DK0948541T3 - Analoge af PTHrP - Google Patents

Analoge af PTHrP

Info

Publication number
DK0948541T3
DK0948541T3 DK97951595T DK97951595T DK0948541T3 DK 0948541 T3 DK0948541 T3 DK 0948541T3 DK 97951595 T DK97951595 T DK 97951595T DK 97951595 T DK97951595 T DK 97951595T DK 0948541 T3 DK0948541 T3 DK 0948541T3
Authority
DK
Denmark
Prior art keywords
pthrp
analogs
parathyroid hormone
pth
acc
Prior art date
Application number
DK97951595T
Other languages
Danish (da)
English (en)
Inventor
Zheng Xin Dong
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/779,768 external-priority patent/US5969095A/en
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Application granted granted Critical
Publication of DK0948541T3 publication Critical patent/DK0948541T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone (parathormone); Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DK97951595T 1997-01-07 1997-12-08 Analoge af PTHrP DK0948541T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/779,768 US5969095A (en) 1995-07-13 1997-01-07 Analogs of parathyroid hormone
US08/813,534 US5955574A (en) 1995-07-13 1997-03-07 Analogs of parathyroid hormone

Publications (1)

Publication Number Publication Date
DK0948541T3 true DK0948541T3 (da) 2006-07-17

Family

ID=27119618

Family Applications (2)

Application Number Title Priority Date Filing Date
DK97951595T DK0948541T3 (da) 1997-01-07 1997-12-08 Analoge af PTHrP
DK05026436.5T DK1645566T3 (da) 1997-01-07 1997-12-08 Parathyroidhormonanaloger

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK05026436.5T DK1645566T3 (da) 1997-01-07 1997-12-08 Parathyroidhormonanaloger

Country Status (24)

Country Link
US (1) US5955574A (es)
EP (3) EP2206725A1 (es)
JP (1) JP3963482B2 (es)
KR (2) KR100699422B1 (es)
CN (1) CN1137898C (es)
AR (3) AR011517A1 (es)
AT (2) ATE321784T1 (es)
AU (1) AU741584B2 (es)
BR (1) BR9714200A (es)
CA (1) CA2276614C (es)
CZ (2) CZ301497B6 (es)
DE (2) DE69739912D1 (es)
DK (2) DK0948541T3 (es)
ES (2) ES2347154T3 (es)
HK (1) HK1026215A1 (es)
HU (1) HUP9904596A3 (es)
IL (1) IL130794A0 (es)
NO (1) NO993341L (es)
NZ (1) NZ336610A (es)
PL (1) PL191898B1 (es)
PT (2) PT1645566E (es)
RU (1) RU2198182C2 (es)
SI (2) SI0948541T1 (es)
WO (1) WO1998030590A2 (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6544949B1 (en) 1995-07-13 2003-04-08 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Analogs of parathyroid hormone
US7410948B2 (en) * 1995-07-13 2008-08-12 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Analogs of parathyroid hormone
BR9812068A (pt) 1997-09-09 2000-09-26 Hoffmann La Roche Processo para a cicatrização óssea e restauração de fraturas e utilização de um análogo de polipeptìdeo de peptìdeo (pthrp) relacionado com hormÈnios de paratireóide e seus sais
EP1075491B1 (en) * 1998-05-05 2008-04-16 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Pth2 receptor selective compounds
DE69941708D1 (de) * 1998-07-20 2010-01-07 Ipsen Pharma Pacap-peptidanaloga
US6660843B1 (en) † 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
AU2000265051A1 (en) * 2000-02-18 2001-08-27 Dabur Research Foundation Vasoactive intestinal peptide analogs
US6756480B2 (en) 2000-04-27 2004-06-29 Amgen Inc. Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
US20050124537A1 (en) * 2000-04-27 2005-06-09 Amgen Inc. Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
PT1397156E (pt) 2001-06-01 2007-05-31 Novartis Ag Método para a administração oral da hormona paratireóide ( pth ).
AU2002339843B2 (en) 2001-07-23 2007-12-06 The General Hospital Corporation Conformationally constrained parathyroid hormone (PTH) analogs
JP2007501241A (ja) * 2003-08-06 2007-01-25 ローディア インコーポレイティド 骨成長を促進する方法
EP1945245A2 (en) 2005-11-10 2008-07-23 The Board of Control of Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
USRE49444E1 (en) 2006-10-03 2023-03-07 Radius Health, Inc. Method of treating osteoporosis comprising administration of PTHrP analog
BRPI0719821B8 (pt) * 2006-10-03 2021-05-25 Ipsen Pharma Sas composição estável na armazenagem apropriada para administração a pacientes
US7803770B2 (en) * 2006-10-03 2010-09-28 Radius Health, Inc. Method of treating osteoporosis comprising administration of PTHrP analog
JP5200027B2 (ja) * 2006-10-13 2013-05-15 イーライ リリー アンド カンパニー Ｐｔｈ受容体モジュレーターとしてのペグ化ｐｔｈおよびその使用
CA3017668C (en) 2007-08-01 2021-11-09 The General Hospital Corporation Screening methods using g-protein coupled receptors and related compositions
EP2411038B1 (en) 2009-03-27 2016-12-28 Van Andel Research Institute Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use
AU2009356227A1 (en) 2009-12-07 2012-06-21 Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
WO2011143469A1 (en) 2010-05-12 2011-11-17 Radius Health,Inc Therapeutic regimens
US9492508B2 (en) 2010-05-13 2016-11-15 The General Hospital Corporation Parathyroid hormone analogs and uses thereof
WO2012047617A1 (en) 2010-09-28 2012-04-12 Radius Health, Inc. Selective androgen receptor modulators
IL307981A (en) 2015-04-29 2023-12-01 Radius Pharmaceuticals Inc Cancer treatment methods
WO2017007777A2 (en) * 2015-07-06 2017-01-12 Zhengxin Dong NOVEL FORMULATIONS OF PTHrP ANALOGUE
WO2017223115A1 (en) 2016-06-22 2017-12-28 Radius Health, Inc. Ar+ breast cancer treatment methods
JP7481115B2 (ja) 2017-01-05 2024-05-10 ラジウス ファーマシューティカルズ，インコーポレイテッド Ｒａｄ１９０１－２ｈｃｌの多形性形態
US10996208B2 (en) 2017-04-28 2021-05-04 Radius Health, Inc. Abaloparatide formulations and methods of testing, storing, modifying, and using same
SG11202013177WA (en) 2018-07-04 2021-01-28 Radius Pharmaceuticals Inc Polymorphic forms of rad 1901-2hcl

