ATE499438T1 - Verfahren zum retten der rna-viren - Google Patents
Verfahren zum retten der rna-virenInfo
- Publication number
- ATE499438T1 ATE499438T1 AT99927175T AT99927175T ATE499438T1 AT E499438 T1 ATE499438 T1 AT E499438T1 AT 99927175 T AT99927175 T AT 99927175T AT 99927175 T AT99927175 T AT 99927175T AT E499438 T1 ATE499438 T1 AT E499438T1
- Authority
- AT
- Austria
- Prior art keywords
- virus
- recombinant virus
- producing
- viruses
- mononegavirales
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title abstract 7
- 238000000034 method Methods 0.000 title abstract 3
- 241000711513 Mononegavirales Species 0.000 abstract 3
- 241000712079 Measles morbillivirus Species 0.000 abstract 2
- 241000725643 Respiratory syncytial virus Species 0.000 abstract 2
- 241001493065 dsRNA viruses Species 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 230000035897 transcription Effects 0.000 abstract 2
- 238000013518 transcription Methods 0.000 abstract 2
- 239000013598 vector Substances 0.000 abstract 2
- 230000002238 attenuated effect Effects 0.000 abstract 1
- 230000004186 co-expression Effects 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 238000003306 harvesting Methods 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000002458 infectious effect Effects 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000011084 recovery Methods 0.000 abstract 1
- 230000010076 replication Effects 0.000 abstract 1
- 230000035939 shock Effects 0.000 abstract 1
- 238000001890 transfection Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/60—Vector systems having a special element relevant for transcription from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
- C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
- C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
Landscapes
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8780098P | 1998-06-03 | 1998-06-03 | |
| PCT/US1999/012292 WO1999063064A1 (en) | 1998-06-03 | 1999-06-03 | Novel methods for rescue of rna viruses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE499438T1 true ATE499438T1 (de) | 2011-03-15 |
Family
ID=22207342
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99927175T ATE499438T1 (de) | 1998-06-03 | 1999-06-03 | Verfahren zum retten der rna-viren |
Country Status (14)
| Country | Link |
|---|---|
| EP (2) | EP1995310B1 (de) |
| JP (1) | JP4625915B2 (de) |
| KR (2) | KR100579662B1 (de) |
| CN (1) | CN1196780C (de) |
| AT (1) | ATE499438T1 (de) |
| AU (1) | AU761234B2 (de) |
| BR (1) | BR9910929A (de) |
| CA (1) | CA2333313C (de) |
| DE (1) | DE69943215D1 (de) |
| DK (1) | DK1090108T3 (de) |
| ES (1) | ES2358315T3 (de) |
| IL (3) | IL140033A0 (de) |
| MX (1) | MX228492B (de) |
| WO (1) | WO1999063064A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7465574B2 (en) | 1994-09-30 | 2008-12-16 | Medimmune, Llc | Recombinant RSV virus expression systems and vaccines |
| US6830748B1 (en) | 1997-09-26 | 2004-12-14 | Medimmune Vaccines, Inc. | Recombinant RSV virus expression systems and vaccines |
| US6495360B1 (en) * | 1999-05-28 | 2002-12-17 | Photogen, Inc. | Method for enhanced protein stabilization and for production of cell lines useful for production of such stabilized proteins |
| US7361496B1 (en) | 2000-08-02 | 2008-04-22 | Wyeth | Rescue of mumps virus from cDNA |
| DK1375512T3 (da) * | 2002-06-20 | 2009-10-26 | Pasteur Institut | Infektiös cDNA af en godkendt vaccinestamme af mæslingevirus. Anvendelse til immunogene sammensætninger |
| KR101020532B1 (ko) * | 2003-06-09 | 2011-03-09 | 와이어쓰 엘엘씨 | ｃＤＮＡ로부터의 비분절 네가티브 쇄 ＲＮＡ 바이러스의 회수를 위한 개선된 방법 |
| SI2491117T1 (sl) * | 2009-10-20 | 2014-03-31 | Novartis Ag | Izboljšani postopki reverzne genetike za pridobivanje virusov |
| WO2013074501A1 (en) | 2011-11-14 | 2013-05-23 | Crucell Holland B.V. | Heterologous prime-boost immunization using measles virus-based vaccines |
| CN102807989B (zh) * | 2012-08-01 | 2014-04-23 | 中国人民解放军军事医学科学院军事兽医研究所 | 犬科和/或猫科动物疫病重组活载体疫苗的制备方法 |
| PT3274447T (pt) * | 2015-03-27 | 2020-01-21 | Cadila Healthcare Ltd | Vacina baseada no vírus da papeira recombinante jeryl lynn 2 |
| CN105039388B (zh) * | 2015-06-30 | 2019-06-18 | 浙江大学 | 重组单链负义植物病毒侵染性克隆构建方法及质粒和病毒 |
