HK1047450A1 - 含有已改變的轉錄起始序列的副粘病毒 - Google Patents

含有已改變的轉錄起始序列的副粘病毒

Info

Publication number
HK1047450A1
HK1047450A1 HK02108577.2A HK02108577A HK1047450A1 HK 1047450 A1 HK1047450 A1 HK 1047450A1 HK 02108577 A HK02108577 A HK 02108577A HK 1047450 A1 HK1047450 A1 HK 1047450A1
Authority
HK
Hong Kong
Prior art keywords
sequence
gene
vectors
expression
transcription
Prior art date
Application number
HK02108577.2A
Other languages
English (en)
Inventor
永井美之
加藤篤
長谷川護
Original Assignee
株式會社載體研究所
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 株式會社載體研究所 filed Critical 株式會社載體研究所
Publication of HK1047450A1 publication Critical patent/HK1047450A1/zh

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18811—Sendai virus
    • C12N2760/18822—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18811—Sendai virus
    • C12N2760/18841—Use of virus, viral particle or viral elements as a vector
    • C12N2760/18843—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
HK02108577.2A 1999-09-06 2002-11-28 含有已改變的轉錄起始序列的副粘病毒 HK1047450A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP25223199 1999-09-06
PCT/JP2000/006051 WO2001018223A1 (fr) 1999-09-06 2000-09-06 Paramoxyvirus possedant une sequence d'initiation de transcription modifiee

Publications (1)

Publication Number Publication Date
HK1047450A1 true HK1047450A1 (zh) 2003-02-21

Family

ID=17234351

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02108577.2A HK1047450A1 (zh) 1999-09-06 2002-11-28 含有已改變的轉錄起始序列的副粘病毒

Country Status (13)

Country Link
US (1) US7144579B2 (zh)
EP (1) EP1211318B1 (zh)
JP (1) JP3748535B2 (zh)
KR (1) KR100776086B1 (zh)
CN (1) CN1367839A (zh)
AT (1) ATE369435T1 (zh)
AU (1) AU6872000A (zh)
CA (1) CA2376106A1 (zh)
DE (1) DE60035885T2 (zh)
DK (1) DK1211318T3 (zh)
ES (1) ES2288866T3 (zh)
HK (1) HK1047450A1 (zh)
WO (1) WO2001018223A1 (zh)

