DE69840166D1 - Magnetisch unterstützter bindungstest unter verwendung eines auf magnetismus reagierendes reagenzes - Google Patents

Magnetisch unterstützter bindungstest unter verwendung eines auf magnetismus reagierendes reagenzes

Info

Publication number
DE69840166D1
DE69840166D1 DE69840166T DE69840166T DE69840166D1 DE 69840166 D1 DE69840166 D1 DE 69840166D1 DE 69840166 T DE69840166 T DE 69840166T DE 69840166 T DE69840166 T DE 69840166T DE 69840166 D1 DE69840166 D1 DE 69840166D1
Authority
DE
Germany
Prior art keywords
reagent
magnetic field
magnetism
reaction mixture
binding test
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69840166T
Other languages
English (en)
Inventor
Thomas E Rohr
Tuan A Elstrom
Lawrence V Howard
Eric B Shain
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE69840166D1 publication Critical patent/DE69840166D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • G01N33/54333Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/806Electrical property or magnetic property
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/70Nanostructure
    • Y10S977/773Nanoparticle, i.e. structure having three dimensions of 100 nm or less
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/70Nanostructure
    • Y10S977/832Nanostructure having specified property, e.g. lattice-constant, thermal expansion coefficient
    • Y10S977/838Magnetic property of nanomaterial
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/84Manufacture, treatment, or detection of nanostructure
    • Y10S977/89Deposition of materials, e.g. coating, cvd, or ald
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/92Detection of biochemical
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/932Specified use of nanostructure for electronic or optoelectronic application
    • Y10S977/953Detector using nanostructure
    • Y10S977/96Of magnetic property

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Sampling And Sample Adjustment (AREA)
DE69840166T 1997-05-16 1998-05-15 Magnetisch unterstützter bindungstest unter verwendung eines auf magnetismus reagierendes reagenzes Expired - Lifetime DE69840166D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/857,440 US5998224A (en) 1997-05-16 1997-05-16 Magnetically assisted binding assays utilizing a magnetically responsive reagent
PCT/US1998/009945 WO1998052043A1 (en) 1997-05-16 1998-05-15 Magnetically assisted binding assays utilizing a magnetically responsive reagent

Publications (1)

Publication Number Publication Date
DE69840166D1 true DE69840166D1 (de) 2008-12-11

Family

ID=25326006

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69840166T Expired - Lifetime DE69840166D1 (de) 1997-05-16 1998-05-15 Magnetisch unterstützter bindungstest unter verwendung eines auf magnetismus reagierendes reagenzes

Country Status (8)

Country Link
US (1) US5998224A (de)
EP (2) EP0981749B1 (de)
JP (4) JP4237267B2 (de)
AT (1) ATE412898T1 (de)
CA (1) CA2290018C (de)
DE (1) DE69840166D1 (de)
ES (2) ES2316163T3 (de)
WO (1) WO1998052043A1 (de)

