ES2216513T3 - Nuevos analogos heterociclicos de compuestos de difeniletileno. - Google Patents

Nuevos analogos heterociclicos de compuestos de difeniletileno.

Info

Publication number
ES2216513T3
ES2216513T3 ES99922836T ES99922836T ES2216513T3 ES 2216513 T3 ES2216513 T3 ES 2216513T3 ES 99922836 T ES99922836 T ES 99922836T ES 99922836 T ES99922836 T ES 99922836T ES 2216513 T3 ES2216513 T3 ES 2216513T3
Authority
ES
Spain
Prior art keywords
branched
compound
linear
alkyl
independently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99922836T
Other languages
English (en)
Spanish (es)
Inventor
Partha Neogi
Bishwajit Nag
Satyanarayana Medicherla
Debendranath Dey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Theracos Inc
Original Assignee
Theracos Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/074,925 external-priority patent/US6245814B1/en
Application filed by Theracos Inc filed Critical Theracos Inc
Application granted granted Critical
Publication of ES2216513T3 publication Critical patent/ES2216513T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
ES99922836T 1998-05-08 1999-05-07 Nuevos analogos heterociclicos de compuestos de difeniletileno. Expired - Lifetime ES2216513T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US74925 1998-05-08
US09/074,925 US6245814B1 (en) 1998-05-08 1998-05-08 Diphenylethylene compounds
US09/287,237 US6331633B1 (en) 1998-05-08 1999-04-06 Heterocyclic analogs of diphenylethylene compounds
US287237 1999-04-06

Publications (1)

Publication Number Publication Date
ES2216513T3 true ES2216513T3 (es) 2004-10-16

Family

ID=26756222

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99922836T Expired - Lifetime ES2216513T3 (es) 1998-05-08 1999-05-07 Nuevos analogos heterociclicos de compuestos de difeniletileno.

Country Status (13)

Country Link
US (1) US6331633B1 (https=)
EP (1) EP1007039B1 (https=)
JP (1) JP4577985B2 (https=)
KR (1) KR100595919B1 (https=)
CN (1) CN1151139C (https=)
AT (1) ATE260906T1 (https=)
AU (1) AU751235C (https=)
CA (1) CA2295599C (https=)
DE (1) DE69915223T2 (https=)
DK (1) DK1007039T3 (https=)
ES (1) ES2216513T3 (https=)
PT (1) PT1007039E (https=)
WO (1) WO1999058127A1 (https=)

