US6090925A
(en)
|
1993-03-09 |
2000-07-18 |
Epic Therapeutics, Inc. |
Macromolecular microparticles and methods of production and use
|
US5981719A
(en)
|
1993-03-09 |
1999-11-09 |
Epic Therapeutics, Inc. |
Macromolecular microparticles and methods of production and use
|
US5359030A
(en)
*
|
1993-05-10 |
1994-10-25 |
Protein Delivery, Inc. |
Conjugation-stabilized polypeptide compositions, therapeutic delivery and diagnostic formulations comprising same, and method of making and using the same
|
US5681811A
(en)
*
|
1993-05-10 |
1997-10-28 |
Protein Delivery, Inc. |
Conjugation-stabilized therapeutic agent compositions, delivery and diagnostic formulations comprising same, and method of making and using the same
|
KR100361933B1
(ko)
|
1993-09-08 |
2003-02-14 |
라 졸라 파마슈티칼 컴파니 |
화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트
|
DE4437502A1
(de)
*
|
1993-12-02 |
1995-06-08 |
Basf Ag |
Hirudin-Konjugate aus Hirudin und lipophilen Verbindungen
|
US5567592A
(en)
*
|
1994-02-02 |
1996-10-22 |
Regents Of The University Of California |
Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal
|
RU2066551C1
(ru)
*
|
1994-03-23 |
1996-09-20 |
Институт нефтехимического синтеза РАН |
Способ получения инсулинсодержащих полимерных гидрогелей
|
EP0761683B1
(en)
*
|
1994-05-20 |
2005-02-02 |
Hisamitsu Pharmaceutical Co., Inc. |
Protein or polypeptide, process for producing the same, and intermediate compound tehrefor
|
US5932462A
(en)
*
|
1995-01-10 |
1999-08-03 |
Shearwater Polymers, Inc. |
Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
|
US6251856B1
(en)
|
1995-03-17 |
2001-06-26 |
Novo Nordisk A/S |
Insulin derivatives
|
US5869602A
(en)
*
|
1995-03-17 |
1999-02-09 |
Novo Nordisk A/S |
Peptide derivatives
|
US6004583A
(en)
*
|
1995-03-22 |
1999-12-21 |
Orex Pharmaceutical Development Corp. |
Protein-containing polymer composition for oral administration
|
CA2279675A1
(en)
*
|
1995-12-15 |
1997-06-16 |
Enzo Therapeutics, Inc. |
Property effecting and/or property exhibiting constructs for localizing a nucleic acid construct within a cell for therapeutic and diagnostic uses
|
TW517067B
(en)
*
|
1996-05-31 |
2003-01-11 |
Hoffmann La Roche |
Interferon conjugates
|
EP0918543B1
(en)
*
|
1996-08-02 |
2004-04-21 |
Orex Pharmaceutical Development Corp. |
Polymer composition for oral administration of peptides and proteins
|
US6503881B2
(en)
*
|
1996-08-21 |
2003-01-07 |
Micrologix Biotech Inc. |
Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics
|
US6180604B1
(en)
*
|
1996-08-21 |
2001-01-30 |
Micrologix Biotech Inc. |
Compositions and methods for treating infections using analogues of indolicidin
|
US6072040A
(en)
*
|
1996-10-15 |
2000-06-06 |
Medical Analysis Systems, Inc. |
Stabilized conjugates of uncomplexed subunits of multimeric proteins
|
US6132712A
(en)
*
|
1996-12-11 |
2000-10-17 |
A. Glenn Braswell |
Superoxide dismutase stabilized with fragments of casein and pharmaceutical compositions incorporating same
|
US6416778B1
(en)
|
1997-01-24 |
2002-07-09 |
Femmepharma |
Pharmaceutical preparations and methods for their regional administration
|
US5993856A
(en)
*
|
1997-01-24 |
1999-11-30 |
Femmepharma |
Pharmaceutical preparations and methods for their administration
|
US5804183A
(en)
*
|
1997-01-31 |
1998-09-08 |
Enzon, Inc. |
Arginine deminase derived from mycoplasma arthritidis and polymer conjugates containing the same
|
US20040009166A1
(en)
*
|
1997-04-30 |
2004-01-15 |
Filpula David R. |
Single chain antigen-binding polypeptides for polymer conjugation
|
EP0981548A4
(en)
*
|
1997-04-30 |
2005-11-23 |
Enzon Inc |
SINGLE CHAIN PROTEINS FIXING ANTIGENS CAPABLE OF GLYCOSYLATION, PRODUCTION AND USES THEREOF
