DK0864645T3 - Negativstrenget RNA-virusvektor med autonom replikeringsaktivitet - Google Patents
Negativstrenget RNA-virusvektor med autonom replikeringsaktivitetInfo
- Publication number
- DK0864645T3 DK0864645T3 DK96935402T DK96935402T DK0864645T3 DK 0864645 T3 DK0864645 T3 DK 0864645T3 DK 96935402 T DK96935402 T DK 96935402T DK 96935402 T DK96935402 T DK 96935402T DK 0864645 T3 DK0864645 T3 DK 0864645T3
- Authority
- DK
- Denmark
- Prior art keywords
- stranded rna
- virus vector
- rna virus
- replication activity
- negative stranded
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18811—Sendai virus
- C12N2760/18821—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18811—Sendai virus
- C12N2760/18822—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18811—Sendai virus
- C12N2760/18841—Use of virus, viral particle or viral elements as a vector
- C12N2760/18843—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18811—Sendai virus
- C12N2760/18851—Methods of production or purification of viral material
- C12N2760/18852—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP30831595 | 1995-10-31 | ||
PCT/JP1996/003068 WO1997016538A1 (fr) | 1995-10-31 | 1996-10-22 | Vecteur de virus d'arn a brin negatif possedant une activite de replication autonome |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0864645T3 true DK0864645T3 (da) | 2005-10-24 |
Family
ID=17979579
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96935402T DK0864645T3 (da) | 1995-10-31 | 1996-10-22 | Negativstrenget RNA-virusvektor med autonom replikeringsaktivitet |
Country Status (10)
Country | Link |
---|---|
US (2) | US6723532B2 (xx) |
EP (2) | EP0864645B9 (xx) |
KR (2) | KR100754091B1 (xx) |
CN (1) | CN1118569C (xx) |
AT (1) | ATE298789T1 (xx) |
AU (1) | AU7335196A (xx) |
DE (1) | DE69634904T2 (xx) |
DK (1) | DK0864645T3 (xx) |
HK (1) | HK1018287A1 (xx) |
WO (1) | WO1997016538A1 (xx) |
Families Citing this family (68)
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CA2236378C (en) | 1995-11-01 | 2011-01-25 | Dnavec Research Inc. | Recombinant sendai virus |
CN1249248C (zh) * | 1998-07-03 | 2006-04-05 | 株式会社载体研究所 | 用于神经细胞转移基因的负链rna病毒载体 |
US7241617B2 (en) | 1998-07-03 | 2007-07-10 | Dnavec Research, Inc. | Sendai viral vectors comprising foreign genes inserted between the R1 and R2 Loci |
WO2000009700A1 (en) * | 1998-08-11 | 2000-02-24 | Dnavec Research Inc. | Rna virus vector having contact infiltration capability |
US6828138B1 (en) | 1998-08-11 | 2004-12-07 | Dnavec Research Inc. | Recombinant sendai virus vector including a gene encoding a chemokine |
US6544785B1 (en) | 1998-09-14 | 2003-04-08 | Mount Sinai School Of Medicine Of New York University | Helper-free rescue of recombinant negative strand RNA viruses |
EP1013667B1 (en) * | 1998-11-09 | 2006-10-11 | Nippon Biologicals, Inc. | Process for preparation of cytokine using a sendai virus expression system |
US6490775B1 (en) * | 1999-04-23 | 2002-12-10 | Veri-Tek Inc. | Press operation verification system |
US20030166252A1 (en) * | 1999-05-18 | 2003-09-04 | Kaio Kitazato | Paramyxovirus-derived RNP |
US7226786B2 (en) | 1999-05-18 | 2007-06-05 | Dnavec Research Inc. | Envelope gene-deficient Paramyxovirus vector |
KR20070058607A (ko) * | 1999-05-18 | 2007-06-08 | 가부시키가이샤 디나벡크 겐큐쇼 | 엔벨로프 유전자 결손 파라믹소과 바이러스 벡터 |
WO2001018223A1 (fr) * | 1999-09-06 | 2001-03-15 | Dnavec Research Inc. | Paramoxyvirus possedant une sequence d'initiation de transcription modifiee |
US7314614B1 (en) | 1999-11-02 | 2008-01-01 | Dnavec Research, Inc. | Recombinant sendai virus vector for introducing exogenous genes to airway epithelia |
