AR010587A1 - 3-amido-cromanisulfonil(tio)ureas, procedimiento para su preparacion, su empleo y preparados farmaceuticos que las contienen - Google Patents

3-amido-cromanisulfonil(tio)ureas, procedimiento para su preparacion, su empleo y preparados farmaceuticos que las contienen

Info

Publication number
AR010587A1
AR010587A1 ARP970105282A ARP970105282A AR010587A1 AR 010587 A1 AR010587 A1 AR 010587A1 AR P970105282 A ARP970105282 A AR P970105282A AR P970105282 A ARP970105282 A AR P970105282A AR 010587 A1 AR010587 A1 AR 010587A1
Authority
AR
Argentina
Prior art keywords
atoms
alkyl
signifies
alkoxy
different
Prior art date
Application number
ARP970105282A
Other languages
English (en)
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of AR010587A1 publication Critical patent/AR010587A1/es

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

3-amido-cromanilsulfonil(tio)ureas, que comprende la formula (I), en que R(1) significa hidrogeno, alquilo con 1, 2, 3 o 4 átomos de C, alcoxi con 1, 2,3 o 4 átomos de C, alcoxialcoxi con 1, 2, 3 o 4 átomos de C independientes uno de otro encada una de las dos unidades alcoxi, alquilmercapto con 1, 2, 3 o 4átomos de C, fluor, cloro, bromo, yodo o trifluorometilo; R(2a), R(2b) y R(2c), que son iguales o diferentes, significan hidrogeno o alquilo con 1 o 2 átomosde C; R(3) significahidrogeno o alquilo con 1, 2, 3 o 4 átomos de C; Z significa azufre o oxígeno; A significa fenilo, que no está sustituido o estásustituido con hasta tres sustituyentes, iguales o diferentes, elegidos del grupo consistente en halogeno,alquilo con 1 o 2 átomos de C y alcoxi con 1 o 2átomos de C; o A significa el radical de una lactama saturada o insaturada, de la formula (II) en la que B significa alquenileno o alquileno con 3, 4, 5 o 6átomos C, que no está sustituido o estásustituido con ha sta tres grupos alquilo, iguales o diferentes, con 1, 2, 3 o 4 átomos de C, o A significael radical de un sistema bicíclico de las formulas (III) en todas sus formas estereoisomeras y mezclas de las mismas en todas lasrelaciones; así como sussales fisiologicamente inocuas, que son valiosos activos medicamentos para el tratamiento de trastornos del sistema circulatorio del corazon, enparticular para el tratamiento de arritmias, para evitar la muerte repentinapor parálisis card íaca o para influir en una contractilidad reducida delcorazon, así como a procedimientos para su preparacion, a su empleo y a preparados farmacéuticos que las contienen.
ARP970105282A 1996-11-14 1997-11-12 3-amido-cromanisulfonil(tio)ureas, procedimiento para su preparacion, su empleo y preparados farmaceuticos que las contienen AR010587A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19647000A DE19647000A1 (de) 1996-11-14 1996-11-14 3-Amido-chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate

Publications (1)

Publication Number Publication Date
AR010587A1 true AR010587A1 (es) 2000-06-28

Family

ID=7811609

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP970105282A AR010587A1 (es) 1996-11-14 1997-11-12 3-amido-cromanisulfonil(tio)ureas, procedimiento para su preparacion, su empleo y preparados farmaceuticos que las contienen

Country Status (28)

Country Link
US (1) US5849755A (es)
EP (1) EP0842927B1 (es)
JP (1) JP4242936B2 (es)
KR (1) KR100510390B1 (es)
CN (1) CN1101815C (es)
AR (1) AR010587A1 (es)
AT (1) ATE260270T1 (es)
AU (1) AU721063B2 (es)
CA (1) CA2220533C (es)
CZ (1) CZ292257B6 (es)
DE (2) DE19647000A1 (es)
DK (1) DK0842927T3 (es)
ES (1) ES2216094T3 (es)
HR (1) HRP970603B1 (es)
HU (1) HU226108B1 (es)
ID (1) ID18817A (es)
IL (1) IL122173A (es)
MY (1) MY117006A (es)
NO (1) NO317152B1 (es)
NZ (1) NZ329160A (es)
PL (1) PL192113B1 (es)
PT (1) PT842927E (es)
RU (1) RU2195459C2 (es)
SI (1) SI0842927T1 (es)
SK (1) SK282213B6 (es)
TR (1) TR199701342A2 (es)
TW (1) TW474931B (es)
ZA (1) ZA9710243B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000001685A1 (en) 1998-07-06 2000-01-13 Eastman Chemical Company Preparation of tocopherols
AU2830800A (en) * 1999-03-25 2000-10-16 Nissan Chemical Industries Ltd. Chroman derivatives
US7470798B2 (en) * 2003-09-19 2008-12-30 Edison Pharmaceuticals, Inc. 7,8-bicycloalkyl-chroman derivatives
DE102004061017A1 (de) * 2004-12-18 2006-06-22 Sanofi-Aventis Deutschland Gmbh Piperidinsulfonylharnstoffe und -thioharnstoffe, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
CN102193316B (zh) * 2010-03-15 2015-11-18 富士胶片株式会社 正型感光性树脂组合物、固化膜的形成方法、固化膜、有机el显示装置以及液晶显示装置
EP2613198B1 (en) * 2010-08-30 2016-12-28 FUJIFILM Corporation Photosensitive resin composition, oxime sulfonate compound, method for forming cured film, cured film, organic el display device, and liquid crystal display device
JP5650078B2 (ja) * 2010-08-30 2015-01-07 富士フイルム株式会社 感光性樹脂組成物、オキシムスルホネート化合物、硬化膜の形成方法、硬化膜、有機el表示装置、及び、液晶表示装置
AU2011333311A1 (en) * 2010-11-24 2013-07-04 Stemergie Biotechnology Sa Inhibitors of the activity of Complex III of the mitochondrial electron transport chain and use thereof for treating diseases
CN102229551B (zh) * 2011-04-29 2014-07-02 浙江工业大学 一种异硫氰酸酯的制备方法
CN103149795A (zh) * 2011-12-06 2013-06-12 富士胶片株式会社 树脂图案、图案基板、薄膜晶体管基板、层间绝缘膜及显示装置的制造方法
CN104412161A (zh) * 2012-06-28 2015-03-11 富士胶片株式会社 感光性树脂组合物、硬化物及其制造方法、树脂图案制造方法、硬化膜、液晶显示装置、有机el显示装置以及触摸屏显示装置
USD897808S1 (en) * 2019-01-02 2020-10-06 Zhejiang Xingda Stationery Co. Ltd. Utility knife
USD897809S1 (en) * 2019-01-02 2020-10-06 Zhejiang Xingda Stationery Co. Ltd. Utility knife

