DK0817851T5 - DNA, der koder for humant papillomvirus type 18 - Google Patents

DNA, der koder for humant papillomvirus type 18

Info

Publication number
DK0817851T5
DK0817851T5 DK96909743T DK96909743T DK0817851T5 DK 0817851 T5 DK0817851 T5 DK 0817851T5 DK 96909743 T DK96909743 T DK 96909743T DK 96909743 T DK96909743 T DK 96909743T DK 0817851 T5 DK0817851 T5 DK 0817851T5
Authority
DK
Denmark
Prior art keywords
dna encoding
encoding human
human papillomavirus
papillomavirus type
type
Prior art date
Application number
DK96909743T
Other languages
Danish (da)
English (en)
Other versions
DK0817851T3 (da
Inventor
Kathryn J Hofmann
Kathrin U Jansen
Michael P Neeper
Joseph G Joyce
Hugh A George
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27020342&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0817851(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/408,669 external-priority patent/US5840306A/en
Priority claimed from US08/409,122 external-priority patent/US5820870A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK0817851T3 publication Critical patent/DK0817851T3/da
Application granted granted Critical
Publication of DK0817851T5 publication Critical patent/DK0817851T5/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • C12N15/905—Stable introduction of foreign DNA into chromosome using homologous recombination in yeast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/60—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from yeast
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20023—Virus like particles [VLP]

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK96909743T 1995-03-22 1996-03-18 DNA, der koder for humant papillomvirus type 18 DK0817851T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/408,669 US5840306A (en) 1995-03-22 1995-03-22 DNA encoding human papillomavirus type 18
US08/409,122 US5820870A (en) 1995-03-22 1995-03-22 Recombinant human papillomavirus type 18 vaccine

Publications (2)

Publication Number Publication Date
DK0817851T3 DK0817851T3 (da) 2004-08-16
DK0817851T5 true DK0817851T5 (da) 2004-10-25

Family

ID=27020342

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96909743T DK0817851T5 (da) 1995-03-22 1996-03-18 DNA, der koder for humant papillomvirus type 18

Country Status (22)

Country Link
EP (2) EP1422294A1 (it)
JP (1) JPH11502704A (it)
KR (1) KR100430698B1 (it)
CN (1) CN1100876C (it)
AT (1) ATE259879T1 (it)
AU (1) AU714533B2 (it)
CA (1) CA2215834C (it)
CZ (1) CZ291242B6 (it)
DE (4) DE122007000030I1 (it)
DK (1) DK0817851T5 (it)
EA (1) EA001092B1 (it)
ES (1) ES2213772T3 (it)
FR (1) FR07C0023I2 (it)
HU (1) HU223761B1 (it)
IL (1) IL117459A (it)
NL (3) NL300273I1 (it)
NO (1) NO322254B1 (it)
NZ (1) NZ305188A (it)
PL (1) PL184022B1 (it)
PT (1) PT817851E (it)
SK (1) SK284281B6 (it)
WO (1) WO1996029413A2 (it)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9621091D0 (en) 1996-10-09 1996-11-27 Fondation Pour Le Perfectionem Attenuated microorganisms strains and their uses
AU739829B2 (en) * 1997-04-08 2001-10-18 Merck Sharp & Dohme Corp. Stabilized human papillomavirus formulations
ZA982950B (en) 1997-04-08 1998-10-19 Merck & Co Inc Stabilized human papillomavirus formulations
ES2262333T3 (es) * 1998-08-14 2006-11-16 MERCK & CO., INC. Procedimiento para purificar particulas similares a virus de papilomavirus humano.
AUPP765398A0 (en) 1998-12-11 1999-01-14 University Of Queensland, The Treatment of papillomavirus infections
JP4841726B2 (ja) 1999-02-05 2011-12-21 メルク・シャープ・エンド・ドーム・コーポレイション ヒトパピローマウイルスワクチン製剤
FR2795074A1 (fr) * 1999-05-21 2000-12-22 Inst Nat Sante Rech Med Polypeptides transporteurs d'acides amines, et en particulier du glutamate, et procedes de criblage de composes inhibiteurs ou activateurs de l'activite de transport
MY140664A (en) * 2003-09-29 2010-01-15 Merck Sharp & Dohme Optimized expression of hpv 45 l1 in yeast
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
BRPI0811016B1 (pt) 2007-04-29 2021-09-21 Xiamen Innovax Biotech Co., Ltd. Proteína li truncada do papiloma vírus humano tipo 16
WO2008134935A1 (fr) * 2007-04-29 2008-11-13 Beijing Wantai Biological Pharmacy Enterprise Co., Ltd. Protéines 18 l1 de type papillomavirus humain tronqué
CN101440373B (zh) * 2007-11-23 2012-09-05 上海泽润生物科技有限公司 一种截短型的18型人乳头状瘤病毒主要衣壳蛋白l1基因
SG177269A1 (en) * 2009-06-25 2012-02-28 Glaxosmithkline Biolog Sa Novel human papillomavirus (hpv) protein constructs and their use in the prevention of hpv disease
US8871466B2 (en) * 2011-06-15 2014-10-28 Chung-Ang University Industry-Academic Cooperation Foundation Method for enhancing the production yield of human papillomavirus L1 protein
JP2015514696A (ja) 2012-03-18 2015-05-21 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ヒト・パピローマウイルスに対するワクチン接種方法
CN108276491B (zh) * 2018-02-05 2021-01-12 南京薇熙生物医药科技有限公司 一种可特异性识别hpv18 l1蛋白的单克隆抗体及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3625257A1 (de) * 1986-07-23 1988-02-04 Behringwerke Ag Expressionsprodukte der menschlichen papillomviren typ 16 und 18, fuer diese proteine spezifische antikoerper und diese antikoerper bzw. entsprechende dna enthaltende diagnostika
DE4015044A1 (de) * 1990-05-10 1991-11-14 Behringwerke Ag Seroreaktive epitope auf proteinen des menschlichen papillomavirus (hpv) 18
EP1471147A3 (en) * 1991-07-19 2007-03-21 The University Of Queensland Method of making a recombinant molecule for the expression of HPV-16 L1 protein
ATE380871T1 (de) * 1992-06-25 2007-12-15 Univ Georgetown Papillomavirus vakzine
US5437951A (en) * 1992-09-03 1995-08-01 The United States Of America As Represented By The Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
DE122007000090I1 (de) * 1993-03-09 2008-03-27 Univ Rochester Herstellung von menschlichem papillomavirus hüllprotein und virus-ähnlichen teilchen