|
US6583267B2
(en)
*
|
1997-06-06 |
2003-06-24 |
Kyowa Hakko Kogyo Co., Ltd. |
Chemically modified polypeptides
|
IS4518A
(is)
*
|
1997-07-09 |
1999-01-10 |
Lyfjathroun Hf, The Icelandic Bio Pharmaceutical Group |
Nýtt lyfjaform fyrir bóluefni
|
US6165458A
(en)
*
|
1997-12-26 |
2000-12-26 |
Pharmaderm Laboratories Ltd. |
Composition and method for dermal and transdermal administration of a cytokine
|
AU3247799A
(en)
*
|
1998-02-27 |
1999-09-15 |
Novo Nordisk A/S |
Glp-1 derivatives of glp-1 and exendin with protracted profile of action
|
WO1999043707A1
(en)
*
|
1998-02-27 |
1999-09-02 |
Novo Nordisk A/S |
N-terminally modified glp-1 derivatives
|
KR19990085365A
(ko)
*
|
1998-05-16 |
1999-12-06 |
허영섭 |
지속적으로 약물 조절방출이 가능한 생분해성 고분자 미립구 및그 제조방법
|
PL192364B1
(pl)
*
|
1998-06-08 |
2006-10-31 |
Hoffmann La Roche |
Zastosowanie koniugatu PEG-IFN-α 2A w połączeniu z rybawiryną
|
US6703381B1
(en)
*
|
1998-08-14 |
2004-03-09 |
Nobex Corporation |
Methods for delivery therapeutic compounds across the blood-brain barrier
|
ATE327254T1
(de)
*
|
1998-10-16 |
2006-06-15 |
Biogen Idec Inc |
Interferon-beta fusionsproteine und deren verwendungen
|
IL142282A0
(en)
*
|
1998-10-16 |
2002-03-10 |
Biogen Inc |
Compositions containing polymer conjugates of interferon-beta-1a
|
US6333396B1
(en)
|
1998-10-20 |
2001-12-25 |
Enzon, Inc. |
Method for targeted delivery of nucleic acids
|
US6458953B1
(en)
*
|
1998-12-09 |
2002-10-01 |
La Jolla Pharmaceutical Company |
Valency platform molecules comprising carbamate linkages
|
CN1762990A
(zh)
*
|
1999-06-08 |
2006-04-26 |
拉卓拉药物公司 |
包含氨基氧基的化合价平台分子
|
US6209490B1
(en)
*
|
1999-06-17 |
2001-04-03 |
Gary J. Schwede |
Living quarters container for cats or ferrets
|
US7169889B1
(en)
|
1999-06-19 |
2007-01-30 |
Biocon Limited |
Insulin prodrugs hydrolyzable in vivo to yield peglylated insulin
|
US6309633B1
(en)
*
|
1999-06-19 |
2001-10-30 |
Nobex Corporation |
Amphiphilic drug-oligomer conjugates with hydroyzable lipophile components and methods for making and using the same
|
CZ299516B6
(cs)
*
|
1999-07-02 |
2008-08-20 |
F. Hoffmann-La Roche Ag |
Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem
|
JO2291B1
(en)
|
1999-07-02 |
2005-09-12 |
اف . هوفمان لاروش ايه جي |
Erythropoietin derivatives
|
KR100345214B1
(ko)
*
|
1999-08-17 |
2002-07-25 |
이강춘 |
생체적합성 고분자가 수식된 펩타이드의 비점막 전달
|
US6323311B1
(en)
*
|
1999-09-22 |
2001-11-27 |
University Of Utah Research Foundation |
Synthesis of insulin derivatives
|
CA2385533C
(en)
*
|
1999-10-04 |
2008-03-25 |
Shearwater Corporation |
Polymer stabilized neuropeptides
|
RU2155602C1
(ru)
|
1999-11-30 |
2000-09-10 |
Оао "Куантум Сатис" |
Инсулинсодержащее лекарственное средство для перорального применения и способ его получения
|
US6638906B1
(en)
*
|
1999-12-13 |
2003-10-28 |
Nobex Corporation |
Amphiphilic polymers and polypeptide conjugates comprising same
|
CA2395254C
(en)
|
1999-12-24 |
2010-05-11 |
Kyowa Hakko Kogyo Co., Ltd. |
Branched polyalkylene glycols
|
AU4267700A
(en)
*
|
2000-01-13 |
2001-07-19 |
Academia Sinica |
Application of somatostatin analogs to specific delivery of anti-tumor drugs into tumor cells
|
KR100890125B1
(ko)
|
2000-02-24 |
2009-03-24 |
일라이 릴리 앤드 캄파니 |
소마토트로핀의 지속적인 방출을 위한 비수성 주사제제들
|
EP1292337A2
(en)
|
2000-06-08 |
2003-03-19 |
La Jolla Pharmaceutical |
Multivalent platform molecules comprising high molecular weight polyethylene oxide
|
AU2001271491A1
(en)
|
2000-06-26 |
2002-01-08 |
Monsanto Technology Llc |
Non-aqueous surfactant-containing formulations for extended release of somatotropin
|
US6664234B1
(en)
|
2000-06-30 |
2003-12-16 |
Monsanto Technology Llc |