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2673024B2 (ja) * 1988-01-15 1997-11-05 アボツト・ラボラトリーズ アミノメチル‐クロマン及び‐チオクロマン化合物
DE3926001A1 (de) * 1989-08-05 1991-02-07 Merck Patent Gmbh Chromanderivate
EP0412939A3 (en) * 1989-08-11 1991-09-04 Ciba-Geigy Ag Certain benzopyran and benzothiopyran derivatives
US5374643A (en) * 1992-09-11 1994-12-20 E. R. Squibb & Sons, Inc. Aryl urea (thiourea) and cyanoguanidine derivatives
EP0612724B1 (de) * 1993-02-23 1996-12-27 Hoechst Aktiengesellschaft Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe- Verfahren zu ihrer Herstellung und ihre Verwendung als Pharmazeutika
FR2711139B1 (fr) * 1993-10-15 1995-12-01 Adir Nouveaux dérivés de 1,2,3,4-tétrahydronaphtalène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
US5578671A (en) * 1994-12-30 1996-11-26 Minnesota Mining And Manufacturing Company Intumescent putty
DE19505397A1 (de) * 1995-02-17 1996-08-22 Hoechst Ag Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19546736A1 (de) * 1995-12-14 1997-06-19 Hoechst Ag Substituierte Chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate
KR101939895B1 (ko) * 2017-03-24 2019-01-17 김주옥 선반 조절 장치

Also Published As

Publication number Publication date
MY117006A (en) 2004-04-30
HU9701984D0 (en) 1998-01-28
NO317152B1 (no) 2004-08-30
JPH10139775A (ja) 1998-05-26
DE59711332D1 (de) 2004-04-01
TW474931B (en) 2002-02-01
DK0842927T3 (da) 2004-06-21
AU4515497A (en) 1998-05-21
CZ292257B6 (cs) 2003-08-13
MX9708783A (es) 1998-05-31
HUP9701984A1 (hu) 1998-12-28
EP0842927B1 (de) 2004-02-25
AU721063B2 (en) 2000-06-22
RU2195459C2 (ru) 2002-12-27
KR19980042412A (ko) 1998-08-17
ES2216094T3 (es) 2004-10-16
ID18817A (id) 1998-05-14
ZA9710243B (en) 1998-05-14
PT842927E (pt) 2004-06-30
JP4242936B2 (ja) 2009-03-25
TR199701342A2 (xx) 1998-08-21
EP0842927A1 (de) 1998-05-20
IL122173A (en) 2001-09-13
KR100510390B1 (ko) 2005-11-28
SK152097A3 (en) 1998-07-08
SI0842927T1 (en) 2004-06-30
PL192113B1 (pl) 2006-08-31
NO975214D0 (no) 1997-11-13
DE19647000A1 (de) 1998-05-20
HUP9701984A3 (en) 1999-03-01
IL122173A0 (en) 1998-04-05
US5849755A (en) 1998-12-15
CN1182741A (zh) 1998-05-27
CN1101815C (zh) 2003-02-19
CA2220533C (en) 2007-09-18
HRP970603B1 (en) 2002-08-31
NO975214L (no) 1998-05-15
ATE260270T1 (de) 2004-03-15
HRP970603A2 (en) 1998-08-31
CA2220533A1 (en) 1998-05-14
SK282213B6 (sk) 2001-12-03
NZ329160A (en) 1998-10-28
CZ358897A3 (cs) 1998-06-17
PL322943A1 (en) 1998-05-25
HU226108B1 (en) 2008-04-28

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Legal Events

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