AR007115A1 - Cromanos sustituidos con sulfonamida, procedimiento para su preparacion, su empleo para la preparacion de medicamento o agente de diagnostico, asi como medicamento que los contiene - Google Patents

Cromanos sustituidos con sulfonamida, procedimiento para su preparacion, su empleo para la preparacion de medicamento o agente de diagnostico, asi como medicamento que los contiene

Info

Publication number
AR007115A1
AR007115A1 ARP970101998A ARP970101998A AR007115A1 AR 007115 A1 AR007115 A1 AR 007115A1 AR P970101998 A ARP970101998 A AR P970101998A AR P970101998 A ARP970101998 A AR P970101998A AR 007115 A1 AR007115 A1 AR 007115A1
Authority
AR
Argentina
Prior art keywords
preparation
medicinal product
treatment
sulfonamide
arrhythmias
Prior art date
Application number
ARP970101998A
Other languages
English (en)
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19619614A external-priority patent/DE19619614A1/de
Priority claimed from DE1996139462 external-priority patent/DE19639462A1/de
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of AR007115A1 publication Critical patent/AR007115A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6

Abstract

Cromados sustituidos con sulfonamida de la fórmula (I), con los significados de R(1) a R(8) indicados en las reivindicaciones sonextraordinariamente adecuados para la preparación de un medicamento para bloquear el canal de K+, quees abierto por adenosina-monofosfato cíclico(cAMP); además, para la preparación de un medicamento para la inhibición de la secreción de ácidos gástricos; para el tratamiento de úlceras delestómago y de la zona intestinal, en particular delduo deno, para el tratamiento de la esofaguitis recurrente, para el tratamiento de enfermedadesde diarrea, para el tratamiento y la prevención de todos los tipos de arritmias, incluidas arritmias ventriculares ysupraventriculares, a sí comopara el control de arritmias recurrentes y para evitar la muerte repentina del corazón como consecuencia de fibrilaciones ventriculares.
ARP970101998A 1996-05-15 1997-05-13 Cromanos sustituidos con sulfonamida, procedimiento para su preparacion, su empleo para la preparacion de medicamento o agente de diagnostico, asi como medicamento que los contiene AR007115A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19619614A DE19619614A1 (de) 1996-05-15 1996-05-15 Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE1996139462 DE19639462A1 (de) 1996-09-26 1996-09-26 Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (1)

Publication Number Publication Date
AR007115A1 true AR007115A1 (es) 1999-10-13

Family

ID=26025736

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP970101998A AR007115A1 (es) 1996-05-15 1997-05-13 Cromanos sustituidos con sulfonamida, procedimiento para su preparacion, su empleo para la preparacion de medicamento o agente de diagnostico, asi como medicamento que los contiene
ARP970105574A AR010314A1 (es) 1996-05-15 1997-11-26 Empleo de cromanos sustituidos con sulfonamida, como medicamento o agente de diagnostico

Family Applications After (1)

Application Number Title Priority Date Filing Date
ARP970105574A AR010314A1 (es) 1996-05-15 1997-11-26 Empleo de cromanos sustituidos con sulfonamida, como medicamento o agente de diagnostico

Country Status (24)

