DE69931409T2 - Therapeutische Verwendung als Histamin-H3-Rezeptor Liganden von Alkylaminen, die kein Imidazole enthalten - Google Patents
Therapeutische Verwendung als Histamin-H3-Rezeptor Liganden von Alkylaminen, die kein Imidazole enthalten Download PDFInfo
- Publication number
- DE69931409T2 DE69931409T2 DE69931409T DE69931409T DE69931409T2 DE 69931409 T2 DE69931409 T2 DE 69931409T2 DE 69931409 T DE69931409 T DE 69931409T DE 69931409 T DE69931409 T DE 69931409T DE 69931409 T2 DE69931409 T2 DE 69931409T2
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- Prior art keywords
- alkyl
- group
- propyl
- compound
- ether
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
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| EP98401944A EP0978512A1 (en) | 1998-07-29 | 1998-07-29 | Non-imidazole aryloxy (or arylthio) alkylamines as histamine H3-receptor antagonists and their therapeutic applications |
| EP98401944 | 1998-07-29 | ||
| EP98403351 | 1998-12-31 | ||
| EP98403351A EP0982300A3 (en) | 1998-07-29 | 1998-12-31 | Non-imidazole alkylamines as histamine H3 - receptor ligands and their therapeutic applications |
Publications (2)
| Publication Number | Publication Date |
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| DE69931409D1 DE69931409D1 (de) | 2006-06-22 |
| DE69931409T2 true DE69931409T2 (de) | 2006-11-02 |
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| Application Number | Title | Priority Date | Filing Date |
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| DE69931409T Expired - Lifetime DE69931409T2 (de) | 1998-07-29 | 1999-07-29 | Therapeutische Verwendung als Histamin-H3-Rezeptor Liganden von Alkylaminen, die kein Imidazole enthalten |
| DE69920472T Expired - Lifetime DE69920472T2 (de) | 1998-07-29 | 1999-07-29 | Therapeutische verwendung als histamin-h3-rezeptor liganden von alkylaminen, die kein imidazole enthalten |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69920472T Expired - Lifetime DE69920472T2 (de) | 1998-07-29 | 1999-07-29 | Therapeutische verwendung als histamin-h3-rezeptor liganden von alkylaminen, die kein imidazole enthalten |
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| EP (4) | EP0982300A3 (https=) |
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| BE (1) | BE2016C048I2 (https=) |
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Families Citing this family (69)
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| EP0982300A3 (en) * | 1998-07-29 | 2000-03-08 | Societe Civile Bioprojet | Non-imidazole alkylamines as histamine H3 - receptor ligands and their therapeutic applications |
| US6620839B2 (en) | 2000-07-13 | 2003-09-16 | Abbott Laboratories | 1,3-disubstituted and 1,3,3-trisubstituted pyrrolidines as histamine-3 receptor ligands and their therapeutic applications |
| US6515013B2 (en) | 2000-07-13 | 2003-02-04 | Abbott Laboratories | 1,3-disubstituted and 1,3,3-trisubstituted pyrrolidines as histamine-3 receptor ligands and their therapeutic applications |
| ATE323076T1 (de) | 2000-08-08 | 2006-04-15 | Ortho Mcneil Pharm Inc | Bicyclische verbindungen als h3 rezeptor liganden |
| ATE354568T1 (de) | 2000-08-08 | 2007-03-15 | Ortho Mcneil Pharm Inc | Nicht-imidazol aryloxypiperidine als h3 rezeptor liganden |
| ES2260276T3 (es) * | 2000-08-08 | 2006-11-01 | Ortho-Mcneil Pharmaceutical, Inc. | Ariloxialquilaminas no imidazolicas como ligandos del receptor h3. |
