ES8608581A1 - Un metodo para la construccion de un gen sintetico para pro-teina objetivo viral - Google Patents

Un metodo para la construccion de un gen sintetico para pro-teina objetivo viral

Info

Publication number
ES8608581A1
ES8608581A1 ES545299A ES545299A ES8608581A1 ES 8608581 A1 ES8608581 A1 ES 8608581A1 ES 545299 A ES545299 A ES 545299A ES 545299 A ES545299 A ES 545299A ES 8608581 A1 ES8608581 A1 ES 8608581A1
Authority
ES
Spain
Prior art keywords
parainfluenza virus
synthetic genes
bovine parainfluenza
synthetic gene
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES545299A
Other languages
English (en)
Other versions
ES545299A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
WR Grace and Co
Original Assignee
WR Grace and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by WR Grace and Co filed Critical WR Grace and Co
Publication of ES8608581A1 publication Critical patent/ES8608581A1/es
Publication of ES545299A0 publication Critical patent/ES545299A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
    • C12N2760/18622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

METODO DE CONSTRUCCION DE GENES SINTETICOS DE PROTEINAS OBJETIVO VIRAL, QUE SE CODIFICAN EN EL ESTADO NATURAL MEDIANTE GENES SITUADOS EN EL GENOMA DE MINUS-FILAMENTO NO SEGMENTADO DEL VIRUS TIPO 3 DE PARAINFLUENCIA BOVINA, QUE TIENE APLICACIONES PARA LA PRODUCCION DE VACUNAS. CONSISTE EN AISLAR UNA POBLACION DE MRNA QUE CONTIENE LOS GENES QUE CODIFICAN LA PROTEINA VIRAL Y FRACCIONARLA PARA SEPARAR MRNA POLIADENILADO; CONSTRUIR A PARTIR DE ELLA HIBRIDOS DE MRNA/CDNA DOBLE FILAMENTADOS MEDIANTE TRANSCRIPTASA INVERSA DE ENZIMA Y MOLECULAS DE CEBO DE OLIGODEOXINUCLEOTIDO QUE SE HIBRIDIZAN AL MRNA POLIADENILADO; DIGERIR O SEPARAR LOS FILAMENTOS DE MRNA DE LOS HIBRIDOS CON UN ALCALI O RIBONUCLEASA; PRODUCIR MOLECULAS DE CDNA MEDIANTE POLIMERASA DE DNA; Y EQUILIBRAR LAS PARTES EXTREMAS DE ESTAS MOLECULAS MEDIANTE UNA NUCLEASA ESPECIFICA.
ES545299A 1984-07-18 1985-07-17 Un metodo para la construccion de un gen sintetico para pro-teina objetivo viral Expired ES8608581A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/632,106 US4743553A (en) 1984-07-18 1984-07-18 Synthetic genes for bovine parainfluenza virus

Publications (2)

Publication Number Publication Date
ES8608581A1 true ES8608581A1 (es) 1986-07-16
ES545299A0 ES545299A0 (es) 1986-07-16

Family

ID=24534103

Family Applications (1)

Application Number Title Priority Date Filing Date
ES545299A Expired ES8608581A1 (es) 1984-07-18 1985-07-17 Un metodo para la construccion de un gen sintetico para pro-teina objetivo viral

Country Status (10)

Country Link
US (1) US4743553A (es)
AU (1) AU588238B2 (es)
BE (1) BE902921A (es)
DE (1) DE3524736A1 (es)
DK (1) DK326185A (es)
ES (1) ES8608581A1 (es)
FR (1) FR2567905B1 (es)
GB (1) GB2161814A (es)
IT (1) IT1187689B (es)
NL (1) NL8502063A (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987003206A1 (en) * 1985-11-25 1987-06-04 Quash Gerard A Modified viral glycoproteins, diagnostic and therapeutic uses therefore
AU602875B2 (en) * 1985-12-18 1990-11-01 British Technology Group Limited Newcastle disease virus gene clones
US5149650A (en) * 1986-01-14 1992-09-22 University Of North Carolina At Chapel Hill Vaccines for human respiratory virus
EP0413695B1 (en) * 1988-04-22 1994-05-04 The Upjohn Company Chimeric glycoproteins containing immunogenic segments of human parainfluenza virus type 3.
NZ230425A (en) * 1988-09-02 1992-07-28 Molecular Eng Ass Production of paramyxovirus fusion (f) protein using recombinant baculovirus expression vector
US5401626A (en) * 1989-06-18 1995-03-28 Fujikura Kasei Co., Ltd. cDNA fragment of the gene for the hemagglutinin neuraminidase of human parainfluenza type 2 virus and materials containing the cDNA fragment
JPH0757200B2 (ja) * 1989-06-19 1995-06-21 藤倉化成株式会社 ヒトパラインフルエンザ２型ウイルス同定用検査薬に用いるｄｎａ断片
JP2649285B2 (ja) * 1990-11-29 1997-09-03 藤倉化成株式会社 ヒトパラインフルエンザ４ａ型ウイルスフュージョンプロテイン遺伝子及び該遺伝子を含む物質
CA2204252A1 (en) * 1994-11-18 1996-05-30 Elizabeth J. Haanes Expression of the bovine parainfluenza virus type 3 hemagglutinin/neuraminidase (hn) glycoprotein in two heterologous systems
US5869036A (en) * 1995-12-08 1999-02-09 St. Louis University Live attenuated vaccines based on CP45 HPIV-3 strain and method to ensure attenuation in such vaccine
US20040175366A1 (en) * 2003-03-07 2004-09-09 Acell, Inc. Scaffold for cell growth and differentiation
US20040176855A1 (en) * 2003-03-07 2004-09-09 Acell, Inc. Decellularized liver for repair of tissue and treatment of organ deficiency

