DK0561639T3 - Cyklisk peptid-antisvampemidler og fremgangsmåde til fremstilling deraf - Google Patents

Cyklisk peptid-antisvampemidler og fremgangsmåde til fremstilling deraf

Info

Publication number
DK0561639T3
DK0561639T3 DK93302064T DK93302064T DK0561639T3 DK 0561639 T3 DK0561639 T3 DK 0561639T3 DK 93302064 T DK93302064 T DK 93302064T DK 93302064 T DK93302064 T DK 93302064T DK 0561639 T3 DK0561639 T3 DK 0561639T3
Authority
DK
Denmark
Prior art keywords
hydrogen
preparation
antifungal agents
cyclic peptide
hydroxy
Prior art date
Application number
DK93302064T
Other languages
Danish (da)
English (en)
Inventor
Manuel Debono
Frederick Joseph Burkhardt
Jeffrey Scott Nissen
Jr William Wilson Turner
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK0561639T3 publication Critical patent/DK0561639T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/66—Gramicidins S, C; Tyrocidins A, B, C; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
DK93302064T 1992-03-19 1993-03-18 Cyklisk peptid-antisvampemidler og fremgangsmåde til fremstilling deraf DK0561639T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85411792A 1992-03-19 1992-03-19
US99239092A 1992-12-16 1992-12-16

Publications (1)

Publication Number Publication Date
DK0561639T3 true DK0561639T3 (da) 2002-06-17

Family

ID=27127211

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93302064T DK0561639T3 (da) 1992-03-19 1993-03-18 Cyklisk peptid-antisvampemidler og fremgangsmåde til fremstilling deraf

Country Status (25)

