ATE412898T1 - Magnetisch unterstützter bindungstest unter verwendung eines auf magnetismus reagierendes reagenzes - Google Patents

Magnetisch unterstützter bindungstest unter verwendung eines auf magnetismus reagierendes reagenzes

Info

Publication number
ATE412898T1
ATE412898T1 AT98921225T AT98921225T ATE412898T1 AT E412898 T1 ATE412898 T1 AT E412898T1 AT 98921225 T AT98921225 T AT 98921225T AT 98921225 T AT98921225 T AT 98921225T AT E412898 T1 ATE412898 T1 AT E412898T1
Authority
AT
Austria
Prior art keywords
magnetic field
reaction mixture
responsive reagent
binding test
magnetic assisted
Prior art date
Application number
AT98921225T
Other languages
English (en)
Inventor
Thomas Rohr
Tuan Elstrom
Lawrence Howard
Eric Shain
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE412898T1 publication Critical patent/ATE412898T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/806—Electrical property or magnetic property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/832—Nanostructure having specified property, e.g. lattice-constant, thermal expansion coefficient
    • Y10S977/838—Magnetic property of nanomaterial
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/84—Manufacture, treatment, or detection of nanostructure
    • Y10S977/89—Deposition of materials, e.g. coating, cvd, or ald
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/92—Detection of biochemical
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/932—Specified use of nanostructure for electronic or optoelectronic application
    • Y10S977/953—Detector using nanostructure
    • Y10S977/96—Of magnetic property

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Sampling And Sample Adjustment (AREA)
AT98921225T 1997-05-16 1998-05-15 Magnetisch unterstützter bindungstest unter verwendung eines auf magnetismus reagierendes reagenzes ATE412898T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/857,440 US5998224A (en) 1997-05-16 1997-05-16 Magnetically assisted binding assays utilizing a magnetically responsive reagent

Publications (1)

Publication Number Publication Date
ATE412898T1 true ATE412898T1 (de) 2008-11-15

Family

ID=25326006

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98921225T ATE412898T1 (de) 1997-05-16 1998-05-15 Magnetisch unterstützter bindungstest unter verwendung eines auf magnetismus reagierendes reagenzes

Country Status (8)

Country Link
US (1) US5998224A (de)
EP (2) EP1881325B1 (de)
JP (4) JP4237267B2 (de)
AT (1) ATE412898T1 (de)
CA (1) CA2290018C (de)
DE (1) DE69840166D1 (de)
ES (2) ES2316163T3 (de)
WO (1) WO1998052043A1 (de)

