DK0807629T3 - Sulfonamidsubstituerede chromaner, fremgangsmåde til fremstilling deraf, anvendelse deraf som medikamenter eller diagnostiske midler samt medikamenter indeholdende dem - Google Patents

Sulfonamidsubstituerede chromaner, fremgangsmåde til fremstilling deraf, anvendelse deraf som medikamenter eller diagnostiske midler samt medikamenter indeholdende dem

Info

Publication number
DK0807629T3
DK0807629T3 DK97107775T DK97107775T DK0807629T3 DK 0807629 T3 DK0807629 T3 DK 0807629T3 DK 97107775 T DK97107775 T DK 97107775T DK 97107775 T DK97107775 T DK 97107775T DK 0807629 T3 DK0807629 T3 DK 0807629T3
Authority
DK
Denmark
Prior art keywords
medicaments
sulfonamide
processes
preparation
diagnostic agents
Prior art date
Application number
DK97107775T
Other languages
Danish (da)
English (en)
Inventor
Joachim Dr Brendel
Heinrich Christian Dr Englert
Uwe Dr Gerlach
Max Dr Hropot
Hans Jochem Dr Lang
Heinz Dr Goegelein
Helmut Dr Bohn
Andreas Dr Herling
Andreas Prof Dr Busch
Rainer Prof Dr Greger
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19619614A external-priority patent/DE19619614A1/de
Priority claimed from DE1996139462 external-priority patent/DE19639462A1/de
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Application granted granted Critical
Publication of DK0807629T3 publication Critical patent/DK0807629T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK97107775T 1996-05-15 1997-05-13 Sulfonamidsubstituerede chromaner, fremgangsmåde til fremstilling deraf, anvendelse deraf som medikamenter eller diagnostiske midler samt medikamenter indeholdende dem DK0807629T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19619614A DE19619614A1 (de) 1996-05-15 1996-05-15 Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE1996139462 DE19639462A1 (de) 1996-09-26 1996-09-26 Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (1)

Publication Number Publication Date
DK0807629T3 true DK0807629T3 (da) 2004-05-17

Family

ID=26025736

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97107775T DK0807629T3 (da) 1996-05-15 1997-05-13 Sulfonamidsubstituerede chromaner, fremgangsmåde til fremstilling deraf, anvendelse deraf som medikamenter eller diagnostiske midler samt medikamenter indeholdende dem

Country Status (24)