Families Citing this family (122)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7885697B2 (en) 2004-07-13 2011-02-08 Dexcom, Inc. Transcutaneous analyte sensor
DE19753851A1 (de) * 1997-12-04 1999-06-10 Roche Diagnostics Gmbh Vorrichtung zum kapillaren Flüssigkeitstransport
AU3474100A (en) * 1999-01-25 2000-08-07 Minerva Biotechnologies Corporation Rapid and sensitive detection of aberrant protein aggregation in neurodegenerative diseases
EP1198712A2 (de) * 1999-02-17 2002-04-24 Kilian Hennes Verfahren zum darstellen von biologisch aktivierten induktivitätsändernden partikeln sowie vorrichtung dafür
WO2001018235A2 (en) * 1999-09-09 2001-03-15 Eichrom Technologies, Inc. Lateral flow device with metal oxide indicator and assay method employing same
US7537938B2 (en) 2000-04-28 2009-05-26 Monogram Biosciences, Inc. Biomarker detection in circulating cells
US7811768B2 (en) * 2001-01-26 2010-10-12 Aviva Biosciences Corporation Microdevice containing photorecognizable coding patterns and methods of using and producing the same
US7015047B2 (en) * 2001-01-26 2006-03-21 Aviva Biosciences Corporation Microdevices having a preferential axis of magnetization and uses thereof
FR2826882B1 (fr) * 2001-07-09 2003-09-12 Bio Merieux Procede de traitement de particules magnetiques et configurations d'aimants permettant la mise en oeuvre de ce procede
US7169577B2 (en) * 2001-07-27 2007-01-30 Surface Logix, Inc. Cell isolation and screening device and method of using same
US7169578B2 (en) * 2001-07-27 2007-01-30 Surface Logix, Inc. Cell isolation and screening device and method of using same
US7285412B2 (en) * 2001-07-27 2007-10-23 Surface Logix Inc. Device for magnetic immobilization of cells
AU2003215388A1 (en) * 2002-02-22 2003-09-09 Purdue Research Foundation Magnetic nanomaterials and methods for detection of biological materials
US8697029B2 (en) * 2002-04-18 2014-04-15 The Regents Of The University Of Michigan Modulated physical and chemical sensors
CA2491093A1 (en) * 2002-06-28 2004-01-08 Purdue Research Foundation Magnetic nanomaterials and methods for detection of biological materials
US7601491B2 (en) 2003-02-06 2009-10-13 Becton, Dickinson And Company Pretreatment method for extraction of nucleic acid from biological samples and kits therefor
CN1280428C (zh) * 2003-05-19 2006-10-18 清华大学 一种基于微小颗粒的生物芯片系统及其应用
FR2855613B1 (fr) * 2003-05-26 2005-08-19 Biocytex Procede de detection et de quantification multiplex d'analytes dans un echantillon a l'aide de microspheres
US7402398B2 (en) 2003-07-17 2008-07-22 Monogram Biosciences, Inc. Measuring receptor homodimerization
CA2535510C (en) 2003-08-11 2013-10-15 Monogram Biosciences, Inc. Detecting and profiling molecular complexes
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US20050282182A1 (en) * 2003-12-30 2005-12-22 Universal Bio Research Co., Ltd. Reaction vessel and reaction apparatus comprising three-dimensional particle array
JP2005315677A (ja) * 2004-04-28 2005-11-10 Canon Inc 検出装置および検出方法
DE102004033811A1 (de) * 2004-07-12 2006-02-02 Salama, Abdulgabar, Prof. Dr. Verfahren zum einfachen und schnellen Nachweis von Zellen und Biomolekülen mit Hilfe paramagnetischer Partikel
US20070045902A1 (en) 2004-07-13 2007-03-01 Brauker James H Analyte sensor
US20060024776A1 (en) * 2004-08-02 2006-02-02 Mcmillian Ray Magnetic particle capture of whole intact organisms from clinical samples
CA2587085C (en) 2004-10-27 2017-08-08 Cepheid Closed-system multi-stage nucleic acid amplification reactions