| JP4564713B2 (ja) | 2000-11-01 | 2010-10-20 | ミレニアム・ファーマシューティカルズ・インコーポレイテッド | 窒素性複素環式化合物、ならびに窒素性複素環式化合物およびその中間体を作製するための方法 |
| US6316475B1 (en) | 2000-11-17 | 2001-11-13 | Abbott Laboratories | Aminoalkoxybiphenylcarboxamides as histamine-3 receptor ligands and their therapeutic applications |
| US6969730B2 (en) | 2001-03-16 | 2005-11-29 | Abbott Laboratories | Amines as histamine-3 receptor ligands and their therapeutic applications |
| EP1370546A2 (en) * | 2001-03-16 | 2003-12-17 | Abbott Laboratories | Novel amines as histamine-3 receptor ligands and their therapeutic applications |
| JP2004532834A (ja) * | 2001-03-23 | 2004-10-28 | イーライ・リリー・アンド・カンパニー | ヒスタミンh3受容体アンタゴニストである非イミダゾール系アリールアルキルアミン化合物、その製造および治療的使用 |
| US7064135B2 (en) | 2001-10-12 | 2006-06-20 | Novo Nordisk Inc. | Substituted piperidines |
| WO2003031432A1 (en) * | 2001-10-12 | 2003-04-17 | Novo Nordisk A/S | Substituted piperidines and their use for the treatment of diseases related to the histamine h3 receptor |
| CA2468159A1 (en) * | 2001-11-27 | 2003-06-05 | Merck & Co., Inc. | 4-aminoquinoline compounds |
| US7314937B2 (en) | 2002-03-21 | 2008-01-01 | Eli Lilly And Company | Non-imidazole aryl alkylamines compounds as histamine H3 receptor antagonists, preparation and therapeutic uses |
| AU2003256793A1 (en) * | 2002-08-20 | 2004-03-11 | Eli Lilly And Company | Substituted azepines as histamine h3 receptor antagonists, preparation and therapeutic uses |
| WO2004037800A1 (en) * | 2002-10-22 | 2004-05-06 | Glaxo Group Limited | Aryloxyalkylamine derivates as h3 receptor ligands |
| GB0224557D0 (en) * | 2002-10-22 | 2002-11-27 | Glaxo Group Ltd | Novel compounds |
| US7153889B2 (en) | 2002-11-12 | 2006-12-26 | Abbott Laboratories | Bicyclic-substituted amines as histamine-3 receptor ligands |
| AU2003291329A1 (en) * | 2002-11-12 | 2004-06-03 | Abbott Laboratories | Bicyclic-substituted amines as histamine-3 receptor ligands |
| GB0229820D0 (en) * | 2002-12-20 | 2003-01-29 | Glaxo Group Ltd | Novel compounds |
| KR100897642B1 (ko) * | 2002-12-20 | 2009-05-14 | 글락소 그룹 리미티드 | 신경 장애 치료용 벤즈아제핀 유도체 |
| WO2004078114A2 (en) * | 2003-02-28 | 2004-09-16 | Encysive Pharmaceuticals Inc. | Pyridine, pyrimidine, quinoline, quinazoline, and naphthalene urotensin-ii receptor antagonists. |
| EP1611902A4 (en) * | 2003-04-03 | 2006-04-12 | Kyowa Hakko Kogyo Kk | MEANS FOR THE PREVENTION AND / OR TREATMENT OF NEUROPATHIC PAIN |
| US7094790B2 (en) | 2003-05-07 | 2006-08-22 | Abbott Laboratories | Fused bicyclic-substituted amines as histamine-3 receptor ligands |
| FR2856596B1 (fr) * | 2003-06-27 | 2007-04-27 | Bioprojet Soc Civ | Nouvelle association medicamenteuse psychiatrique et utilisation d'une antagoniste ou agoniste inverse du recepteur h3 de l'histamine pour preparer un medicament prevenant des effets indesirables de psychotropes. |
| FR2874215B1 (fr) * | 2004-08-11 | 2006-09-29 | Sanofi Synthelabo | Derives de cyclopropylmethanones, leur preparation et leur utilisation en therapeutique |
| EP1720861A2 (en) | 2004-02-25 | 2006-11-15 | Eli Lilly And Company | Histamine h3 receptor antagonists, preparation and therapeutic uses |
| US7456164B2 (en) | 2004-05-07 | 2008-11-25 | Pfizer, Inc | 3- or 4-monosubtituted phenol and thiophenol derivatives useful as H3 ligands |
| US7145005B2 (en) | 2004-05-12 | 2006-12-05 | Abbott Laboratories | 2-(6-{2-[(2R)-2-Methyl-1-pyrrolidin-1-yl]-ethyl}-2-naphthalen-2-yl)-2H-pyridazin-3-one salts and their preparation |