Non-aqueous injectable formulation preparation with pH adjusted for extended release of somatotropin
|
US7105154B2
(en)
*
|
2000-07-19 |
2006-09-12 |
Pepgen Corporation |
Method of treatment using interferon-tau
|
JP2004508338A
(ja)
*
|
2000-09-08 |
2004-03-18 |
グリフォン セラピューティクス,インコーポレーテッド |
ポリマー修飾合成タンパク質
|
CN1406131A
(zh)
*
|
2000-12-25 |
2003-03-26 |
株式会社资生堂 |
活化交感神经的香料组合物
|
US7060675B2
(en)
|
2001-02-15 |
2006-06-13 |
Nobex Corporation |
Methods of treating diabetes mellitus
|
US6867183B2
(en)
|
2001-02-15 |
2005-03-15 |
Nobex Corporation |
Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
|
US6538104B2
(en)
|
2001-04-27 |
2003-03-25 |
Medical Analysis Systems, Inc. |
Stabilization of cardiac troponin I subunits and complexes
|
EP1392339A4
(en)
*
|
2001-05-04 |
2009-05-27 |
Univ North Carolina State |
POLYMER CONJUGATES OF INSECTICIDES, PEPTIDES OR NUCLEIC ACIDS AND METHOD OF USE THEREOF
|
US20030108585A1
(en)
*
|
2001-05-04 |
2003-06-12 |
Roe R. Michael |
Polymer conjugates of insecticidal peptides or nucleic acids or insecticides and methods of use thereof
|
MXPA03010649A
(es)
|
2001-05-21 |
2005-10-05 |
Nektar Therapeutics |
Administracion pulmonar de insulina modificada quimicamente.
|
WO2002096977A1
(fr)
*
|
2001-05-30 |
2002-12-05 |
Nanocarrier Co., Ltd. |
Procede de liaison d'une substance a incorporer a une terminaison polymere
|
US7713932B2
(en)
*
|
2001-06-04 |
2010-05-11 |
Biocon Limited |
Calcitonin drug-oligomer conjugates, and uses thereof
|
US6713452B2
(en)
|
2001-06-04 |
2004-03-30 |
Nobex Corporation |
Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
|
US6828297B2
(en)
*
|
2001-06-04 |
2004-12-07 |
Nobex Corporation |
Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
|
US6835802B2
(en)
*
|
2001-06-04 |
2004-12-28 |
Nobex Corporation |
Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties
|
US6858580B2
(en)
*
|
2001-06-04 |
2005-02-22 |
Nobex Corporation |
Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
|
US6828305B2
(en)
*
|
2001-06-04 |
2004-12-07 |
Nobex Corporation |
Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
|
US7008650B2
(en)
*
|
2001-08-09 |
2006-03-07 |
Lam Paul Y S |
Compositions for the treatment of acquired immunodeficiency disease
|
US6835536B2
(en)
|
2001-08-21 |
2004-12-28 |
Micrologix Biotech Inc. |
Antimicrobial cationic peptides and formulations thereof
|
US8933029B2
(en)
|
2001-08-24 |
2015-01-13 |
Carrus Capital Corporation |
Antimicrobial and anti-inflammatory peptides
|
US6770625B2
(en)
|
2001-09-07 |
2004-08-03 |
Nobex Corporation |
Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith
|
US7312192B2
(en)
|
2001-09-07 |
2007-12-25 |
Biocon Limited |
Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
|
US6913903B2
(en)
|
2001-09-07 |
2005-07-05 |
Nobex Corporation |
Methods of synthesizing insulin polypeptide-oligomer conjugates, and proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
|
US7196059B2
(en)
|
2001-09-07 |
2007-03-27 |
Biocon Limited |
Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
|
US7166571B2
(en)
|
2001-09-07 |
2007-01-23 |
Biocon Limited |
Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
|
US7030082B2
(en)
*
|
2001-09-07 |
2006-04-18 |
Nobex Corporation |
Pharmaceutical compositions of drug-oligomer conjugates and methods of treating disease therewith
|
ATE446971T1
(de)
*
|
2001-09-07 |
2009-11-15 |
Biocon Ltd |
Verfahren zur synthese von insulinpolypeptid- oligomer-konjugaten und proinsulinpolypeptid- oligomer-konjugaten und verfahren zu deren synthese
|
MXPA04004336A
(es)
|
2001-11-07 |
2005-05-16 |
Nektar Therapeutics Al Corp |
Polimeros ramificados y sus conjugados.
