DK0754680T3 - 4-Fluoralkyl-substituerede benzoylguanidiner, fremgangsmåde til deres fremstilling, deres anvendelse som lægemiddel eller diagnostikum samt lægemiddel med indhold deraf - Google Patents

4-Fluoralkyl-substituerede benzoylguanidiner, fremgangsmåde til deres fremstilling, deres anvendelse som lægemiddel eller diagnostikum samt lægemiddel med indhold deraf

Info

Publication number
DK0754680T3
DK0754680T3 DK96111359T DK96111359T DK0754680T3 DK 0754680 T3 DK0754680 T3 DK 0754680T3 DK 96111359 T DK96111359 T DK 96111359T DK 96111359 T DK96111359 T DK 96111359T DK 0754680 T3 DK0754680 T3 DK 0754680T3
Authority
DK
Denmark
Prior art keywords
drug
fluoroalkyl
diagnostic
preparation
substituted benzoylguanidines
Prior art date
Application number
DK96111359T
Other languages
English (en)
Inventor
Andreas Dr Weichert
Joachim Dr Brendel
Heinz-Werner Dr Kleemann
Hans Jochen Dr Lang
Jan-Robert Dr Schwark
Wolfgang Dr Scholz
Udo Dr Albus
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Application granted granted Critical
Publication of DK0754680T3 publication Critical patent/DK0754680T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/45—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/52—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton the carbon skeleton being further substituted by doubly-bound oxygen atoms
    • C07C309/53—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton the carbon skeleton being further substituted by doubly-bound oxygen atoms the carbon skeleton containing carbon atoms of quinone rings
    • C07C309/54—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton the carbon skeleton being further substituted by doubly-bound oxygen atoms the carbon skeleton containing carbon atoms of quinone rings at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK96111359T 1995-07-19 1996-07-15 4-Fluoralkyl-substituerede benzoylguanidiner, fremgangsmåde til deres fremstilling, deres anvendelse som lægemiddel eller diagnostikum samt lægemiddel med indhold deraf DK0754680T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19526381A DE19526381A1 (de) 1995-07-19 1995-07-19 4-Fluoralkyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (1)

Publication Number Publication Date
DK0754680T3 true DK0754680T3 (da) 2002-04-15

Family

ID=7767257

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96111359T DK0754680T3 (da) 1995-07-19 1996-07-15 4-Fluoralkyl-substituerede benzoylguanidiner, fremgangsmåde til deres fremstilling, deres anvendelse som lægemiddel eller diagnostikum samt lægemiddel med indhold deraf

Country Status (28)

Country Link
US (1) US6156800A (da)
EP (1) EP0754680B1 (da)
JP (1) JPH0931045A (da)
KR (1) KR970006282A (da)
CN (1) CN1072644C (da)
AR (1) AR003461A1 (da)
AT (1) ATE211463T1 (da)
AU (1) AU704649B2 (da)
BR (1) BR9603112A (da)
CA (1) CA2181515A1 (da)
CZ (1) CZ291240B6 (da)
DE (2) DE19526381A1 (da)
DK (1) DK0754680T3 (da)
ES (1) ES2170183T3 (da)
HR (1) HRP960343B1 (da)
HU (1) HUP9601976A3 (da)
IL (1) IL118887A (da)
MX (1) MX9602841A (da)
NO (1) NO306612B1 (da)
NZ (1) NZ299015A (da)
PL (1) PL183906B1 (da)
PT (1) PT754680E (da)
RU (1) RU2165412C2 (da)
SI (1) SI0754680T1 (da)
SK (1) SK281604B6 (da)
TR (1) TR199600588A2 (da)
TW (1) TW462960B (da)
ZA (1) ZA966106B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19526381A1 (de) * 1995-07-19 1997-01-23 Hoechst Ag 4-Fluoralkyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
CA2337087C (en) * 2000-03-08 2006-06-06 Canon Kabushiki Kaisha Magnetic toner, process for production thereof, and image forming method, apparatus and process cartridge using the toner
DE10222192A1 (de) * 2002-05-18 2003-11-27 Aventis Pharma Gmbh Pentafluorsulfuranyl-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
US7375138B2 (en) * 2002-05-18 2008-05-20 Sanofi-Aventis Deutschland Gmbh Pentafluorosulfanylbenzoylguanidines, processes for their preparation, their use as medicaments or diagnostic aids, and medicaments comprising them
OA13285A (en) * 2003-11-13 2007-01-31 Sanofi Aventis Deutschland Pentafluorosulfanyl benzoylguanidines, method for their production, their use as medicaments or diagnostic agents and medicament containing the same.
US20050124666A1 (en) * 2003-11-13 2005-06-09 Aventis Pharma Deutschland Gmbh Pentafluorosulfanylbenzoylguanidines, process for their preparation, use as a medicament or diagnostic aid, and medicament comprising same
EP4010433A1 (en) 2019-08-07 2022-06-15 Abbott Laboratories Chemiluminescent compounds for multiplexing

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3780027A (en) * 1970-04-29 1973-12-18 Merck & Co Inc Anthranilic acid derivatives
DE3929582A1 (de) * 1989-09-06 1991-03-07 Hoechst Ag Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament
ES2089600T3 (es) * 1992-02-15 1996-10-01 Hoechst Ag Benzoilguanidina sustituida en 3,5, con efecto antiarritmico y efecto inhibidor de la proliferacion de celulas.
ATE157351T1 (de) * 1993-02-20 1997-09-15 Hoechst Ag Substituierte benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament, als inhibitoren des zellulären na+/h+-austauschs oder als diagnostikum sowie sie enthaltendes medikament
DE4328869A1 (de) * 1993-08-27 1995-03-02 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19526381A1 (de) * 1995-07-19 1997-01-23 Hoechst Ag 4-Fluoralkyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
MX9602841A (es) 1997-01-31
IL118887A0 (en) 1996-10-31
ES2170183T3 (es) 2002-08-01
TW462960B (en) 2001-11-11
BR9603112A (pt) 1998-05-05
KR970006282A (ko) 1997-02-19
PT754680E (pt) 2002-06-28
HUP9601976A2 (en) 1997-09-29
AU6056396A (en) 1997-01-23
NZ299015A (en) 1997-08-22
AR003461A1 (es) 1998-08-05
IL118887A (en) 2002-07-25
PL314278A1 (en) 1997-01-20
AU704649B2 (en) 1999-04-29
TR199600588A2 (tr) 1997-03-21
CN1072644C (zh) 2001-10-10
HUP9601976A3 (en) 1998-07-28
HRP960343B1 (en) 2002-02-28
SK93896A3 (en) 1997-05-07
CZ212096A3 (en) 1997-04-16
SK281604B6 (sk) 2001-05-10
US6156800A (en) 2000-12-05
CZ291240B6 (cs) 2003-01-15
CN1143076A (zh) 1997-02-19
NO962999L (no) 1997-01-20
ATE211463T1 (de) 2002-01-15
NO306612B1 (no) 1999-11-29
DE59608533D1 (de) 2002-02-07
EP0754680B1 (de) 2002-01-02
RU2165412C2 (ru) 2001-04-20
DE19526381A1 (de) 1997-01-23
CA2181515A1 (en) 1997-01-20
HU9601976D0 (en) 1996-09-30
PL183906B1 (pl) 2002-07-31
HRP960343A2 (en) 1998-02-28
SI0754680T1 (en) 2002-04-30
EP0754680A1 (de) 1997-01-22
JPH0931045A (ja) 1997-02-04
NO962999D0 (no) 1996-07-18
ZA966106B (en) 1997-02-03

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