Country Link
EP (1) EP0807629B1 (es)
JP (1) JP4234798B2 (es)
KR (1) KR100547921B1 (es)
CN (1) CN1204134C (es)
AR (2) AR007115A1 (es)
AT (1) ATE260909T1 (es)
AU (1) AU711986B2 (es)
BR (1) BR9703161A (es)
CA (1) CA2205477A1 (es)
CZ (1) CZ149497A3 (es)
DE (1) DE59711352D1 (es)
DK (1) DK0807629T3 (es)
ES (1) ES2218617T3 (es)
HK (1) HK1006640A1 (es)
HR (1) HRP970255B1 (es)
HU (1) HUP9700903A3 (es)
IL (1) IL120827A (es)
NO (1) NO315556B1 (es)
NZ (1) NZ314800A (es)
PL (1) PL191330B1 (es)
PT (1) PT807629E (es)
SK (1) SK283837B6 (es)
TR (1) TR199700369A2 (es)
TW (1) TW496866B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ329200A (en) * 1996-12-16 1999-05-28 Hoechst Ag Sulphonamide substituted quinazoline, isoquinoline, quinoline or benzo[1,3-]oxazine derivatives and medicaments
DE19705133A1 (de) * 1997-02-11 1998-08-13 Hoechst Ag Sulfonamid-substituierte Verbindungen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19706675A1 (de) * 1997-02-20 1998-08-27 Hoechst Ag Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
EP0895994A3 (de) 1997-08-05 1999-12-15 Hoechst Marion Roussel Deutschland GmbH Sulfonamid-substituierte Pyranopyridine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19742509A1 (de) * 1997-09-26 1999-04-01 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen
DE19742508A1 (de) 1997-09-26 1999-04-01 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen
DE19748469A1 (de) * 1997-11-03 1999-05-06 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Benzopyranderivate, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen
AU754204B2 (en) 1998-09-01 2002-11-07 Bristol-Myers Squibb Company Potassium channel inhibitors and method
DE19858253A1 (de) 1998-12-17 2000-06-21 Aventis Pharma Gmbh Verwendung von Inhibitoren des KQt1-Kanals zur Herstellung eines Medikaments zur Behandlung von Krankheiten, die durch Helminthen und Ektoparasiten hervorgerufen werden
US7368582B2 (en) 2003-10-17 2008-05-06 Solvay Pharmaceuticals Gmbh Amidomethyl-substituted 2-(4-sulfonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-yl compounds, a process and intermediates for their production, and pharmaceutical compositions containing them
JP4840594B2 (ja) * 2004-03-23 2011-12-21 日産化学工業株式会社 抗不整脈薬としての３環性ベンゾピラン化合物
US7884109B2 (en) 2005-04-05 2011-02-08 Wyeth Llc Purine and imidazopyridine derivatives for immunosuppression
US7989459B2 (en) 2006-02-17 2011-08-02 Pharmacopeia, Llc Purinones and 1H-imidazopyridinones as PKC-theta inhibitors
US7902187B2 (en) 2006-10-04 2011-03-08 Wyeth Llc 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
CL2007002866A1 (es) 2006-10-04 2008-07-04 Pharmacopeia Inc Compuestos derivados de 6-sustituidos-2-(bencimidazolil) purina y purinona; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto en el tratamiento de enfermedades autoinmunes, enfermedad inflamatoria, enfermedad mediada por m
US7915268B2 (en) 2006-10-04 2011-03-29 Wyeth Llc 8-substituted 2-(benzimidazolyl)purine derivatives for immunosuppression
EP2426133B1 (en) * 2009-04-30 2015-12-16 Nissan Chemical Industries, Ltd. Novel crystal forms of tricyclic benzopyran compound and processes for producing same
TWI583677B (zh) * 2012-09-21 2017-05-21 日本臟器製藥股份有限公司 香豆素衍生物
CN103012380B (zh) * 2013-01-10 2015-03-04 山东大学 一种色满类化合物及其制备方法与应用
JP6089055B2 (ja) * 2014-03-20 2017-03-01 日本臓器製薬株式会社 クマリン誘導体を含有する医薬
AR117169A1 (es) 2018-11-28 2021-07-14 Bayer Ag (tio)amidas de piridazina como compuestos fungicidas
BR112022022595A2 (pt) 2020-05-06 2022-12-20 Bayer Ag Piridina (tio)amidas como compostos fungicidas
EP4149929A1 (en) 2020-05-12 2023-03-22 Bayer Aktiengesellschaft Triazine and pyrimidine (thio)amides as fungicidal compounds
EP4153566A1 (en) 2020-05-19 2023-03-29 Bayer CropScience Aktiengesellschaft Azabicyclic(thio)amides as fungicidal compounds
CN115697059A (zh) 2020-05-27 2023-02-03 拜耳公司 活性化合物组合
WO2023078915A1 (en) 2021-11-03 2023-05-11 Bayer Aktiengesellschaft Bis(hetero)aryl thioether (thio)amides as fungicidal compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3737195A1 (de) * 1987-11-03 1989-05-18 Bayer Ag Chromanderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
FR2639349B1 (fr) * 1988-11-23 1991-02-22 Sanofi Sa Nouveaux derives du chromane actifs sur le systeme nerveux central, leur procede de preparation et les compositions pharmaceutiques en contenant
US5104890A (en) * 1989-03-28 1992-04-14 Fujisawa Pharmaceutical Company, Ltd. Benzopyran derivatives and processes for preparation thereof

Also Published As

Publication number Publication date
IL120827A0 (en) 1997-09-30
EP0807629A1 (de) 1997-11-19
PL319995A1 (en) 1997-11-24
TR199700369A2 (xx) 1997-12-21
AU711986B2 (en) 1999-10-28
HK1006640A1 (en) 1999-03-12
AU2080697A (en) 1997-11-20
HU9700903D0 (en) 1997-07-28
CN1204134C (zh) 2005-06-01
ES2218617T3 (es) 2004-11-16
HRP970255A2 (en) 1998-04-30
AR010314A1 (es) 2000-06-07
TW496866B (en) 2002-08-01
NZ314800A (en) 1999-02-25
PL191330B1 (pl) 2006-04-28
HRP970255B1 (en) 2003-10-31
SK60397A3 (en) 1998-02-04
CZ149497A3 (en) 1997-12-17
EP0807629B1 (de) 2004-03-03
KR100547921B1 (ko) 2006-10-19
JPH1067772A (ja) 1998-03-10
ATE260909T1 (de) 2004-03-15
KR19980024020A (ko) 1998-07-06
CN1169429A (zh) 1998-01-07
DK0807629T3 (da) 2004-05-17
HUP9700903A3 (en) 1999-03-01
NO315556B1 (no) 2003-09-22
PT807629E (pt) 2004-07-30
IL120827A (en) 2004-12-15
MX9703534A (es) 1997-11-29
DE59711352D1 (de) 2004-04-08
NO972211D0 (no) 1997-05-14
SK283837B6 (sk) 2004-03-02
CA2205477A1 (en) 1997-11-15
JP4234798B2 (ja) 2009-03-04
NO972211L (no) 1997-11-17
HUP9700903A2 (hu) 1998-12-28
BR9703161A (pt) 1998-09-29

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