| CN107058359B (zh) * | 2017-04-14 | 2019-08-13 | 北京交通大学 | 一种抗呼吸道合胞病毒药物的高通量筛选方法和应用 |
| US12487152B2 (en) | 2017-05-09 | 2025-12-02 | Ultragenyx Pharmaceutical Inc. | Scalable method for producing transfection reagents |
| CN111849927B (zh) * | 2020-06-28 | 2022-07-08 | 浙江大学 | 高效产生重组不分节段负义rna病毒的方法及重组病毒 |
| WO2025072889A1 (en) * | 2023-09-28 | 2025-04-03 | E & E Bioclub Llc | Helper-free rescue system for negative-strand rna viruses |
| CN117625688B (zh) * | 2024-01-26 | 2024-04-30 | 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） | B亚型禽偏肺病毒反向遗传操作系统及其应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE161188T1 (de) * | 1989-02-14 | 1998-01-15 | Massachusetts Inst Technology | Hemmung der transformation der zellen mit erhöhter purin-metabolischer enzymaktivität |
| JP3602530B2 (ja) * | 1991-03-07 | 2004-12-15 | ヴァイロジェネティクス コーポレイション | 遺伝子操作したワクチン菌株 |
| JPH06237773A (ja) * | 1992-12-22 | 1994-08-30 | Tonen Corp | ポックスウイルスのａ型封入体（ａｔｉ）プロモーター及び前期プロモーターを含んで成る外来遺伝子発現ベクター |
| ATE181112T1 (de) | 1995-08-09 | 1999-06-15 | Schweiz Serum & Impfinst | Dem genom von minussträngigen rna-viren entsprechende cdna und verfahren zur herstellung von infektiösen minussträngigen rna-viren |
| US6264957B1 (en) * | 1995-09-27 | 2001-07-24 | The United States Of America As Represented By The Department Of Health And Human Services | Product of infectious respiratory syncytial virus from cloned nucleotide sequences |
| KR20000048628A (ko) | 1996-09-27 | 2000-07-25 | 윌리암 에이취 캘넌, 에곤 이 버그 | 모노네가비랄레스 목의 바이러스에서 감쇠를 책임지는 3' 게놈프로모터 영역 및 폴리머라제 유전자 돌연변이 |
| US5871803A (en) | 1997-05-30 | 1999-02-16 | Campbell Soup Company | Salt flavor enhancing compositions, food products including such compositions, and methods for preparing such products |
-
1999
- 1999-06-03 WO PCT/US1999/012292 patent/WO1999063064A1/en not_active Ceased
- 1999-06-03 CN CNB998067172A patent/CN1196780C/zh not_active Expired - Fee Related
- 1999-06-03 ES ES99927175T patent/ES2358315T3/es not_active Expired - Lifetime
- 1999-06-03 DK DK99927175.2T patent/DK1090108T3/da active
- 1999-06-03 EP EP08006339.9A patent/EP1995310B1/de not_active Expired - Lifetime
- 1999-06-03 EP EP99927175A patent/EP1090108B1/de not_active Expired - Lifetime
- 1999-06-03 AU AU44144/99A patent/AU761234B2/en not_active Ceased
- 1999-06-03 JP JP2000552260A patent/JP4625915B2/ja not_active Expired - Fee Related
- 1999-06-03 DE DE69943215T patent/DE69943215D1/de not_active Expired - Lifetime
- 1999-06-03 IL IL14003399A patent/IL140033A0/xx unknown
- 1999-06-03 BR BR9910929-8A patent/BR9910929A/pt not_active IP Right Cessation
- 1999-06-03 KR KR20007013629A patent/KR100579662B1/ko not_active Expired - Fee Related
- 1999-06-03 KR KR1020067003345A patent/KR100619319B1/ko not_active Expired - Fee Related
- 1999-06-03 AT AT99927175T patent/ATE499438T1/de active
- 1999-06-03 CA CA2333313A patent/CA2333313C/en not_active Expired - Fee Related
-
2000
- 2000-11-21 MX MXPA00011420 patent/MX228492B/es active IP Right Grant
- 2000-12-01 IL IL140033A patent/IL140033A/en not_active IP Right Cessation
-
2007
- 2007-04-12 IL IL182512A patent/IL182512A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2333313C (en) | 2011-11-08 |
| IL182512A0 (en) | 2007-09-20 |
| CN1196780C (zh) | 2005-04-13 |
| DE69943215D1 (de) | 2011-04-07 |
| EP1090108A1 (de) | 2001-04-11 |
| WO1999063064A1 (en) | 1999-12-09 |
| KR20060021943A (ko) | 2006-03-08 |
| ES2358315T3 (es) | 2011-05-09 |
| JP2002517189A (ja) | 2002-06-18 |
| KR20010052498A (ko) | 2001-06-25 |
| MXPA00011420A (es) | 2001-04-01 |
| EP1995310A1 (de) | 2008-11-26 |
| EP1995310B1 (de) | 2013-04-24 |
| AU4414499A (en) | 1999-12-20 |
| BR9910929A (pt) | 2001-02-20 |
| MX228492B (es) | 2005-06-14 |
| KR100579662B1 (ko) | 2006-05-12 |
| IL140033A (en) | 2010-05-17 |
| IL182512A (en) | 2012-07-31 |
| EP1090108B1 (de) | 2011-02-23 |
| DK1090108T3 (da) | 2011-04-26 |
| KR100619319B1 (ko) | 2006-09-06 |
| CA2333313A1 (en) | 1999-12-09 |
| JP4625915B2 (ja) | 2011-02-02 |
| IL140033A0 (en) | 2002-02-10 |
| CN1303426A (zh) | 2001-07-11 |
| AU761234B2 (en) | 2003-05-29 |
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| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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