US7939267B2 (en) * 2004-11-04 2011-05-10 Laboratory Corporation Of America Holdings Detection of activation of endothelial cells as surrogate marker for angiogenesis
WO2006081558A2 (en) 2005-01-28 2006-08-03 Duke University Apparatuses and methods for manipulating droplets on a printed circuit board
DE602006000724T2 (de) 2005-02-05 2009-04-23 Samsung Electronics Co., Ltd., Suwon Sensorschalter und seine Verwendung in einem Nachweisverfahren
US7781228B2 (en) 2005-04-07 2010-08-24 Menon & Associates, Inc. Magnetic resonance system and method to detect and confirm analytes
US7300631B2 (en) 2005-05-02 2007-11-27 Bioscale, Inc. Method and apparatus for detection of analyte using a flexural plate wave device and magnetic particles
US7263874B2 (en) * 2005-06-08 2007-09-04 Bioscale, Inc. Methods and apparatus for determining properties of a fluid
US20060281104A1 (en) * 2005-06-13 2006-12-14 Macevicz Stephen C Leuco dye particles and uses thereof
US20070020699A1 (en) * 2005-07-19 2007-01-25 Idexx Laboratories, Inc. Lateral flow assay and device using magnetic particles
US20070059782A1 (en) * 2005-09-13 2007-03-15 Graham Henry A Magnetic particle tagged blood bank reagents and techniques
US9488665B2 (en) * 2005-09-13 2016-11-08 Chrome Red Technologies, Llc Magnetic particle tagged reagents and techniques
US20070166730A1 (en) 2006-01-19 2007-07-19 Menon & Associates, Inc. Magnetic resonance system and method to detect and confirm analytes
US20100239864A1 (en) * 2006-03-27 2010-09-23 Tokyo Institute Of Technology Method of manufacturing polymer coated ferromagnetic particles and polymer coated ferromagnetic particles
US9476856B2 (en) * 2006-04-13 2016-10-25 Advanced Liquid Logic, Inc. Droplet-based affinity assays
US8492168B2 (en) * 2006-04-18 2013-07-23 Advanced Liquid Logic Inc. Droplet-based affinity assays
US20140193807A1 (en) 2006-04-18 2014-07-10 Advanced Liquid Logic, Inc. Bead manipulation techniques
US8637324B2 (en) 2006-04-18 2014-01-28 Advanced Liquid Logic, Inc. Bead incubation and washing on a droplet actuator
US7901947B2 (en) 2006-04-18 2011-03-08 Advanced Liquid Logic, Inc. Droplet-based particle sorting
US7851184B2 (en) * 2006-04-18 2010-12-14 Advanced Liquid Logic, Inc. Droplet-based nucleic acid amplification method and apparatus
US7439014B2 (en) 2006-04-18 2008-10-21 Advanced Liquid Logic, Inc. Droplet-based surface modification and washing
US8809068B2 (en) 2006-04-18 2014-08-19 Advanced Liquid Logic, Inc. Manipulation of beads in droplets and methods for manipulating droplets
US10078078B2 (en) 2006-04-18 2018-09-18 Advanced Liquid Logic, Inc. Bead incubation and washing on a droplet actuator
US8900828B2 (en) 2006-05-01 2014-12-02 Cepheid Methods and apparatus for sequential amplification reactions
US9675972B2 (en) 2006-05-09 2017-06-13 Advanced Liquid Logic, Inc. Method of concentrating beads in a droplet
US8119352B2 (en) * 2006-06-20 2012-02-21 Cepheld Multi-stage amplification reactions by control of sequence replication times
WO2008014223A2 (en) * 2006-07-24 2008-01-31 Becton, Dickinson And Company Assay particle concentration and imaging apparatus and method
KR101431778B1 (ko) 2007-02-09 2014-08-20 어드밴스드 리퀴드 로직, 아이엔씨. 자성 비즈를 이용하는 액적 작동기 장치 및 방법
US9068977B2 (en) * 2007-03-09 2015-06-30 The Regents Of The University Of Michigan Non-linear rotation rates of remotely driven particles and uses thereof
WO2009032863A2 (en) 2007-09-04 2009-03-12 Advanced Liquid Logic, Inc. Droplet actuator with improved top substrate
CN103707643B (zh) 2007-12-23 2016-06-01 先进液体逻辑公司 液滴致动器配置以及引导液滴操作的方法
US7927561B2 (en) * 2008-01-10 2011-04-19 Becton, Dickinson And Company Rapid particle detection assay
