DE68912478T2 - Rekombinantes Marek-Krankheitsvirus, Verfahren zu seiner Herstellung, und Vakzine. - Google Patents

Rekombinantes Marek-Krankheitsvirus, Verfahren zu seiner Herstellung, und Vakzine.

Info

Publication number
DE68912478T2
DE68912478T2 DE89116679T DE68912478T DE68912478T2 DE 68912478 T2 DE68912478 T2 DE 68912478T2 DE 89116679 T DE89116679 T DE 89116679T DE 68912478 T DE68912478 T DE 68912478T DE 68912478 T2 DE68912478 T2 DE 68912478T2
Authority
DE
Germany
Prior art keywords
virus
fragment
marek
disease virus
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE89116679T
Other languages
English (en)
Other versions
DE68912478D1 (de
Inventor
Masashi Sakaguchi
Hiroaki Maeda
Michitaka Yamamoto
Junichi Higashimachi Miyazaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chemo Sero Therapeutic Research Institute Kaketsuken
Original Assignee
Chemo Sero Therapeutic Research Institute Kaketsuken
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Sero Therapeutic Research Institute Kaketsuken filed Critical Chemo Sero Therapeutic Research Institute Kaketsuken
Publication of DE68912478D1 publication Critical patent/DE68912478D1/de
Application granted granted Critical
Publication of DE68912478T2 publication Critical patent/DE68912478T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A61K39/255—Marek's disease virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE89116679T 1988-09-10 1989-09-08 Rekombinantes Marek-Krankheitsvirus, Verfahren zu seiner Herstellung, und Vakzine. Expired - Lifetime DE68912478T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63226960A JP2583115B2 (ja) 1988-09-10 1988-09-10 組換えマレック病ウイルスおよびその製法

Publications (2)

Publication Number Publication Date
DE68912478D1 DE68912478D1 (de) 1994-03-03
DE68912478T2 true DE68912478T2 (de) 1994-05-11

Family

ID=16853319

Family Applications (1)

Application Number Title Priority Date Filing Date
DE89116679T Expired - Lifetime DE68912478T2 (de) 1988-09-10 1989-09-08 Rekombinantes Marek-Krankheitsvirus, Verfahren zu seiner Herstellung, und Vakzine.

Country Status (7)

Country Link
US (1) US5171677A (de)
EP (1) EP0361182B1 (de)
JP (1) JP2583115B2 (de)
AT (1) ATE100495T1 (de)
CA (1) CA1339774C (de)
DE (1) DE68912478T2 (de)
ES (1) ES2061850T3 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4634636A (en) * 1983-12-13 1987-01-06 Asahi Kasei Kogyo Kabushiki Kaisha Polyacetylene composite
US5965138A (en) * 1985-09-06 1999-10-12 Syntro Corporation Recombinant chimeric virus and uses thereof
US5928648A (en) * 1985-09-06 1999-07-27 Syntro Corporation Recombinant herpesvirus of turkeys and uses thereof
US5961982A (en) * 1985-09-06 1999-10-05 Syntro Corporation Recombinant herpesvirus of turkeys and uses thereof
NL9001828A (nl) * 1990-08-15 1992-03-02 Centraal Diergeneeskundig Inst Werkwijze voor het wijzigen van het cel-, weefsel- of gastheertropisme van een microoerganisme; aldus verkregen gerecombineerd microorganisme en toepassing daarvan in de geneeskunde en diergeneeskunde.
AU657144B2 (en) * 1991-07-09 1995-03-02 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Recombinant Marek's disease virus, process for preparing the same and vaccine containing the same
US5853733A (en) * 1993-02-26 1998-12-29 Syntro Corporation Recombinant herpesvirus of turkeys and uses thereof
EP0745127A4 (de) * 1994-01-11 1999-10-20 Cornell Res Foundation Inc Die kontrolle über marekskrankheit durch verhinderung der latenz und der entwicklung von tumorzellen
FR2728795B1 (fr) * 1994-12-30 1997-03-21 Rhone Merieux Vaccin vivant recombinant aviaire, utilisant comme vecteur un virus herpes aviaire
JPH08322559A (ja) * 1995-06-02 1996-12-10 Chemo Sero Therapeut Res Inst ｇＢ遺伝子プロモーターを用いた組換えヘルペスウイルス