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3501770A (en) * 1967-04-13 1970-03-17 Lilly Co Eli Shipping fever vaccine
DE2323847C3 (de) * 1973-05-11 1979-11-22 Bayer Ag, 5090 Leverkusen Lebendimpfstoff zur Immunisierung von Rindern gegen die Parainfluenza-3-Virus-Infektion
GB1488800A (en) * 1973-11-29 1977-10-12 Wellcome Found Influenza vaccines
US4331589A (en) * 1978-11-22 1982-05-25 Abbott Laboratories Deoxyribonucleic acid synthesis using binding protein extracted from chick embryo fibroblasts
FR2480779B2 (fr) * 1979-08-30 1986-07-18 Anvar Vecteur contenant une sequence nucleotidique de l'antigene de surface du virus de l'hepatite b et procede de fabrication d'une molecule immunogene mettant en oeuvre ce vecteur
US4357421A (en) * 1979-04-02 1982-11-02 G. D. Searle & Co. Synthetic gene coding for influenza hemagglutinin
US4415491A (en) * 1980-01-14 1983-11-15 The Regents Of The University Of California Synthetic vaccine peptide epitomes of hepatitis B surface antigen
US4388299A (en) * 1980-03-31 1983-06-14 Norden Laboratories, Inc. Modified pasteurella bacteria and vaccines prepared therefrom
US4335106A (en) * 1980-03-31 1982-06-15 Norden Laboratories Inc. Processes for the growth of a modified Pasteurella multocida bacteria and preparation of a vaccine therefrom
US4328210A (en) * 1980-03-31 1982-05-04 Norden Laboratories, Inc. Modified Pasteurella bacteria and vaccines prepared therefrom
US4293545A (en) * 1980-03-31 1981-10-06 Norden Laboratories, Inc. Modified Pasteurella multocida bacteria vaccines
US4719177A (en) * 1981-04-20 1988-01-12 Massachusetts Institute Of Technology Production of complementary DNA representing RNA viral sequences by recombinant DNA methods and uses therefor
US4393201A (en) * 1981-11-04 1983-07-12 The Wistar Institute DNA Which codes for glycoprotein of era-strain rabies virus
FR2524487B1 (fr) * 1982-04-05 1985-11-22 Pasteur Institut Fragments d'adn codant pour des polypeptides contenant au moins un determinant antigenique des papillomavirus, notamment du type hpv 1a et polypeptides correspondants
CA1198882A (en) * 1982-04-08 1986-01-07 Marley Tile A.G. Roof tiles
EP0105346B1 (en) * 1982-04-14 1991-11-13 BITTLE, James L. Synthetic picornavirus antigen

Also Published As

Publication number Publication date
BE902921A (fr) 1985-11-18
US4743553A (en) 1988-05-10
FR2567905A1 (fr) 1986-01-24
ES545299A0 (es) 1986-07-16
NL8502063A (nl) 1986-02-17
IT8521609A0 (it) 1985-07-17
AU588238B2 (en) 1989-09-14
AU4441785A (en) 1986-01-23
DE3524736A1 (de) 1986-01-30
DK326185D0 (da) 1985-07-17
IT1187689B (it) 1987-12-23
GB2161814A (en) 1986-01-22
GB8517994D0 (en) 1985-08-21
DK326185A (da) 1986-01-19
FR2567905B1 (fr) 1988-03-11

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960506