Also Published As

Publication number Publication date
MX9707208A (es) 1997-11-29
CN1185176A (zh) 1998-06-17
CA2215834C (en) 2007-06-12
EP0817851A2 (en) 1998-01-14
AU5314196A (en) 1996-10-08
EP0817851B9 (en) 2004-08-18
CN1100876C (zh) 2003-02-05
FR07C0023I2 (fr) 2012-08-03
PL184022B1 (pl) 2002-08-30
EA199700256A1 (ru) 1999-06-24
NO974322L (no) 1997-11-24
EA001092B1 (ru) 2000-10-30
EP0817851B1 (en) 2004-02-18
NL300272I1 (nl) 2007-05-01
KR100430698B1 (ko) 2004-07-15
DK0817851T3 (da) 2004-08-16
WO1996029413A2 (en) 1996-09-26
WO1996029413A3 (en) 1996-11-28
AU714533B2 (en) 2000-01-06
NO322254B1 (no) 2006-09-04
JPH11502704A (ja) 1999-03-09
DE122007000031I1 (de) 2007-07-19
EP1422294A1 (en) 2004-05-26
ES2213772T3 (es) 2004-09-01
IL117459A0 (en) 1996-07-23
CZ293697A3 (cs) 1998-02-18
DE122007000025I1 (de) 2007-07-12
PL322333A1 (en) 1998-01-19
NO974322D0 (no) 1997-09-19
NL300273I1 (nl) 2007-05-01
DE69631586D1 (de) 2004-03-25
ATE259879T1 (de) 2004-03-15
DE122007000030I1 (de) 2007-07-19
HUP9801334A3 (en) 1999-04-28
IL117459A (en) 2005-11-20
DE69631586T9 (de) 2005-06-16
HUP9801334A2 (hu) 1998-08-28
NL300271I1 (nl) 2007-05-01
HU223761B1 (hu) 2005-01-28
CA2215834A1 (en) 1996-09-26
FR07C0023I1 (it) 2007-04-27
CZ291242B6 (cs) 2003-01-15
SK284281B6 (sk) 2004-12-01
PT817851E (pt) 2004-06-30
SK127897A3 (en) 1998-07-08
NZ305188A (en) 1999-11-29
DE69631586T2 (de) 2005-01-27

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