WO2009091926A2 (en) 2008-01-17 2009-07-23 The Regents Of The University Of California Integrated magnetic field generation and detection platform
US8076162B2 (en) * 2008-04-07 2011-12-13 Life Bioscience, Inc. Method of providing particles having biological-binding areas for biological applications
US8852952B2 (en) 2008-05-03 2014-10-07 Advanced Liquid Logic, Inc. Method of loading a droplet actuator
US8926065B2 (en) 2009-08-14 2015-01-06 Advanced Liquid Logic, Inc. Droplet actuator devices and methods
WO2011057197A2 (en) 2009-11-06 2011-05-12 Advanced Liquid Logic, Inc. Integrated droplet actuator for gel electrophoresis and molecular analysis
EP2516669B1 (de) 2009-12-21 2016-10-12 Advanced Liquid Logic, Inc. Enzymassays auf einem tropfenaktuator
WO2011100358A2 (en) * 2010-02-09 2011-08-18 Fabrico Technology, Inc. Systems and methods for detecting target analytes
US11402375B2 (en) 2010-08-05 2022-08-02 Abbott Point Of Care Inc. Magnetic immunosensor with trench configuration and method of use
EP2600973B1 (de) 2010-08-05 2016-05-25 Abbott Point Of Care, Inc. Immuntestverfahren und gerät mittels magnetisches bead-basierter affinitätssäule
WO2012019107A1 (en) 2010-08-05 2012-02-09 Abbott Point Of Care Inc. Magnetic immunosensor and method of use
US9329175B2 (en) 2010-08-05 2016-05-03 Abbott Point Of Care Inc. Oscillating immunoassay method and device
WO2012027747A2 (en) 2010-08-27 2012-03-01 The Regents Of The University Of Michigan Asynchronous magnetic bead rotation sensing systems and methods
US20120077184A1 (en) * 2010-09-28 2012-03-29 Starkdx Incorporated Electromagnetic multiplex assay biosensor
WO2012142179A2 (en) 2011-04-11 2012-10-18 The Regents Of The University Of Michigan Magnetically induced microspinning for super-detection and super-characterization of biomarkers and live cells
CA2833897C (en) 2011-05-09 2020-05-19 Advanced Liquid Logic, Inc. Microfluidic feedback using impedance detection
CN103733059B (zh) 2011-07-06 2016-04-06 先进流体逻辑公司 在微滴执行机构上的试剂储存
US9513253B2 (en) 2011-07-11 2016-12-06 Advanced Liquid Logic, Inc. Droplet actuators and techniques for droplet-based enzymatic assays
US9446404B2 (en) 2011-07-25 2016-09-20 Advanced Liquid Logic, Inc. Droplet actuator apparatus and system
JP2013088164A (ja) * 2011-10-14 2013-05-13 Hitachi High-Technologies Corp 自動分析装置
WO2013078216A1 (en) 2011-11-21 2013-05-30 Advanced Liquid Logic Inc Glucose-6-phosphate dehydrogenase assays
US9797817B2 (en) 2012-05-03 2017-10-24 The Regents Of The University Of Michigan Multi-mode separation for target detection
EP2664914A1 (de) * 2012-05-16 2013-11-20 Koninklijke Philips N.V. Magnetisch unterstützte Verarbeitung eines Mediums
IN2015DN00359A (de) 2012-06-27 2015-06-12 Advanced Liquid Logic Inc
CN104487845B (zh) * 2012-07-06 2017-06-20 凸版印刷株式会社 被检物质的检测系统
JP6120518B2 (ja) 2012-10-10 2017-04-26 公益財団法人かずさDna研究所 簡易測定器具
WO2014144782A2 (en) 2013-03-15 2014-09-18 Ancera, Inc. Systems and methods for active particle separation
WO2014145765A1 (en) 2013-03-15 2014-09-18 Ancera, Inc. Systems and methods for bead-based assays in ferrofluids
JP6420055B2 (ja) * 2013-03-29 2018-11-07 積水メディカル株式会社 イムノクロマト用着色粒子及びこれを用いた診断用イムノクロマト試薬
US9983110B2 (en) 2013-11-04 2018-05-29 The Regents Of The University Of Michigan Asynchronous magnetic bead rotation (AMBR) microviscometer for analysis of analytes
EP3249055B1 (de) * 2013-12-12 2019-06-26 Altratech Limited Nukleinsäureanalyseverfahren und -vorrichtung
US10533170B2 (en) * 2014-03-14 2020-01-14 Shimadzu Corporation Method for manipulating magnetic particles and device for manipulating magnetic particles
