DK401988A - 11-substituerede 5-aryl-5h,11h-pyrrolo(2,1-c)-(1,4)benzoxazepiner, fremgangsmaade til deres fremstilling samt deres anvendelse som laegemidler - Google Patents

11-substituerede 5-aryl-5h,11h-pyrrolo(2,1-c)-(1,4)benzoxazepiner, fremgangsmaade til deres fremstilling samt deres anvendelse som laegemidler

Info

Publication number
DK401988A
DK401988A DK401988A DK401988A DK401988A DK 401988 A DK401988 A DK 401988A DK 401988 A DK401988 A DK 401988A DK 401988 A DK401988 A DK 401988A DK 401988 A DK401988 A DK 401988A
Authority
DK
Denmark
Prior art keywords
benzoxazepines
pyrrolo
medicines
aryl
procedures
Prior art date
Application number
DK401988A
Other languages
English (en)
Other versions
DK401988D0 (da
Inventor
Richard Charles Effland
Kevin James Kapples
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of DK401988D0 publication Critical patent/DK401988D0/da
Publication of DK401988A publication Critical patent/DK401988A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK401988A 1987-07-20 1988-07-19 11-substituerede 5-aryl-5h,11h-pyrrolo(2,1-c)-(1,4)benzoxazepiner, fremgangsmaade til deres fremstilling samt deres anvendelse som laegemidler DK401988A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/075,463 US4794110A (en) 1987-07-20 1987-07-20 5-Aryl-11-substituted-5H,11H-pyrrolo[2,1-c][1,4]benzoxazepined as analgesic and hypotensive agents

Publications (2)

Publication Number Publication Date
DK401988D0 DK401988D0 (da) 1988-07-19
DK401988A true DK401988A (da) 1989-01-21

Family

ID=22125924

Family Applications (1)

Application Number Title Priority Date Filing Date
DK401988A DK401988A (da) 1987-07-20 1988-07-19 11-substituerede 5-aryl-5h,11h-pyrrolo(2,1-c)-(1,4)benzoxazepiner, fremgangsmaade til deres fremstilling samt deres anvendelse som laegemidler

Country Status (5)

Country Link
US (1) US4794110A (da)
EP (1) EP0300356A1 (da)
JP (1) JPS6440486A (da)
DK (1) DK401988A (da)
PT (1) PT88022A (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5015637A (en) * 1990-05-25 1991-05-14 Hoechst-Roussel Pharmaceutical Inc. Pyrido[3,4-b]pyrrolo[1,2-e][1,4,5]oxadiazepines
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
CN103259027A (zh) 2005-04-28 2013-08-21 普罗透斯数字保健公司 药物信息系统
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(rap)-접합체 투여에 의한 간 질환의 치료
GB0711776D0 (en) * 2007-06-18 2007-07-25 Syngenta Participations Ag Substituted aromatic heterocyclic compounds as fungicides
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
TWI556839B (zh) 2009-05-06 2016-11-11 研究室護膚股份有限公司 包含活性劑-磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4045448A (en) * 1976-02-26 1977-08-30 American Hoechst Corporation Pyrrolo[2,1-c][1,4]benzoxazepine and benzoxazocine derivatives
US4169094A (en) * 1977-01-19 1979-09-25 American Hoechst Corporation Process for preparing aminoalkylpyrrolobenzoxazalkanes
US4608374A (en) * 1983-11-07 1986-08-26 Hoechst-Roussel Pharmaceuticals Inc. 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antipsychotic and analgesic agents
US4681879A (en) * 1983-11-07 1987-07-21 Hoechst-Roussel Pharmaceuticals Inc. 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antipsychotic and analgesic agents

Also Published As

Publication number Publication date
PT88022A (pt) 1989-06-30
EP0300356A1 (en) 1989-01-25
US4794110A (en) 1988-12-27
DK401988D0 (da) 1988-07-19
JPS6440486A (en) 1989-02-10

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