Families Citing this family (122)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19753851A1 (de) * 1997-12-04 1999-06-10 Roche Diagnostics Gmbh Vorrichtung zum kapillaren Flüssigkeitstransport
EP1169646A2 (de) * 1999-01-25 2002-01-09 Minerva Biotechnologies Corporation Schneller und empfindlicher nachweis fehlerhafter proteinaggregation bei neurodegenerativen erkrankungen
EP1198712A2 (de) * 1999-02-17 2002-04-24 Kilian Hennes Verfahren zum darstellen von biologisch aktivierten induktivitätsändernden partikeln sowie vorrichtung dafür
WO2001018235A2 (en) * 1999-09-09 2001-03-15 Eichrom Technologies, Inc. Lateral flow device with metal oxide indicator and assay method employing same
US7537938B2 (en) 2000-04-28 2009-05-26 Monogram Biosciences, Inc. Biomarker detection in circulating cells
US7811768B2 (en) * 2001-01-26 2010-10-12 Aviva Biosciences Corporation Microdevice containing photorecognizable coding patterns and methods of using and producing the same
US7015047B2 (en) * 2001-01-26 2006-03-21 Aviva Biosciences Corporation Microdevices having a preferential axis of magnetization and uses thereof
FR2826882B1 (fr) * 2001-07-09 2003-09-12 Bio Merieux Procede de traitement de particules magnetiques et configurations d'aimants permettant la mise en oeuvre de ce procede
US7169577B2 (en) * 2001-07-27 2007-01-30 Surface Logix, Inc. Cell isolation and screening device and method of using same
US7169578B2 (en) * 2001-07-27 2007-01-30 Surface Logix, Inc. Cell isolation and screening device and method of using same
US7285412B2 (en) * 2001-07-27 2007-10-23 Surface Logix Inc. Device for magnetic immobilization of cells
WO2003072830A1 (en) * 2002-02-22 2003-09-04 Purdue Research Foundation Magnetic nanomaterials and methods for detection of biological materials
US8697029B2 (en) * 2002-04-18 2014-04-15 The Regents Of The University Of Michigan Modulated physical and chemical sensors
EP1532274A4 (de) * 2002-06-28 2006-09-27 Purdue Research Foundation Magnetische nanomaterialien und verfahren zum nachweis biologischer materialien
US7601491B2 (en) 2003-02-06 2009-10-13 Becton, Dickinson And Company Pretreatment method for extraction of nucleic acid from biological samples and kits therefor
CN1280428C (zh) * 2003-05-19 2006-10-18 清华大学 一种基于微小颗粒的生物芯片系统及其应用
FR2855613B1 (fr) * 2003-05-26 2005-08-19 Biocytex Procede de detection et de quantification multiplex d'analytes dans un echantillon a l'aide de microspheres
US7402398B2 (en) 2003-07-17 2008-07-22 Monogram Biosciences, Inc. Measuring receptor homodimerization
WO2005019470A2 (en) 2003-08-11 2005-03-03 Monogram Biosciences, Inc. Detecting and profiling molecular complexes
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US20050282182A1 (en) * 2003-12-30 2005-12-22 Universal Bio Research Co., Ltd. Reaction vessel and reaction apparatus comprising three-dimensional particle array
JP2005315677A (ja) * 2004-04-28 2005-11-10 Canon Inc 検出装置および検出方法
DE102004033811A1 (de) * 2004-07-12 2006-02-02 Salama, Abdulgabar, Prof. Dr. Verfahren zum einfachen und schnellen Nachweis von Zellen und Biomolekülen mit Hilfe paramagnetischer Partikel
WO2006127694A2 (en) 2004-07-13 2006-11-30 Dexcom, Inc. Analyte sensor
US20060020192A1 (en) 2004-07-13 2006-01-26 Dexcom, Inc. Transcutaneous analyte sensor
US20060024776A1 (en) * 2004-08-02 2006-02-02 Mcmillian Ray Magnetic particle capture of whole intact organisms from clinical samples
CA2587085C (en) 2004-10-27 2017-08-08 Cepheid Closed-system multi-stage nucleic acid amplification reactions
US7939267B2 (en) * 2004-11-04 2011-05-10 Laboratory Corporation Of America Holdings Detection of activation of endothelial cells as surrogate marker for angiogenesis