Country Link
EP (1) EP0807629B1 (zh)
JP (1) JP4234798B2 (zh)
KR (1) KR100547921B1 (zh)
CN (1) CN1204134C (zh)
AR (2) AR007115A1 (zh)
AT (1) ATE260909T1 (zh)
AU (1) AU711986B2 (zh)
BR (1) BR9703161A (zh)
CA (1) CA2205477A1 (zh)
CZ (1) CZ149497A3 (zh)
DE (1) DE59711352D1 (zh)
DK (1) DK0807629T3 (zh)
ES (1) ES2218617T3 (zh)
HK (1) HK1006640A1 (zh)
HR (1) HRP970255B1 (zh)
HU (1) HUP9700903A3 (zh)
IL (1) IL120827A (zh)
NO (1) NO315556B1 (zh)
NZ (1) NZ314800A (zh)
PL (1) PL191330B1 (zh)
PT (1) PT807629E (zh)
SK (1) SK283837B6 (zh)
TR (1) TR199700369A2 (zh)
TW (1) TW496866B (zh)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ329200A (en) * 1996-12-16 1999-05-28 Hoechst Ag Sulphonamide substituted quinazoline, isoquinoline, quinoline or benzo[1,3-]oxazine derivatives and medicaments
DE19705133A1 (de) * 1997-02-11 1998-08-13 Hoechst Ag Sulfonamid-substituierte Verbindungen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19706675A1 (de) * 1997-02-20 1998-08-27 Hoechst Ag Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
EP0895994A3 (de) 1997-08-05 1999-12-15 Hoechst Marion Roussel Deutschland GmbH Sulfonamid-substituierte Pyranopyridine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19742509A1 (de) * 1997-09-26 1999-04-01 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen
DE19742508A1 (de) 1997-09-26 1999-04-01 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen
DE19748469A1 (de) * 1997-11-03 1999-05-06 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Benzopyranderivate, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen
AU754204B2 (en) 1998-09-01 2002-11-07 Bristol-Myers Squibb Company Potassium channel inhibitors and method
DE19858253A1 (de) 1998-12-17 2000-06-21 Aventis Pharma Gmbh Verwendung von Inhibitoren des KQt1-Kanals zur Herstellung eines Medikaments zur Behandlung von Krankheiten, die durch Helminthen und Ektoparasiten hervorgerufen werden
US7368582B2 (en) 2003-10-17 2008-05-06 Solvay Pharmaceuticals Gmbh Amidomethyl-substituted 2-(4-sulfonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-yl compounds, a process and intermediates for their production, and pharmaceutical compositions containing them
JP4840594B2 (ja) * 2004-03-23 2011-12-21 日産化学工業株式会社 抗不整脈薬としての３環性ベンゾピラン化合物
US7884109B2 (en) 2005-04-05 2011-02-08 Wyeth Llc Purine and imidazopyridine derivatives for immunosuppression
US7989459B2 (en) 2006-02-17 2011-08-02 Pharmacopeia, Llc Purinones and 1H-imidazopyridinones as PKC-theta inhibitors
US7902187B2 (en) 2006-10-04 2011-03-08 Wyeth Llc 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
CL2007002866A1 (es) 2006-10-04 2008-07-04 Pharmacopeia Inc Compuestos derivados de 6-sustituidos-2-(bencimidazolil) purina y purinona; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto en el tratamiento de enfermedades autoinmunes, enfermedad inflamatoria, enfermedad mediada por m
US7915268B2 (en) 2006-10-04 2011-03-29 Wyeth Llc 8-substituted 2-(benzimidazolyl)purine derivatives for immunosuppression
EP2426133B1 (en) * 2009-04-30 2015-12-16 Nissan Chemical Industries, Ltd. Novel crystal forms of tricyclic benzopyran compound and processes for producing same
TWI583677B (zh) * 2012-09-21 2017-05-21 日本臟器製藥股份有限公司 香豆素衍生物
CN103012380B (zh) * 2013-01-10 2015-03-04 山东大学 一种色满类化合物及其制备方法与应用
JP6089055B2 (ja) * 2014-03-20 2017-03-01 日本臓器製薬株式会社 クマリン誘導体を含有する医薬
AR117169A1 (es) 2018-11-28 2021-07-14 Bayer Ag (tio)amidas de piridazina como compuestos fungicidas
BR112022022595A2 (pt) 2020-05-06 2022-12-20 Bayer Ag Piridina (tio)amidas como compostos fungicidas
EP4149929A1 (en) 2020-05-12 2023-03-22 Bayer Aktiengesellschaft Triazine and pyrimidine (thio)amides as fungicidal compounds
EP4153566A1 (en) 2020-05-19 2023-03-29 Bayer CropScience Aktiengesellschaft Azabicyclic(thio)amides as fungicidal compounds
CN115697059A (zh) 2020-05-27 2023-02-03 拜耳公司 活性化合物组合
WO2023078915A1 (en) 2021-11-03 2023-05-11 Bayer Aktiengesellschaft Bis(hetero)aryl thioether (thio)amides as fungicidal compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3737195A1 (de) * 1987-11-03 1989-05-18 Bayer Ag Chromanderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
FR2639349B1 (fr) * 1988-11-23 1991-02-22 Sanofi Sa Nouveaux derives du chromane actifs sur le systeme nerveux central, leur procede de preparation et les compositions pharmaceutiques en contenant
US5104890A (en) * 1989-03-28 1992-04-14 Fujisawa Pharmaceutical Company, Ltd. Benzopyran derivatives and processes for preparation thereof

Also Published As

Publication number Publication date
IL120827A0 (en) 1997-09-30
EP0807629A1 (de) 1997-11-19
PL319995A1 (en) 1997-11-24
TR199700369A2 (xx) 1997-12-21
AU711986B2 (en) 1999-10-28
HK1006640A1 (en) 1999-03-12
AU2080697A (en) 1997-11-20
HU9700903D0 (en) 1997-07-28
CN1204134C (zh) 2005-06-01
ES2218617T3 (es) 2004-11-16
HRP970255A2 (en) 1998-04-30
AR010314A1 (es) 2000-06-07
TW496866B (en) 2002-08-01
NZ314800A (en) 1999-02-25
PL191330B1 (pl) 2006-04-28
HRP970255B1 (en) 2003-10-31
SK60397A3 (en) 1998-02-04
CZ149497A3 (en) 1997-12-17
EP0807629B1 (de) 2004-03-03
KR100547921B1 (ko) 2006-10-19
JPH1067772A (ja) 1998-03-10
ATE260909T1 (de) 2004-03-15
KR19980024020A (ko) 1998-07-06
CN1169429A (zh) 1998-01-07
HUP9700903A3 (en) 1999-03-01
NO315556B1 (no) 2003-09-22
PT807629E (pt) 2004-07-30
IL120827A (en) 2004-12-15
MX9703534A (es) 1997-11-29
DE59711352D1 (de) 2004-04-08
NO972211D0 (no) 1997-05-14
AR007115A1 (es) 1999-10-13
SK283837B6 (sk) 2004-03-02
CA2205477A1 (en) 1997-11-15
JP4234798B2 (ja) 2009-03-04
NO972211L (no) 1997-11-17
HUP9700903A2 (hu) 1998-12-28
BR9703161A (pt) 1998-09-29