Country Link
EP (1) EP0561639B1 (OSRAM)
JP (3) JP3519754B2 (OSRAM)
KR (1) KR100256036B1 (OSRAM)
CN (1) CN1036715C (OSRAM)
AT (1) ATE217635T1 (OSRAM)
AU (2) AU3534193A (OSRAM)
BR (1) BR9301232A (OSRAM)
CA (1) CA2091663C (OSRAM)
CZ (1) CZ288974B6 (OSRAM)
DE (2) DE122008000006I2 (OSRAM)
DK (1) DK0561639T3 (OSRAM)
ES (1) ES2174843T3 (OSRAM)
FI (1) FI118768B (OSRAM)
HU (2) HU225783B1 (OSRAM)
IL (3) IL105048A (OSRAM)
LU (1) LU91406I2 (OSRAM)
MX (1) MX9301457A (OSRAM)
MY (1) MY136593A (OSRAM)
NL (1) NL300334I2 (OSRAM)
NO (1) NO930948L (OSRAM)
NZ (3) NZ512085A (OSRAM)
PT (1) PT561639E (OSRAM)
RU (1) RU2129562C1 (OSRAM)
TW (1) TW264477B (OSRAM)
YU (1) YU49108B (OSRAM)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5430018A (en) * 1991-10-17 1995-07-04 Merck & Co., Inc. Cyclohexapeptide with basic nitrogen containing alkylamide groups
TW264477B (OSRAM) * 1992-03-19 1995-12-01 Lilly Co Eli
US6743777B1 (en) 1992-03-19 2004-06-01 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
US5378804A (en) * 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
AU674233B2 (en) * 1993-05-04 1996-12-12 Merck & Co., Inc. Cyclohexapeptidyl aminoalkyl ethers
US5948753A (en) * 1993-05-04 1999-09-07 Merck & Co., Inc. Cyclohexapeptidyl propanolamine compounds
AU7874494A (en) * 1993-09-22 1995-04-10 Merck & Co., Inc. Antifungal and anti-pneumocystis compounds, compositions containing such compounds, and methods of use
JP3657989B2 (ja) * 1994-09-16 2005-06-08 メルク エンド カンパニー インコーポレーテッド アザシクロヘキサペプチド化合物
US5516757A (en) * 1994-09-16 1996-05-14 Merck & Co., Inc. Semi-synthetic lipopeptides, compositions containing said lipopeptides, and methods of use
US5514651A (en) * 1994-09-16 1996-05-07 Merck & Co., Inc. Aza cyclohexapeptide compounds
DE69529172T2 (de) * 1994-10-07 2003-04-17 Fujisawa Pharmaceutical Co., Ltd. Zyklische hexapeptide mit antibiotischer aktivität
US5516756A (en) * 1994-10-31 1996-05-14 Merck & Co., Inc. Aza cyclohexapeptide compounds
PT805685E (pt) * 1995-01-26 2002-02-28 Merck & Co Inc Novos ciclo-hexapeptideos anti-fungicos
US5646111A (en) * 1995-04-07 1997-07-08 Eli Lilly And Company Cyclic peptide antifungal Agents
US5786325A (en) * 1995-05-26 1998-07-28 Eli Lilly And Company Cyclic peptide antifungal agents and methods of making and using
US5652213A (en) * 1995-05-26 1997-07-29 Eli Lilly And Company Cyclic peptide antifungal agents
US5618787A (en) * 1995-05-26 1997-04-08 Eli Lilly And Company Cyclic peptide antifungal agents
US5629290A (en) * 1995-05-26 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
US5629289A (en) * 1995-07-25 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
US5693611A (en) * 1996-02-01 1997-12-02 Eli Lilly And Company Cyclic peptide antifungal agents
WO1997027864A1 (en) * 1996-02-01 1997-08-07 Eli Lilly And Company Cyclic peptide antifungal agents
JPH09227422A (ja) * 1996-02-12 1997-09-02 Rolic Ag シクロペンチル誘導体
US5696084A (en) * 1996-08-16 1997-12-09 Abbott Laboratories Amino-lipopetide antifungal agents
AUPO381496A0 (en) * 1996-11-25 1996-12-19 Fujisawa Pharmaceutical Co., Ltd. New compound
FR2784993B1 (fr) * 1998-10-26 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'echinocandine, leur procede de preparation et leur application comme fongicides
AU2003200556B2 (en) * 1997-12-10 2005-12-01 Novexel Echinocandin derivative and their preparation method
UA72200C2 (uk) * 1997-12-10 2005-02-15 Авентіс Фарма С.А. Похідні ехінокандину, спосіб їх одержання, їх застосування, проміжні сполуки та фармацевтична композиція
AUPP172898A0 (en) * 1998-02-09 1998-03-05 Fujisawa Pharmaceutical Co., Ltd. New compound
US6730776B1 (en) * 1998-03-16 2004-05-04 Fujisawa Pharmaceutical Co., Ltd. WF14573 or its salt, production thereof and use thereof
DE69923460T2 (de) 1998-08-20 2007-01-11 Eli Lilly And Co., Indianapolis Verfahren zur herstellung von ring-modifizierten zyklischen peptidanalogen
EP1137663B1 (en) 1998-12-09 2006-08-30 Eli Lilly And Company Purification of echinocandin cyclopeptide compounds
DE19907904A1 (de) 1999-02-24 2000-08-31 Clariant Gmbh Verfahren zur Herstellung von [1,1':4',1"]-Terphenylverbindungen
EP1156784A1 (en) 1999-03-03 2001-11-28 Eli Lilly And Company Processes for making pharmaceutical oral ecb formulations and compositions
BR0009248A (pt) 1999-03-03 2001-11-20 Lilly Co Eli Formação e troca de ânion de sais de amÈnioequinocandina cristalinos
BR0008712A (pt) 1999-03-03 2001-12-26 Lilly Co Eli Complexos equinocandina/carboidrato
EP1156782B1 (en) 1999-03-03 2005-05-04 Eli Lilly And Company Echinocandin pharmaceutical formulations containing micelle-forming surfactants
ATE302184T1 (de) * 2000-02-18 2005-09-15 Meiji Seika Kaisha Phenoxyalkylaminderivate als agonisten des opioid-delta rezeptors
FR2833596B1 (fr) * 2001-12-14 2005-02-18 Aventis Pharma Sa Procede de preparation de derives d'echinocandine
US6991800B2 (en) 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
US7524878B2 (en) * 2003-04-30 2009-04-28 The Institute For Pharmaceuticals Discovery Llc Phenyl substituted carboxylic acids
KR101551207B1 (ko) * 2008-09-04 2015-09-08 롬엔드하스전자재료코리아유한회사 신규한 유기 발광 화합물 및 이를 발광재료로서 채용하고 있는 유기 발광 소자
CN102464704B (zh) * 2010-11-05 2013-12-11 上海医药工业研究院 一种化合物及其制备方法和用途
WO2013142279A1 (en) * 2012-03-19 2013-09-26 Seachaid Pharmaceuticals, Inc. Dosing regimens for echinocandin class compounds
EP3058958B1 (en) 2015-02-23 2018-09-19 Selectchemie AG Anidulafungin composition
JP6866583B2 (ja) * 2016-07-05 2021-04-28 Dic株式会社 液晶化合物
CN116903706B (zh) * 2023-06-13 2024-05-17 深圳市祥根生物有限公司 一种棘白菌素类药物及其制备方法和用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE886576A (fr) * 1979-12-13 1981-06-10 Lilly Co Eli Derives de noyaux peptidiques cycliques, leur preparation et leur utilisation comme agents antifongiques
BE886575A (fr) * 1979-12-13 1981-06-10 Lilly Co Eli Derives de noyaux peptidiques cycliques, leur preparation et leur utilisation comme agents antifongiques
CA2037957A1 (en) * 1990-03-12 1991-09-13 Merck & Co., Inc. N-acylated cyclohexapeptide compounds
GB2241956A (en) 1990-03-16 1991-09-18 Merck & Co Inc N-acylated cyclohexapeptide compounds
IL97347A0 (en) * 1990-03-19 1992-05-25 Merck & Co Inc Lipopeptide derivatives and antimicrobial compositions containing them
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
US5310726A (en) * 1990-03-19 1994-05-10 Merck & Co., Inc. Lipopeptide compounds
TW264477B (OSRAM) * 1992-03-19 1995-12-01 Lilly Co Eli

