PL2947149T3 - Kasety bez promotora do ekspresji alfawirusowych białek strukturalnych - Google Patents
Kasety bez promotora do ekspresji alfawirusowych białek strukturalnychInfo
- Publication number
- PL2947149T3 PL2947149T3 PL15173487T PL15173487T PL2947149T3 PL 2947149 T3 PL2947149 T3 PL 2947149T3 PL 15173487 T PL15173487 T PL 15173487T PL 15173487 T PL15173487 T PL 15173487T PL 2947149 T3 PL2947149 T3 PL 2947149T3
- Authority
- PL
- Poland
- Prior art keywords
- vaccination
- alphavirus replicon
- replicon particles
- particles
- alphavirus
- Prior art date
Links
- 241000710929 Alphavirus Species 0.000 title 1
- 239000002245 particle Substances 0.000 title 1
- 238000002255 vaccination Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/275—Poxviridae, e.g. avipoxvirus
- A61K39/285—Vaccinia virus or variola virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36141—Use of virus, viral particle or viral elements as a vector
- C12N2770/36143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Mycology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93663707P | 2007-06-21 | 2007-06-21 | |
| EP15173487.8A EP2947149B1 (en) | 2007-06-21 | 2008-06-20 | Alphavirus replicon particles for use in vaccination |
| EP08825920.5A EP2183368B1 (en) | 2007-06-21 | 2008-06-20 | Promoterless cassettes for expression of alphavirus structural proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2947149T3 true PL2947149T3 (pl) | 2018-09-28 |
Family
ID=40156867
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL15173487T PL2947149T3 (pl) | 2007-06-21 | 2008-06-20 | Kasety bez promotora do ekspresji alfawirusowych białek strukturalnych |
| PL08825920.5T PL2183368T3 (pl) | 2007-06-21 | 2008-06-20 | Kasety bez promotora do ekspresji alfawirusowych białek strukturalnych |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL08825920.5T PL2183368T3 (pl) | 2007-06-21 | 2008-06-20 | Kasety bez promotora do ekspresji alfawirusowych białek strukturalnych |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US7850977B2 (pl) |
| EP (2) | EP2947149B1 (pl) |
| JP (3) | JP5602624B2 (pl) |
| CN (1) | CN101802199B (pl) |
| AU (1) | AU2008266807B2 (pl) |
| CA (1) | CA2689588C (pl) |
| DK (2) | DK2183368T3 (pl) |
| ES (2) | ES2588906T3 (pl) |
| IL (1) | IL202720A (pl) |
| NZ (1) | NZ582495A (pl) |
| PL (2) | PL2947149T3 (pl) |
| WO (1) | WO2008156829A2 (pl) |
| ZA (1) | ZA200909080B (pl) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2947149T3 (pl) * | 2007-06-21 | 2018-09-28 | Alphavax, Inc. | Kasety bez promotora do ekspresji alfawirusowych białek strukturalnych |
| EP2370584B1 (en) | 2008-12-01 | 2014-11-05 | Alphavax, Inc. | Use of microRNAs to control virus helper nucleic acids |
| AU2010234362B2 (en) | 2009-04-08 | 2015-11-26 | Alphavax, Inc. | Alphavirus replicon particles expressing TRP2 |
| ES2586580T3 (es) | 2010-07-06 | 2016-10-17 | Glaxosmithkline Biologicals Sa | Inmunización de mamíferos grandes con dosis bajas de ARN |
| ES2646669T3 (es) | 2010-07-06 | 2017-12-14 | Glaxosmithkline Biologicals Sa | Procedimientos de aumento de una respuesta inmunitaria mediante el suministro de ARN |
| HUE026646T2 (en) | 2010-07-06 | 2016-07-28 | Glaxosmithkline Biologicals Sa | Preferred liposomes containing lipids of PKA value for delivery of RNA |
| DK4226941T3 (da) | 2010-08-31 | 2024-12-02 | Glaxosmithkline Biologicals Sa | Pegylerede liposomer til levering af immunogen-kodende rna |