|
US20030171285A1
(en)
*
|
2001-11-20 |
2003-09-11 |
Finn Rory F. |
Chemically-modified human growth hormone conjugates
|
JP2005513080A
(ja)
*
|
2001-12-20 |
2005-05-12 |
フェムファーマ, インコーポレイテッド |
薬物の膣送達
|
EP1476191A2
(en)
*
|
2002-01-16 |
2004-11-17 |
Pepgen Corporation |
Oral administration of interferon-tau
|
DK3025726T3
(da)
|
2002-01-18 |
2019-12-09 |
Biogen Ma Inc |
Polyalkylenpolymerforbindelser og anvendelser deraf
|
EA200401565A1
(ru)
*
|
2002-05-24 |
2005-04-28 |
Неофарм, Инк. |
Способ получения кардиолипина или аналога кардиолипина (варианты), способ получения липосомы и композиция кардиолипина для лечения заболеваний (варианты)
|
CA2486967A1
(en)
*
|
2002-05-24 |
2003-12-04 |
Neopharm, Inc. |
Cardiolipin compositions their methods of preparation and use
|
US7601688B2
(en)
*
|
2002-06-13 |
2009-10-13 |
Biocon Limited |
Methods of reducing hypoglycemic episodes in the treatment of diabetes mellitus
|
US7459435B2
(en)
*
|
2002-08-29 |
2008-12-02 |
Hoffmann-La Roche Inc. |
Treatment of disturbances of iron distribution
|
CA2497777A1
(en)
*
|
2002-09-05 |
2004-03-18 |
The General Hospital Corporation |
Modified asialo-interferons and uses thereof
|
US20050277611A1
(en)
*
|
2002-10-16 |
2005-12-15 |
Neopharm, Inc. |
Cationic cardiolipin analoges and its use thereof
|
US20040152769A1
(en)
*
|
2002-11-09 |
2004-08-05 |
Ekwuribe Nnochiri Nkem |
Modified carbamate-containing prodrugs and methods of synthesizing same
|
US7459436B2
(en)
*
|
2002-11-22 |
2008-12-02 |
Hoffmann-La Roche Inc. |
Treatment of disturbances of iron distribution
|
US7648962B2
(en)
*
|
2002-11-26 |
2010-01-19 |
Biocon Limited |
Natriuretic compounds, conjugates, and uses thereof
|
SG159387A1
(en)
*
|
2002-11-26 |
2010-03-30 |
Biocon Ltd In |
Modified natriuretic compounds, conjugates, and uses thereof
|
WO2004060387A1
(en)
*
|
2002-12-27 |
2004-07-22 |
Diobex, Inc. |
Compositions and methods for the prevention and control of insulin-induced hypoglycemia
|
US7655618B2
(en)
|
2002-12-27 |
2010-02-02 |
Diobex, Inc. |
Compositions and methods for the prevention and control of insulin-induced hypoglycemia
|
US9173836B2
(en)
|
2003-01-02 |
2015-11-03 |
FemmeParma Holding Company, Inc. |
Pharmaceutical preparations for treatments of diseases and disorders of the breast
|
AU2004203700B2
(en)
*
|
2003-01-02 |
2007-06-21 |
Femmepharma Holding Company, Inc. |
Pharmaceutical preparations for treatments of diseases and disorders of the breast
|
US7074755B2
(en)
*
|
2003-05-17 |
2006-07-11 |
Centocor, Inc. |
Erythropoietin conjugate compounds with extended half-lives
|
EP1641481A4
(en)
*
|
2003-05-30 |
2008-10-15 |
Centocor Inc |
TRAINING OF NEW ERYTHROPOIETIN CONJUGATES USING TRANSGLUTAMINASE
|
US20060078560A1
(en)
*
|
2003-06-23 |
2006-04-13 |
Neopharm, Inc. |
Method of inducing apoptosis and inhibiting cardiolipin synthesis
|
AU2004262906B2
(en)
|
2003-07-23 |
2008-04-03 |
Nordic Bioscience A/S |
Use of calcitonin in osteoarthritis
|
US7635675B2
(en)
|
2003-08-13 |
2009-12-22 |
Biocon Limited |
Micro-particle fatty acid salt solid dosage formulations for therapeutic agents
|
JP2007514673A
(ja)
*
|
2003-12-19 |
2007-06-07 |
エフ.ホフマン−ラ ロシュ アーゲー |
慢性炎症性腸疾患の際の鉄分布障害の処置におけるエリスロポエチンの使用
|
US20050136121A1
(en)
*
|
2003-12-22 |
2005-06-23 |
Shear/Kershman Laboratories, Inc. |
Oral peptide delivery system with improved bioavailability
|
SE0401942D0
(sv)
*
|
2004-07-28 |
2004-07-28 |
Lipopeptide Ab |
New antimicrobial peptide complexes
|
WO2005115477A2
(en)
|
2004-04-13 |
2005-12-08 |
Quintessence Biosciences, Inc. |
Non-natural ribonuclease conjugates as cytotoxic agents
|
US8329958B2
(en)
|
2004-07-02 |
2012-12-11 |
Biocon Limited |
Combinatorial synthesis of PEG oligomer libraries
|
UA103758C2
(ru)
*
|
2004-07-19 |
2013-11-25 |
Биокон Лимитед |
Конъюгаты олигомеров инсулина, их композиции и применение
