KR100595919B1 - 디페닐에틸렌 화합물의 신규한 헤테로고리 유사체 - Google Patents

디페닐에틸렌 화합물의 신규한 헤테로고리 유사체 Download PDF

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Publication number
KR100595919B1
KR100595919B1 KR1020007000173A KR20007000173A KR100595919B1 KR 100595919 B1 KR100595919 B1 KR 100595919B1 KR 1020007000173 A KR1020007000173 A KR 1020007000173A KR 20007000173 A KR20007000173 A KR 20007000173A KR 100595919 B1 KR100595919 B1 KR 100595919B1
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Korean (ko)
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KR20010021615A (ko
Inventor
네오기파르타
나그비쉬와지트
메디첼라사리야나라이아나
데이데벤드라나쓰
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테라코스, 인코포레이티드
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Priority claimed from US09/074,925 external-priority patent/US6245814B1/en
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Publication of KR20010021615A publication Critical patent/KR20010021615A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
KR1020007000173A 1998-05-08 1999-05-07 디페닐에틸렌 화합물의 신규한 헤테로고리 유사체 Expired - Fee Related KR100595919B1 (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US09/074,925 1998-05-08
US9/074,925 1998-05-08
US09/074,925 US6245814B1 (en) 1998-05-08 1998-05-08 Diphenylethylene compounds
US09/287,237 1999-04-06
US09/287,237 US6331633B1 (en) 1998-05-08 1999-04-06 Heterocyclic analogs of diphenylethylene compounds
US9/287,237 1999-04-06
PCT/US1999/009982 WO1999058127A1 (en) 1998-05-08 1999-05-07 Novel heterocyclic analogs of diphenylethylene compounds

Publications (2)

Publication Number Publication Date
KR20010021615A KR20010021615A (ko) 2001-03-15
KR100595919B1 true KR100595919B1 (ko) 2006-07-03

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KR1020007000173A Expired - Fee Related KR100595919B1 (ko) 1998-05-08 1999-05-07 디페닐에틸렌 화합물의 신규한 헤테로고리 유사체

Country Status (13)

Country Link
US (1) US6331633B1 (https=)
EP (1) EP1007039B1 (https=)
JP (1) JP4577985B2 (https=)
KR (1) KR100595919B1 (https=)
CN (1) CN1151139C (https=)
AT (1) ATE260906T1 (https=)
AU (1) AU751235C (https=)
CA (1) CA2295599C (https=)
DE (1) DE69915223T2 (https=)
DK (1) DK1007039T3 (https=)
ES (1) ES2216513T3 (https=)
PT (1) PT1007039E (https=)
WO (1) WO1999058127A1 (https=)

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US7323496B2 (en) * 1999-11-08 2008-01-29 Theracos, Inc. Compounds for treatment of inflammation, diabetes and related disorders
US20080108825A1 (en) * 1999-11-08 2008-05-08 Theracos, Inc. Compounds for treatment of inflammation, diabetes and related disorders
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US20080103302A1 (en) * 2000-02-04 2008-05-01 Theracos, Inc. Compounds for treatment of inflammation, diabetes and related disorders
AU2002252227A1 (en) 2001-03-07 2002-09-24 Maxia Pharmaceuticals, Inc. Heterocyclic derivatives for the treatment of cancer and other proliferative diseases
JP2004523571A (ja) 2001-03-08 2004-08-05 マキシア・ファーマシューティカルズ・インコーポレイテッド Ｒｘｒ活性化分子
JP4425628B2 (ja) 2001-07-23 2010-03-03 ジョンソン・アンド・ジョンソン・コンシューマー・カンパニーズ・インコーポレイテッド 細胞保護化合物、薬学的処方物および美容用処方物、ならびに方法
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US7781464B2 (en) * 2003-01-17 2010-08-24 Bexel Pharmaceuticals, Inc. Heterocyclic diphenyl ethers
US6794401B2 (en) * 2003-01-17 2004-09-21 Bexel Pharmaceuticals, Inc. Amino acid phenoxy ethers
US7521465B2 (en) * 2003-01-17 2009-04-21 Bexel Pharmaceuticals, Inc. Diphenyl ether derivatives
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US7087576B2 (en) * 2003-10-07 2006-08-08 Bexel Pharmaceuticals, Inc. Dipeptide phenyl ethers
US20050171027A1 (en) 2003-12-29 2005-08-04 President And Fellows Of Harvard College Compositions for treating or preventing obesity and insulin resistance disorders
US8017634B2 (en) 2003-12-29 2011-09-13 President And Fellows Of Harvard College Compositions for treating obesity and insulin resistance disorders
JP2008528510A (ja) * 2005-01-20 2008-07-31 サートリス ファーマシューティカルズ， インコーポレイテッド 紅潮および／または薬物誘発性体重増加を処置するためのサーチュイン活性化化合物の使用
US20080267888A1 (en) * 2005-05-26 2008-10-30 Pandey Surendrakumar Satyanara Heterocyclic Derivatives
WO2006138418A2 (en) 2005-06-14 2006-12-28 President And Fellows Of Harvard College Improvement of cognitive performance with sirtuin activators
US20090131420A1 (en) * 2005-10-07 2009-05-21 Pandey Surendrakumar S Novel Heterocyclic Analogs of Biphenyl Ethers
KR101016875B1 (ko) * 2006-06-23 2011-02-22 현대중공업 주식회사 밀폐형 방청유 도포장치
CN112209896B (zh) * 2019-07-10 2023-05-16 苏州泽璟生物制药股份有限公司 噻唑烷二酮衍生物以及包含其的药物组合物
WO2022045836A1 (ko) * 2020-08-28 2022-03-03 (주)셀로스바이오텍 신규 티오히단토인 유도체 및 이의 용도

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Also Published As

Publication number Publication date
EP1007039B1 (en) 2004-03-03
AU3974199A (en) 1999-11-29
AU751235C (en) 2004-06-24
KR20010021615A (ko) 2001-03-15
EP1007039A4 (en) 2002-05-22
JP4577985B2 (ja) 2010-11-10
ATE260906T1 (de) 2004-03-15
PT1007039E (pt) 2004-07-30
CA2295599A1 (en) 1999-11-18
DE69915223D1 (de) 2004-04-08
CN1151139C (zh) 2004-05-26
US6331633B1 (en) 2001-12-18
ES2216513T3 (es) 2004-10-16
DK1007039T3 (da) 2004-07-12
HK1028348A1 (en) 2001-02-16
JP2002514598A (ja) 2002-05-21
WO1999058127A1 (en) 1999-11-18
EP1007039A1 (en) 2000-06-14
AU751235B2 (en) 2002-08-08
DE69915223T2 (de) 2005-01-27
CA2295599C (en) 2009-01-20
CN1273528A (zh) 2000-11-15

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