BRPI0607213B1 (pt) 2005-01-28 2017-04-04 Univ Duke aparelho para manipulação de gotículas em uma placa de circuito impresso
EP1705486B1 (de) 2005-02-05 2008-03-19 Samsung Electronics Co., Ltd. Sensorschalter und seine Verwendung in einem Nachweisverfahren
US7781228B2 (en) 2005-04-07 2010-08-24 Menon & Associates, Inc. Magnetic resonance system and method to detect and confirm analytes
US7300631B2 (en) 2005-05-02 2007-11-27 Bioscale, Inc. Method and apparatus for detection of analyte using a flexural plate wave device and magnetic particles
US7263874B2 (en) * 2005-06-08 2007-09-04 Bioscale, Inc. Methods and apparatus for determining properties of a fluid
US20060281104A1 (en) * 2005-06-13 2006-12-14 Macevicz Stephen C Leuco dye particles and uses thereof
US20070020699A1 (en) * 2005-07-19 2007-01-25 Idexx Laboratories, Inc. Lateral flow assay and device using magnetic particles
US9488665B2 (en) * 2005-09-13 2016-11-08 Chrome Red Technologies, Llc Magnetic particle tagged reagents and techniques
US20070059782A1 (en) * 2005-09-13 2007-03-15 Graham Henry A Magnetic particle tagged blood bank reagents and techniques
US20070166730A1 (en) 2006-01-19 2007-07-19 Menon & Associates, Inc. Magnetic resonance system and method to detect and confirm analytes
EP2000484B1 (de) * 2006-03-27 2011-11-30 Tokyo Institute of Technology Verfahren zur herstellung von polymerbeschichtetem ferromagnetischem teilchen und polymerbeschichtetes ferromagnetisches teilchen
US9476856B2 (en) * 2006-04-13 2016-10-25 Advanced Liquid Logic, Inc. Droplet-based affinity assays
US8492168B2 (en) * 2006-04-18 2013-07-23 Advanced Liquid Logic Inc. Droplet-based affinity assays
US20140193807A1 (en) 2006-04-18 2014-07-10 Advanced Liquid Logic, Inc. Bead manipulation techniques
US7439014B2 (en) 2006-04-18 2008-10-21 Advanced Liquid Logic, Inc. Droplet-based surface modification and washing
US7851184B2 (en) * 2006-04-18 2010-12-14 Advanced Liquid Logic, Inc. Droplet-based nucleic acid amplification method and apparatus
US8809068B2 (en) 2006-04-18 2014-08-19 Advanced Liquid Logic, Inc. Manipulation of beads in droplets and methods for manipulating droplets
US10078078B2 (en) 2006-04-18 2018-09-18 Advanced Liquid Logic, Inc. Bead incubation and washing on a droplet actuator
US8637324B2 (en) 2006-04-18 2014-01-28 Advanced Liquid Logic, Inc. Bead incubation and washing on a droplet actuator
US7901947B2 (en) 2006-04-18 2011-03-08 Advanced Liquid Logic, Inc. Droplet-based particle sorting
US8900828B2 (en) 2006-05-01 2014-12-02 Cepheid Methods and apparatus for sequential amplification reactions
WO2009111769A2 (en) 2008-03-07 2009-09-11 Advanced Liquid Logic, Inc. Reagent and sample preparation and loading on a fluidic device
US8119352B2 (en) * 2006-06-20 2012-02-21 Cepheld Multi-stage amplification reactions by control of sequence replication times
EP2044402B2 (de) * 2006-07-24 2016-11-30 Becton Dickinson and Company Vorrichtung und Verfahren zur Durchführung eines Assays mittels magnetischer Partikeln.
WO2008098236A2 (en) 2007-02-09 2008-08-14 Advanced Liquid Logic, Inc. Droplet actuator devices and methods employing magnetic beads
US9068977B2 (en) * 2007-03-09 2015-06-30 The Regents Of The University Of Michigan Non-linear rotation rates of remotely driven particles and uses thereof
WO2011084703A2 (en) 2009-12-21 2011-07-14 Advanced Liquid Logic, Inc. Enzyme assays on a droplet actuator
US8702938B2 (en) 2007-09-04 2014-04-22 Advanced Liquid Logic, Inc. Droplet actuator with improved top substrate
