DK0474126T3 - - Google Patents

Info

Publication number
DK0474126T3
DK0474126T3 DK91114598.5T DK91114598T DK0474126T3 DK 0474126 T3 DK0474126 T3 DK 0474126T3 DK 91114598 T DK91114598 T DK 91114598T DK 0474126 T3 DK0474126 T3 DK 0474126T3
Authority
DK
Denmark
Prior art keywords
ointment
octacos
tetraone
azatricyclo
methoxycyclohexyl
Prior art date
Application number
DK91114598.5T
Other languages
Danish (da)
English (en)
Inventor
Sotoo Asakura
Yoshio Murakami
Nobuto Kanagawa
Toshiomi Nakate
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=16982211&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0474126(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Application granted granted Critical
Publication of DK0474126T3 publication Critical patent/DK0474126T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK91114598.5T 1990-09-04 1991-08-30 DK0474126T3 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP23517790 1990-09-04

Publications (1)

Publication Number Publication Date
DK0474126T3 true DK0474126T3 (zh) 1997-04-07

Family

ID=16982211

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91114598.5T DK0474126T3 (zh) 1990-09-04 1991-08-30

Country Status (20)

Country Link
US (1) US5385907A (zh)
EP (1) EP0474126B1 (zh)
JP (1) JP2526752B2 (zh)
KR (1) KR100194240B1 (zh)
CN (1) CN1069193C (zh)
AT (1) ATE150304T1 (zh)
AU (1) AU656145B2 (zh)
CA (1) CA2050623C (zh)
DE (1) DE69125230T2 (zh)
DK (1) DK0474126T3 (zh)
ES (1) ES2099112T3 (zh)
GR (1) GR3022883T3 (zh)
HK (1) HK1000006A1 (zh)
HU (2) HUT59002A (zh)
IE (1) IE913085A1 (zh)
PH (1) PH31282A (zh)
PT (1) PT98862B (zh)
RU (1) RU2079303C1 (zh)
SG (1) SG46547A1 (zh)
ZA (1) ZA916983B (zh)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0669127B1 (en) * 1992-11-18 1999-08-11 Fujisawa Pharmaceutical Co., Ltd. Prolonged-action pharmaceutical preparation
JPH06345646A (ja) * 1993-06-08 1994-12-20 Fujisawa Pharmaceut Co Ltd ローション剤
DE19549794B4 (de) * 1994-10-26 2009-07-30 Novartis Ag Pharmazeutische Zusammensetzungen
AU735106B2 (en) * 1994-10-26 2001-06-28 Novartis Ag Pharmaceutical compositions
CN100335063C (zh) * 1994-10-26 2007-09-05 诺瓦蒂斯有限公司 药物组合物
GB2327611B (en) * 1994-10-26 1999-06-02 Novartis Ag Macrolide compositions
GB2327610B (en) * 1994-11-04 1999-06-02 Novartis Ag Macrolide compositions
AR004480A1 (es) * 1995-04-06 1998-12-16 Amico Derin C D Compuestos de ascomicina que poseen actividad antiinflamatoria, pro cedimiento para prepararlos, uso de dichos compuestos para preparar agentesfarmaceuticos y composiciones farmaceuticas que los incluyen
US5993787A (en) * 1996-09-13 1999-11-30 Johnson & Johnson Consumer Products, Inc. Composition base for topical therapeutic and cosmetic preparations
AU5340298A (en) * 1996-12-27 1998-07-31 Takeda Chemical Industries Ltd. Stabilized tricyclic compound
TW450810B (en) * 1997-02-20 2001-08-21 Fujisawa Pharmaceutical Co Macrolides antibiotic pharmaceutical composition for preventing and treating skin diseases
GB9723669D0 (en) * 1997-11-07 1998-01-07 Univ Aberdeen Skin penetration enhancing components
CN1161117C (zh) * 1998-04-27 2004-08-11 藤泽药品工业株式会社 药物组合物
GB9817064D0 (en) * 1998-08-05 1998-10-07 Fujisawa Pharmaceutical Co New use
US6300341B1 (en) 1998-09-30 2001-10-09 The Procter & Gamble Co. 2-substituted heterocyclic sulfonamides
US6307049B1 (en) 1998-09-30 2001-10-23 The Procter & Gamble Co. Heterocyclic 2-substituted ketoamides
GB9826656D0 (en) * 1998-12-03 1999-01-27 Novartis Ag Organic compounds
AUPR529701A0 (en) * 2001-05-28 2001-06-21 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical composition
NZ530845A (en) * 2001-07-06 2006-03-31 Sucampo Ag Composition for topical administration