EP3140838B1 (de) 2014-05-05 2021-08-25 3D Glass Solutions, Inc. Induktives gerät in einer fotodefinierbaren glasstruktur
CN106457196B (zh) * 2014-05-23 2019-04-26 株式会社岛津制作所 磁性物质颗粒的操作方法和磁性物质颗粒操作用装置
WO2016013115A1 (ja) * 2014-07-25 2016-01-28 株式会社 リージャー 希釈生体試料成分の分析方法
KR101860543B1 (ko) * 2015-01-09 2018-05-24 한양대학교 에리카산학협력단 성호르몬 검출용 시약 키트 및 이를 이용한 성호르몬 검출 방법
JP6865466B2 (ja) * 2015-06-26 2021-04-28 株式会社カワノラボ 分散質分析方法、および分析装置
US11285490B2 (en) 2015-06-26 2022-03-29 Ancera, Llc Background defocusing and clearing in ferrofluid-based capture assays
US20180178261A1 (en) * 2015-09-22 2018-06-28 Halliburton Energy Services, Inc Optical Device Window Cleaning System
US10070533B2 (en) 2015-09-30 2018-09-04 3D Glass Solutions, Inc. Photo-definable glass with integrated electronics and ground plane
AU2017223993B2 (en) 2016-02-25 2019-07-04 3D Glass Solutions, Inc. 3D capacitor and capacitor array fabricating photoactive substrates
US11161773B2 (en) 2016-04-08 2021-11-02 3D Glass Solutions, Inc. Methods of fabricating photosensitive substrates suitable for optical coupler
KR101994370B1 (ko) * 2016-08-24 2019-06-28 주식회사 제놉시 항체 및 자성 나노 입자가 결합된 전도성 고분자를 포함하는 혈중 암세포 검출 및 회수용 자성 나노 구조체
WO2018075913A1 (en) 2016-10-20 2018-04-26 Quantum Diamond Technologies Inc. Methods and apparatus for magnetic particle analysis using wide-field diamond magnetic imaging
US10590409B2 (en) * 2016-12-06 2020-03-17 Wisconsin Alumni Research Foundation Method and device for disaggregation via heterogeneous particles
US11513115B2 (en) 2016-12-23 2022-11-29 Quantum Diamond Technologies Inc. Methods and apparatus for magnetic multi-bead assays
KR102420212B1 (ko) 2017-04-28 2022-07-13 3디 글래스 솔루션즈 인코포레이티드 Rf 서큘레이터
AU2018297035B2 (en) 2017-07-07 2021-02-25 3D Glass Solutions, Inc. 2D and 3D RF lumped element devices for RF system in a package photoactive glass substrates
WO2019027917A1 (en) 2017-07-31 2019-02-07 Quantum Diamond Technologies, Inc METHODS AND APPARATUS FOR SAMPLE MEASUREMENT
KR102614826B1 (ko) 2017-12-15 2023-12-19 3디 글래스 솔루션즈 인코포레이티드 결합 전송 라인 공진 rf 필터
JP7226832B2 (ja) 2018-01-04 2023-02-21 スリーディー グラス ソリューションズ,インク 高効率rf回路のためのインピーダンス整合伝導構造
WO2019181803A1 (ja) * 2018-03-20 2019-09-26 住友電気工業株式会社 微小粒子計測装置
WO2019199470A1 (en) 2018-04-10 2019-10-17 3D Glass Solutions, Inc. Rf integrated power condition capacitor
KR102475010B1 (ko) 2018-05-29 2022-12-07 3디 글래스 솔루션즈 인코포레이티드 저 삽입 손실 rf 전송 라인
JP7320845B2 (ja) * 2018-06-08 2023-08-04 国立研究開発法人産業技術総合研究所 標的物質検出方法及び標的物質検出キット
US11139582B2 (en) 2018-09-17 2021-10-05 3D Glass Solutions, Inc. High efficiency compact slotted antenna with a ground plane
WO2020139951A1 (en) 2018-12-28 2020-07-02 3D Glass Solutions, Inc. Heterogenous integration for rf, microwave and mm wave systems in photoactive glass substrates
US11270843B2 (en) 2018-12-28 2022-03-08 3D Glass Solutions, Inc. Annular capacitor RF, microwave and MM wave systems
KR20210147040A (ko) 2019-04-05 2021-12-06 3디 글래스 솔루션즈 인코포레이티드 유리 기반의 빈 기판 집적 도파관 디바이스
WO2020214788A1 (en) 2019-04-18 2020-10-22 3D Glass Solutions, Inc. High efficiency die dicing and release
WO2020225900A1 (ja) * 2019-05-09 2020-11-12 三菱電機株式会社 磁性摩耗粉量測定装置及び機械装置
KR20220164800A (ko) 2020-04-17 2022-12-13 3디 글래스 솔루션즈 인코포레이티드 광대역 인덕터
CN115485555A (zh) * 2020-05-12 2022-12-16 新加坡国立大学 一种用于病毒和生物标志物检测的方法
RU200521U1 (ru) * 2020-05-26 2020-10-28 Алексей Николаевич Темников Портативный сканер-дисплей магнитного поля
EP4252907A1 (de) * 2022-03-30 2023-10-04 Blink AG Verfahren zur anordnung von mikrokugeln in einer nichtwässrigen flüssigen phase