JP4838962B2 (ja) * | 1999-11-02 | 2011-12-14 | 株式会社ディナベック研究所 | 気道上皮細胞への外因性遺伝子導入用組換えセンダイウイルスベクター |
US6875436B1 (en) | 1999-11-19 | 2005-04-05 | The Kitasata Institute | Method for producing cell-fushion type morbillivirus mutants |
CN1418252A (zh) * | 2000-01-19 | 2003-05-14 | 株式会社载体研究所 | 副粘病毒属载体在血管内基因转移中的用途 |
EP1270016A4 (en) | 2000-03-30 | 2005-10-19 | Dnavec Research Inc | VACCINE AGAINST AIDS VIRUS CONTAINING A VECTOR OF SENDAI VIRUS |
CA2322057A1 (en) | 2000-05-18 | 2001-11-18 | Dnavec Research Inc. | Paramyxovirus vectors used for transfer of foreign genes |
CN100531802C (zh) * | 2000-06-01 | 2009-08-26 | 株式会社载体研究所 | 含有血凝素活性膜蛋白质的假型逆转录病毒载体 |
US20030170897A1 (en) * | 2000-06-27 | 2003-09-11 | Enyu Imai | Virus vector for transferring gene into renal cells |
EP1333088A4 (en) * | 2000-10-06 | 2004-11-24 | Dnavec Research Inc | PARAMYXOVIRUS VECTOR FOR THE INTRODUCTION OF FOREIGN GENES IN SKELETAL MUSCLE |
JP2002142770A (ja) * | 2000-11-08 | 2002-05-21 | Dnavec Research Inc | 循環系への遺伝子送達用パラミクソウイルスベクター |
WO2002042481A1 (fr) | 2000-11-27 | 2002-05-30 | Dnavec Research Inc. | Vecteur paramyxovirus codant pour un gene d'angiogenese et son utilisation |
US7465456B2 (en) | 2002-04-26 | 2008-12-16 | Medimmune, Llc | Multi plasmid system for the production of influenza virus |
WO2003091401A2 (en) | 2002-04-26 | 2003-11-06 | Medimmune Vaccines, Inc. | Multi plasmid system for the production of influenza virus |
US7402427B2 (en) | 2002-04-30 | 2008-07-22 | Dnavec Research Inc. | Vectors with modified protease-dependent tropism |
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DE602004027537D1 (xx) | 2003-12-23 | 2010-07-15 | Medimmune Inc | |
KR20060129013A (ko) | 2004-01-13 | 2006-12-14 | 가부시키가이샤 디나벡크 겐큐쇼 | 면역자극성 사이토카인을 코드하는 마이너스 가닥 rna 바이러스 벡터를 사용하는 종양의 유전자 치료 |
AU2005206410A1 (en) | 2004-01-22 | 2005-08-04 | Dnavec Research Inc. | Method of producing minus strand RNA virus vector with the use of hybrid promoter containing cytomegalovirus enhancer and avian beta-actin promoter |
JPWO2005071085A1 (ja) * | 2004-01-22 | 2007-09-06 | 株式会社ディナベック研究所 | ウイルスベクターの製造方法 |
US20080199438A1 (en) * | 2004-03-16 | 2008-08-21 | Dnavec Research Inc. | Methods For Suppressing Tumor Proliferation |
JPWO2005097988A1 (ja) * | 2004-03-23 | 2008-02-28 | 株式会社ディナベック研究所 | 組織の維持および/または修復に関連する骨髄関連細胞 |
AU2005248377B2 (en) | 2004-05-25 | 2011-03-24 | Medimmune, Llc | Influenza hemagglutinin and neuraminidase variants |
CN101006172B (zh) | 2004-06-24 | 2012-09-05 | 株式会社载体研究所 | 包含导入了rna病毒的树突状细胞的抗癌剂 |
ES2527503T3 (es) | 2005-03-08 | 2015-01-26 | Medimmune, Llc | Virus influenza reordenantes |
CA2612168A1 (en) | 2005-06-14 | 2006-12-21 | Dnavec Corporation | Methods for producing antibodies |
ES2561060T3 (es) | 2005-10-28 | 2016-02-24 | Id Pharma Co., Ltd. | Transferencia génica en citoblastos epiteliales de las vías respiratorias mediante el uso de vectores de lentivíricos pseudotipados con una proteína espina de virus de ARN |
CN101405389A (zh) * | 2006-01-17 | 2009-04-08 | 生物载体株式会社 | 新型蛋白质表达系统 |
US20090246170A1 (en) | 2006-05-31 | 2009-10-01 | Dnavec Corporation | Therapeutic Agent For Alzheimer's Disease |
CA2658266A1 (en) | 2006-07-13 | 2008-01-17 | Dnavec Corporation | Non-replicating paramyxoviridae virus vector |
US7601356B2 (en) | 2006-07-21 | 2009-10-13 | Medimmune, Llc | Methods and compositions for increasing replication capacity of an influenza virus |
WO2008021959A2 (en) | 2006-08-09 | 2008-02-21 | Medimmune Vaccines, Inc. | Influenza hemagglutinin and neuraminidase variants |
EP2374884A3 (en) | 2006-09-04 | 2012-01-11 | Kyowa Hakko Kirin Co., Ltd. | Human miRNAs isolated from mesenchymal stem cells |