Also Published As

Publication number Publication date
EP0561639A1 (en) 1993-09-22
YU49108B (sh) 2004-03-12
MY136593A (en) 2008-10-31
CA2091663A1 (en) 1993-09-20
NZ247149A (en) 1996-10-28
IL105048A (en) 2001-06-14
JP2002226500A (ja) 2002-08-14
AU3534193A (en) 1993-09-23
NL300334I1 (nl) 2008-03-03
KR100256036B1 (ko) 2000-05-01
NO930948D0 (no) 1993-03-16
JP3520071B2 (ja) 2004-04-19
RU2129562C1 (ru) 1999-04-27
DE122008000006I1 (de) 2008-04-17
TW264477B (OSRAM) 1995-12-01
EP0561639B1 (en) 2002-05-15
KR930019694A (ko) 1993-10-18
AU689391B2 (en) 1998-03-26
ES2174843T3 (es) 2002-11-16
HU211562A9 (en) 1995-12-28
NO930948L (no) 1993-09-20
DE69331922D1 (de) 2002-06-20
HUT63637A (en) 1993-09-28
FI931202L (fi) 1993-09-20
IL105048A0 (en) 1993-07-08
CZ288974B6 (cs) 2001-10-17
NZ299314A (en) 2001-09-28
YU18593A (sh) 1996-10-09
IL122315A0 (en) 1998-04-05
DE69331922T2 (de) 2002-08-29
CA2091663C (en) 2007-10-30
CN1080926A (zh) 1994-01-19
FI931202A0 (fi) 1993-03-18
CZ41693A3 (en) 1994-07-13
ATE217635T1 (de) 2002-06-15
BR9301232A (pt) 1993-09-21
PT561639E (pt) 2002-10-31
MX9301457A (es) 1994-02-28
FI118768B (fi) 2008-03-14
JPH0656892A (ja) 1994-03-01
HU9300785D0 (en) 1993-06-28
IL122315A (en) 2002-03-10
HU225783B1 (en) 2007-09-28
DE122008000006I2 (de) 2011-07-21
JP3519754B2 (ja) 2004-04-19
AU6552996A (en) 1996-12-05
NL300334I2 (nl) 2008-05-01
NZ512085A (en) 2003-08-29
CN1036715C (zh) 1997-12-17
LU91406I2 (fr) 2008-03-10
JP2004115540A (ja) 2004-04-15

Similar Documents

Publication Publication Date Title
DK0561639T3 (da) Cyklisk peptid-antisvampemidler og fremgangsmåde til fremstilling deraf
DK0772397T3 (da) Midler, der indeholder insekticid og fungicid, til bekæmpelse af planteskadelige organismer
ATE196913T1 (de) Neuartige peptidderivate
FI942499A0 (fi) Indolijohdannainen, menetelmä sen valmistamiseksi ja sen lääkekäyttö
ZA927606B (en) Antifungal agent.
MY116862A (en) New processes for preparing pesticidal intermediates
FI94354C (fi) Menetelmä farmaseuttisesti aktiivisten peptidien valmistamiseksi
ES2046641T3 (es) Composicion antitumoral.
DK0478194T3 (da) Bis-(2-aminocarbonylcykloalk-1-enyl)-disulfider, fremstilling og anvendelse heraf
FI95247C (fi) Menetelmä lääkeaineina käytettävien 1,3-tiatsolidinien -karbonyylikarboksiamidien valmistamiseksi
EP0245902A3 (en) Benzothiazinone derivatives
NO173991C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive 1,2,5-ditiazocin-derivater
EP0555479A4 (OSRAM)
GR3007219T3 (OSRAM)
NO953557D0 (no) Antitumorpreparater og fremgangsmåte for deres fremstilling
DK269785A (da) 4(5-)substituerede imidazoler og fremgangsmaade til fremstilling heraf
TW275629B (OSRAM)
HU907489D0 (en) Process for the production of sulphonylkarbamide derivatives and herbicide preparations containing them as active agents
LU88449I2 (fr) Fleroxacine et ses dérivés pharmaceutiquement acceptables.
DE3782229D1 (de) Verwendung von 2-oxo-imidazolidin-derivaten zur behandlung von nierenkrankheiten.
GR76446B (OSRAM)