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
IE52535B1 (en) 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
FR2550204B1 (fr) * 1983-08-05 1987-11-13 Toyo Jozo Kk Derives peptidiques de (nle8,nle1b, tyr34)-h-pth
EP0293158A3 (en) * 1987-05-26 1990-05-09 Merck & Co. Inc. Parathyroid hormone antagonists
EP0411096A1 (de) * 1989-02-23 1991-02-06 Gesellschaft für Biotechnologische Forschung mbH (GBF) Pth-varianten kodierende dna-sequenzen, pth-varianten, expressionsvektor, bakterieller wirt, verwendung und therapeutische zusammensetzung
CA2040264A1 (en) * 1990-04-12 1991-10-13 Tatsuhiko Kanmera Parathyroid hormone antagonists
JPH0532696A (ja) * 1990-09-28 1993-02-09 Takeda Chem Ind Ltd 副甲状腺ホルモン誘導体
AU2807892A (en) * 1991-10-10 1993-05-03 Peter K.T. Pang Parathyroid hormone analogues and use in osteoporosis treatment
US5434246A (en) * 1992-03-19 1995-07-18 Takeda Chemical Industries, Ltd. Parathyroid hormone derivatives
CA2098639A1 (en) * 1992-06-19 1993-12-20 K. Anne Kronis Bone stimulating, non-vasoactive parathyroid hormone variants
US5821225A (en) * 1992-07-14 1998-10-13 Syntex (U.S.A.) Inc. Method for the treatment of corticosteroid induced osteopenia comprising administration of modified PTH or PTHrp
US5589452A (en) * 1992-07-14 1996-12-31 Syntex (U.S.A.) Inc. Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis
AU672790B2 (en) * 1992-07-15 1996-10-17 Novartis Ag Variants of parathyroid hormone and its fragments
WO1994015587A2 (en) 1993-01-06 1994-07-21 Kinerton Limited Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
CN1070500C (zh) * 1993-07-13 2001-09-05 森德克斯(美国)股份有限公司 甲状旁腺激素类似物和甲状旁腺激素相关肽：合成和治疗骨质疏松症的用途
EP0800405A4 (en) * 1994-12-19 1998-11-11 Beth Israel Hospital CONTINUOUS ADMINISTRATION OF LOW DOSES OF HORMONE PARATHYRO DIENNE OR ITS AGONIST
CA2178894A1 (en) * 1995-06-15 1996-12-16 Tsunehiko Fukuda Parathyroid hormone derivatives and their use
US5723577A (en) * 1995-07-13 1998-03-03 Biomeasure Inc. Analogs of parathyroid hormone