| KR102266691B1 (ko) * | 2010-10-11 | 2021-06-23 | 노파르티스 아게 | 항원 전달 플랫폼 |
| DE12722942T1 (de) | 2011-03-31 | 2021-09-30 | Modernatx, Inc. | Freisetzung und formulierung von manipulierten nukleinsäuren |
| US11896636B2 (en) | 2011-07-06 | 2024-02-13 | Glaxosmithkline Biologicals Sa | Immunogenic combination compositions and uses thereof |
| US10494421B2 (en) | 2014-02-10 | 2019-12-03 | Univercells Nv | System, apparatus and method for biomolecules production |
| PL3350333T3 (pl) | 2015-09-17 | 2022-03-07 | Modernatx, Inc. | Polinukleotydy zawierające region stabilizujący ogon |
| CN113181106A (zh) | 2016-01-11 | 2021-07-30 | 沃达瑞公司 | 微针组合物及其使用方法 |
| WO2017162265A1 (en) * | 2016-03-21 | 2017-09-28 | Biontech Rna Pharmaceuticals Gmbh | Trans-replicating rna |
| WO2017162266A1 (en) * | 2016-03-21 | 2017-09-28 | Biontech Rna Pharmaceuticals Gmbh | Rna replicon for versatile and efficient gene expression |
| US10538786B2 (en) | 2016-04-13 | 2020-01-21 | Janssen Pharmaceuticals, Inc. | Recombinant arterivirus replicon systems and uses thereof |
| US12385034B2 (en) | 2016-06-24 | 2025-08-12 | Modernatx, Inc. | Methods and apparatus for filtration |
| MX2019004499A (es) * | 2016-10-17 | 2019-11-18 | Janssen Pharmaceuticals Inc Star | Sistemas de replicón de virus recombinante y usos de estos. |
| AU2017372731B2 (en) | 2016-12-05 | 2024-05-23 | Janssen Pharmaceuticals, Inc. | Compositions and methods for enhancing gene expression |
| JP2020518648A (ja) | 2017-05-08 | 2020-06-25 | グリットストーン オンコロジー インコーポレイテッド | アルファウイルス新生抗原ベクター |
| US20200283497A1 (en) * | 2017-09-13 | 2020-09-10 | Biontech Cell & Gene Therapies Gmbh | Rna replicon for expressing at cell receptor or an artificial t cell receptor |
| CA3075549A1 (en) * | 2017-09-13 | 2019-03-21 | Biontech Rna Pharmaceuticals Gmbh | Rna replicon for reprogramming somatic cells |
| CA3080427A1 (en) | 2017-11-06 | 2019-05-09 | Intervet International B.V. | Feline leukemia virus vaccine |
| WO2019086645A1 (en) | 2017-11-06 | 2019-05-09 | Intervet International B.V. | Rabies virus vaccine |
| US11167027B2 (en) | 2017-11-06 | 2021-11-09 | Intervet Inc. | Multivalent feline vaccine |
| EP3706788A1 (en) | 2017-11-06 | 2020-09-16 | Intervet International B.V. | Feline leukemia virus vaccine |
| BR112020011041A2 (pt) | 2017-12-04 | 2020-11-17 | Intervet International B.V. | vacina contra a doença de lyme canina |
| WO2019110481A1 (en) | 2017-12-04 | 2019-06-13 | Intervet International B.V. | Vaccination with replicon particles and oil adjuvant |
| JP7374893B2 (ja) | 2017-12-08 | 2023-11-07 | インターベット インターナショナル ベー． フェー． | ネコカリシウイルスワクチン |
| JP7427585B2 (ja) | 2017-12-15 | 2024-02-05 | インターベット インターナショナル ベー． フェー． | 多価ネコワクチン |
| CN118976103A (zh) | 2017-12-18 | 2024-11-19 | 英特维特国际股份有限公司 | 猪甲型流感病毒疫苗 |
| US11020476B2 (en) | 2017-12-19 | 2021-06-01 | Janssen Sciences Ireland Unlimited Company | Methods and compositions for inducing an immune response against Hepatitis B Virus (HBV) |
| EA202091513A1 (ru) | 2017-12-19 | 2020-09-09 | Янссен Сайенсиз Айрлэнд Анлимитед Компани | Вакцины против вируса гепатита b (hbv) и их применение |
| US11389531B2 (en) | 2017-12-19 | 2022-07-19 | Janssen Sciences Ireland Unlimited Company | Methods and apparatus for the delivery of hepatitis B virus (HBV) vaccines |
| SG11202005792RA (en) | 2017-12-20 | 2020-07-29 | Vlp Therapeutics Llc | Alphavirus replicon particle |
