DE69837390T2 - Rekombinanter schweine adenovirus vektor - Google Patents

Rekombinanter schweine adenovirus vektor Download PDF

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Publication number
DE69837390T2
DE69837390T2 DE69837390T DE69837390T DE69837390T2 DE 69837390 T2 DE69837390 T2 DE 69837390T2 DE 69837390 T DE69837390 T DE 69837390T DE 69837390 T DE69837390 T DE 69837390T DE 69837390 T2 DE69837390 T2 DE 69837390T2
Authority
DE
Germany
Prior art keywords
recombinant
pav
vector
porcine
pigs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69837390T
Other languages
German (de)
English (en)
Other versions
DE69837390D1 (de
Inventor
Michael Anthony Thornbury JOHNSON
Jeffrey Michael Jan Juc HAMMOND
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commonwealth Scientific and Industrial Research Organisation
Australian Pork Ltd
Original Assignee
Commonwealth Scientific and Industrial Research Organisation
Pig Research and Development Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3802849&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69837390(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Commonwealth Scientific and Industrial Research Organisation, Pig Research and Development Corp filed Critical Commonwealth Scientific and Industrial Research Organisation
Publication of DE69837390D1 publication Critical patent/DE69837390D1/de
Application granted granted Critical
Publication of DE69837390T2 publication Critical patent/DE69837390T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/235—Adenoviridae
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69837390T 1997-08-14 1998-08-14 Rekombinanter schweine adenovirus vektor Expired - Lifetime DE69837390T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPO8560A AUPO856097A0 (en) 1997-08-14 1997-08-14 Vector
AUPO856097 1997-08-14
PCT/AU1998/000648 WO1999008706A1 (en) 1997-08-14 1998-08-14 Recombinant porcine adenovirus vector

Publications (2)

Publication Number Publication Date
DE69837390D1 DE69837390D1 (de) 2007-05-03
DE69837390T2 true DE69837390T2 (de) 2007-08-23

Family

ID=3802849

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69837390T Expired - Lifetime DE69837390T2 (de) 1997-08-14 1998-08-14 Rekombinanter schweine adenovirus vektor

Country Status (17)