CA2709928A1 (en) 2007-12-23 2009-07-09 Advanced Liquid Logic, Inc. Droplet actuator configurations and methods of conducting droplet operations
US7927561B2 (en) * 2008-01-10 2011-04-19 Becton, Dickinson And Company Rapid particle detection assay
CN101971015A (zh) 2008-01-17 2011-02-09 加利福尼亚大学董事会 集成的磁场产生和检测平台
WO2009126649A2 (en) * 2008-04-07 2009-10-15 Life Bioscience, Inc. Method of providing particles having biological-binding areas for biological applications
US8852952B2 (en) 2008-05-03 2014-10-07 Advanced Liquid Logic, Inc. Method of loading a droplet actuator
US8926065B2 (en) 2009-08-14 2015-01-06 Advanced Liquid Logic, Inc. Droplet actuator devices and methods
US9091649B2 (en) 2009-11-06 2015-07-28 Advanced Liquid Logic, Inc. Integrated droplet actuator for gel; electrophoresis and molecular analysis
WO2011100358A2 (en) * 2010-02-09 2011-08-18 Fabrico Technology, Inc. Systems and methods for detecting target analytes
US10126296B2 (en) 2010-08-05 2018-11-13 Abbott Point Of Care Inc. Immunoassay method and device with magnetically susceptible bead capture
US11402375B2 (en) 2010-08-05 2022-08-02 Abbott Point Of Care Inc. Magnetic immunosensor with trench configuration and method of use
US9233370B2 (en) 2010-08-05 2016-01-12 Abbott Point Of Care Inc. Magnetic immunosensor and method of use
US9329175B2 (en) 2010-08-05 2016-05-03 Abbott Point Of Care Inc. Oscillating immunoassay method and device
WO2012027747A2 (en) 2010-08-27 2012-03-01 The Regents Of The University Of Michigan Asynchronous magnetic bead rotation sensing systems and methods
US20120077184A1 (en) * 2010-09-28 2012-03-29 Starkdx Incorporated Electromagnetic multiplex assay biosensor
WO2012142179A2 (en) 2011-04-11 2012-10-18 The Regents Of The University Of Michigan Magnetically induced microspinning for super-detection and super-characterization of biomarkers and live cells
EP2707131B1 (de) 2011-05-09 2019-04-24 Advanced Liquid Logic, Inc. Mikrofluidische rückkopplung mittels impedanzerkennung
EP2729792A4 (de) 2011-07-06 2015-03-18 Advanced Liquid Logic Inc Reagenzienaufbewahrung auf einem tröpfchenaktuator
WO2013009927A2 (en) 2011-07-11 2013-01-17 Advanced Liquid Logic, Inc. Droplet actuators and techniques for droplet-based assays
US9446404B2 (en) 2011-07-25 2016-09-20 Advanced Liquid Logic, Inc. Droplet actuator apparatus and system
JP2013088164A (ja) * 2011-10-14 2013-05-13 Hitachi High-Technologies Corp 自動分析装置
WO2013078216A1 (en) 2011-11-21 2013-05-30 Advanced Liquid Logic Inc Glucose-6-phosphate dehydrogenase assays
US9797817B2 (en) 2012-05-03 2017-10-24 The Regents Of The University Of Michigan Multi-mode separation for target detection
EP2664914A1 (de) * 2012-05-16 2013-11-20 Koninklijke Philips N.V. Magnetisch unterstützte Verarbeitung eines Mediums
BR112014032727B1 (pt) 2012-06-27 2021-12-14 Illumina France Método e sistema para realizar operações de gotícula em uma gotícula em um atuador de gotículas para redução da formação de bolhas
WO2014007248A1 (ja) * 2012-07-06 2014-01-09 凸版印刷株式会社 被検物質の検出システム
JP6120518B2 (ja) * 2012-10-10 2017-04-26 公益財団法人かずさＤｎａ研究所 簡易測定器具
US20160296945A1 (en) 2013-03-15 2016-10-13 Ancera, Inc. Systems and methods for active particle separation
WO2014145765A1 (en) * 2013-03-15 2014-09-18 Ancera, Inc. Systems and methods for bead-based assays in ferrofluids
JP6420055B2 (ja) * 2013-03-29 2018-11-07 積水メディカル株式会社 イムノクロマト用着色粒子及びこれを用いた診断用イムノクロマト試薬
US9983110B2 (en) 2013-11-04 2018-05-29 The Regents Of The University Of Michigan Asynchronous magnetic bead rotation (AMBR) microviscometer for analysis of analytes
EP3249055B1 (de) * 2013-12-12 2019-06-26 Altratech Limited Nukleinsäureanalyseverfahren und -vorrichtung