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985649A (en) * 1974-11-25 1976-10-12 Eddelman Roy T Ferromagnetic separation process and material
US4070246A (en) * 1976-04-09 1978-01-24 Abbott Laboratories Reactive matrices
GB8401368D0 (en) * 1984-01-19 1984-02-22 Amersham Int Plc Assay method
US5076950A (en) * 1985-12-20 1991-12-31 Syntex (U.S.A.) Inc. Magnetic composition for particle separation
JPH0614051B2 (ja) * 1986-02-10 1994-02-23 株式会社ニッテク 抗原―抗体不溶化担体の選別方法
US4960691A (en) * 1986-09-29 1990-10-02 Abbott Laboratories Chromatographic test strip for determining ligands or receptors
JPS63108264A (ja) * 1986-10-25 1988-05-13 Nippon Telegr & Teleph Corp <Ntt> 磁気免疫測定方法および該方法を実施するために使用する検査試薬片
US5236824A (en) * 1988-04-26 1993-08-17 Nippon Telegraph And Telephone Corporation Laser magnetic immunoassay method and method by a magnetophoresis apparatus therefor
JP2599175B2 (ja) * 1988-04-26 1997-04-09 日本電信電話株式会社 レーザ磁気免疫測定方法及び測定装置並びにレーザ磁気免疫測定に用いる超常磁性体標識体及びその製造方法
US5145784A (en) * 1988-05-04 1992-09-08 Cambridge Biotech Corporation Double capture assay method employing a capillary flow device
US5108933A (en) * 1988-09-16 1992-04-28 Immunicon Corporation Manipulation of colloids for facilitating magnetic separations
US5252459A (en) * 1988-09-23 1993-10-12 Abbott Laboratories Indicator reagents, diagnostic assays and test kits employing organic polymer latex particles
CA1335181C (en) * 1988-10-11 1995-04-11 R. Alan Hardwick System for selective cell separation from cell concentrate
TW221493B (de) * 1990-07-10 1994-03-01 Cardiovascular Diagnostics Inc
JPH0552849A (ja) * 1991-08-28 1993-03-02 Terumo Corp 検体の特異的検出および特異的分離方法
US5445970A (en) * 1992-03-20 1995-08-29 Abbott Laboratories Magnetically assisted binding assays using magnetically labeled binding members
US5445971A (en) * 1992-03-20 1995-08-29 Abbott Laboratories Magnetically assisted binding assays using magnetically labeled binding members
DE69333569T2 (de) * 1992-03-20 2005-08-04 Abbott Laboratories, Abbott Park Magnetisch assistierte bindungsassays unter verwendung von magnetisch markierten bindungspartnern.
JP2625578B2 (ja) * 1992-03-20 1997-07-02 アボツト・ラボラトリーズ 磁気標識した結合要素を用いた結合親和力の測定方法
WO1993022058A1 (en) * 1992-05-01 1993-11-11 Trustees Of The University Of Pennsylvania Polynucleotide amplification analysis using a microfabricated device
US5322756A (en) * 1992-07-09 1994-06-21 Xerox Corporation Magnetic fluids and method of preparation
US5358659A (en) * 1992-07-09 1994-10-25 Xerox Corporation Magnetic materials with single-domain and multidomain crystallites and a method of preparation
WO1994020855A1 (en) * 1993-03-04 1994-09-15 Sapidyne, Inc. Assay flow apparatus and method
US5374531A (en) * 1993-03-22 1994-12-20 Zynaxis, Inc. Immunoassay for determination of cells
FR2708348B1 (fr) * 1993-07-28 1995-10-06 Stago Diagnostica Procédé de dosage d'une substance immunologique au moyen de particules de latex magnétiques et de particules non-magnétiques.
GB9409333D0 (en) * 1994-05-10 1994-06-29 Palmer Richard F Analytical method and device for use therein
US5656429A (en) * 1994-10-03 1997-08-12 Adelman; Lonnie W. Polynucleotide and protein analysis method using magnetizable moieties
FR2732116B1 (fr) * 1995-03-21 1997-05-09 Bio Merieux Procede et dispositif pour la determination qualitative et/ou quantitative d'un analyte, notamment d'une bacterie, dans un echantillon, par voie magnetique
JPH08304399A (ja) * 1995-04-28 1996-11-22 Mitsubishi Chem Corp 磁性体粒子の分離方法およびそれを用いた免疫分析方法