|
US20100048454A1
(en)
*
|
2004-08-03 |
2010-02-25 |
Emisphere Technologies, Inc. |
Antidiabetic oral insulin-biguanide combination
|
TW200612993A
(en)
*
|
2004-10-08 |
2006-05-01 |
Alza Corp |
Lipopolymer conjugates
|
US20080207505A1
(en)
*
|
2005-01-12 |
2008-08-28 |
James Kenneth D |
Bna Conjugates and Methods of Use
|
WO2006079641A2
(en)
*
|
2005-01-27 |
2006-08-03 |
Novo Nordisk A/S |
Insulin derivatives conjugated with structurally well defined branched polymers
|
WO2006082205A1
(en)
*
|
2005-02-02 |
2006-08-10 |
Novo Nordisk A/S |
Insulin derivatives
|
ATE496941T1
(de)
*
|
2005-07-08 |
2011-02-15 |
Biocon Ltd |
Herstellung von insulinkonjugaten
|
EP1926768B1
(en)
|
2005-07-18 |
2011-09-14 |
Nektar Therapeutics |
Branched functionalized polymers using branched polyol cores
|
CN101291952B
(zh)
*
|
2005-10-13 |
2016-02-03 |
拜奥康有限公司 |
制备胰岛素缀合物的方法
|
ES2572952T3
(es)
|
2005-11-07 |
2016-06-03 |
Indiana University Research And Technology Corporation |
Análogos de glucagón que muestran solubilidad y estabilidad fisiológicas
|
AU2006318815B2
(en)
|
2005-11-17 |
2010-08-19 |
Novartis Ag |
Pharmaceutical composition
|
GB0604187D0
(en)
*
|
2006-03-02 |
2006-04-12 |
Fusion Antibodies Ltd |
Peptide and uses thereof
|
WO2007115175A2
(en)
*
|
2006-03-30 |
2007-10-11 |
Palatin Technologies, Inc. |
Cyclic natriuretic peptide constructs
|
US8580746B2
(en)
*
|
2006-03-30 |
2013-11-12 |
Palatin Technologies, Inc. |
Amide linkage cyclic natriuretic peptide constructs
|
WO2007115182A2
(en)
*
|
2006-03-30 |
2007-10-11 |
Palatin Technologies, Inc. |
Linear natriuretic peptide constructs
|
ES2548393T3
(es)
*
|
2006-05-09 |
2015-10-16 |
Novo Nordisk A/S |
Derivado de insulina
|
WO2007139941A2
(en)
|
2006-05-26 |
2007-12-06 |
Amylin Pharmaceuticals, Inc. |
Composition and methods for treatment of congestive heart failure
|
GB0611405D0
(en)
*
|
2006-06-09 |
2006-07-19 |
Univ Belfast |
FKBP-L: A novel inhibitor of angiogenesis
|
US8840882B2
(en)
*
|
2006-06-23 |
2014-09-23 |
Quintessence Biosciences, Inc. |
Modified ribonucleases
|
JP2009543868A
(ja)
|
2006-07-17 |
2009-12-10 |
クインテセンス バイオサイエンシーズ インコーポレーティッド |
癌治療に関する方法および組成物
|
JP5550338B2
(ja)
*
|
2006-07-31 |
2014-07-16 |
ノボ・ノルデイスク・エー/エス |
ペグ化持続型インスリン
|
WO2008019147A2
(en)
*
|
2006-08-04 |
2008-02-14 |
Amylin Pharmaceuticals, Inc. |
Use of exendins, exendin agonists and glp-1 receptor agonists for altering the concentration of fibrinogen
|
CN101541830A
(zh)
*
|
2006-09-22 |
2009-09-23 |
诺沃-诺迪斯克有限公司 |
蛋白酶抗性的胰岛素类似物
|
US7807143B2
(en)
*
|
2006-10-18 |
2010-10-05 |
Research Development Foundation |
Alpha-MSH therapies for treatment of autoimmune disease
|
US20080153789A1
(en)
*
|
2006-12-26 |
2008-06-26 |
Femmepharma Holding Company, Inc. |
Topical administration of danazol
|
WO2008086086A2
(en)
*
|
2007-01-05 |
2008-07-17 |
Indiana University Research And Technology Corporation |
Glucagon analogs exhibiting enhanced solubility in physiological ph buffers
|
CA2677932A1
(en)
|
2007-02-15 |
2008-08-21 |
Indiana University Research And Technology Corporation |
Glucagon/glp-1 receptor co-agonists
|
ES2563038T3
(es)
*
|
2007-04-30 |
2016-03-10 |
Novo Nordisk A/S |
Método para secar una composición proteica, una composición proteica seca y una composición farmacéutica que comprende la proteína seca
|
JP5675347B2
(ja)
*
|
2007-06-01 |
2015-02-25 |
ノボ・ノルデイスク・エー/エス |
安定した非水性薬学的組成物
|
WO2009017662A2
(en)
*
|
2007-07-27 |
2009-02-05 |
Immuneregen Biosciences, Inc. |
Method of using substance p analogs for treatment amelioration of myelodysplastic syndrome
|
US8697062B2
(en)
*
|
2007-10-08 |
2014-04-15 |
Quintessence Biosciences, Inc. |
Compositions and methods for ribonuclease-based therapeutics
|
BRPI0818004B8
(pt)
|
2007-10-16 |
2021-05-25 |
Biocon Ltd |
composição farmacêutica sólida administrável por via oral e o processo da mesma.
