DK0692489T3 - Fremstilling af stabile zinkinsulinanalogkrystaller - Google Patents

Fremstilling af stabile zinkinsulinanalogkrystaller

Info

Publication number
DK0692489T3
DK0692489T3 DK95304098T DK95304098T DK0692489T3 DK 0692489 T3 DK0692489 T3 DK 0692489T3 DK 95304098 T DK95304098 T DK 95304098T DK 95304098 T DK95304098 T DK 95304098T DK 0692489 T3 DK0692489 T3 DK 0692489T3
Authority
DK
Denmark
Prior art keywords
preparation
insulin analog
zinc insulin
stable zinc
analog crystals
Prior art date
Application number
DK95304098T
Other languages
Danish (da)
English (en)
Inventor
Bruce Hill Frank
Jeffrey Clayton Baker
Nancy Delores Carter
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22990041&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0692489(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK0692489T3 publication Critical patent/DK0692489T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK95304098T 1994-06-16 1995-06-14 Fremstilling af stabile zinkinsulinanalogkrystaller DK0692489T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/260,647 US5504188A (en) 1994-06-16 1994-06-16 Preparation of stable zinc insulin analog crystals

Publications (1)

Publication Number Publication Date
DK0692489T3 true DK0692489T3 (da) 2003-03-31

Family

ID=22990041

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95304098T DK0692489T3 (da) 1994-06-16 1995-06-14 Fremstilling af stabile zinkinsulinanalogkrystaller

Country Status (29)

Country Link
US (1) US5504188A (enExample)
EP (1) EP0692489B1 (enExample)
JP (1) JP3595607B2 (enExample)
KR (1) KR100369951B1 (enExample)
CN (1) CN1184234C (enExample)
AT (1) ATE233278T1 (enExample)
AU (1) AU697794B2 (enExample)
BR (1) BR9502798A (enExample)
CA (1) CA2151563C (enExample)
CO (1) CO4410205A1 (enExample)
CZ (1) CZ286066B6 (enExample)
DE (1) DE69529708T2 (enExample)
DK (1) DK0692489T3 (enExample)
ES (1) ES2188637T3 (enExample)
FI (1) FI952930A7 (enExample)
HU (1) HUT73495A (enExample)
IL (1) IL114152A (enExample)
IN (1) IN178919B (enExample)
MY (1) MY130551A (enExample)
NO (1) NO952334L (enExample)
NZ (1) NZ272358A (enExample)
PE (1) PE21896A1 (enExample)
PL (1) PL180968B1 (enExample)
RO (1) RO113529B1 (enExample)
RU (1) RU2156257C2 (enExample)
SI (1) SI0692489T1 (enExample)
TW (1) TW379228B (enExample)
YU (1) YU39595A (enExample)
ZA (1) ZA954942B (enExample)

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AU1375199A (en) * 1997-11-12 1999-05-31 Alza Corporation Method for decreasing self-association of polypeptides
RU2205188C2 (ru) 1998-06-30 2003-05-27 Ново Нордиск А/С Затравочные кристаллы для получения пептидов или протеинов
US6956021B1 (en) * 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
PL197504B1 (pl) * 1998-10-16 2008-04-30 Novo Nordisk As Trwałe stężone preparaty insulinowe do podawania do płuc
US6211144B1 (en) 1998-10-16 2001-04-03 Novo Nordisk A/S Stable concentrated insulin preparations for pulmonary delivery
US6635617B1 (en) 1998-10-16 2003-10-21 Novo Nordisk A/S Insulin preparations for pulmonary delivery containing menthol
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US7196059B2 (en) * 2001-09-07 2007-03-27 Biocon Limited Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
US6770625B2 (en) 2001-09-07 2004-08-03 Nobex Corporation Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith
US7312192B2 (en) * 2001-09-07 2007-12-25 Biocon Limited Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
US7030082B2 (en) * 2001-09-07 2006-04-18 Nobex Corporation Pharmaceutical compositions of drug-oligomer conjugates and methods of treating disease therewith
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US7166571B2 (en) * 2001-09-07 2007-01-23 Biocon Limited Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
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CN106117345B (zh) * 2015-05-05 2020-11-24 宜昌东阳光长江药业股份有限公司 一种制备甘精胰岛素结晶的方法
CN104892749B (zh) * 2015-06-16 2019-02-05 珠海联邦制药股份有限公司 一种德谷胰岛素结晶的制备方法及应用
CN105753966A (zh) * 2016-05-05 2016-07-13 通化东宝药业股份有限公司 一种重组人胰岛素结晶的制备方法
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CN113896784B (zh) * 2021-10-18 2024-04-16 合肥天麦生物科技发展有限公司 一种胰岛素结晶的制备方法及其产品
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DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
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YU18596A (sh) * 1995-03-31 1998-07-10 Eli Lilly And Company Analogne formulacije monomernog insulina

Also Published As

Publication number Publication date
PL309099A1 (en) 1995-12-27
YU39595A (sh) 1997-08-22
ZA954942B (en) 1996-12-17
SI0692489T1 (en) 2003-06-30
ES2188637T3 (es) 2003-07-01
PL180968B1 (pl) 2001-05-31
HUT73495A (en) 1996-08-28
AU2168195A (en) 1996-01-04
RO113529B1 (ro) 1998-08-28
JPH08169899A (ja) 1996-07-02
KR100369951B1 (ko) 2003-03-28
ATE233278T1 (de) 2003-03-15
CA2151563C (en) 2007-08-07
EP0692489A1 (en) 1996-01-17
NZ272358A (en) 1996-12-20
AU697794B2 (en) 1998-10-15
CZ286066B6 (cs) 2000-01-12
IL114152A0 (en) 1995-10-31
HU9501715D0 (en) 1995-08-28
CO4410205A1 (es) 1997-01-09
DE69529708D1 (de) 2003-04-03
CA2151563A1 (en) 1995-12-17
RU2156257C2 (ru) 2000-09-20
MY130551A (en) 2007-06-29
CZ154195A3 (en) 1996-02-14
KR960000922A (ko) 1996-01-25
IL114152A (en) 1999-12-31
BR9502798A (pt) 1996-06-04
FI952930A0 (fi) 1995-06-14
EP0692489B1 (en) 2003-02-26
RU95110107A (ru) 1997-05-10
US5504188A (en) 1996-04-02
FI952930L (fi) 1995-12-17
NO952334D0 (no) 1995-06-13
IN178919B (enExample) 1997-07-19
TW379228B (en) 2000-01-11
DE69529708T2 (de) 2003-10-16
CN1184234C (zh) 2005-01-12
CN1128271A (zh) 1996-08-07
NO952334L (no) 1995-12-18
JP3595607B2 (ja) 2004-12-02
PE21896A1 (es) 1996-06-15
FI952930A7 (fi) 1995-12-17

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