Similar Documents

Publication Publication Date Title
DK0807629T3 (da) Sulfonamidsubstituerede chromaner, fremgangsmåde til fremstilling deraf, anvendelse deraf som medikamenter eller diagnostiske midler samt medikamenter indeholdende dem
NO964639L (no) Substituerte sulfonimidamider, fremgangsmåte for fremstilling derav, deres anvendelse som medikament eller diagnostikum samt medikament inneholdende forbindelsen
DK0825178T3 (da) Phenylsubstituerede alkenylcarboxylsyreguanidider, fremgangsmåde til deres fremstilling, deres anvendelse som lægemiddel eller diagnostikum samt lægemiddel med indhold deraf
NO962006D0 (no) Substituerte benzyloksykarbonylguanidiner, fremgangsmåte for deres fremstilling, deres anvendelse som medikament eller diagnostikum såvel som legemiddel inneholdende dem
FI960369A0 (fi) Emässubstituoituja bentsoyyliguanidiinejä, menetelmä niiden valmistamiseksi, niiden käyttö lääkeaineena tai diagnostisena aineena sekä niitä sisältävänä lääkkeenä
NO972433D0 (no) Substituerte 2-naftoylguanidiner, fremgangsmåter for deres fremstilling, deres anvendelse som medikament eller diagnostikum samt medikamenter inneholdende forbindelsene
NO960627L (no) Substituerte benzolsulfonylurinstoffer, fremgangsmåte for deres fremstilling, deres anvendelse som medikament eller diagnostikum samt legemidler inneholdende dem
NO980694D0 (no) Sulfonamidsubstituerte kromaner, fremgangsmåte for deres fremstilling, deres anvendelse som medikament eller diagnostika såvel som medikamenter inneholdende dem
NO964053D0 (no) Substituerte benzoylguanidiner, fremgangsmåte for fremstilling derav, deres anvendelse som medikament eller diagnostikum samt medikamenter inneholdende forbindelsene
FI953173A (fi) Orto-aminosubstituoituja bentsolyyliguanidiinejä, menetelmä niiden valmistamiseksi, niiden käyttö lääkeaineena tai diagnostisena aineena sekä niitä sisältävä lääkeaine
NO984476L (no) Sulfonamidsubstituerte kromaner, fremgangsmÕte for fremstilling derav, deres anvendelse som medikament samt farmas°ytiske preparater inneholdende forbindelsene
DK0811610T3 (da) Ortho-substituerede benzoylguanidiner, fremgangsmåde til deres fremstilling, deres anvendelse som lægemiddel eller diagnostisk middel samt lægemiddel indeholdende dem
DK0810205T3 (da) Substituerede 1-naphthoylguanidiner, fremgangsmåde til deres fremstiling, deres anvendelse som lægemiddel eller diagnostisk middel samt lægemiddel indeholdende dem
DK0754680T3 (da) 4-Fluoralkyl-substituerede benzoylguanidiner, fremgangsmåde til deres fremstilling, deres anvendelse som lægemiddel eller diagnostikum samt lægemiddel med indhold deraf
DK0822182T3 (da) Substituerede indanylidenacetylguanidiner som Na+/H+-udveks-lingsinhibitorer, fremgangsmåde til deres fremstilling, deres anvendelse om lægemidler eller diagnostiske midler samt lægemidler indeholdende dem
DK0905131T3 (da) Sulfonamidsubstituerede chromaner, fremgangsmåde til fremstilling deraf, anvendelse deraf som lægemidler og farmaceutiske præparater indeholdende dem
NO954739D0 (no) Substituerte benzoylguanidiner, fremgangsmåte for fremstilling derav, deres anvendelse som medikament eller diagnostikum samt medikamenter inneholdende disse forbindelsene
NO983577D0 (no) Sulfonamidsubstituerte forbindelser, fremgangsmåter for deres fremstilling, deres anvendelse som medikament eller diagnostikum, samt medikament inneholdende forbindelsen
NO980564D0 (no) Sulfonamid-substituerte forbindelser, fremgangsmåte for fremstilling, anvendelse som medikament eller diagnostikum samt oppnådd medikament er beskrevet
NO964812D0 (no) Sulfonylamino-substituerte benzoylguanidiner, deres fremstilling, deres anvendelse som medikament eller diagnostikum samt medikamenter inneholdende forbindelsene
NO970697L (no) Substituerte tiofenalkenylkarboksylsyreguanidider, fremgangsmåter for deres fremstilling, deres anvendelse som medikament eller diagnostikum samt medikament inneholdende forbindelsene
NO972406D0 (no) Bis-orto-substituerte benzoylguanidiner, fremgangsmåte for fremstilling derav, deres anvendelse som medikament eller diagnostikum samt medikamenter inneholdende forbindelsene
NO995724D0 (no) Nye nitrometylketoner, fremgangsmåter for fremstilling av dem, samt preparater som inneholder dem
DK0729954T3 (da) Substituerede thiophenylsulfonylurinstoffer og -thiourinstoffer, fremgangsmåde til deres fremstilling, deres anvendelse som lægemiddel eller diagnostikum samt lægemiddel med indhold deraf
NO970406D0 (no) Substituerte diaryldikarboksylsyrediguanidiner, fremgangsmåte for deres fremstilling, deres anvendelse som medikamenter eller diagnostika såvel som medikamenter inneholdende dem