US10533170B2 (en) * 2014-03-14 2020-01-14 Shimadzu Corporation Method for manipulating magnetic particles and device for manipulating magnetic particles
JP6574207B2 (ja) 2014-05-05 2019-09-11 スリーディー グラス ソリューションズ，インク３Ｄ Ｇｌａｓｓ Ｓｏｌｕｔｉｏｎｓ，Ｉｎｃ 光活性基板を製造する、２ｄ及び３ｄインダクタ、アンテナ、並びにトランス
WO2015177933A1 (ja) * 2014-05-23 2015-11-26 株式会社島津製作所 磁性体粒子の操作方法および磁性体粒子操作用デバイス
WO2016013115A1 (ja) * 2014-07-25 2016-01-28 株式会社 リージャー 希釈生体試料成分の分析方法
KR101860543B1 (ko) * 2015-01-09 2018-05-24 한양대학교 에리카산학협력단 성호르몬 검출용 시약 키트 및 이를 이용한 성호르몬 검출 방법
US11285490B2 (en) 2015-06-26 2022-03-29 Ancera, Llc Background defocusing and clearing in ferrofluid-based capture assays
JP6865466B2 (ja) * 2015-06-26 2021-04-28 株式会社カワノラボ 分散質分析方法、および分析装置
WO2017052506A1 (en) * 2015-09-22 2017-03-30 Halliburton Energy Services, Inc. Optical device window cleaning system
US10070533B2 (en) 2015-09-30 2018-09-04 3D Glass Solutions, Inc. Photo-definable glass with integrated electronics and ground plane
KR20180134868A (ko) 2016-02-25 2018-12-19 3디 글래스 솔루션즈 인코포레이티드 3d 커패시터 및 커패시터 어레이 제작용 광활성 기재
WO2017177171A1 (en) 2016-04-08 2017-10-12 3D Glass Solutions, Inc. Methods of fabricating photosensitive substrates suitable for optical coupler
KR101994370B1 (ko) * 2016-08-24 2019-06-28 주식회사 제놉시 항체 및 자성 나노 입자가 결합된 전도성 고분자를 포함하는 혈중 암세포 검출 및 회수용 자성 나노 구조체
US10845449B2 (en) 2016-10-20 2020-11-24 Quantum Diamond Technologies Inc. Methods and apparatus for magnetic particle analysis using diamond magnetic imaging
US10590409B2 (en) * 2016-12-06 2020-03-17 Wisconsin Alumni Research Foundation Method and device for disaggregation via heterogeneous particles
JP7249281B2 (ja) 2016-12-23 2023-03-30 クアンタム ダイヤモンド テクノロジーズ インク． 磁気式多ビーズアッセイのための方法および装置
KR102420212B1 (ko) 2017-04-28 2022-07-13 3디 글래스 솔루션즈 인코포레이티드 Ｒｆ 서큘레이터
AU2018297035B2 (en) 2017-07-07 2021-02-25 3D Glass Solutions, Inc. 2D and 3D RF lumped element devices for RF system in a package photoactive glass substrates
JP7204733B2 (ja) 2017-07-31 2023-01-16 クアンタム ダイヤモンド テクノロジーズ インク． 試料測定のための方法および装置
CA3084818C (en) 2017-12-15 2023-01-17 3D Glass Solutions, Inc. Coupled transmission line resonate rf filter
WO2019136024A1 (en) 2018-01-04 2019-07-11 3D Glass Solutions, Inc. Impedance matching conductive structure for high efficiency rf circuits
JP7272348B2 (ja) * 2018-03-20 2023-05-12 住友電気工業株式会社 微小粒子計測装置
KR102145746B1 (ko) 2018-04-10 2020-08-19 3디 글래스 솔루션즈 인코포레이티드 Rf 집적형 전력 조절 커패시터
KR102475010B1 (ko) 2018-05-29 2022-12-07 3디 글래스 솔루션즈 인코포레이티드 저 삽입 손실 rf 전송 라인
JP7320845B2 (ja) * 2018-06-08 2023-08-04 国立研究開発法人産業技術総合研究所 標的物質検出方法及び標的物質検出キット
EP3853944B1 (de) 2018-09-17 2023-08-02 3D Glass Solutions, Inc. Hocheffiziente kompakte schlitzantenne mit grundplatte
AU2019416327B2 (en) 2018-12-28 2021-12-09 3D Glass Solutions, Inc. Annular capacitor RF, microwave and MM wave systems
KR102642603B1 (ko) 2018-12-28 2024-03-05 3디 글래스 솔루션즈 인코포레이티드 광활성 유리 기판들에서 ｒｆ, 마이크로파, 및 ｍｍ 파 시스템들을 위한 이종 통합
US11962057B2 (en) 2019-04-05 2024-04-16 3D Glass Solutions, Inc. Glass based empty substrate integrated waveguide devices
EP3948954B1 (de) 2019-04-18 2023-06-14 3D Glass Solutions, Inc. Hocheffiziente chipvereinzelung und -ausgabe
WO2020225900A1 (ja) * 2019-05-09 2020-11-12 三菱電機株式会社 磁性摩耗粉量測定装置及び機械装置
CA3177603C (en) 2020-04-17 2024-01-09 3D Glass Solutions, Inc. Broadband induction
WO2021230821A1 (en) * 2020-05-12 2021-11-18 National University Of Singapore A method for virus and biomarker detection
RU200521U1 (ru) * 2020-05-26 2020-10-28 Алексей Николаевич Темников Портативный сканер-дисплей магнитного поля
EP4252907A1 (de) * 2022-03-30 2023-10-04 Blink AG Verfahren zur anordnung von mikrokugeln in einer nichtwässrigen flüssigen phase

