DK0663906T3 - Fremgangsmåde til fremstilling af taxanderivater - Google Patents

Fremgangsmåde til fremstilling af taxanderivater

Info

Publication number
DK0663906T3
DK0663906T3 DK93921982.0T DK93921982T DK0663906T3 DK 0663906 T3 DK0663906 T3 DK 0663906T3 DK 93921982 T DK93921982 T DK 93921982T DK 0663906 T3 DK0663906 T3 DK 0663906T3
Authority
DK
Denmark
Prior art keywords
pct
vii
date
alkyl
alkenyl
Prior art date
Application number
DK93921982.0T
Other languages
Danish (da)
English (en)
Inventor
Jean-Manuel Mas
Viviane Charriere B Massonneau
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Application granted granted Critical
Publication of DK0663906T3 publication Critical patent/DK0663906T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
DK93921982.0T 1992-10-05 1993-10-04 Fremgangsmåde til fremstilling af taxanderivater DK0663906T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9211741A FR2696458B1 (fr) 1992-10-05 1992-10-05 Procédé de préparation de dérivés du taxane.

Publications (1)

Publication Number Publication Date
DK0663906T3 true DK0663906T3 (da) 1996-12-30

Family

ID=9434119

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93921982.0T DK0663906T3 (da) 1992-10-05 1993-10-04 Fremgangsmåde til fremstilling af taxanderivater

Country Status (24)

Country Link
US (3) US5616739A (de)
EP (1) EP0663906B1 (de)
JP (1) JP3014760B2 (de)
KR (1) KR100311198B1 (de)
AT (1) ATE146174T1 (de)
AU (1) AU689080B2 (de)
CA (1) CA2146250C (de)
CZ (1) CZ283261B6 (de)
DE (1) DE69306591T2 (de)
DK (1) DK0663906T3 (de)
ES (1) ES2095081T3 (de)
FI (1) FI109793B (de)
FR (1) FR2696458B1 (de)
GR (1) GR3021997T3 (de)
HU (1) HU226412B1 (de)
MX (1) MX9305766A (de)
NO (1) NO309089B1 (de)
NZ (1) NZ256445A (de)
PL (1) PL182284B1 (de)
RU (1) RU2116303C1 (de)
SK (1) SK280627B6 (de)
TW (1) TW419472B (de)
WO (1) WO1994007877A1 (de)
ZA (1) ZA937318B (de)

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FR2698361B1 (fr) * 1992-11-20 1995-01-13 Rhone Poulenc Rorer Sa Procédé de préparation d'un acide oxazolidine-1,3 carboxylique-5.
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US5973160A (en) * 1992-12-23 1999-10-26 Poss; Michael A. Methods for the preparation of novel sidechain-bearing taxanes
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FR2706457B1 (fr) * 1993-06-16 1995-07-28 Rhone Poulenc Rorer Sa Procédé de préparation d'un acide oxazolidinecarboxylique utile pour préparer des taxoïdes thérapeutiquement actifs.
US6005120A (en) 1993-07-20 1999-12-21 Florida State University Tricyclic and tetracyclic taxanes
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Family Cites Families (5)

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US5175315A (en) * 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
US5136060A (en) * 1989-11-14 1992-08-04 Florida State University Method for preparation of taxol using an oxazinone
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MX9102128A (es) * 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
US5319112A (en) * 1992-08-18 1994-06-07 Virgnia Tech Intellectual Properties, Inc. Method for the conversion of cephalomannine to taxol and for the preparation of N-acyl analogs of taxol

Also Published As

Publication number Publication date
SK280627B6 (sk) 2000-05-16
TW419472B (en) 2001-01-21
AU689080B2 (en) 1998-03-26
CZ84195A3 (en) 1995-09-13
SK43695A3 (en) 1995-08-09
FI951595A0 (fi) 1995-04-04
US5869680A (en) 1999-02-09
JP3014760B2 (ja) 2000-02-28
FR2696458A1 (fr) 1994-04-08
EP0663906B1 (de) 1996-12-11
DE69306591D1 (de) 1997-01-23
CA2146250A1 (fr) 1994-04-14
ATE146174T1 (de) 1996-12-15
HUT72679A (en) 1996-05-28
HU9500971D0 (en) 1995-06-28
ZA937318B (en) 1994-04-25
US5677462A (en) 1997-10-14
KR100311198B1 (ko) 2002-04-24
MX9305766A (es) 1995-01-31
NZ256445A (en) 1997-01-29
FR2696458B1 (fr) 1994-11-10
DE69306591T2 (de) 1997-04-17
AU5115093A (en) 1994-04-26
EP0663906A1 (de) 1995-07-26
GR3021997T3 (en) 1997-03-31
NO309089B1 (no) 2000-12-11
RU2116303C1 (ru) 1998-07-27
NO951201L (no) 1995-03-29
RU95113717A (ru) 1996-12-27
FI951595A (fi) 1995-04-04
US5616739A (en) 1997-04-01
CZ283261B6 (cs) 1998-02-18
CA2146250C (fr) 2003-03-11
HU226412B1 (en) 2008-11-28
KR950703546A (ko) 1995-09-20
ES2095081T3 (es) 1997-02-01
PL182284B1 (pl) 2001-12-31
JPH08501788A (ja) 1996-02-27
PL308241A1 (en) 1995-07-24
FI109793B (fi) 2002-10-15
WO1994007877A1 (fr) 1994-04-14
NO951201D0 (no) 1995-03-29

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