PL2947149T3 - Kasety bez promotora do ekspresji alfawirusowych białek strukturalnych - Google Patents
Kasety bez promotora do ekspresji alfawirusowych białek strukturalnychInfo
- Publication number
- PL2947149T3 PL2947149T3 PL15173487T PL15173487T PL2947149T3 PL 2947149 T3 PL2947149 T3 PL 2947149T3 PL 15173487 T PL15173487 T PL 15173487T PL 15173487 T PL15173487 T PL 15173487T PL 2947149 T3 PL2947149 T3 PL 2947149T3
- Authority
- PL
- Poland
- Prior art keywords
- vaccination
- alphavirus replicon
- replicon particles
- particles
- alphavirus
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/275—Poxviridae, e.g. avipoxvirus
- A61K39/285—Vaccinia virus or variola virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36141—Use of virus, viral particle or viral elements as a vector
- C12N2770/36143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93663707P | 2007-06-21 | 2007-06-21 | |
| EP15173487.8A EP2947149B1 (en) | 2007-06-21 | 2008-06-20 | Alphavirus replicon particles for use in vaccination |
| EP08825920.5A EP2183368B1 (en) | 2007-06-21 | 2008-06-20 | Promoterless cassettes for expression of alphavirus structural proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2947149T3 true PL2947149T3 (pl) | 2018-09-28 |
Family
ID=40156867
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL08825920.5T PL2183368T3 (pl) | 2007-06-21 | 2008-06-20 | Kasety bez promotora do ekspresji alfawirusowych białek strukturalnych |
| PL15173487T PL2947149T3 (pl) | 2007-06-21 | 2008-06-20 | Kasety bez promotora do ekspresji alfawirusowych białek strukturalnych |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL08825920.5T PL2183368T3 (pl) | 2007-06-21 | 2008-06-20 | Kasety bez promotora do ekspresji alfawirusowych białek strukturalnych |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US7850977B2 (pl) |
| EP (2) | EP2183368B1 (pl) |
| JP (3) | JP5602624B2 (pl) |
| CN (1) | CN101802199B (pl) |
| AU (1) | AU2008266807B2 (pl) |
| CA (1) | CA2689588C (pl) |
| DK (2) | DK2947149T3 (pl) |
| ES (2) | ES2670813T3 (pl) |
| HK (1) | HK1217216A1 (pl) |
| IL (1) | IL202720A (pl) |
| NZ (1) | NZ582495A (pl) |
| PL (2) | PL2183368T3 (pl) |
| WO (1) | WO2008156829A2 (pl) |
| ZA (1) | ZA200909080B (pl) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2689588C (en) * | 2007-06-21 | 2016-08-23 | Alphavax, Inc. | Promoterless cassettes for expression of alphavirus structural proteins |
| ES2525707T3 (es) | 2008-12-01 | 2014-12-29 | Alphavax, Inc. | Uso de microRNAs para el control de ácidos nucleicos colaboradores de virus |
| AU2010234362B2 (en) | 2009-04-08 | 2015-11-26 | Alphavax, Inc. | Alphavirus replicon particles expressing TRP2 |
| US20130171241A1 (en) | 2010-07-06 | 2013-07-04 | Novartis Ag | Liposomes with lipids having an advantageous pka-value for rna delivery |
| DK2591114T3 (en) | 2010-07-06 | 2016-08-29 | Glaxosmithkline Biologicals Sa | Immunization of large mammals with low doses of RNA |
| LT3243526T (lt) | 2010-07-06 | 2020-02-10 | Glaxosmithkline Biologicals S.A. | Rnr pristatymas, skirtas keleto imuninio atsako paleidimui |
| ES2918649T3 (es) | 2010-08-31 | 2022-07-19 | Glaxosmithkline Biologicals Sa | Liposomas pegilados para el suministro de ARN que codifica un inmunógeno |