Also Published As

Publication number Publication date
EP0948541A2 (en) 1999-10-13
JP2001508439A (ja) 2001-06-26
WO1998030590A3 (en) 1998-12-10
HUP9904596A3 (en) 2000-07-28
KR20000069952A (ko) 2000-11-25
ES2258286T3 (es) 2006-08-16
WO1998030590A9 (en) 1999-08-19
CN1254347A (zh) 2000-05-24
AR038552A2 (es) 2005-01-19
PL334438A1 (en) 2000-02-28
CA2276614C (en) 2002-06-11
JP3963482B2 (ja) 2007-08-22
BR9714200A (pt) 2000-03-28
EP0948541B1 (en) 2006-03-29
PT948541E (pt) 2006-07-31
ATE321784T1 (de) 2006-04-15
NO993341L (no) 1999-09-06
HK1026215A1 (en) 2000-12-08
CA2276614A1 (en) 1998-07-16
DE69735603D1 (de) 2006-05-18
AR011517A1 (es) 2000-08-30
AU741584B2 (en) 2001-12-06
NO993341D0 (no) 1999-07-06
PL191898B1 (pl) 2006-07-31
KR100497709B1 (ko) 2005-06-23
AR051906A2 (es) 2007-02-14
RU2198182C2 (ru) 2003-02-10
EP1645566A2 (en) 2006-04-12
KR100699422B1 (ko) 2007-03-28
KR20060030006A (ko) 2006-04-07
DE69739912D1 (de) 2010-07-29
ES2347154T3 (es) 2010-10-26
IL130794A0 (en) 2001-01-28
DK1645566T3 (da) 2010-09-27
CZ239899A3 (cs) 2000-01-12
AU5519998A (en) 1998-08-03
ATE471342T1 (de) 2010-07-15
CN1137898C (zh) 2004-02-11
EP2206725A1 (en) 2010-07-14
US5955574A (en) 1999-09-21
DE69735603T2 (de) 2006-11-30
NZ336610A (en) 2001-07-27
HUP9904596A1 (hu) 2000-06-28
WO1998030590A2 (en) 1998-07-16
CZ298937B6 (cs) 2008-03-19
EP1645566A3 (en) 2006-10-11
SI1645566T1 (sl) 2010-11-30
PT1645566E (pt) 2010-08-31
SI0948541T1 (sl) 2006-06-30
EP1645566B1 (en) 2010-06-16
CZ301497B6 (cs) 2010-03-24

Similar Documents

Publication Publication Date Title
DK0948541T3 (da) Analoge af PTHrP
EA199901025A1 (ru) Пептидные аналоги паратиреоидного гормона
DE69638025D1 (de) Parathyroidhormon Analoge
BR9713294A (pt) "anticorpos contra proteìna relacionada a hormÈnio de paratiróide humano"
IL210454A (en) Antibody against a new ligand of cytokine 17zcytor
NZ527053A (en) Modified amyloid precursor protein polynucleotides and polypeptides
DK0682529T4 (da) Antistof til behandling af insulinkrævende diabetes
ATE304020T1 (de) Parathyroidhormon-verwandthe peptidanaloge
TR199700714A2 (xx) Paratiroit hormonu, analoglar�n�n sentezi i�in bir y�ntem.
DK0812856T3 (da) Fremgangsmåde til fjernelse af N-terminalt methionin
NO971508L (no) Analoger av sur fibroblastvekstfaktor med forökt stabilitet og biologisk aktivitet
DK0427863T3 (da) DNA, som koder for protein, som kan kombinere med forstærker for alfa-fetoprotein-gen
DK0923644T3 (da) G-koblet receptor, der udviser selektiv selektivitet for ATP
DK0779297T3 (da) Antigene peptider med glycinsubstitutioner
DK0982399T3 (da) Thyroidhormontransportörer, agonister og antagonister deraf