PE20030828A1 (es) * 2002-03-04 2003-11-04 Novartis Ag Composicion oftalmica que comprende ascomicina
CA2492989C (en) * 2002-07-23 2012-11-20 Novartis Ag Ophthalmic ointment composition comprising a drug, an ointment base and a solubilizing/dispersing agent
GB0218996D0 (en) * 2002-08-14 2002-09-25 Novartis Ag Organic compounds
ZA200804907B (en) * 2004-08-18 2009-04-29 Ace Aps Cosmetic and pharmaceutical compositions comprising ACE inhibitors and/or angiotensin II receptor antagonists
AU2005232248B2 (en) * 2005-01-04 2011-08-04 Texas United Chemical Company, Llc Compounded hydrocarbon oil and oil base drilling fluids prepared therefrom
CN101119730A (zh) * 2005-02-14 2008-02-06 大正制药株式会社 软膏剂
WO2006098353A1 (ja) * 2005-03-15 2006-09-21 Kyowa Hakko Kogyo Co., Ltd. 外用剤
PL1992622T3 (pl) 2006-02-21 2012-01-31 Eisai R&D Man Co Ltd Pochodna 4-(3-benzoiloaminofenylo)-6,7-dimetoksy-2-metyloaminochinazoliny
EP2123641A4 (en) 2007-02-16 2011-06-22 Eisai R&D Man Co Ltd CRYSTAL, AMORPHOUS FORM AND METHYL N-Ý3- (6,7-DIMETHOXY-2-METHYLAMINOQUINAZOLINE-4-YL) PHENYLENE TEREPHTALIC ACID SALT
US10265265B2 (en) 2007-03-15 2019-04-23 Drug Delivery Solutions Limited Topical composition
CN102532041A (zh) 2007-08-17 2012-07-04 卫材R&D管理有限公司 喹唑啉衍生物的制造方法
TWI414296B (zh) 2007-08-17 2013-11-11 Eisai R&D Man Co Ltd Innovative agents
ES2478845T3 (es) 2008-10-08 2014-07-23 Takata Seiyaku Co., Ltd. Preparación de tacrolimus para aplicaciones externas
JP2010132607A (ja) * 2008-12-05 2010-06-17 Taisho Pharm Ind Ltd アトピー性皮膚炎治療用軟膏剤
JP2010202546A (ja) * 2009-03-02 2010-09-16 Taisho Pharm Ind Ltd アトピー性皮膚炎の治療用軟膏製剤
AU2012211809A1 (en) * 2011-01-31 2013-09-05 Osaka University Externally-used drug for treating skin disorder and method for producing same
CN102885761B (zh) * 2012-09-24 2015-08-05 浙江万晟药业有限公司 一种制备他克莫司软膏的方法
RU2538680C2 (ru) * 2013-03-12 2015-01-10 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Фармацевтическая композиция для лечения атопического дерматита и способ ее получения
RU2553600C2 (ru) * 2013-05-16 2015-06-20 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Фармацевтическая композиция для лечения заболеваний кожи
CN104127369A (zh) * 2014-07-02 2014-11-05 人福医药集团股份公司 他克莫司软膏及其制备方法
EP3977995A1 (en) 2014-10-28 2022-04-06 Koushi Yamaguchi Tacrolimus for ameliorating pregnancy conditions
CN106309353A (zh) * 2015-06-19 2017-01-11 江苏吉贝尔药业股份有限公司 一种治疗银屑病的软膏剂及其制备方法
CN109069418A (zh) 2016-04-04 2018-12-21 药品配送方案有限公司 包含他克莫司的局部组合物
CN105769752B (zh) * 2016-04-08 2018-12-11 湖北人福成田药业有限公司 制备他克莫司软膏的方法及他克莫司软膏
EP3542788A1 (en) 2018-03-19 2019-09-25 MC2 Therapeutics Limited Topical composition comprising calcipotriol and betamethasone dipropionate
EP3834826A4 (en) 2018-08-10 2022-07-27 Koushi Yamaguchi THERAPEUTIC AGENT FOR HUMORAL IMMUNITY-RELATED DISEASES IN THE MATERNO-FETAL RELATIONSHIP
WO2020117134A1 (en) 2018-12-04 2020-06-11 İlko İlaç Sanayi̇ Ve Ti̇caret A.Ş. Stable tacrolimus ointment formulation for topical treatment of skin conditions
US20220062245A1 (en) 2018-12-18 2022-03-03 Koushi Yamaguchi Agent for improving infertility, recurrent miscarriage, and state of pregnancy
CN114767688A (zh) * 2019-09-04 2022-07-22 武汉科福新药有限责任公司 透皮促渗组合物及其在噻吗洛尔制剂中的应用
EP4114357A4 (en) 2020-03-02 2024-05-01 Shanghai Aucta Pharmaceuticals Co Ltd TOPICAL FORMULATIONS WITH MTOR INHIBITORS
CN112022798B (zh) * 2020-08-11 2022-04-29 四川大学华西医院 一种速效他克莫司软膏、制备方法及应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH26083A (en) * 1987-11-09 1992-02-06 Sandoz Ltd 11, 28-dioxa-4-azatricyclo [22.3.1.04.9) octacos-18-ene derivatives and pharmaceutical compositions containing them and method of use thereof
KR0159766B1 (ko) * 1989-10-16 1998-12-01 후지사와 토모키치로 양모제 조성물
US5061700A (en) * 1989-11-16 1991-10-29 Gordon Jay Dow Glyceryl acetate ointment vehicles

