acid ester and its preparation
JPS5721360A (en) 1980-07-14 1982-02-04 Teikoku Chem Ind Corp Ltd Allyl 4-guanidinomethylcyclohexanecarboxylate and its preparation
JPS5735556A (en) 1980-08-08 1982-02-26 Nippon Chemiphar Co Ltd Preparation of guanidinomethylcyclohexanecarboxylic acid ester
JPS5748958A (en) 1980-09-08 1982-03-20 Nippon Chemiphar Co Ltd Cyclohexanecarboxylic acid esters and their acid addition salts
JPS5748960A (en) 1980-09-08 1982-03-20 Nippon Chemiphar Co Ltd Novel cyclohexanecarboxylic acid derivative and its preparation
JPS5748959A (en) 1980-09-08 1982-03-20 Nippon Chemiphar Co Ltd Preparation of cyclohexanecarboxylic acid derivative or its salt
JPS5775922A (en) 1980-10-29 1982-05-12 Nippon Chemiphar Co Ltd Novel remedy for peptic ulcer
JPS5775920A (en) 1980-10-29 1982-05-12 Nippon Chemiphar Co Ltd Noval remedy for peptic ulcer
JPS5775921A (en) 1980-10-29 1982-05-12 Nippon Chemiphar Co Ltd Noval remedy for peptic ulcer
JPS57126462A (en) 1981-01-29 1982-08-06 Nippon Chemiphar Co Ltd Novel carboxylic ester and its preparation
US4465851A (en) 1981-01-22 1984-08-14 Nippon Chemiphar Co., Ltd. Guanidinocyclohexanecarboxylic acid derivatives
JPS57122061A (en) 1981-01-22 1982-07-29 Nippon Chemiphar Co Ltd Novel cyclohexanecarboxylic acid derivative and its preparation
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JPS57122062A (en) 1981-01-22 1982-07-29 Nippon Chemiphar Co Ltd Novel trans-4-guanidinocyclohexanecarboxylic acid derivative and its preparation
JPS57122059A (en) * 1981-01-22 1982-07-29 Nippon Chemiphar Co Ltd Novel cyclohexanecarboxylic acid derivative and its preparation
JPS57126463A (en) 1981-01-29 1982-08-06 Nippon Chemiphar Co Ltd Novel carboxylic ester and its preparation
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JPS57197256A (en) 1981-05-28 1982-12-03 Nippon Chemiphar Co Ltd Novel cyclohexanecarboxamide derivative and its preparation
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JPS6330462A (ja) 1986-07-24 1988-02-09 Taiyo Yakuhin Kogyo Kk 新規グアニジノメチルベンツアミド誘導体およびそれを有効成分とする抗潰瘍剤
EP0258898B1 (en) * 1986-09-04 1992-04-22 Idemitsu Kosan Company Limited Liquid-crystalline polymer
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JPH04217950A (ja) 1990-03-28 1992-08-07 Asahi Chem Ind Co Ltd ヒドロキサム酸誘導体および酵素阻害剤ならびに抗潰瘍剤
JP3073006B2 (ja) 1990-11-28 2000-08-07 株式会社日立製作所 聴覚機能補助装置
JP3150781B2 (ja) 1992-09-01 2001-03-26 株式会社資生堂 皮膚外用剤
DE69316681T2 (de) 1992-08-27 1998-05-14 Shiseido Co Ltd Äusserliche, auf der Haut anzuwendende Depigmentierungsmittel enthaltende Zusammensetzung
JP3150780B2 (ja) 1992-09-01 2001-03-26 株式会社資生堂 皮膚外用剤
JP3150782B2 (ja) 1992-09-01 2001-03-26 株式会社資生堂 皮膚外用剤
JP3046288B1 (ja) 1998-12-28 2000-05-29 京セラ株式会社 半導体・液晶製造装置用部材
JP3555682B2 (ja) 2002-07-09 2004-08-18 セイコーエプソン株式会社 液体吐出ヘッド

Also Published As

Publication number Publication date
US6831190B1 (en) 2004-12-14
EP0989112A2 (en) 2000-03-29
ATE264291T1 (de) 2004-04-15
EP1449828B1 (en) 2007-04-18
EP0775692B1 (en) 2000-12-06
EP1449828A2 (en) 2004-08-25
JP3739011B2 (ja) 2006-01-25
DE69535475D1 (de) 2007-05-31
EP0989112B1 (en) 2004-04-14
WO1996006825A1 (fr) 1996-03-07
EP0989112A3 (en) 2000-11-15
DK0989112T3 (da) 2004-07-12
HK1027092A1 (en) 2003-09-17
KR970705540A (ko) 1997-10-09
DE69535475T2 (de) 2008-01-03
ES2285288T3 (es) 2007-11-16
ES2153902T3 (es) 2001-03-16
DE69519581D1 (de) 2001-01-11
PT1449828E (pt) 2007-06-01
US6284791B1 (en) 2001-09-04
DK1449828T3 (da) 2007-08-06
ATE197950T1 (de) 2000-12-15
US6960681B2 (en) 2005-11-01
ATE359997T1 (de) 2007-05-15
KR100404714B1 (ko) 2004-05-31
EP0775692A1 (en) 1997-05-28
EP1449828A3 (en) 2004-12-22
DE69532897T2 (de) 2005-04-21
EP0775692A4 (en) 1997-12-17
PT775692E (pt) 2001-05-31
DE69519581T2 (de) 2001-05-31
US20050075402A1 (en) 2005-04-07
ES2214802T3 (es) 2004-09-16
KR100416066B1 (ko) 2004-01-24
PT989112E (pt) 2004-08-31
TW408103B (en) 2000-10-11
GR3035289T3 (en) 2001-04-30
DE69532897D1 (de) 2004-05-19

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