|
CA2707861A1
(en)
|
2007-10-30 |
2009-05-07 |
Indiana University Research And Technology Corporation |
Glucagon antagonists
|
MX2010004298A
(es)
*
|
2007-10-30 |
2010-05-03 |
Univ Indiana Res & Tech Corp |
Compuestos que exhiben actividad antagonista de glucagon y agonista de glp-1.
|
WO2009099763A1
(en)
*
|
2008-01-30 |
2009-08-13 |
Indiana University Research And Technology Corporation |
Ester-based peptide prodrugs
|
ES2618073T3
(es)
*
|
2008-03-14 |
2017-06-20 |
Novo Nordisk A/S |
Análogos de insulina estabilizados frente a proteasas
|
EP2910571B1
(en)
|
2008-03-18 |
2016-10-05 |
Novo Nordisk A/S |
Protease stabilized, acylated insulin analogues
|
US20090271021A1
(en)
*
|
2008-04-28 |
2009-10-29 |
Popp Shane M |
Execution system for the monitoring and execution of insulin manufacture
|
PE20100255A1
(es)
|
2008-06-17 |
2010-04-25 |
Univ Indiana Res & Tech Corp |
Co-agonistas del receptor de glucagon/glp-1
|
CN102105159B
(zh)
*
|
2008-06-17 |
2015-07-08 |
印第安纳大学研究及科技有限公司 |
基于gip的混合激动剂用于治疗代谢紊乱和肥胖症
|
US8450270B2
(en)
*
|
2008-06-17 |
2013-05-28 |
Indiana University Research And Technology Corporation |
Glucagon analogs exhibiting enhanced solubility and stability in physiological pH buffers
|
WO2010015668A1
(en)
*
|
2008-08-06 |
2010-02-11 |
Novo Nordisk A/S |
Conjugated proteins with prolonged in vivo efficacy
|
US20110171312A1
(en)
*
|
2008-09-19 |
2011-07-14 |
Nektar Therapeutics |
Modified therapeutic peptides, methods of their preparation and use
|
EP2341942A1
(en)
|
2008-09-19 |
2011-07-13 |
Nektar Therapeutics |
Polymer conjugates of therapeutic peptides
|
JP2012504423A
(ja)
|
2008-10-01 |
2012-02-23 |
クインテッセンス バイオサイエンシズ,インコーポレーテッド |
治療用リボヌクレアーゼ
|
CN102256992B
(zh)
|
2008-12-19 |
2015-04-22 |
印第安纳大学研究及科技有限公司 |
胰岛素类似物
|
BRPI0922969A2
(pt)
|
2008-12-19 |
2019-09-24 |
Univ Indiana Res & Tech Corp |
pró-farmaco de amida baseado na superfamília de glucagon peptídeo.
|
EP2376521B1
(en)
|
2008-12-19 |
2016-04-13 |
Indiana University Research and Technology Corporation |
Amide-based insulin prodrugs
|
AU2010207725B2
(en)
|
2009-01-22 |
2015-06-11 |
Novo Nordisk Health Care Ag |
Stable growth hormone compounds
|
WO2010096394A2
(en)
|
2009-02-17 |
2010-08-26 |
Redwood Biosciences, Inc. |
Aldehyde-tagged protein-based drug carriers and methods of use
|
MX2011009559A
(es)
|
2009-03-12 |
2012-01-12 |
Nordic Bioscience As |
Tratamiento de la diabetes y el sindrome metabolico.