Also Published As

Publication number Publication date
GR3022883T3 (en) 1997-06-30
CA2050623A1 (en) 1992-03-05
KR920005987A (ko) 1992-04-27
HUT59002A (en) 1992-04-28
ZA916983B (en) 1992-05-27
DE69125230D1 (de) 1997-04-24
AU656145B2 (en) 1995-01-27
HK1000006A1 (en) 1997-10-03
PT98862A (pt) 1992-08-31
EP0474126A1 (en) 1992-03-11
PH31282A (en) 1998-07-06
RU2079303C1 (ru) 1997-05-20
ES2099112T3 (es) 1997-05-16
CN1069193C (zh) 2001-08-08
JPH0517481A (ja) 1993-01-26
EP0474126B1 (en) 1997-03-19
US5385907A (en) 1995-01-31
HU211470A9 (en) 1995-11-28
IE913085A1 (en) 1992-03-11
JP2526752B2 (ja) 1996-08-21
CA2050623C (en) 2002-02-05
DE69125230T2 (de) 1997-07-10
SG46547A1 (en) 1998-02-20
AU8351591A (en) 1992-03-12
ATE150304T1 (de) 1997-04-15
CN1059468A (zh) 1992-03-18
KR100194240B1 (ko) 1999-06-15
PT98862B (pt) 1999-02-26

Similar Documents

Publication Publication Date Title
DK0474126T3 (zh)
AU653556B2 (en) Suspendible composition and process for preparing the same
DE3777223D1 (de) Feste dispersion der substanz fr-900506.
GR3031179T3 (en) Prolonged-action pharmaceutical preparation.
GR3014946T3 (en) Aqueous liquid composition for external use.
GR3015245T3 (en) Aqueous liquid formulations.