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985649A (en) * 1974-11-25 1976-10-12 Eddelman Roy T Ferromagnetic separation process and material
US4070246A (en) * 1976-04-09 1978-01-24 Abbott Laboratories Reactive matrices
GB8401368D0 (en) * 1984-01-19 1984-02-22 Amersham Int Plc Assay method
US5076950A (en) * 1985-12-20 1991-12-31 Syntex (U.S.A.) Inc. Magnetic composition for particle separation
JPH0614051B2 (ja) * 1986-02-10 1994-02-23 株式会社ニッテク 抗原―抗体不溶化担体の選別方法
US4960691A (en) * 1986-09-29 1990-10-02 Abbott Laboratories Chromatographic test strip for determining ligands or receptors
JPS63108264A (ja) * 1986-10-25 1988-05-13 Nippon Telegr & Teleph Corp <Ntt> 磁気免疫測定方法および該方法を実施するために使用する検査試薬片
US5236824A (en) * 1988-04-26 1993-08-17 Nippon Telegraph And Telephone Corporation Laser magnetic immunoassay method and method by a magnetophoresis apparatus therefor
JP2599175B2 (ja) * 1988-04-26 1997-04-09 日本電信電話株式会社 レーザ磁気免疫測定方法及び測定装置並びにレーザ磁気免疫測定に用いる超常磁性体標識体及びその製造方法
US5145784A (en) * 1988-05-04 1992-09-08 Cambridge Biotech Corporation Double capture assay method employing a capillary flow device
US5108933A (en) * 1988-09-16 1992-04-28 Immunicon Corporation Manipulation of colloids for facilitating magnetic separations
US5252459A (en) * 1988-09-23 1993-10-12 Abbott Laboratories Indicator reagents, diagnostic assays and test kits employing organic polymer latex particles
CA1335181C (en) * 1988-10-11 1995-04-11 R. Alan Hardwick System for selective cell separation from cell concentrate
TW221493B (de) * 1990-07-10 1994-03-01 Cardiovascular Diagnostics Inc
JPH0552849A (ja) * 1991-08-28 1993-03-02 Terumo Corp 検体の特異的検出および特異的分離方法
WO1993019370A1 (en) * 1992-03-20 1993-09-30 Abbott Laboratories Magnetically assisted binding assays using magnetically-labeled binding members
WO1993019371A1 (en) * 1992-03-20 1993-09-30 Abbott Laboratories Determination of binding affinity using magneticaly-labeled binding members
US5445971A (en) * 1992-03-20 1995-08-29 Abbott Laboratories Magnetically assisted binding assays using magnetically labeled binding members
US5445970A (en) * 1992-03-20 1995-08-29 Abbott Laboratories Magnetically assisted binding assays using magnetically labeled binding members
JP3298882B2 (ja) * 1992-05-01 2002-07-08 トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルベニア 微細加工した検出構造体
US5358659A (en) * 1992-07-09 1994-10-25 Xerox Corporation Magnetic materials with single-domain and multidomain crystallites and a method of preparation
US5322756A (en) * 1992-07-09 1994-06-21 Xerox Corporation Magnetic fluids and method of preparation
AU6357394A (en) * 1993-03-04 1994-09-26 Sapidyne, Inc. Assay flow apparatus and method
US5374531A (en) * 1993-03-22 1994-12-20 Zynaxis, Inc. Immunoassay for determination of cells
FR2708348B1 (fr) * 1993-07-28 1995-10-06 Stago Diagnostica Procédé de dosage d'une substance immunologique au moyen de particules de latex magnétiques et de particules non-magnétiques.
GB9409333D0 (en) 1994-05-10 1994-06-29 Palmer Richard F Analytical method and device for use therein
US5656429A (en) * 1994-10-03 1997-08-12 Adelman; Lonnie W. Polynucleotide and protein analysis method using magnetizable moieties
FR2732116B1 (fr) * 1995-03-21 1997-05-09 Bio Merieux Procede et dispositif pour la determination qualitative et/ou quantitative d'un analyte, notamment d'une bacterie, dans un echantillon, par voie magnetique
JPH08304399A (ja) * 1995-04-28 1996-11-22 Mitsubishi Chem Corp 磁性体粒子の分離方法およびそれを用いた免疫分析方法