|
IN2012DN00377A
(da)
|
2009-06-16 |
2015-08-21 |
Univ Indiana Res & Tech Corp |
|
WO2011003633A1
(en)
|
2009-07-06 |
2011-01-13 |
Alize Pharma Ii |
Pegylated l-asparaginase
|
US20110003000A1
(en)
*
|
2009-07-06 |
2011-01-06 |
Femmepharma Holding Company, Inc. |
Transvaginal Delivery of Drugs
|
HUP0900482A2
(en)
|
2009-08-03 |
2011-03-28 |
Cera Med Kft |
Pharmaceutical formulation for oral administration
|
US8841249B2
(en)
|
2009-08-06 |
2014-09-23 |
Novo Nordisk A/S |
Growth hormones with prolonged in-vivo efficacy
|
CA2776302A1
(en)
*
|
2009-10-13 |
2011-04-21 |
F. Hoffmann-La Roche Ag |
Neuropeptide-2 receptor (y-2r) agonists
|
EP2512503A4
(en)
|
2009-12-18 |
2013-08-21 |
Univ Indiana Res & Tech Corp |
COAGONISTS OF GLUCAGON / GLP-1 RECEPTOR
|
US20120283171A1
(en)
|
2009-12-21 |
2012-11-08 |
Ambrx, Inc. |
Modified bovine somatotropin polypeptides and their uses
|
SG181769A1
(en)
|
2009-12-21 |
2012-07-30 |
Ambrx Inc |
Modified porcine somatotropin polypeptides and their uses
|
AU2011208625C1
(en)
|
2010-01-22 |
2022-08-18 |
Novo Nordisk Health Care Ag |
Growth hormones with prolonged in-vivo efficacy
|
CA2787895A1
(en)
|
2010-01-22 |
2011-07-28 |
Novo Nordisk Health Care Ag |
Stable growth hormone compounds
|
MX2012008603A
(es)
|
2010-01-27 |
2013-01-25 |
Univ Indiana Res & Tech Corp |
Conjugados de antagonista de glucagon-agonista de gip y composiciones para el tratamiento de desordenes metabolicos y obesidad.
|
CA2797089A1
(en)
|
2010-05-13 |
2011-11-17 |
Indiana University Research And Technology Corporation |
Glucagon superfamily peptides exhibiting g protein-coupled receptor activity
|
ES2661228T3
(es)
|
2010-05-13 |
2018-03-28 |
Indiana University Research And Technology Corporation |
Péptidos de la superfamilia de glucagón que muestran actividad de receptor nuclear de hormona
|
WO2011159895A2
(en)
|
2010-06-16 |
2011-12-22 |
Indiana University Research And Technology Corporation |
Single chain insulin agonists exhibiting high activity at the insulin receptor
|
RU2580317C2
(ru)
|
2010-06-24 |
2016-04-10 |
Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн |
Пептидные пролекарства, принадлежащие к суперсемейству амид-содержащих глюкагонов
|
JP5912112B2
(ja)
|
2010-06-24 |
2016-04-27 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation |
アミド系インスリンプロドラッグ
|
WO2012088116A2
(en)
|
2010-12-22 |
2012-06-28 |
Indiana University Research And Technology Corporation |
Glucagon analogs exhibiting gip receptor activity
|
KR20140016262A
(ko)
|
2011-01-14 |
2014-02-07 |
레드우드 바이오사이언스 인코포레이티드 |
알데하이드-태깅된 면역글로불린 폴리펩타이드 및 이의 사용 방법
|
DK2723367T3
(da)
|
2011-06-22 |
2017-07-17 |
Univ Indiana Res & Tech Corp |
Glucagon/glp-1-receptor-co-agonister
|
BR112013032717A2
(pt)
|
2011-06-22 |
2017-01-24 |
Univ Indiana Res & Tech Corp |
coagonistas do receptor de glucagon/glp-1
|
AU2012301793A1
(en)
*
|
2011-08-30 |
2014-03-20 |
Quanta Biodesign, Ltd. |
Branched discrette PEG constructs
|
HUE039105T2
(hu)
|
2011-11-02 |
2018-12-28 |
Keybioscience Ag |
Kalcitonin mimetikumok betegségek és rendellenességek kezelésére
|
KR102019911B1
(ko)
|
2011-11-02 |
2019-09-09 |
키바이오사이언스 아게 |
질병 및 장애 치료용 펩타이드 유사체
|
WO2013074910A1
(en)
|
2011-11-17 |
2013-05-23 |
Indiana University Research And Technology Corporation |
Glucagon superfamily peptides exhibiting glucocorticoid receptor activity
|
EP2793932B1
(en)
|
2011-12-20 |
2018-10-03 |
Indiana University Research and Technology Corporation |
Ctp-based insulin analogs for treatment of diabetes
|
US9107904B2
(en)
*
|
2012-04-05 |
2015-08-18 |
Massachusetts Institute Of Technology |
Immunostimulatory compositions and methods of use thereof
|
CA2870313A1
(en)
|
2012-04-11 |
2013-10-17 |
Novo Nordisk A/S |
Insulin formulations
|
TWI599575B
(zh)
|
2012-06-21 |
2017-09-21 |
