FR2725213B1 - Vecteurs viraux et utilisation en therapie genique - Google Patents
Vecteurs viraux et utilisation en therapie geniqueInfo
- Publication number
- FR2725213B1 FR2725213B1 FR9411846A FR9411846A FR2725213B1 FR 2725213 B1 FR2725213 B1 FR 2725213B1 FR 9411846 A FR9411846 A FR 9411846A FR 9411846 A FR9411846 A FR 9411846A FR 2725213 B1 FR2725213 B1 FR 2725213B1
- Authority
- FR
- France
- Prior art keywords
- gene therapy
- viral vectors
- viral
- vectors
- therapy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/55—IL-2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/15—Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/60—Vector systems having a special element relevant for transcription from viruses
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9411846A FR2725213B1 (fr) | 1994-10-04 | 1994-10-04 | Vecteurs viraux et utilisation en therapie genique |
AU36114/95A AU714867B2 (en) | 1994-10-04 | 1995-10-02 | Adenovirus-derived viral vectors having two therapeutic genes: suicide and immunopotentiating |
JP8511469A JPH10506289A (ja) | 1994-10-04 | 1995-10-02 | 2の治療的遺伝子:自殺性および免疫刺激性遺伝子を含むアデノウイルス |
EP95933464A EP0784691A1 (fr) | 1994-10-04 | 1995-10-02 | Adenoviraux comprenant deux genes therapeutiques: suicide et immunostimulant |
CA002200629A CA2200629A1 (fr) | 1994-10-04 | 1995-10-02 | Adenoviraux comprenant deux genes therapeutiques: suicide et immunostimulant |
PCT/FR1995/001274 WO1996010642A1 (fr) | 1994-10-04 | 1995-10-02 | Adenoviraux comprenant deux genes therapeutiques: suicide et immunostimulant |
MX9702078A MX9702078A (es) | 1994-10-04 | 1995-10-02 | Adenovirus que comprenden dos genes terapeuticos: suicida e inmunoestimulante. |
NO19971521A NO319893B1 (no) | 1994-10-04 | 1997-04-03 | Defektiv, rekombinert adenovirus og farmasoytisk preparat omfattende denne. |
FI971377A FI971377A0 (fi) | 1994-10-04 | 1997-04-03 | Adenovirusperäisiä virusvektoreita, joissa on kaksi terapeuttista geeniä: itsemurha- ja immuunistimuloiva geeni |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9411846A FR2725213B1 (fr) | 1994-10-04 | 1994-10-04 | Vecteurs viraux et utilisation en therapie genique |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2725213A1 FR2725213A1 (fr) | 1996-04-05 |
FR2725213B1 true FR2725213B1 (fr) | 1996-11-08 |
Family
ID=9467551
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR9411846A Expired - Fee Related FR2725213B1 (fr) | 1994-10-04 | 1994-10-04 | Vecteurs viraux et utilisation en therapie genique |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0784691A1 (fr) |
JP (1) | JPH10506289A (fr) |
AU (1) | AU714867B2 (fr) |
CA (1) | CA2200629A1 (fr) |
FI (1) | FI971377A0 (fr) |
FR (1) | FR2725213B1 (fr) |
MX (1) | MX9702078A (fr) |
NO (1) | NO319893B1 (fr) |
WO (1) | WO1996010642A1 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0695347B1 (fr) * | 1993-04-20 | 2007-08-01 | Hipler Partners, Llp | Methode et materiel de traitement de patients infectes par des agents infectieux intracellulaires |
US6593456B1 (en) | 1996-11-06 | 2003-07-15 | The Regents Of The University Of California | Tumor necrosis factor receptor releasing enzyme |
JP2001515052A (ja) * | 1997-08-13 | 2001-09-18 | ザ ユーエイビー リサーチ ファンデーション | 遺伝子ベクターの局所施用によるワクチン接種 |
AUPO856097A0 (en) | 1997-08-14 | 1997-09-04 | Commonwealth Scientific And Industrial Research Organisation | Vector |