Also Published As

Publication number Publication date
WO1998052043A1 (en) 1998-11-19
ES2316163T3 (es) 2009-04-01
DE69840166D1 (de) 2008-12-11
JP2008003083A (ja) 2008-01-10
JP2002504993A (ja) 2002-02-12
JP4237267B2 (ja) 2009-03-11
CA2290018A1 (en) 1998-11-19
EP1881325A1 (de) 2008-01-23
US5998224A (en) 1999-12-07
EP0981749B1 (de) 2008-10-29
JP4806457B2 (ja) 2011-11-02
CA2290018C (en) 2011-07-19
EP0981749A1 (de) 2000-03-01
ES2378782T3 (es) 2012-04-17
JP4324212B2 (ja) 2009-09-02
EP1881325B1 (de) 2012-01-11
JP2009204617A (ja) 2009-09-10
JP2011257413A (ja) 2011-12-22

Similar Documents

Publication Publication Date Title
ATE412898T1 (de) Magnetisch unterstützter bindungstest unter verwendung eines auf magnetismus reagierendes reagenzes
TW356519B (en) A device for highest sensitivity magnetic detection of analytes
BG104275A (en) Method and device for express analysis of tested parameters in biological samples
ES2079434T3 (es) Ensayos de ligandos-receptores que utilizan un umbral.
DK0570518T3 (da) Fremgangsmåder og apparat til forbedrede elektrokemiluminescens-assays
DK0878713T3 (da) Fremgangsmåde og apparat til korrektion af omgivelsestemperaturindflydelse i biosensorer
EP0417305A4 (en) Analyzer of liquid sample and analyzing method of liquid sample using said analyzer
DE60332539D1 (de) Membran-basierendes verfahren unter verwendung von zeitaufgelösten fluoreszenzmessungen
DE69809752T2 (de) Vorrichtung zum testen der analytkonzentration in einer flüssigkeit
DK0779367T3 (da) Analyseindretning med stabilt koblingsfarvestof til fotometrisk bestemmelse af analytter
DK1111386T3 (da) Teststrimmel til bestemmelse af en analyt i en flydende pröve
DE69519160D1 (de) Verfahren zur quantitativen analyse von cholesterin
DK1031036T3 (da) Apparat og fremgangsmåde til detektion af et analysemateriale
NZ306051A (en) Testing using electrochemiluminescence
ES2050697T3 (es) Metodos y dispositivos de ensayo de fijacion cromatografico.
ES2109802T3 (es) Dispositivo de ensayo y su fabricacion.
DE59107707D1 (de) Analysesystem und Verfahren zur Bestimmung eines Analyten in einer fluiden Probe
DK406087D0 (da) Fremgangsmaade og testkit til bestemmelse af koncentrationen af en i en biologisk vaeske vaerende aktiv forbindelse
NO20003709L (no) Fremgangsmate for detektering av en analytt, og omsluttingsmiddel og kit for anvendelse deri
ATE287084T1 (de) Immunoassay verfahren und testsatz
DK476489A (da) Fremgangsmaade til bestemmelse af en maengde antigen og antistof
KR870005248A (ko) 결합가능한 분석물을 정량하는 방법 및 시약
DE69533586D1 (de) Verfahren zum testen eines asialoglycoproteinrezeptors und testreagenz dafür
BR9400447A (pt) Processo de teste tipo sanfuíche para determinar um antígeno ou anticorpo em uma amostra de teste e equipamento diagnóstico para realizar o teste
DK563588D0 (da) Proevningsapparat til brug ved proevning for en analysand

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties