DE69915223T2 - Neue heterocyclische analoge von diphenylethylenverbindungen - Google Patents

Neue heterocyclische analoge von diphenylethylenverbindungen Download PDF

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Publication number
DE69915223T2
DE69915223T2 DE69915223T DE69915223T DE69915223T2 DE 69915223 T2 DE69915223 T2 DE 69915223T2 DE 69915223 T DE69915223 T DE 69915223T DE 69915223 T DE69915223 T DE 69915223T DE 69915223 T2 DE69915223 T2 DE 69915223T2
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DE
Germany
Prior art keywords
branched
radical
linear
atom
independently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69915223T
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German (de)
English (en)
Other versions
DE69915223D1 (de
Inventor
Partha Neogi
Bishwajit Nag
Satyanarayana Medicherla
Debendranath Dey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Theracos Inc
Original Assignee
Calyx Therapeutics Inc
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Filing date
Publication date
Priority claimed from US09/074,925 external-priority patent/US6245814B1/en
Application filed by Calyx Therapeutics Inc filed Critical Calyx Therapeutics Inc
Publication of DE69915223D1 publication Critical patent/DE69915223D1/de
Application granted granted Critical
Publication of DE69915223T2 publication Critical patent/DE69915223T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69915223T 1998-05-08 1999-05-07 Neue heterocyclische analoge von diphenylethylenverbindungen Expired - Lifetime DE69915223T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US74925 1998-05-08
US09/074,925 US6245814B1 (en) 1998-05-08 1998-05-08 Diphenylethylene compounds
US09/287,237 US6331633B1 (en) 1998-05-08 1999-04-06 Heterocyclic analogs of diphenylethylene compounds
US287237 1999-04-06
PCT/US1999/009982 WO1999058127A1 (en) 1998-05-08 1999-05-07 Novel heterocyclic analogs of diphenylethylene compounds

Publications (2)

Publication Number Publication Date
DE69915223D1 DE69915223D1 (de) 2004-04-08
DE69915223T2 true DE69915223T2 (de) 2005-01-27

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
DE69915223T Expired - Lifetime DE69915223T2 (de) 1998-05-08 1999-05-07 Neue heterocyclische analoge von diphenylethylenverbindungen

Country Status (13)

Country Link
US (1) US6331633B1 (https=)
EP (1) EP1007039B1 (https=)
JP (1) JP4577985B2 (https=)
KR (1) KR100595919B1 (https=)
CN (1) CN1151139C (https=)
AT (1) ATE260906T1 (https=)
AU (1) AU751235C (https=)
CA (1) CA2295599C (https=)
DE (1) DE69915223T2 (https=)
DK (1) DK1007039T3 (https=)
ES (1) ES2216513T3 (https=)
PT (1) PT1007039E (https=)
WO (1) WO1999058127A1 (https=)

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US20080103302A1 (en) * 2000-02-04 2008-05-01 Theracos, Inc. Compounds for treatment of inflammation, diabetes and related disorders
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US7781464B2 (en) * 2003-01-17 2010-08-24 Bexel Pharmaceuticals, Inc. Heterocyclic diphenyl ethers
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US7087576B2 (en) * 2003-10-07 2006-08-08 Bexel Pharmaceuticals, Inc. Dipeptide phenyl ethers
US20050171027A1 (en) 2003-12-29 2005-08-04 President And Fellows Of Harvard College Compositions for treating or preventing obesity and insulin resistance disorders
US8017634B2 (en) 2003-12-29 2011-09-13 President And Fellows Of Harvard College Compositions for treating obesity and insulin resistance disorders
JP2008528510A (ja) * 2005-01-20 2008-07-31 サートリス ファーマシューティカルズ， インコーポレイテッド 紅潮および／または薬物誘発性体重増加を処置するためのサーチュイン活性化化合物の使用
US20080267888A1 (en) * 2005-05-26 2008-10-30 Pandey Surendrakumar Satyanara Heterocyclic Derivatives
WO2006138418A2 (en) 2005-06-14 2006-12-28 President And Fellows Of Harvard College Improvement of cognitive performance with sirtuin activators
US20090131420A1 (en) * 2005-10-07 2009-05-21 Pandey Surendrakumar S Novel Heterocyclic Analogs of Biphenyl Ethers
KR101016875B1 (ko) * 2006-06-23 2011-02-22 현대중공업 주식회사 밀폐형 방청유 도포장치
CN112209896B (zh) * 2019-07-10 2023-05-16 苏州泽璟生物制药股份有限公司 噻唑烷二酮衍生物以及包含其的药物组合物
WO2022045836A1 (ko) * 2020-08-28 2022-03-03 (주)셀로스바이오텍 신규 티오히단토인 유도체 및 이의 용도

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Also Published As

Publication number Publication date
EP1007039B1 (en) 2004-03-03
AU3974199A (en) 1999-11-29
AU751235C (en) 2004-06-24
KR20010021615A (ko) 2001-03-15
EP1007039A4 (en) 2002-05-22
JP4577985B2 (ja) 2010-11-10
ATE260906T1 (de) 2004-03-15
PT1007039E (pt) 2004-07-30
CA2295599A1 (en) 1999-11-18
DE69915223D1 (de) 2004-04-08
KR100595919B1 (ko) 2006-07-03
CN1151139C (zh) 2004-05-26
US6331633B1 (en) 2001-12-18
ES2216513T3 (es) 2004-10-16
DK1007039T3 (da) 2004-07-12
HK1028348A1 (en) 2001-02-16
JP2002514598A (ja) 2002-05-21
WO1999058127A1 (en) 1999-11-18
EP1007039A1 (en) 2000-06-14
AU751235B2 (en) 2002-08-08
CA2295599C (en) 2009-01-20
CN1273528A (zh) 2000-11-15

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: THERACOS, INC., SUNNYVALE, CALIF., US

8328 Change in the person/name/address of the agent

Representative=s name: PATENTANWAELTE EFFERT, BRESSEL UND KOLLEGEN, 12489

8364 No opposition during term of opposition