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US128836A (en) * 1872-07-09 Improvement in draught-regulators
EP0231209B1 (de) * 1985-07-29 1991-02-06 The Upjohn Company Virus-impfstoff
AU623333B2 (en) * 1986-01-27 1992-05-14 Syntro Corporation Attenuated herpesviruses, herpesviruses which include foreign dna encoding an amino acid sequence and vaccine containing same
AU619181B2 (en) * 1987-03-19 1992-01-23 Synergen, Inc. Viral vector system for the introduction of foreign dna expression products into gallinaceous birds
CA1337120C (en) * 1987-07-27 1995-09-26 Mark D. Cochran Attenuated herpesviruses, herpesviruses which include foreign dna encoding an amino acid sequence and vaccines containing same
JP2779447B2 (ja) * 1988-03-20 1998-07-23 財団法人阪大微生物病研究会 弱毒マレック病ウイルス・ベクターを用いる組換え遺伝子作成法、及び該ウイルスの組換え体

Also Published As

Publication number Publication date
JPH0276578A (ja) 1990-03-15
ATE100495T1 (de) 1994-02-15
US5171677A (en) 1992-12-15
ES2061850T3 (es) 1994-12-16
EP0361182B1 (de) 1994-01-19
DE68912478D1 (de) 1994-03-03
JP2583115B2 (ja) 1997-02-19
CA1339774C (en) 1998-03-24
EP0361182A1 (de) 1990-04-04

Similar Documents

Publication Publication Date Title
KR910012233A (ko) 칠면조의 재조합 포진바이러스와 그것에서 유도한 생존상태의 벡터 백신류
DE69737886D1 (de) Infektioese rna virus-klone, vakzine und davon abgeleitete diagnostische assays
CA2196555A1 (en) Vr-2332 viral nucleotide sequence and methods of use
ATE78293T1 (de) Verfahren zur herstellung eines rekombinanten baculovirus-expressionsvektors.
DE69505493T2 (de) Wirt-vektor system zur anwendung in gentherapie
MXPA02005525A (es) Clones infecciosos.
DE68912478D1 (de) Rekombinantes Marek-Krankheitsvirus, Verfahren zu seiner Herstellung, und Vakzine.
DE3855122D1 (de) Artifizielles Gen, das für humane Serumalbumine kodiert, seine Verwendung und Verfahren zu seiner Herstellung
ATE188739T1 (de) Klonierung hühner-anaemia-virus-dna
EP0424044A1 (de) Rinderwachstumshormone exprimierende Transgen-Hühner
EP0294469A4 (de) Impfstoffe und diagnosetest für haemophilus influenzae.
DE69233004D1 (de) Rekombinanter Virus der Marek-Krankheit, Verfahren zur Herstellung dieses Viruses und diesen enthaltender Impfstoff
JPH08508410A (ja) 組換えトリアデノウイルスベクター
EP0424027A1 (de) Vektoren zur Erzeugung von Transgen-Hühnern
NZ242707A (en) Nucleotide sequence and polypeptide of mareks disease virus and vaccine containing the polypeptide
KR930701588A (ko) 재조합 구두 바이러스 백신
DE69535091D1 (en) Humane prostacyclinsynthase
KR960705047A (ko) 신규 단백질/폴리펩티드와 동시트랜스펙션 플라스미드 및 생조환형 담체
EP0496787A4 (en) Novel infectious bursal disease virus
RU98116217A (ru) Способ получения белка с использованием трансляционной системы митохондрий
WO1997027742B1 (en) Method of protein production using mitochondrial translation system
Morgan et al. Recombinant vaccine against Marek's disease
TH25170A (th) รีคอมบิแนนท์วัคซีนของนกชนิดที่มีชีวิตโดยใช้เฮอร์ปีส์ไวรัสของนกเป็นเวกเตอร์

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee