GR3021997T3 - Method of preparing taxane derivatives. - Google Patents

Method of preparing taxane derivatives.

Info

Publication number
GR3021997T3
GR3021997T3 GR960402201T GR960402201T GR3021997T3 GR 3021997 T3 GR3021997 T3 GR 3021997T3 GR 960402201 T GR960402201 T GR 960402201T GR 960402201 T GR960402201 T GR 960402201T GR 3021997 T3 GR3021997 T3 GR 3021997T3
Authority
GR
Greece
Prior art keywords
pct
vii
date
alkyl
alkenyl
Prior art date
Application number
GR960402201T
Other languages
English (en)
Inventor
Jean-Manuel Mas
Viviane Charriere B Massonneau
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of GR3021997T3 publication Critical patent/GR3021997T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
GR960402201T 1992-10-05 1996-12-12 Method of preparing taxane derivatives. GR3021997T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9211741A FR2696458B1 (fr) 1992-10-05 1992-10-05 Procédé de préparation de dérivés du taxane.
PCT/FR1993/000967 WO1994007877A1 (fr) 1992-10-05 1993-10-04 Procede de preparation de derives du taxane

Publications (1)

Publication Number Publication Date
GR3021997T3 true GR3021997T3 (en) 1997-03-31

Family

ID=9434119

Family Applications (1)

Application Number Title Priority Date Filing Date
GR960402201T GR3021997T3 (en) 1992-10-05 1996-12-12 Method of preparing taxane derivatives.

Country Status (24)

Country Link
US (3) US5616739A (el)
EP (1) EP0663906B1 (el)
JP (1) JP3014760B2 (el)
KR (1) KR100311198B1 (el)
AT (1) ATE146174T1 (el)
AU (1) AU689080B2 (el)
CA (1) CA2146250C (el)
CZ (1) CZ283261B6 (el)
DE (1) DE69306591T2 (el)
DK (1) DK0663906T3 (el)
ES (1) ES2095081T3 (el)
FI (1) FI109793B (el)
FR (1) FR2696458B1 (el)
GR (1) GR3021997T3 (el)
HU (1) HU226412B1 (el)
MX (1) MX9305766A (el)
NO (1) NO309089B1 (el)
NZ (1) NZ256445A (el)
PL (1) PL182284B1 (el)
RU (1) RU2116303C1 (el)
SK (1) SK280627B6 (el)
TW (1) TW419472B (el)
WO (1) WO1994007877A1 (el)
ZA (1) ZA937318B (el)

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FR2696464B1 (fr) * 1992-10-05 1994-11-10 Rhone Poulenc Rorer Sa Nouveau procédé d'estérification de la baccatine III et de la désacétyl-10 baccatine III.
FR2697522B1 (fr) * 1992-10-30 1994-11-25 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.
FR2698361B1 (fr) * 1992-11-20 1995-01-13 Rhone Poulenc Rorer Sa Procédé de préparation d'un acide oxazolidine-1,3 carboxylique-5.
IL107950A (en) 1992-12-15 2001-04-30 Upjohn Co b 7, b 8 - Matano - Taxols, their preparation and pharmaceutical preparations against malignant tumors containing them
US5973160A (en) * 1992-12-23 1999-10-26 Poss; Michael A. Methods for the preparation of novel sidechain-bearing taxanes
DE69433146T2 (de) * 1993-06-11 2004-06-09 Pharmacia & Upjohn Co., Kalamazoo Delta 6,7-Taxol Derivate antineoplastische Verbindungen und diese enthaltende pharmazeutische Zusammenstellungen
FR2706457B1 (fr) * 1993-06-16 1995-07-28 Rhone Poulenc Rorer Sa Procédé de préparation d'un acide oxazolidinecarboxylique utile pour préparer des taxoïdes thérapeutiquement actifs.
US6005120A (en) 1993-07-20 1999-12-21 Florida State University Tricyclic and tetracyclic taxanes
EP0728130A1 (en) * 1993-11-12 1996-08-28 PHARMACIA & UPJOHN COMPANY Pyrimidine-thioalkyl and alkylether compounds
IL112412A (en) * 1994-01-28 2000-02-29 Upjohn Co Delta 12,13-iso-taxol analogs and antineoplastic pharmaceutical compositions containing them
US5679807A (en) * 1995-01-30 1997-10-21 Hauser, Inc. Preparation of taxol and docetaxel through primary amines
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Family Cites Families (5)

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US5175315A (en) * 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
US5136060A (en) * 1989-11-14 1992-08-04 Florida State University Method for preparation of taxol using an oxazinone
US5015744A (en) * 1989-11-14 1991-05-14 Florida State University Method for preparation of taxol using an oxazinone
MX9102128A (es) * 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
US5319112A (en) * 1992-08-18 1994-06-07 Virgnia Tech Intellectual Properties, Inc. Method for the conversion of cephalomannine to taxol and for the preparation of N-acyl analogs of taxol

Also Published As

Publication number Publication date
DE69306591T2 (de) 1997-04-17
SK280627B6 (sk) 2000-05-16
PL308241A1 (en) 1995-07-24
CA2146250C (fr) 2003-03-11
DE69306591D1 (de) 1997-01-23
US5616739A (en) 1997-04-01
AU5115093A (en) 1994-04-26
FI951595A0 (fi) 1995-04-04
MX9305766A (es) 1995-01-31
RU95113717A (ru) 1996-12-27
NZ256445A (en) 1997-01-29
EP0663906B1 (fr) 1996-12-11
KR950703546A (ko) 1995-09-20
CZ283261B6 (cs) 1998-02-18
EP0663906A1 (fr) 1995-07-26
JPH08501788A (ja) 1996-02-27
ATE146174T1 (de) 1996-12-15
PL182284B1 (pl) 2001-12-31
US5677462A (en) 1997-10-14
SK43695A3 (en) 1995-08-09
JP3014760B2 (ja) 2000-02-28
FR2696458B1 (fr) 1994-11-10
CZ84195A3 (en) 1995-09-13
NO951201D0 (no) 1995-03-29
US5869680A (en) 1999-02-09
FI109793B (fi) 2002-10-15
NO951201L (no) 1995-03-29
HU9500971D0 (en) 1995-06-28
ES2095081T3 (es) 1997-02-01
HUT72679A (en) 1996-05-28
AU689080B2 (en) 1998-03-26
KR100311198B1 (ko) 2002-04-24
FI951595A (fi) 1995-04-04
CA2146250A1 (fr) 1994-04-14
HU226412B1 (en) 2008-11-28
TW419472B (en) 2001-01-21
RU2116303C1 (ru) 1998-07-27
ZA937318B (en) 1994-04-25
NO309089B1 (no) 2000-12-11
DK0663906T3 (da) 1996-12-30
FR2696458A1 (fr) 1994-04-08
WO1994007877A1 (fr) 1994-04-14

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