| BR112013008700B8 (pt) | 2010-10-11 | 2022-10-04 | Novartis Ag | Molécula de rna auto-replicante, partícula de replicon de alfavírus, composição, molécula de dna recombinante, uso da molécula de rna auto-replicante |
| EP2691101A2 (en) | 2011-03-31 | 2014-02-05 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
| WO2013006838A1 (en) | 2011-07-06 | 2013-01-10 | Novartis Ag | Immunogenic combination compositions and uses thereof |
| BE1023557B1 (fr) | 2014-02-10 | 2017-05-03 | Univercells Sa | Systeme, appareil et procede pour la production de biomolecules |
| BR112018014109A2 (pt) | 2016-01-11 | 2018-12-11 | Verndari Inc | composições de microagulhas e métodos de uso das mesmas |
| WO2017162266A1 (en) | 2016-03-21 | 2017-09-28 | Biontech Rna Pharmaceuticals Gmbh | Rna replicon for versatile and efficient gene expression |
| WO2017162265A1 (en) * | 2016-03-21 | 2017-09-28 | Biontech Rna Pharmaceuticals Gmbh | Trans-replicating rna |
| JP7250520B2 (ja) | 2016-04-13 | 2023-04-03 | ヤンセン ファーマシューティカルズ，インコーポレーテッド | 組換えアルテリウイルスレプリコン系およびその使用 |
| CN110073002A (zh) | 2016-10-17 | 2019-07-30 | 合成基因组公司 | 重组病毒复制子体系及其用途 |
| WO2018106615A2 (en) * | 2016-12-05 | 2018-06-14 | Synthetic Genomics, Inc. | Compositions and methods for enhancing gene expression |
| TW202333779A (zh) | 2017-05-08 | 2023-09-01 | 美商磨石生物公司 | 阿爾法病毒新抗原載體 |
| WO2019053056A1 (en) * | 2017-09-13 | 2019-03-21 | Biontech Cell & Gene Therapies Gmbh | RNA REPLICON FOR EXPRESSING A T CELL RECEPTOR OR ARTIFICIAL LYMPHOCYTIC T CELL RECEPTOR |
| AU2018333503A1 (en) * | 2017-09-13 | 2020-02-27 | BioNTech SE | RNA replicon for reprogramming somatic cells |
| EP3706790A1 (en) | 2017-11-06 | 2020-09-16 | Intervet International B.V. | Multivalent feline vaccine |
| CN111315409A (zh) | 2017-11-06 | 2020-06-19 | 英特维特国际股份有限公司 | 狂犬病毒疫苗 |
| WO2019110213A1 (en) | 2017-12-08 | 2019-06-13 | Intervet International B.V. | Feline calicivirus vaccine |
| US11167027B2 (en) | 2017-11-06 | 2021-11-09 | Intervet Inc. | Multivalent feline vaccine |
| JP2021501761A (ja) | 2017-11-06 | 2021-01-21 | インターベット インターナショナル ベー． フェー． | ネコ白血病ウイルスワクチン |
| CA3084042A1 (en) | 2017-12-04 | 2019-06-13 | Intervet International B.V. | Vaccination with replicon particles and oil adjuvant |
| WO2019110486A1 (en) | 2017-12-04 | 2019-06-13 | Intervet International B.V. | Canine lyme disease vaccine |
| AU2018383915B9 (en) | 2017-12-15 | 2023-06-01 | Intervet International B.V. | Multivalent feline vaccine |
| US20200330585A1 (en) | 2017-12-18 | 2020-10-22 | Intervet Inc. | Swine influenza a virus vaccine |
| EA202091513A1 (ru) | 2017-12-19 | 2020-09-09 | Янссен Сайенсиз Айрлэнд Анлимитед Компани | Вакцины против вируса гепатита b (hbv) и их применение |
| US11389531B2 (en) | 2017-12-19 | 2022-07-19 | Janssen Sciences Ireland Unlimited Company | Methods and apparatus for the delivery of hepatitis B virus (HBV) vaccines |
| EA202091516A1 (ru) | 2017-12-19 | 2020-11-03 | Янссен Сайенсиз Айрлэнд Анлимитед Компани | Способы и композиции для индукции иммунного ответа против вируса гепатита b (hbv) |
| US11083786B2 (en) | 2018-01-19 | 2021-08-10 | Janssen Pharmaceuticals, Inc. | Induce and enhance immune responses using recombinant replicon systems |