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US6490775B1 (en) * 1999-04-23 2002-12-10 Veri-Tek Inc. Press operation verification system
US7226786B2 (en) * 1999-05-18 2007-06-05 Dnavec Research Inc. Envelope gene-deficient Paramyxovirus vector
US20030166252A1 (en) * 1999-05-18 2003-09-04 Kaio Kitazato Paramyxovirus-derived RNP
US7314614B1 (en) 1999-11-02 2008-01-01 Dnavec Research, Inc. Recombinant sendai virus vector for introducing exogenous genes to airway epithelia
US20030170210A1 (en) * 2000-01-19 2003-09-11 Ichiro Masaki Use of paramyxovirus vector in gene transfer into blood vessel
US20020002143A1 (en) 2000-03-30 2002-01-03 Munehide Kano AIDS virus vaccines using sendai virus vector
CA2413995C (en) * 2000-06-01 2013-08-13 Dnavec Research Inc. Pseudotype retroviral vectors containing membrane proteins having hemagglutinin activity
AU2001266337A1 (en) * 2000-06-27 2002-01-08 Dnavec Research Inc. Virus vector for transferring gene into renal cells
JPWO2002031138A1 (ja) * 2000-10-06 2004-02-19 株式会社ディナベック研究所 骨格筋に外来遺伝子を導入するためのパラミクソウイルスベクター
JP2002142770A (ja) * 2000-11-08 2002-05-21 Dnavec Research Inc 循環系への遺伝子送達用パラミクソウイルスベクター
WO2003029475A1 (en) * 2001-09-28 2003-04-10 Dnavec Research Inc. MAMMALIAN CELL-INFECTING VIRUS VECTOR ENCODING EPITOPE-BOUND β2m AND UTILIZATION THEREOF
KR20040104673A (ko) * 2002-04-30 2004-12-10 가부시키가이샤 디나벡크 겐큐쇼 헤마글루티닌 활성을 저하시킨 약제 또는 유전자 운반 조성물
CA2497475A1 (en) * 2002-09-04 2004-03-18 Dnavec Research Inc. Methods of producing a viral vector comprising a membrane protein that binds to sialic acid as a component of the envelope using neuraminidase derived from gram-positive bacteria
AU2003268721A1 (en) * 2002-10-01 2004-04-23 Dnavec Research Inc. Method of strengthening foreign epitope presentation by mhc class i by inhibiting tap activity
US20060104950A1 (en) * 2002-10-24 2006-05-18 Shinji Okano Methods of Tranducing genes into T cells
CN1768145A (zh) * 2003-01-31 2006-05-03 株式会社载体研究所 编码核酶的副粘病毒载体及其应用
CN1816618A (zh) * 2003-06-30 2006-08-09 株式会社载体研究所 携带具有改变的高变区的基因的负链rna病毒载体
EP1717317A4 (en) 2004-01-22 2009-02-11 Dnavec Research Inc METHOD OF GENERATING VIRAL NEGATIVE STRAND RNA VECTORS USING A HYBRID PROMOTER COMPRISING THE CYTOMEGALOVIRUS ENHANCER AND THE BETA ACTIN PROMOTER FROM CHICKEN
WO2005071085A1 (ja) * 2004-01-22 2005-08-04 Dnavec Research Inc. ウイルスベクターの製造方法
EP1916298B1 (en) 2005-06-14 2011-12-28 Dnavec Corporation Methods for producing monoclonal antibodies
WO2007049752A1 (ja) 2005-10-28 2007-05-03 Dnavec Corporation Rnaウイルスまたはdnaウイルスのスパイクタンパク質でシュードタイプ化したレンチウイルスベクターを用いた気道上皮幹細胞への遺伝子導入
CA2636600A1 (en) 2006-01-17 2007-07-26 Dnavec Corporation Novel protein expression system
US20090246170A1 (en) 2006-05-31 2009-10-01 Dnavec Corporation Therapeutic Agent For Alzheimer's Disease
KR20090114431A (ko) 2007-02-07 2009-11-03 디나벡크 가부시키가이샤 약독화 마이너스 가닥 ｒｎａ 바이러스
US9145564B2 (en) * 2007-04-13 2015-09-29 National Institute Of Advanced Industrial Science And Technology Persistently infective Sendai virus vector
US20100203027A1 (en) 2007-04-27 2010-08-12 Kyushu Univeristy National University Viral vector for gene therapy
US9127256B2 (en) 2008-07-16 2015-09-08 Dnavec Corporation Method for production of reprogrammed cell using chromosomally unintegrated virus vector
JPWO2010050586A1 (ja) 2008-10-31 2012-03-29 ディナベック株式会社 組み換え蛋白質の発現を増強する方法
JP5697044B2 (ja) 2010-01-08 2015-04-08 国立大学法人京都大学 タウオパチー治療用ワクチン
CN103189508B (zh) 2010-08-30 2016-08-10 生物载体株式会社 用于诱导多能性干细胞的组合物及其用途
US10975358B2 (en) 2013-09-24 2021-04-13 Id Pharma Co., Ltd. Method for improving efficiency of inducing pluripotent stem cell
WO2018092887A1 (ja) 2016-11-17 2018-05-24 国立感染症研究所長が代表する日本国 非感染性パラミクソウイルス粒子を用いた感染症ワクチン
JP6947825B2 (ja) 2017-07-21 2021-10-13 株式会社 アイロムグループ 標的配列を改変するためのポリヌクレオチドおよびその使用
CN112135908A (zh) 2018-01-22 2020-12-25 国立传染病研究所长代表日本国 选择性cd8阳性t细胞诱导疫苗抗原
CN111733170A (zh) * 2020-07-01 2020-10-02 青岛农业大学 一种表达荧光素酶的重组犬麻疹病毒
JPWO2022050419A1 (zh) 2020-09-04 2022-03-10
EP4269571A1 (en) 2020-12-25 2023-11-01 Kyoto University Method for producing naive human ips cells from somatic cells