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US7041941B2 (en) 1997-04-07 2006-05-09 Patented Medical Solutions, Llc Medical item thermal treatment systems and method of monitoring medical items for compliance with prescribed requirements
US7105552B2 (en) * 1998-05-08 2006-09-12 Theracos, Inc. Heterocyclic analogs of diphenylethylene compounds
US7407978B2 (en) * 1999-04-06 2008-08-05 Theracos, Inc. Heterocyclic analogs of diphenylethylene compounds
JP2003508391A (ja) 1999-08-31 2003-03-04 マキシア・ファーマシューティカルズ・インコーポレイテッド ベンジリデン−チアゾリジンジオン類およびアナログ類ならびに糖尿病の治療におけるその使用
US7323496B2 (en) * 1999-11-08 2008-01-29 Theracos, Inc. Compounds for treatment of inflammation, diabetes and related disorders
US20080108825A1 (en) * 1999-11-08 2008-05-08 Theracos, Inc. Compounds for treatment of inflammation, diabetes and related disorders
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US20080103302A1 (en) * 2000-02-04 2008-05-01 Theracos, Inc. Compounds for treatment of inflammation, diabetes and related disorders
AU2002252227A1 (en) 2001-03-07 2002-09-24 Maxia Pharmaceuticals, Inc. Heterocyclic derivatives for the treatment of cancer and other proliferative diseases
JP2004523571A (ja) 2001-03-08 2004-08-05 マキシア・ファーマシューティカルズ・インコーポレイテッド Ｒｘｒ活性化分子
JP4425628B2 (ja) 2001-07-23 2010-03-03 ジョンソン・アンド・ジョンソン・コンシューマー・カンパニーズ・インコーポレイテッド 細胞保護化合物、薬学的処方物および美容用処方物、ならびに方法
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US7102000B2 (en) 2002-03-08 2006-09-05 Incyte San Diego Inc. Heterocyclic amide derivatives for the treatment of diabetes and other diseases
US7196108B2 (en) 2002-03-08 2007-03-27 Incyte San Diego Inc. Bicyclic heterocycles for the treatment of diabetes and other diseases
US7977049B2 (en) 2002-08-09 2011-07-12 President And Fellows Of Harvard College Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms
US7041693B2 (en) 2002-10-04 2006-05-09 Bristol-Myers Squibb Company Hydantoin derivatives as inhibitors of matrix metalloproteinases and/or TNF-α converting enzyme (TACE)
US7781464B2 (en) * 2003-01-17 2010-08-24 Bexel Pharmaceuticals, Inc. Heterocyclic diphenyl ethers
US6794401B2 (en) * 2003-01-17 2004-09-21 Bexel Pharmaceuticals, Inc. Amino acid phenoxy ethers
US7521465B2 (en) * 2003-01-17 2009-04-21 Bexel Pharmaceuticals, Inc. Diphenyl ether derivatives
JP2007530417A (ja) 2003-07-01 2007-11-01 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 細胞及び生物の寿命及びストレス応答を操作するための組成物
US7087576B2 (en) * 2003-10-07 2006-08-08 Bexel Pharmaceuticals, Inc. Dipeptide phenyl ethers
US20050171027A1 (en) 2003-12-29 2005-08-04 President And Fellows Of Harvard College Compositions for treating or preventing obesity and insulin resistance disorders
US8017634B2 (en) 2003-12-29 2011-09-13 President And Fellows Of Harvard College Compositions for treating obesity and insulin resistance disorders
JP2008528510A (ja) * 2005-01-20 2008-07-31 サートリス ファーマシューティカルズ， インコーポレイテッド 紅潮および／または薬物誘発性体重増加を処置するためのサーチュイン活性化化合物の使用
US20080267888A1 (en) * 2005-05-26 2008-10-30 Pandey Surendrakumar Satyanara Heterocyclic Derivatives
WO2006138418A2 (en) 2005-06-14 2006-12-28 President And Fellows Of Harvard College Improvement of cognitive performance with sirtuin activators
US20090131420A1 (en) * 2005-10-07 2009-05-21 Pandey Surendrakumar S Novel Heterocyclic Analogs of Biphenyl Ethers
KR101016875B1 (ko) * 2006-06-23 2011-02-22 현대중공업 주식회사 밀폐형 방청유 도포장치
CN112209896B (zh) * 2019-07-10 2023-05-16 苏州泽璟生物制药股份有限公司 噻唑烷二酮衍生物以及包含其的药物组合物
WO2022045836A1 (ko) * 2020-08-28 2022-03-03 (주)셀로스바이오텍 신규 티오히단토인 유도체 및 이의 용도

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Also Published As

Publication number Publication date
EP1007039B1 (en) 2004-03-03
AU3974199A (en) 1999-11-29
AU751235C (en) 2004-06-24
KR20010021615A (ko) 2001-03-15
EP1007039A4 (en) 2002-05-22
JP4577985B2 (ja) 2010-11-10
ATE260906T1 (de) 2004-03-15
PT1007039E (pt) 2004-07-30
CA2295599A1 (en) 1999-11-18
DE69915223D1 (de) 2004-04-08
KR100595919B1 (ko) 2006-07-03
CN1151139C (zh) 2004-05-26
US6331633B1 (en) 2001-12-18
DK1007039T3 (da) 2004-07-12
HK1028348A1 (en) 2001-02-16
JP2002514598A (ja) 2002-05-21
WO1999058127A1 (en) 1999-11-18
EP1007039A1 (en) 2000-06-14
AU751235B2 (en) 2002-08-08
DE69915223T2 (de) 2005-01-27
CA2295599C (en) 2009-01-20
CN1273528A (zh) 2000-11-15

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