Also Published As

Publication number Publication date
EP1881325A1 (de) 2008-01-23
EP0981749A1 (de) 2000-03-01
JP4806457B2 (ja) 2011-11-02
EP0981749B1 (de) 2008-10-29
JP4324212B2 (ja) 2009-09-02
CA2290018A1 (en) 1998-11-19
EP1881325B1 (de) 2012-01-11
CA2290018C (en) 2011-07-19
JP2008003083A (ja) 2008-01-10
US5998224A (en) 1999-12-07
ATE412898T1 (de) 2008-11-15
JP2011257413A (ja) 2011-12-22
JP2009204617A (ja) 2009-09-10
JP2002504993A (ja) 2002-02-12
JP4237267B2 (ja) 2009-03-11
ES2378782T3 (es) 2012-04-17
WO1998052043A1 (en) 1998-11-19
ES2316163T3 (es) 2009-04-01

Similar Documents

Publication Publication Date Title
DE69840166D1 (de) Magnetisch unterstützter bindungstest unter verwendung eines auf magnetismus reagierendes reagenzes
TW356519B (en) A device for highest sensitivity magnetic detection of analytes
ES2079434T3 (es) Ensayos de ligandos-receptores que utilizan un umbral.
BG104275A (en) Method and device for express analysis of tested parameters in biological samples
ATE467835T1 (de) Membran-basierendes verfahren unter verwendung von zeitaufgelösten fluoreszenzmessungen
DK0878713T3 (da) Fremgangsmåde og apparat til korrektion af omgivelsestemperaturindflydelse i biosensorer
DK0877252T3 (da) Fremgangsmåde og apparat til luminescensassays
EP0417305A4 (en) Analyzer of liquid sample and analyzing method of liquid sample using said analyzer
DK1111386T3 (da) Teststrimmel til bestemmelse af en analyt i en flydende pröve
ATE448479T1 (de) Analyse von biologischen und/oder chemischen gemischen unter verwendung von magnetischen teilchen
DK0779367T3 (da) Analyseindretning med stabilt koblingsfarvestof til fotometrisk bestemmelse af analytter
GB2323442A (en) Methods for applying a reagent to an analytical test device
DE69809752D1 (de) Vorrichtung zum testen der analytkonzentration in einer flüssigkeit
KR880014370A (ko) 고체 상(相) 분석 방법
DK0728309T3 (da) Analyseindretninger og fremstilling heraf
EP0469377A3 (en) Analysis system and method for the determination of an analyte in a liquid sample
DK406087D0 (da) Fremgangsmaade og testkit til bestemmelse af koncentrationen af en i en biologisk vaeske vaerende aktiv forbindelse
JPS57103055A (en) Analysis of homogeneous peculiar bond and apparatus used therefor
NO20003709L (no) Fremgangsmate for detektering av en analytt, og omsluttingsmiddel og kit for anvendelse deri
NO850527L (no) Forsoeksanordning for bestemmelse av ioner i vandige proever
DK476489D0 (da) Fremgangsmaade til bestemmelse af en maengde antigen og antistof
ATE287084T1 (de) Immunoassay verfahren und testsatz
DE69533586D1 (de) Verfahren zum testen eines asialoglycoproteinrezeptors und testreagenz dafür
DK563588A (da) Proevningsapparat til brug ved proevning for en analysand
DK0490232T3 (da) Apparat til påvisning af markerede mineralolier

Legal Events

Date Code Title Description
8364 No opposition during term of opposition