| US20220023414A1 (en) | 2018-12-20 | 2022-01-27 | Intervet Inc. | Prime-Boost Vaccination Regimen |
| BR122024002387A2 (pt) | 2019-05-30 | 2024-03-12 | Gritstone Bio, Inc. | Vetores de adenovírus, composição farmacêutica, sequência de nucleotídeo isolada, célula isolada, vetor, kit, usos de um vetor, método para fabricar o vetor, métodos para produzir um vírus e vetor viral |
| EP4149532A1 (en) | 2020-05-11 | 2023-03-22 | Intervet International B.V. | Feline severe acute respiratory syndrome coronavirus 2 vaccine |
| JP2023530134A (ja) | 2020-06-19 | 2023-07-13 | インターベット インターナショナル ベー． フェー． | ウイルスの別々のノイラミニダーゼ抗原をエンコードする第１、第２および第３の核酸配列を含む核酸構築物を含むブタインフルエンザａウイルスワクチン |
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| CA3190070A1 (en) | 2020-09-07 | 2022-03-10 | Martijn Alexander LANGEREIS | Ha stem vaccine for ha antibody-positive targets |
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| WO2023072805A1 (en) | 2021-10-25 | 2023-05-04 | Intervet International B.V. | A vaccine for the protection of piglets against swine influenza a virus infection |
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- 2008-06-20 CA CA2689588A patent/CA2689588C/en active Active
- 2008-06-20 EP EP08825920.5A patent/EP2183368B1/en active Active
- 2008-06-20 PL PL08825920.5T patent/PL2183368T3/pl unknown
- 2008-06-20 DK DK15173487.8T patent/DK2947149T3/en active
- 2008-06-20 AU AU2008266807A patent/AU2008266807B2/en active Active
- 2008-06-20 EP EP15173487.8A patent/EP2947149B1/en active Active
- 2008-06-20 ES ES15173487.8T patent/ES2670813T3/es active Active
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- 2008-06-20 JP JP2010513254A patent/JP5602624B2/ja active Active
- 2008-06-20 CN CN2008801036605A patent/CN101802199B/zh active Active
- 2008-06-20 US US12/665,497 patent/US8460913B2/en active Active
- 2008-06-20 PL PL15173487T patent/PL2947149T3/pl unknown
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Also Published As
| Publication number | Publication date |
|---|---|
| IL202720A0 (en) | 2011-08-01 |
| CA2689588A1 (en) | 2008-12-24 |
| DK2183368T3 (en) | 2016-09-05 |
| HK1217216A1 (zh) | 2016-12-30 |
| ZA200909080B (en) | 2010-09-29 |
| CA2689588C (en) | 2016-08-23 |
| US20100183665A1 (en) | 2010-07-22 |
| EP2947149B1 (en) | 2018-02-28 |
| PL2183368T3 (pl) | 2016-12-30 |
| AU2008266807A1 (en) | 2008-12-24 |
| DK2947149T3 (en) | 2018-06-06 |
| JP5602624B2 (ja) | 2014-10-08 |
| US7850977B2 (en) | 2010-12-14 |
| WO2008156829A3 (en) | 2009-03-12 |
| EP2947149A1 (en) | 2015-11-25 |
| US20090075384A1 (en) | 2009-03-19 |
| WO2008156829A2 (en) | 2008-12-24 |
| ES2670813T3 (es) | 2018-06-01 |
| ES2588906T3 (es) | 2016-11-07 |
| US8460913B2 (en) | 2013-06-11 |
| EP2183368B1 (en) | 2016-08-10 |
| AU2008266807B2 (en) | 2012-08-16 |
| EP2183368A4 (en) | 2011-04-13 |
| JP2010530245A (ja) | 2010-09-09 |
| NZ582495A (en) | 2012-05-25 |
| JP2014230544A (ja) | 2014-12-11 |
| CN101802199B (zh) | 2012-08-22 |
| IL202720A (en) | 2013-10-31 |
| CN101802199A (zh) | 2010-08-11 |
| EP2183368A2 (en) | 2010-05-12 |
| JP5995926B2 (ja) | 2016-09-21 |
| JP2016198114A (ja) | 2016-12-01 |
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