JPWO2008084319A1 (ja) | 2006-12-18 | 2010-04-30 | 協和発酵キリン株式会社 | 新規核酸 |
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WO2008136438A1 (ja) | 2007-04-27 | 2008-11-13 | Kyushu University, National University Corporation | 遺伝子治療用ウイルスベクター |
EP2069484B1 (en) | 2007-06-18 | 2014-08-13 | MedImmune, LLC | Influenza B viruses having alterations in the hemaglutinin polypeptide |
JPWO2009044899A1 (ja) | 2007-10-03 | 2011-02-17 | 協和発酵キリン株式会社 | 細胞の増殖を制御する核酸 |
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EP2322611B1 (en) | 2008-07-16 | 2016-06-01 | IP Pharma Co., Ltd. | Method for production of reprogrammed cell using chromosomally unintegrated virus vector |
EP2363472B1 (en) | 2008-10-31 | 2014-12-10 | Dnavec Corporation | Method for enhancing expression of recombinant protein |
CN102361649A (zh) | 2009-02-12 | 2012-02-22 | 米迪缪尼有限公司 | 流感血凝素和神经氨酸酶变体 |
US8945576B2 (en) | 2010-01-08 | 2015-02-03 | Kyoto University | Vaccine for treatment of tautopathy |
JP5908838B2 (ja) | 2010-08-30 | 2016-04-26 | 株式会社Idファーマ | 多能性幹細胞を誘導するための組成物およびその使用 |
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WO2018092887A1 (ja) | 2016-11-17 | 2018-05-24 | 国立感染症研究所長が代表する日本国 | 非感染性パラミクソウイルス粒子を用いた感染症ワクチン |
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WO1996010400A1 (en) | 1994-09-30 | 1996-04-11 | The Uab Research Foundation | Gene therapy vectors and vaccines based on non-segmented negatives stranded rna viruses |
DK0780475T4 (da) | 1995-08-09 | 2006-10-23 | Schweiz Serum & Impfinst | Fremgangsmåde til fremstilling af infektiöse negativ-streng RNA-virus |
KR0179554B1 (ko) * | 1995-11-30 | 1999-04-15 | 김주용 | 반도체 소자의 소자분리절연막 형성방법 |
JP2000509280A (ja) | 1996-05-01 | 2000-07-25 | アメリカ合衆国 | 組換えdna由来ヌクレオキャプシドタンパク質を用いるウイルストランスフェクタントの作製 |
-
1996
- 1996-10-22 KR KR1020057010921A patent/KR100754091B1/ko not_active IP Right Cessation
- 1996-10-22 KR KR1019980703189A patent/KR100552387B1/ko not_active IP Right Cessation
- 1996-10-22 DE DE69634904T patent/DE69634904T2/de not_active Expired - Lifetime
- 1996-10-22 AT AT96935402T patent/ATE298789T1/de active
- 1996-10-22 CN CN96199467A patent/CN1118569C/zh not_active Expired - Lifetime
- 1996-10-22 EP EP96935402A patent/EP0864645B9/en not_active Expired - Lifetime
- 1996-10-22 AU AU73351/96A patent/AU7335196A/en not_active Abandoned
- 1996-10-22 EP EP03002037A patent/EP1325960A3/en not_active Ceased
- 1996-10-22 DK DK96935402T patent/DK0864645T3/da active
- 1996-10-22 WO PCT/JP1996/003068 patent/WO1997016538A1/ja active IP Right Grant
-
1998
- 1998-04-30 US US09/070,938 patent/US6723532B2/en not_active Expired - Lifetime
-
1999
- 1999-07-17 HK HK99103082A patent/HK1018287A1/xx not_active IP Right Cessation
- 1999-12-23 US US09/471,840 patent/US6645760B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0864645A1 (en) | 1998-09-16 |
AU7335196A (en) | 1997-05-22 |
EP0864645B9 (en) | 2006-03-22 |
KR100754091B1 (ko) | 2007-08-31 |
EP1325960A2 (en) | 2003-07-09 |
KR100552387B1 (ko) | 2006-04-21 |
KR19990067232A (ko) | 1999-08-16 |
CN1207123A (zh) | 1999-02-03 |
CN1118569C (zh) | 2003-08-20 |
EP1325960A3 (en) | 2004-09-15 |
US20020081706A1 (en) | 2002-06-27 |
US6723532B2 (en) | 2004-04-20 |
DE69634904T2 (de) | 2006-05-18 |
DE69634904D1 (de) | 2005-08-04 |
EP0864645B1 (en) | 2005-06-29 |
KR20050084302A (ko) | 2005-08-26 |
US20020100066A1 (en) | 2002-07-25 |
US6645760B2 (en) | 2003-11-11 |
EP0864645A4 (en) | 2000-01-26 |
HK1018287A1 (en) | 1999-12-17 |
WO1997016538A1 (fr) | 1997-05-09 |
ATE298789T1 (de) | 2005-07-15 |
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