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ATE298789T1 (de) 1995-10-31 2005-07-15 Dnavec Research Inc Negativstrand rna virus mit selbständiger replikationsaktivität
ATE470704T1 (de) 1995-11-01 2010-06-15 Dnavec Research Inc Rekombinantes sendai-virus
BR9710363A (pt) * 1996-07-15 2000-01-11 Us Gov Health & Human Serv "vìrus sincicial respirátorio recombinante infeccioso isolado, partìcula do mesmo, processos para estimular o sistema imunológico de um indivìduo para induzir proteção contra o vìrus sincicial respiratório e para produzir uma partìcula de vìrus sincicial respiratório recombinante, vacina para induzir proteção contra o vìrus sincicial respiratório recombinante composição e ceta de vìrus sincicial respiratório recombinante"
US6828138B1 (en) 1998-08-11 2004-12-07 Dnavec Research Inc. Recombinant sendai virus vector including a gene encoding a chemokine
US7226786B2 (en) 1999-05-18 2007-06-05 Dnavec Research Inc. Envelope gene-deficient Paramyxovirus vector
US20030166252A1 (en) 1999-05-18 2003-09-04 Kaio Kitazato Paramyxovirus-derived RNP
US20030170210A1 (en) 2000-01-19 2003-09-11 Ichiro Masaki Use of paramyxovirus vector in gene transfer into blood vessel
US20020002143A1 (en) 2000-03-30 2002-01-03 Munehide Kano AIDS virus vaccines using sendai virus vector
CA2322057A1 (en) 2000-05-18 2001-11-18 Dnavec Research Inc. Paramyxovirus vectors used for transfer of foreign genes
CA2413995C (en) 2000-06-01 2013-08-13 Dnavec Research Inc. Pseudotype retroviral vectors containing membrane proteins having hemagglutinin activity
AU2001266337A1 (en) 2000-06-27 2002-01-08 Dnavec Research Inc. Virus vector for transferring gene into renal cells
JPWO2002031138A1 (ja) 2000-10-06 2004-02-19 株式会社ディナベック研究所 骨格筋に外来遺伝子を導入するためのパラミクソウイルスベクター
JP2002142770A (ja) 2000-11-08 2002-05-21 Dnavec Research Inc 循環系への遺伝子送達用パラミクソウイルスベクター
ES2305138T3 (es) 2000-11-27 2008-11-01 Dnavec Research Inc. Vector de paramixovirus que codifica factor 2 de crecimiento de fibroblastos (fgf2) y uso del mismo.

Also Published As

Publication number Publication date
DE60035885T2 (de) 2008-05-08
WO2001018223A1 (fr) 2001-03-15
ES2288866T3 (es) 2008-02-01
KR20020013565A (ko) 2002-02-20
EP1211318A1 (en) 2002-06-05
KR100776086B1 (ko) 2007-11-15
AU6872000A (en) 2001-04-10
ATE369435T1 (de) 2007-08-15
EP1211318A4 (en) 2003-08-13
DE60035885D1 (de) 2007-09-20
JP3748535B2 (ja) 2006-02-22
DK1211318T3 (da) 2007-11-12
US7144579B2 (en) 2006-12-05
CN1367839A (zh) 2002-09-04
CA2376106A1 (en) 2001-03-15
US20040121308A1 (en) 2004-06-24
EP1211318B1 (en) 2007-08-08

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