US7041654B2 (en) | 1997-10-03 | 2006-05-09 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Methods and compositions for inducing tumor-specific cytotoxicity |
US6087164A (en) * | 1997-10-03 | 2000-07-11 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Methods and compositions for inducing tumor-specific cytotoxicity |
US7569217B2 (en) | 2001-09-24 | 2009-08-04 | University Of Saskatchewan | Porcine adenovirus E1 and E4 regions |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU612983B2 (en) * | 1986-08-01 | 1991-07-25 | Australian National University, The | Recombinant vaccine |
WO1993010218A1 (fr) * | 1991-11-14 | 1993-05-27 | The United States Government As Represented By The Secretary Of The Department Of Health And Human Services | Vecteurs comprenant des genes etrangers et des marqueurs selectifs negatifs |
FR2688514A1 (fr) * | 1992-03-16 | 1993-09-17 | Centre Nat Rech Scient | Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant. |
DK0637966T3 (da) * | 1992-05-01 | 1998-05-04 | Us Health | Tumoricid terapi med "tilskuer-virkning" |
EP1024198A3 (fr) * | 1992-12-03 | 2002-05-29 | Genzyme Corporation | Vecteurs pseudo-adenoviraux pour la thérapie génique des hémophilies |
FR2704234B1 (fr) * | 1993-04-22 | 1995-07-21 | Centre Nat Rech Scient | Virus recombinants, preparation et utilisation en therapie genique. |
FR2705361B1 (fr) * | 1993-05-18 | 1995-08-04 | Centre Nat Rech Scient | Vecteurs viraux et utilisation en thérapie génique. |
FR2705686B1 (fr) * | 1993-05-28 | 1995-08-18 | Transgene Sa | Nouveaux adénovirus défectifs et lignées de complémentation correspondantes. |
DE69434486T2 (de) * | 1993-06-24 | 2006-07-06 | Advec Inc. | Adenovirus vektoren für gentherapie |
FR2707664B1 (fr) * | 1993-07-13 | 1995-09-29 | Centre Nat Rech Scient | Vecteurs viraux et utilisation en thérapie génique. |
FR2712603B1 (fr) * | 1993-11-18 | 1996-02-09 | Centre Nat Rech Scient | Virus recombinants, préparation et utilisation en thérapie génique. |
-
1994
- 1994-10-04 FR FR9411846A patent/FR2725213B1/fr not_active Expired - Fee Related
-
1995
- 1995-10-02 JP JP8511469A patent/JPH10506289A/ja active Pending
- 1995-10-02 MX MX9702078A patent/MX9702078A/es not_active Application Discontinuation
- 1995-10-02 WO PCT/FR1995/001274 patent/WO1996010642A1/fr not_active Application Discontinuation
- 1995-10-02 CA CA002200629A patent/CA2200629A1/fr not_active Abandoned
- 1995-10-02 AU AU36114/95A patent/AU714867B2/en not_active Ceased
- 1995-10-02 EP EP95933464A patent/EP0784691A1/fr not_active Withdrawn
-
1997
- 1997-04-03 NO NO19971521A patent/NO319893B1/no unknown
- 1997-04-03 FI FI971377A patent/FI971377A0/fi not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU714867B2 (en) | 2000-01-13 |
AU3611495A (en) | 1996-04-26 |
CA2200629A1 (fr) | 1996-04-11 |
MX9702078A (es) | 1997-06-28 |
FI971377A (fi) | 1997-04-03 |
WO1996010642A1 (fr) | 1996-04-11 |
JPH10506289A (ja) | 1998-06-23 |
NO971521L (no) | 1997-04-03 |
FI971377A0 (fi) | 1997-04-03 |
FR2725213A1 (fr) | 1996-04-05 |
EP0784691A1 (fr) | 1997-07-23 |
NO971521D0 (no) | 1997-04-03 |
NO319893B1 (no) | 2005-09-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CD | Change of name or company name | ||
ST | Notification of lapse |
Effective date: 20080630 |