DE69943215D1 - Verfahren zum retten der rna-viren - Google Patents

Verfahren zum retten der rna-viren

Info

Publication number
DE69943215D1
DE69943215D1 DE69943215T DE69943215T DE69943215D1 DE 69943215 D1 DE69943215 D1 DE 69943215D1 DE 69943215 T DE69943215 T DE 69943215T DE 69943215 T DE69943215 T DE 69943215T DE 69943215 D1 DE69943215 D1 DE 69943215D1
Authority
DE
Germany
Prior art keywords
virus
recombinant virus
producing
viruses
mononegavirales
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69943215T
Other languages
English (en)
Inventor
Christopher L Parks
Mohinderjit S Sidhu
Stephen A Udem
Gerald R Kovacs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Wyeth LLC
Original Assignee
Wyeth Holdings LLC
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Holdings LLC, Wyeth LLC filed Critical Wyeth Holdings LLC
Application granted granted Critical
Publication of DE69943215D1 publication Critical patent/DE69943215D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141—Use of virus, viral particle or viral elements as a vector
    • C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/60—Vector systems having a special element relevant for transcription from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69943215T 1998-06-03 1999-06-03 Verfahren zum retten der rna-viren Expired - Lifetime DE69943215D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8780098P 1998-06-03 1998-06-03
PCT/US1999/012292 WO1999063064A1 (en) 1998-06-03 1999-06-03 Novel methods for rescue of rna viruses

Publications (1)

Publication Number Publication Date
DE69943215D1 true DE69943215D1 (de) 2011-04-07

Family

ID=22207342

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69943215T Expired - Lifetime DE69943215D1 (de) 1998-06-03 1999-06-03 Verfahren zum retten der rna-viren

Country Status (14)

Country Link
EP (2) EP1090108B1 (de)
JP (1) JP4625915B2 (de)
KR (2) KR100619319B1 (de)
CN (1) CN1196780C (de)
AT (1) ATE499438T1 (de)
AU (1) AU761234B2 (de)
BR (1) BR9910929A (de)
CA (1) CA2333313C (de)
DE (1) DE69943215D1 (de)
DK (1) DK1090108T3 (de)
ES (1) ES2358315T3 (de)
IL (3) IL140033A0 (de)
MX (1) MX228492B (de)
WO (1) WO1999063064A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7465574B2 (en) 1994-09-30 2008-12-16 Medimmune, Llc Recombinant RSV virus expression systems and vaccines
US6830748B1 (en) 1997-09-26 2004-12-14 Medimmune Vaccines, Inc. Recombinant RSV virus expression systems and vaccines
US6495360B1 (en) * 1999-05-28 2002-12-17 Photogen, Inc. Method for enhanced protein stabilization and for production of cell lines useful for production of such stabilized proteins
US7361496B1 (en) 2000-08-02 2008-04-22 Wyeth Rescue of mumps virus from cDNA
DE60233038D1 (de) * 2002-06-20 2009-09-03 Pasteur Institut Infektiöse cDNA eines zugelassenen Impfstammes des Masern Virus. Verwendung in immunogenen Zusammensetzungen
BRPI0411247A (pt) * 2003-06-09 2006-07-25 Wyeth Corp processo melhorado para a recuperação de vìrus de rna de filamento negativo não segmentado partindo do cdna
CA2778332A1 (en) † 2009-10-20 2011-04-28 Novartis Ag Improved reverse genetics methods for virus rescue
EP2780034A1 (de) 2011-11-14 2014-09-24 Crucell Holland B.V. Heterologe prime-boost-impfung mit auf masernviren basierten impfstoffen
CN102807989B (zh) * 2012-08-01 2014-04-23 中国人民解放军军事医学科学院军事兽医研究所 犬科和/或猫科动物疫病重组活载体疫苗的制备方法
WO2016157208A1 (en) * 2015-03-27 2016-10-06 Cadila Healthcare Limited Recombinant mumps virus jeryl lynn 2 based vaccine
CN105039388B (zh) * 2015-06-30 2019-06-18 浙江大学 重组单链负义植物病毒侵染性克隆构建方法及质粒和病毒
CN107058359B (zh) * 2017-04-14 2019-08-13 北京交通大学 一种抗呼吸道合胞病毒药物的高通量筛选方法和应用
WO2018208960A1 (en) * 2017-05-09 2018-11-15 Dimension Therapeutics, Inc. Scalable method for producing transfection reagents
CN111849927B (zh) * 2020-06-28 2022-07-08 浙江大学 高效产生重组不分节段负义rna病毒的方法及重组病毒
CN117625688B (zh) * 2024-01-26 2024-04-30 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） B亚型禽偏肺病毒反向遗传操作系统及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990009192A1 (en) * 1989-02-14 1990-08-23 Massachusetts Institute Of Technology Inhibiting transformation of cells having elevated purine metabolic enzyme activity
AU672359B2 (en) * 1991-03-07 1996-10-03 Virogenetics Corporation Genetically engineered vaccine strain
JPH06237773A (ja) * 1992-12-22 1994-08-30 Tonen Corp ポックスウイルスのａ型封入体（ａｔｉ）プロモーター及び前期プロモーターを含んで成る外来遺伝子発現ベクター
ATE181112T1 (de) 1995-08-09 1999-06-15 Schweiz Serum & Impfinst Dem genom von minussträngigen rna-viren entsprechende cdna und verfahren zur herstellung von infektiösen minussträngigen rna-viren
CA2230033C (en) * 1995-09-27 2010-01-26 Peter L. Collins Production of infectious respiratory syncytial virus from cloned nucleotide sequences
AU4427897A (en) * 1996-09-27 1998-04-17 American Cyanamid Company 3' genomic promoter region and polymerase gene mutations responsible for att enuation in viruses of the order designated mononegavirales
US5871803A (en) 1997-05-30 1999-02-16 Campbell Soup Company Salt flavor enhancing compositions, food products including such compositions, and methods for preparing such products

Also Published As

Publication number Publication date
KR100579662B1 (ko) 2006-05-12
KR100619319B1 (ko) 2006-09-06
AU4414499A (en) 1999-12-20
EP1995310B1 (de) 2013-04-24
DK1090108T3 (da) 2011-04-26
ES2358315T3 (es) 2011-05-09
ATE499438T1 (de) 2011-03-15
KR20010052498A (ko) 2001-06-25
CN1196780C (zh) 2005-04-13
CA2333313C (en) 2011-11-08
MXPA00011420A (es) 2001-04-01
IL182512A (en) 2012-07-31
IL140033A (en) 2010-05-17
MX228492B (es) 2005-06-14
IL182512A0 (en) 2007-09-20
JP2002517189A (ja) 2002-06-18
KR20060021943A (ko) 2006-03-08
EP1090108B1 (de) 2011-02-23
WO1999063064A1 (en) 1999-12-09
EP1995310A1 (de) 2008-11-26
BR9910929A (pt) 2001-02-20
CN1303426A (zh) 2001-07-11
AU761234B2 (en) 2003-05-29
EP1090108A1 (de) 2001-04-11
IL140033A0 (en) 2002-02-10
CA2333313A1 (en) 1999-12-09
JP4625915B2 (ja) 2011-02-02

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