Country Link
US (3) US7323177B1 (enExample)
EP (2) EP1825863A1 (enExample)
JP (2) JP4365023B2 (enExample)
KR (1) KR100746524B1 (enExample)
CN (1) CN100366292C (enExample)
AT (1) ATE357250T1 (enExample)
AU (2) AUPO856097A0 (enExample)
BR (1) BR9811184A (enExample)
CY (1) CY1106565T1 (enExample)
DE (1) DE69837390T2 (enExample)
DK (1) DK1007088T3 (enExample)
ES (1) ES2283068T3 (enExample)
ID (1) ID24174A (enExample)
MX (1) MXPA00001562A (enExample)
NZ (1) NZ503039A (enExample)
PT (1) PT1007088E (enExample)
WO (1) WO1999008706A1 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO856097A0 (en) * 1997-08-14 1997-09-04 Commonwealth Scientific And Industrial Research Organisation Vector
US6492343B1 (en) * 1998-04-15 2002-12-10 University Of Saskatchewan Porcine adenovirus type 3 genome
FR2789695B1 (fr) 1999-02-11 2003-03-07 Merial Sas Vecteurs et vaccins viraux a base d'adenovirus porcins recombines et replicatifs
FR2804028B1 (fr) * 2000-01-21 2004-06-04 Merial Sas Vaccins adn ameliores pour animaux de rente
WO2001083737A2 (en) * 2000-05-03 2001-11-08 University Of Guelph Porcine adenovirus type 5 vector and vaccine
WO2002031168A2 (en) * 2000-10-10 2002-04-18 Genstar Therapeutics Minimal adenoviral vector and recombinant vaccines based thereon
MY146518A (en) 2001-03-27 2012-08-15 Univ Saskatchewan Methods to culture circovirus.
WO2003013598A2 (en) * 2001-08-09 2003-02-20 Lam Dominic M K Novel vaccine compositions and methods of vaccine preparation for veterinary and human diseases
WO2003023026A1 (en) 2001-09-06 2003-03-20 Alphavax, Inc. Alphavirus replicon vector systems
JP3949520B2 (ja) * 2001-09-20 2007-07-25 独立行政法人科学技術振興機構 レギュカルチン過剰発現モデル動物
US7569217B2 (en) 2001-09-24 2009-08-04 University Of Saskatchewan Porcine adenovirus E1 and E4 regions
KR20030054139A (ko) * 2001-12-24 2003-07-02 학교법인 건국대학교 돼지 오제스키병 바이러스의 ｇＤ 유전자를 포함하는재조합 발현 벡터 및 이를 이용한 ＤＮＡ 백신
US7906311B2 (en) 2002-03-20 2011-03-15 Merial Limited Cotton rat lung cells for virus culture
AU2003297039B2 (en) 2002-12-13 2009-03-05 Alphavax, Inc. Multi-antigenic alphavirus replicon particles and methods
AU2003297041B2 (en) 2002-12-13 2009-02-26 Alphavax, Inc. Alphavirus particles and methods for preparation
EP1608762B1 (en) 2003-03-20 2014-01-08 Alphavax, Inc. Improved alphavirus replicons and helper constructs
PT1651666E (pt) 2003-07-11 2009-08-28 Alphavax Inc Vacinas de citomegalovírus à base de alfavírus
PT1751289E (pt) 2004-05-18 2009-03-31 Alphavax Inc Vectores de alfavirais derivados da tc-83, partículas e métodos
CN101277717A (zh) * 2005-09-09 2008-10-01 英特威国际有限公司 Pcv-2疫苗
CN101849012A (zh) * 2006-07-28 2010-09-29 联邦科学和工业研究组织 用于增加重组腺病毒载体的组织嗜性的方法和组合物
DK2947149T3 (en) 2007-06-21 2018-06-06 Alphavax Inc ALPHAVIRUS REPLICATION PARTICLES FOR USE IN VACCINATION
US20100150959A1 (en) * 2008-12-15 2010-06-17 Vectogen Pty Ltd. PCV 2-Based Methods and Compositions for the Treatment of Pigs
US20110135688A1 (en) * 2009-12-04 2011-06-09 Michael Sheppard Methods and Compositions for Increasing Titer of Recombinant Porcine Adenovirus-3 Vectors
MX2014013964A (es) * 2012-05-17 2015-03-04 Zoetis Llc Vacunacion eficaz contral el virus del sindrome reproductivo y respiratorio porcino (prrs) antes del destete.
EP3107568B1 (en) * 2014-02-20 2024-03-27 Vaxart, Inc. Formulations for small intestinal delivery
KR102678401B1 (ko) 2015-06-12 2024-06-26 박사르트, 인크. Rsv 및 노로바이러스 항원들의 소장 내의 전달을 위한 제형들
UA124976C2 (uk) 2016-12-14 2021-12-22 Зоетіс Сервісіз Ллс Вакцина для захисту тварини свині від зараження вірусом prrs
CN110904127B (zh) * 2018-09-18 2024-09-20 瓦赫宁恩研究基金会 非洲猪瘟病毒疫苗
WO2022155500A1 (en) 2021-01-14 2022-07-21 Senti Biosciences, Inc. Secretable payload regulation
CN116004550A (zh) * 2022-08-03 2023-04-25 石河子大学 猪轮状病毒重组腺病毒及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4320068C1 (de) 1993-06-17 1994-12-15 Audi Ag Verfahren und Vorrichtung zur Reparatur von Fahrzeugkarosserien aus Leichtmetallteilen
CA2144040A1 (fr) * 1993-07-13 1995-01-26 Michel Perricaudet Vecteurs adenoviraux defectifs et utilisation en therapie genique
WO1996002697A1 (en) 1994-07-14 1996-02-01 Union Camp Patent Holding, Inc. Improved bleaching of high consistency lignocellulosic pulp
FR2725213B1 (fr) * 1994-10-04 1996-11-08 Rhone Poulenc Rorer Sa Vecteurs viraux et utilisation en therapie genique
ES2105984B1 (es) * 1995-11-30 1998-04-16 Iberica Cyanamid Adenovirus recombinantes que expresan antigenos del virus de la gastroenteritis porcina transmisible (vgpt) y su empleo en la formacion de vacunas.
AUPO856097A0 (en) * 1997-08-14 1997-09-04 Commonwealth Scientific And Industrial Research Organisation Vector
US6492343B1 (en) * 1998-04-15 2002-12-10 University Of Saskatchewan Porcine adenovirus type 3 genome

Also Published As

Publication number Publication date
WO1999008706A8 (en) 2000-08-10
ES2283068T3 (es) 2007-10-16
EP1825863A1 (en) 2007-08-29
EP1007088B1 (en) 2007-03-21
AU2011224111A1 (en) 2011-10-13
US7323177B1 (en) 2008-01-29
BR9811184A (pt) 2001-12-26
DK1007088T3 (da) 2007-06-04
DE69837390D1 (de) 2007-05-03
EP1007088A4 (en) 2003-01-08
CN1275084A (zh) 2000-11-29
JP4365023B2 (ja) 2009-11-18
WO1999008706A1 (en) 1999-02-25
ATE357250T1 (de) 2007-04-15
CN100366292C (zh) 2008-02-06
MXPA00001562A (es) 2004-10-14
EP1007088A1 (en) 2000-06-14
US20090226485A1 (en) 2009-09-10
KR20010022882A (ko) 2001-03-26
HK1032755A1 (zh) 2001-08-03
NZ503039A (en) 2002-09-27
KR100746524B1 (ko) 2007-08-07
JP2009213495A (ja) 2009-09-24
US7473428B2 (en) 2009-01-06
US7785602B2 (en) 2010-08-31
CY1106565T1 (el) 2012-01-25
PT1007088E (pt) 2007-05-31
ID24174A (id) 2000-07-13
JP2001514871A (ja) 2001-09-18
US20060263387A1 (en) 2006-11-23
AUPO856097A0 (en) 1997-09-04

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Legal Events

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8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: AUSTRALIAN PORK LTD., DEAKIN, AU

Owner name: COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARC, AU