ATE369435T1 - Paramyxoviren, die eine modifizierte transkriptionsstartsequenz umfassen - Google Patents

Paramyxoviren, die eine modifizierte transkriptionsstartsequenz umfassen

Info

Publication number
ATE369435T1
ATE369435T1 AT00956962T AT00956962T ATE369435T1 AT E369435 T1 ATE369435 T1 AT E369435T1 AT 00956962 T AT00956962 T AT 00956962T AT 00956962 T AT00956962 T AT 00956962T AT E369435 T1 ATE369435 T1 AT E369435T1
Authority
AT
Austria
Prior art keywords
sequence
gene
vectors
expression
transcription
Prior art date
Application number
AT00956962T
Other languages
English (en)
Inventor
Yoshiyuki Nagai
Atsushi Kato
Mamoru Hasegawa
Original Assignee
Dnavec Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dnavec Research Inc filed Critical Dnavec Research Inc
Application granted granted Critical
Publication of ATE369435T1 publication Critical patent/ATE369435T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18811—Sendai virus
    • C12N2760/18822—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18811—Sendai virus
    • C12N2760/18841—Use of virus, viral particle or viral elements as a vector
    • C12N2760/18843—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
AT00956962T 1999-09-06 2000-09-06 Paramyxoviren, die eine modifizierte transkriptionsstartsequenz umfassen ATE369435T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP25223199 1999-09-06

Publications (1)

Publication Number Publication Date
ATE369435T1 true ATE369435T1 (de) 2007-08-15

Family

ID=17234351

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00956962T ATE369435T1 (de) 1999-09-06 2000-09-06 Paramyxoviren, die eine modifizierte transkriptionsstartsequenz umfassen

Country Status (13)

Country Link
US (1) US7144579B2 (de)
EP (1) EP1211318B1 (de)
JP (1) JP3748535B2 (de)
KR (1) KR100776086B1 (de)
CN (1) CN1367839A (de)
AT (1) ATE369435T1 (de)
AU (1) AU6872000A (de)
CA (1) CA2376106A1 (de)
DE (1) DE60035885T2 (de)
DK (1) DK1211318T3 (de)
ES (1) ES2288866T3 (de)
HK (1) HK1047450A1 (de)
WO (1) WO2001018223A1 (de)

Families Citing this family (37)

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US6490775B1 (en) * 1999-04-23 2002-12-10 Veri-Tek Inc. Press operation verification system
US20030166252A1 (en) * 1999-05-18 2003-09-04 Kaio Kitazato Paramyxovirus-derived RNP
US7226786B2 (en) * 1999-05-18 2007-06-05 Dnavec Research Inc. Envelope gene-deficient Paramyxovirus vector
US7314614B1 (en) 1999-11-02 2008-01-01 Dnavec Research, Inc. Recombinant sendai virus vector for introducing exogenous genes to airway epithelia
KR100774796B1 (ko) * 2000-01-19 2007-11-07 가부시키가이샤 디나벡크 겐큐쇼 파라믹소바이러스 벡터의 혈관으로의 유전자 도입용도
US20020002143A1 (en) 2000-03-30 2002-01-03 Munehide Kano AIDS virus vaccines using sendai virus vector
KR100807016B1 (ko) * 2000-06-01 2008-02-25 가부시키가이샤 디나벡크 겐큐쇼 헤마글루티닌 활성을 갖는 막단백질을 포함하는 슈도타입레트로바이러스 벡터
KR20030014392A (ko) * 2000-06-27 2003-02-17 가부시키가이샤 디나벡크 겐큐쇼 신장세포에 유전자를 도입하기 위한 바이러스 벡터
WO2002031138A1 (en) * 2000-10-06 2002-04-18 Dnavec Research Inc. Paramyxovirus vector for transferring foreign gene into skeletal muscle
JP2002142770A (ja) 2000-11-08 2002-05-21 Dnavec Research Inc 循環系への遺伝子送達用パラミクソウイルスベクター
US20040265272A1 (en) * 2001-09-28 2004-12-30 Aikichi Iwamoto Mammalian cell-infecting virus vector encoding epitope-bound beta2m and utilization thereof
WO2003092738A1 (en) * 2002-04-30 2003-11-13 Dnavec Research Inc. Drug- or gene-carrier composition having lowered hemagglutinin activity
JPWO2004022731A1 (ja) * 2002-09-04 2005-12-22 株式会社ディナベック研究所 シアル酸結合活性を有する膜蛋白質をエンベロープに含むウイルスベクターをグラム陽性菌由来ノイラミニダーゼを用いて製造する方法
KR20050062572A (ko) * 2002-10-01 2005-06-23 가부시키가이샤 디나벡크 겐큐쇼 ＴＡＰ 활성의 저해에 의해 ＭＨＣ ｃｌａｓｓ Ⅰ에 의한외래 에피토프의 제시를 증강시키는 방법
AU2003275581A1 (en) * 2002-10-24 2004-05-13 Dnavec Research Inc. Method of transferring gene into t cells
CN1768145A (zh) * 2003-01-31 2006-05-03 株式会社载体研究所 编码核酶的副粘病毒载体及其应用
EP1642966B1 (de) * 2003-06-30 2010-03-03 Dnavec Research Inc. Negativ-strang rna-virus-vektoren, welche ein gen mit veränderten hypermutierbaren regionen tragen
WO2005071085A1 (ja) * 2004-01-22 2005-08-04 Dnavec Research Inc. ウイルスベクターの製造方法
CA2553976C (en) 2004-01-22 2013-09-24 Dnavec Research Inc. Method for producing minus-strand rna viral vectors using hybrid promoter comprising cytomegalovirus enhancer and chicken .beta.-actin promoter
CA2612168A1 (en) 2005-06-14 2006-12-21 Dnavec Corporation Methods for producing antibodies
HUE028512T2 (en) * 2005-10-28 2016-12-28 Id Pharma Co Ltd Gene transfer to airway epithelial stem cell using RNA virus spike protein pseudotyped lentiviral vector
KR20080094910A (ko) 2006-01-17 2008-10-27 디나벡크 가부시키가이샤 신규 단백질 발현계
KR20090027693A (ko) 2006-05-31 2009-03-17 디나벡크 가부시키가이샤 알츠하이머병 치료제
CN101646768A (zh) 2007-02-07 2010-02-10 生物载体株式会社 减毒负链rna病毒
WO2008129971A1 (ja) * 2007-04-13 2008-10-30 National Institute Of Advanced Industrial Science And Technology 改良された持続感染型センダイウイルスベクター
EP2143794A1 (de) 2007-04-27 2010-01-13 Kyushu University, National University Corporation Viraler vektor für gentherapie
DK2322611T3 (en) 2008-07-16 2016-09-05 Ip Pharma Co Ltd A process for producing reprogrammed cells using chromosomally non-integrated viral vector
CN102272302B (zh) 2008-10-31 2015-04-15 生物载体株式会社 增强重组蛋白表达的方法
JP5697044B2 (ja) 2010-01-08 2015-04-08 国立大学法人京都大学 タウオパチー治療用ワクチン
JP5908838B2 (ja) 2010-08-30 2016-04-26 株式会社Ｉｄファーマ 多能性幹細胞を誘導するための組成物およびその使用
US10975358B2 (en) 2013-09-24 2021-04-13 Id Pharma Co., Ltd. Method for improving efficiency of inducing pluripotent stem cell
US11103574B2 (en) 2016-11-17 2021-08-31 Japan, as represented by the Director-General of National Institute of Infectious Disease Infectious disease vaccine using non-infectious paramyxovirus particle
EP3656858A4 (de) 2017-07-21 2021-04-21 I'rom Group Co., Ltd. Polynukleotid zur modifizierung von zielsequenzen und dessen verwendung
WO2019142933A1 (ja) 2018-01-22 2019-07-25 国立感染症研究所長が代表する日本国 選択的ｃｄ８陽性ｔ細胞誘導ワクチン抗原
CN111733170A (zh) * 2020-07-01 2020-10-02 青岛农业大学 一种表达荧光素酶的重组犬麻疹病毒
JP7808298B2 (ja) 2020-09-04 2026-01-29 Ｈｅａｒｔｓｅｅｄ株式会社 ｉＰＳ細胞の品質改善剤、ｉＰＳ細胞の製造方法、ｉＰＳ細胞、及びｉＰＳ細胞製造用組成物
WO2022138964A1 (ja) 2020-12-25 2022-06-30 国立大学法人京都大学 体細胞からのナイーブ型ヒトｉＰＳ細胞製造方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100754091B1 (ko) * 1995-10-31 2007-08-31 가부시끼가이샤 디나벡 겡뀨쇼 자율 복제 능력을 갖는 (-)쇄 ｒｎａ 바이러스 벡터
AU7335296A (en) * 1995-11-01 1997-05-22 Dnavec Research Inc. Recombinant sendai virus
ATE451451T1 (de) * 1996-07-15 2009-12-15 Us Gov Health & Human Serv Herstellung von attenuierten respiratorischen syncytialvirus-impfstoffen aus klonierten nukleotidsequenzen
US6828138B1 (en) * 1998-08-11 2004-12-07 Dnavec Research Inc. Recombinant sendai virus vector including a gene encoding a chemokine
US20030166252A1 (en) * 1999-05-18 2003-09-04 Kaio Kitazato Paramyxovirus-derived RNP
US7226786B2 (en) * 1999-05-18 2007-06-05 Dnavec Research Inc. Envelope gene-deficient Paramyxovirus vector
KR100774796B1 (ko) * 2000-01-19 2007-11-07 가부시키가이샤 디나벡크 겐큐쇼 파라믹소바이러스 벡터의 혈관으로의 유전자 도입용도
US20020002143A1 (en) * 2000-03-30 2002-01-03 Munehide Kano AIDS virus vaccines using sendai virus vector
CA2322057A1 (en) * 2000-05-18 2001-11-18 Dnavec Research Inc. Paramyxovirus vectors used for transfer of foreign genes
KR100807016B1 (ko) * 2000-06-01 2008-02-25 가부시키가이샤 디나벡크 겐큐쇼 헤마글루티닌 활성을 갖는 막단백질을 포함하는 슈도타입레트로바이러스 벡터
KR20030014392A (ko) 2000-06-27 2003-02-17 가부시키가이샤 디나벡크 겐큐쇼 신장세포에 유전자를 도입하기 위한 바이러스 벡터
WO2002031138A1 (en) 2000-10-06 2002-04-18 Dnavec Research Inc. Paramyxovirus vector for transferring foreign gene into skeletal muscle
JP2002142770A (ja) 2000-11-08 2002-05-21 Dnavec Research Inc 循環系への遺伝子送達用パラミクソウイルスベクター
DE60133767T2 (de) * 2000-11-27 2009-06-25 Dnavec Research Inc., Tsukuba Für fibroblasten-wachstumsfaktor 2 (fgf2) kodierender paramyxovirus-vektor und dessen verwendung

Also Published As

Publication number Publication date
DE60035885T2 (de) 2008-05-08
ES2288866T3 (es) 2008-02-01
HK1047450A1 (zh) 2003-02-21
EP1211318A1 (de) 2002-06-05
WO2001018223A1 (en) 2001-03-15
DE60035885D1 (de) 2007-09-20
JP3748535B2 (ja) 2006-02-22
US20040121308A1 (en) 2004-06-24
CA2376106A1 (en) 2001-03-15
KR20020013565A (ko) 2002-02-20
EP1211318A4 (de) 2003-08-13
CN1367839A (zh) 2002-09-04
EP1211318B1 (de) 2007-08-08
DK1211318T3 (da) 2007-11-12
AU6872000A (en) 2001-04-10
KR100776086B1 (ko) 2007-11-15
US7144579B2 (en) 2006-12-05

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