印第安納大學科技研究公司 |
表現gip受體活性之胰高血糖素類似物
|
EP3395358B1
(en)
|
2012-09-26 |
2019-11-06 |
Indiana University Research and Technology Corporation |
Insulin analog dimers
|
JP6538645B2
(ja)
|
2013-03-14 |
2019-07-03 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation |
インスリン‐インクレチン複合物
|
US11045523B2
(en)
|
2013-04-05 |
2021-06-29 |
Novo Nordisk Healthcare Ag |
Formulation of growth hormone albumin-binder conjugate
|
RU2015151135A
(ru)
*
|
2013-04-30 |
2017-06-02 |
Массачусетс Инститьют Оф Текнолоджи |
Инъекционные гелевые нанокаркасы для лечения диабета
|
PT3004138T
(pt)
|
2013-06-05 |
2024-06-18 |
Bausch Health Ireland Ltd |
Agonistas ultrapuros de guanilato ciclase c, método de produção e utilização dos mesmos
|
WO2015052088A1
(en)
|
2013-10-07 |
2015-04-16 |
Novo Nordisk A/S |
Novel derivative of an insulin analogue
|
US10232021B2
(en)
|
2013-11-14 |
2019-03-19 |
Keybioscience Ag |
Calcitonin mimetics for treating diseases and disorders
|
WO2016049174A1
(en)
|
2014-09-24 |
2016-03-31 |
Indiana University Research And Technology Corporation |
Lipidated amide-based insulin prodrugs
|
US10232020B2
(en)
|
2014-09-24 |
2019-03-19 |
Indiana University Research And Technology Corporation |
Incretin-insulin conjugates
|
CA2967649A1
(en)
*
|
2014-11-21 |
2016-05-26 |
The University Of Chicago |
Synthetic peptides
|
US10046058B2
(en)
|
2014-12-02 |
2018-08-14 |
Rezolute, Inc. |
Use of hydrophobic organic acids to increase hydrophobicity of proteins and protein conjugates
|
GB201500263D0
(en)
|
2015-01-08 |
2015-02-25 |
Keybioscience Ag |
Calcitonin analogues for treating diseases and disorders
|
US9375478B1
(en)
|
2015-01-30 |
2016-06-28 |
Par Pharmaceutical, Inc. |
Vasopressin formulations for use in treatment of hypotension
|
US9937223B2
(en)
|
2015-01-30 |
2018-04-10 |
Par Pharmaceutical, Inc. |
Vasopressin formulations for use in treatment of hypotension
|
US9925233B2
(en)
|
2015-01-30 |
2018-03-27 |
Par Pharmaceutical, Inc. |
Vasopressin formulations for use in treatment of hypotension
|
US9687526B2
(en)
|
2015-01-30 |
2017-06-27 |
Par Pharmaceutical, Inc. |
Vasopressin formulations for use in treatment of hypotension
|
US9750785B2
(en)
|
2015-01-30 |
2017-09-05 |
Par Pharmaceutical, Inc. |
Vasopressin formulations for use in treatment of hypotension
|
US9744209B2
(en)
|
2015-01-30 |
2017-08-29 |
Par Pharmaceutical, Inc. |
Vasopressin formulations for use in treatment of hypotension
|
CN107708679A
(zh)
|
2015-06-04 |
2018-02-16 |
安特里阿比奥有限公司 |
用于制备位点特异性蛋白质偶联物的胺聚乙二醇化方法
|
US11208632B2
(en)
|
2016-04-26 |
2021-12-28 |
R.P. Scherer Technologies, Llc |
Antibody conjugates and methods of making and using the same
|
MX2019006463A
(es)
|
2016-12-16 |
2019-08-14 |
Novo Nordisk As |
Composiciones farmaceuticas que contienen insulina.
|
US11806371B2
(en)
|
2017-01-19 |
2023-11-07 |
The University Of Chicago |
Oxalobacter formigenes (Of)-derived factors for the treatment of treatment/prevention of excess oxalate levels
|
GB201704429D0
(en)
|
2017-03-21 |
2017-05-03 |
Keybioscience Ag |
Calcitonin mimetics for treating diseases and disorders
|
GB201707955D0
(en)
|
2017-05-18 |
2017-07-05 |
Keybioscience Ag |
Dual amylin and calcitonin receptor agonists for treating diseases and disorders
|
US10174302B1
(en)
|
2017-06-21 |
2019-01-08 |
Xl-Protein Gmbh |
Modified L-asparaginase
|
US12016899B2
(en)
|
2018-07-18 |
2024-06-25 |
The University Of Chicago |
Compositions comprising Sel1-derived peptides and methods of treatment/prevention of excess oxalate levels and associated conditions/diseases therewith
|
GB201813677D0
(en)
|
2018-08-22 |
2018-10-03 |
Keybioscience Ag |
Calcitonin mimetics for treating diseases and disorders
|
GB201813678D0
(en)
|
2018-08-22 |
2018-10-03 |
Keybioscience Ag |
Acylated calcitonin mimetics
|