FI951595A - Menetelmä taksaanijohdannaisten valmistamiseksi - Google Patents

Menetelmä taksaanijohdannaisten valmistamiseksi Download PDF

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Publication number
FI951595A
FI951595A FI951595A FI951595A FI951595A FI 951595 A FI951595 A FI 951595A FI 951595 A FI951595 A FI 951595A FI 951595 A FI951595 A FI 951595A FI 951595 A FI951595 A FI 951595A
Authority
FI
Finland
Prior art keywords
pct
vii
date
alkyl
alkenyl
Prior art date
Application number
FI951595A
Other languages
English (en)
Swedish (sv)
Other versions
FI951595A0 (fi
FI109793B (fi
Inventor
Jean-Manuel Mas
Viviane Massonneau
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of FI951595A publication Critical patent/FI951595A/fi
Publication of FI951595A0 publication Critical patent/FI951595A0/fi
Application granted granted Critical
Publication of FI109793B publication Critical patent/FI109793B/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI951595A 1992-10-05 1995-04-04 Menetelmä taksaanijohdannaisten valmistamiseksi, menetelmässä käytettävä lähtöaine ja välituote FI109793B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR9211741A FR2696458B1 (fr) 1992-10-05 1992-10-05 Procédé de préparation de dérivés du taxane.
FR9211741 1992-10-05
PCT/FR1993/000967 WO1994007877A1 (fr) 1992-10-05 1993-10-04 Procede de preparation de derives du taxane
FR9300967 1993-10-04

Publications (3)

Publication Number Publication Date
FI951595A true FI951595A (fi) 1995-04-04
FI951595A0 FI951595A0 (fi) 1995-04-04
FI109793B FI109793B (fi) 2002-10-15

Family

ID=9434119

Family Applications (1)

Application Number Title Priority Date Filing Date
FI951595A FI109793B (fi) 1992-10-05 1995-04-04 Menetelmä taksaanijohdannaisten valmistamiseksi, menetelmässä käytettävä lähtöaine ja välituote

Country Status (24)

Country Link
US (3) US5616739A (fi)
EP (1) EP0663906B1 (fi)
JP (1) JP3014760B2 (fi)
KR (1) KR100311198B1 (fi)
AT (1) ATE146174T1 (fi)
AU (1) AU689080B2 (fi)
CA (1) CA2146250C (fi)
CZ (1) CZ283261B6 (fi)
DE (1) DE69306591T2 (fi)
DK (1) DK0663906T3 (fi)
ES (1) ES2095081T3 (fi)
FI (1) FI109793B (fi)
FR (1) FR2696458B1 (fi)
GR (1) GR3021997T3 (fi)
HU (1) HU226412B1 (fi)
MX (1) MX9305766A (fi)
NO (1) NO309089B1 (fi)
NZ (1) NZ256445A (fi)
PL (1) PL182284B1 (fi)
RU (1) RU2116303C1 (fi)
SK (1) SK280627B6 (fi)
TW (1) TW419472B (fi)
WO (1) WO1994007877A1 (fi)
ZA (1) ZA937318B (fi)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
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FR2696464B1 (fr) * 1992-10-05 1994-11-10 Rhone Poulenc Rorer Sa Nouveau procédé d'estérification de la baccatine III et de la désacétyl-10 baccatine III.
FR2697522B1 (fr) * 1992-10-30 1994-11-25 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.
FR2698361B1 (fr) * 1992-11-20 1995-01-13 Rhone Poulenc Rorer Sa Procédé de préparation d'un acide oxazolidine-1,3 carboxylique-5.
MX9307777A (es) 1992-12-15 1994-07-29 Upjohn Co 7-HALO-Y 7ß, 8ß-METANO-TAXOLES, USO ANTINEOPLASTICO Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN.
US5973160A (en) * 1992-12-23 1999-10-26 Poss; Michael A. Methods for the preparation of novel sidechain-bearing taxanes
ATE249448T1 (de) * 1993-06-11 2003-09-15 Upjohn Co Delta 6,7-taxol derivate antineoplastische verbindungen und diese enthaltende pharmazeutische zusammenstellungen
FR2706457B1 (fr) * 1993-06-16 1995-07-28 Rhone Poulenc Rorer Sa Procédé de préparation d'un acide oxazolidinecarboxylique utile pour préparer des taxoïdes thérapeutiquement actifs.
US6005120A (en) 1993-07-20 1999-12-21 Florida State University Tricyclic and tetracyclic taxanes
US5981537A (en) * 1993-11-12 1999-11-09 Pharmacia & Upjohn Company Pyrimidine-thioalkyl and alkylether compounds
IL127597A (en) * 1994-01-28 2003-07-31 Upjohn Co Iso-taxol analogs
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US7407973B2 (en) * 2003-10-24 2008-08-05 Intermune, Inc. Use of pirfenidone in therapeutic regimens
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Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5175315A (en) * 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
US5136060A (en) * 1989-11-14 1992-08-04 Florida State University Method for preparation of taxol using an oxazinone
US5015744A (en) * 1989-11-14 1991-05-14 Florida State University Method for preparation of taxol using an oxazinone
MX9102128A (es) * 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
US5319112A (en) * 1992-08-18 1994-06-07 Virgnia Tech Intellectual Properties, Inc. Method for the conversion of cephalomannine to taxol and for the preparation of N-acyl analogs of taxol

Also Published As

Publication number Publication date
AU5115093A (en) 1994-04-26
FR2696458B1 (fr) 1994-11-10
KR100311198B1 (ko) 2002-04-24
JPH08501788A (ja) 1996-02-27
FI951595A0 (fi) 1995-04-04
TW419472B (en) 2001-01-21
FI109793B (fi) 2002-10-15
SK43695A3 (en) 1995-08-09
AU689080B2 (en) 1998-03-26
DE69306591T2 (de) 1997-04-17
CZ84195A3 (en) 1995-09-13
NO951201L (no) 1995-03-29
GR3021997T3 (en) 1997-03-31
HU226412B1 (en) 2008-11-28
US5616739A (en) 1997-04-01
CA2146250C (fr) 2003-03-11
ATE146174T1 (de) 1996-12-15
EP0663906B1 (fr) 1996-12-11
HU9500971D0 (en) 1995-06-28
FR2696458A1 (fr) 1994-04-08
SK280627B6 (sk) 2000-05-16
JP3014760B2 (ja) 2000-02-28
HUT72679A (en) 1996-05-28
NO951201D0 (no) 1995-03-29
WO1994007877A1 (fr) 1994-04-14
EP0663906A1 (fr) 1995-07-26
NZ256445A (en) 1997-01-29
ZA937318B (en) 1994-04-25
NO309089B1 (no) 2000-12-11
DK0663906T3 (da) 1996-12-30
CA2146250A1 (fr) 1994-04-14
PL308241A1 (en) 1995-07-24
KR950703546A (ko) 1995-09-20
ES2095081T3 (es) 1997-02-01
MX9305766A (es) 1995-01-31
US5677462A (en) 1997-10-14
RU2116303C1 (ru) 1998-07-27
US5869680A (en) 1999-02-09
CZ283261B6 (cs) 1998-02-18
PL182284B1 (pl) 2001-12-31
RU95113717A (ru) 1996-12-27
DE69306591D1 (de) 1997-01-23

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