| CA3089024A1 (en) | 2018-01-19 | 2019-07-25 | Janssen Pharmaceuticals, Inc. | Induce and enhance immune responses using recombinant replicon systems |
| BR112021006614A2 (pt) | 2018-10-08 | 2021-07-20 | Janssen Pharmaceuticals, Inc. | replicons com base em alfavírus para administração de bioterápicos |
| CN113194989B (zh) | 2018-12-20 | 2024-01-30 | 英特维特国际股份有限公司 | 初免-强化免疫接种方案 |
| AU2020282369A1 (en) | 2019-05-30 | 2022-01-20 | Seattle Project Corp. | Modified adenoviruses |
| US11759515B2 (en) | 2020-03-09 | 2023-09-19 | Arcturus Therapeutics, Inc. | Compositions and methods for inducing immune responses |
| CN115867658A (zh) | 2020-04-17 | 2023-03-28 | Vlp治疗公司 | 冠状病毒疫苗 |
| AU2021264216A1 (en) | 2020-04-30 | 2022-11-10 | Vlp Therapeutics, Inc. | Cytokine immunotherapy |
| EP4149532A1 (en) | 2020-05-11 | 2023-03-22 | Intervet International B.V. | Feline severe acute respiratory syndrome coronavirus 2 vaccine |
| BR112022025678A2 (pt) | 2020-06-19 | 2023-01-17 | Intervet Int Bv | Vacina contra o vírus da influenza a suína compreendendo duas partículas de replicon de rna distintas |
| US20230265130A1 (en) | 2020-06-19 | 2023-08-24 | Intervet Inc. | Swine influenza a virus vaccine comprising a nucleic acid construct having a specific order of genes |
| CN115836082A (zh) | 2020-06-19 | 2023-03-21 | 英特维特国际股份有限公司 | 包含编码特定病毒谱系抗原的核酸构建体的甲型猪流感病毒疫苗 |
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| WO2022032196A2 (en) | 2020-08-06 | 2022-02-10 | Gritstone Bio, Inc. | Multiepitope vaccine cassettes |
| EP4210740A1 (en) | 2020-09-07 | 2023-07-19 | Intervet International B.V. | Ha stem vaccine for ha antibody-positive targets |
| EP4243864A1 (en) | 2020-11-12 | 2023-09-20 | Intervet International B.V. | Recombinant vectors encoding chimeric coronavirus spike proteins and use thereof |
| US20250281597A1 (en) | 2021-10-25 | 2025-09-11 | Intervet Inc. | A vaccine for the protection of piglets against swine influenza a virus infection |
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- 2008-06-20 EP EP15173487.8A patent/EP2947149B1/en active Active
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- 2008-06-20 CN CN2008801036605A patent/CN101802199B/zh active Active
- 2008-06-20 DK DK08825920.5T patent/DK2183368T3/en active
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2008156829A3 (en) | 2009-03-12 |
| DK2947149T3 (en) | 2018-06-06 |
| AU2008266807B2 (en) | 2012-08-16 |
| US20090075384A1 (en) | 2009-03-19 |
| JP5995926B2 (ja) | 2016-09-21 |
| CA2689588C (en) | 2016-08-23 |
| PL2183368T3 (pl) | 2016-12-30 |
| ES2670813T3 (es) | 2018-06-01 |
| JP2010530245A (ja) | 2010-09-09 |
| WO2008156829A2 (en) | 2008-12-24 |
| US8460913B2 (en) | 2013-06-11 |
| CN101802199B (zh) | 2012-08-22 |
| US20100183665A1 (en) | 2010-07-22 |
| EP2947149A1 (en) | 2015-11-25 |
| NZ582495A (en) | 2012-05-25 |
| EP2947149B1 (en) | 2018-02-28 |
| HK1217216A1 (en) | 2016-12-30 |
| DK2183368T3 (en) | 2016-09-05 |
| CA2689588A1 (en) | 2008-12-24 |
| CN101802199A (zh) | 2010-08-11 |
| JP2014230544A (ja) | 2014-12-11 |
| EP2183368A4 (en) | 2011-04-13 |
| US7850977B2 (en) | 2010-12-14 |
| JP2016198114A (ja) | 2016-12-01 |
| EP2183368B1 (en) | 2016-08-10 |
| IL202720A0 (en) | 2011-08-01 |
| ZA200909080B (en) | 2010-09-29 |
| ES2588906T3 (es) | 2016-11-07 |
| AU2008266807A1 (en) | 2008-12-24 |
| EP2183368A2 (en) | 2010-05-12 |
| JP5602624B2 (ja) | 2014-10-08 |
| IL202720A (en) | 2013-10-31 |
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