| EP1595881A1 (en) | 2004-05-12 | 2005-11-16 | Pfizer Limited | Tetrahydronaphthyridine derivates useful as histamine H3 receptor ligands |
| US7205316B2 (en) | 2004-05-12 | 2007-04-17 | Abbott Laboratories | Tri- and bi-cyclic heteroaryl histamine-3 receptor ligands |
| US20050256309A1 (en) * | 2004-05-12 | 2005-11-17 | Altenbach Robert J | Tri-and bi-cyclic heteroaryl histamine-3 receptor ligands |
| US7098222B2 (en) | 2004-05-12 | 2006-08-29 | Abbott Laboratories | Bicyclic-substituted amines having cyclic-substituted monocyclic substituents |
| JP2008502644A (ja) * | 2004-06-18 | 2008-01-31 | グラクソ グループ リミテッド | ヒスタミンh3アンタゴニストとしての3−シクロアルキルベンズアゼピン |
| MX2007002136A (es) * | 2004-09-01 | 2007-04-02 | Pfizer Prod Inc | Antagonistas amino azabiciclicos del receptor 3 de la histamina. |
| US20060141072A1 (en) * | 2004-12-29 | 2006-06-29 | Arvanitidou Evangelia S | Oxidation resistant dentifrice compositions |
| DE602005005941D1 (de) * | 2005-02-10 | 2008-05-21 | Bioprojet Soc Civ | Monohydrochloridsalz von 1-Ä3-Ä3-(4-Chlorophenyl)propoxyÜpropylÜ-piperidin |
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| US2870151A (en) * | 1959-01-20 | Mqrpholine -ethers | ||
| DE184968C (https=) * | ||||
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| BE588558A (https=) * | 1959-03-13 | 1960-09-12 | ||
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-
1998
- 1998-12-31 EP EP98403351A patent/EP0982300A3/en not_active Withdrawn
-
1999
- 1999-07-29 CA CA2321881A patent/CA2321881C/en not_active Expired - Lifetime
- 1999-07-29 EP EP99941543A patent/EP1100503B1/en not_active Expired - Lifetime
- 1999-07-29 EP EP06002726A patent/EP2000462A3/en not_active Withdrawn
- 1999-07-29 PT PT04003944T patent/PT1428820E/pt unknown
- 1999-07-29 AU AU55119/99A patent/AU5511999A/en not_active Abandoned
- 1999-07-29 PT PT99941543T patent/PT1100503E/pt unknown
- 1999-07-29 ES ES99941543T patent/ES2226423T3/es not_active Expired - Lifetime
- 1999-07-29 DE DE69931409T patent/DE69931409T2/de not_active Expired - Lifetime
- 1999-07-29 DE DE69920472T patent/DE69920472T2/de not_active Expired - Lifetime
- 1999-07-29 JP JP2000562103A patent/JP4553487B2/ja not_active Expired - Lifetime
- 1999-07-29 ES ES04003944T patent/ES2260703T3/es not_active Expired - Lifetime
- 1999-07-29 US US09/622,199 patent/US7138413B1/en not_active Expired - Lifetime
- 1999-07-29 AT AT99941543T patent/ATE276751T1/de active
- 1999-07-29 AT AT04003944T patent/ATE326446T1/de active
- 1999-07-29 EP EP04003944A patent/EP1428820B1/en not_active Expired - Lifetime
- 1999-07-29 DK DK04003944T patent/DK1428820T3/da active
- 1999-07-29 WO PCT/EP1999/005744 patent/WO2000006254A2/en not_active Ceased
- 1999-07-29 DK DK99941543T patent/DK1100503T3/da active
-
2004
- 2004-06-01 US US10/856,838 patent/US7169928B2/en not_active Expired - Lifetime
-
2006
- 2006-07-03 US US11/478,682 patent/US7910605B2/en not_active Expired - Fee Related
-
2010
- 2010-06-02 JP JP2010127067A patent/JP5301501B2/ja not_active Expired - Lifetime
- 2010-12-15 US US12/968,807 patent/US20110281844A1/en not_active Abandoned
-
2016
- 2016-09-21 LU LU93229C patent/LU93229I2/fr unknown
- 2016-09-23 BE BE2016C048C patent/BE2016C048I2/fr unknown
- 2016-09-26 FR FR16C0038C patent/FR16C0038I2/fr active Active
- 2016-09-28 CY CY2016032C patent/CY2016032I2/el unknown
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