DE69837089D1 - Behandlung der diabetes mit thiazolidindione und sulphonylurea - Google Patents

Behandlung der diabetes mit thiazolidindione und sulphonylurea

Info

Publication number
DE69837089D1
DE69837089D1 DE69837089T DE69837089T DE69837089D1 DE 69837089 D1 DE69837089 D1 DE 69837089D1 DE 69837089 T DE69837089 T DE 69837089T DE 69837089 T DE69837089 T DE 69837089T DE 69837089 D1 DE69837089 D1 DE 69837089D1
Authority
DE
Germany
Prior art keywords
thiazolideindione
sulphonylurea
diabetes
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69837089T
Other languages
English (en)
Other versions
DE69837089T2 (de
Inventor
Stephen Alistair Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26311744&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69837089(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9712854.0A external-priority patent/GB9712854D0/en
Priority claimed from GBGB9806710.1A external-priority patent/GB9806710D0/en
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of DE69837089D1 publication Critical patent/DE69837089D1/de
Application granted granted Critical
Publication of DE69837089T2 publication Critical patent/DE69837089T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/145Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/64Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
DE69837089T 1997-06-18 1998-06-15 Behandlung der diabetes mit thiazolidindion und sulfonylharnstoff Expired - Lifetime DE69837089T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9712854 1997-06-18
GBGB9712854.0A GB9712854D0 (en) 1997-06-18 1997-06-18 Novel method of treatment
GBGB9806710.1A GB9806710D0 (en) 1998-03-27 1998-03-27 Novel method
GB9806710 1998-03-27
PCT/EP1998/003688 WO1998057649A1 (en) 1997-06-18 1998-06-15 Treatment of diabetes with thiazolidinedione and sulphonylurea

Publications (2)

Publication Number Publication Date
DE69837089D1 true DE69837089D1 (de) 2007-03-29
DE69837089T2 DE69837089T2 (de) 2007-06-21

Family

ID=26311744

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69837089T Expired - Lifetime DE69837089T2 (de) 1997-06-18 1998-06-15 Behandlung der diabetes mit thiazolidindion und sulfonylharnstoff

Country Status (34)

Country Link
EP (3) EP1671637A3 (de)
JP (1) JP2001523270A (de)
KR (3) KR20070011651A (de)
CN (1) CN1168451C (de)
AP (1) AP1600A (de)
AR (2) AR008025A1 (de)
AT (1) ATE353654T1 (de)
AU (1) AU8539298A (de)
BG (2) BG64817B1 (de)
BR (1) BR9810142A (de)
CA (1) CA2294385C (de)
CO (1) CO4940457A1 (de)
CZ (1) CZ299310B6 (de)
DE (1) DE69837089T2 (de)
DZ (1) DZ2522A1 (de)
EA (1) EA003025B1 (de)
ES (1) ES2283064T3 (de)
HK (1) HK1028200A1 (de)
ID (1) ID24065A (de)
IL (1) IL133137A (de)
IN (1) IN189319B (de)
MA (1) MA24571A1 (de)
MY (1) MY125855A (de)
NO (3) NO326263B1 (de)
NZ (1) NZ501163A (de)
OA (1) OA11510A (de)
PE (1) PE108199A1 (de)
PL (2) PL337510A1 (de)
SK (1) SK286028B6 (de)
TR (1) TR199903096T2 (de)
TW (1) TW542717B (de)
UA (1) UA67743C2 (de)
UY (1) UY25048A1 (de)
WO (1) WO1998057649A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9715295D0 (en) * 1997-07-18 1997-09-24 Smithkline Beecham Plc Novel method of treatment
EP1173434B1 (de) 1999-04-23 2003-08-20 SmithKline Beecham plc Thiazolidindionderivat und seine verwendung als antidiabetikum
WO2001032184A2 (en) * 1999-11-01 2001-05-10 Wisconsin Alumni Research Foundation Abc1 modulation for the modulation of cholesterol transport
US7964216B2 (en) 2001-01-12 2011-06-21 Sun Pharma Advanced Research Company Limited Spaced drug delivery system
KR100698595B1 (ko) * 2003-09-29 2007-03-21 보령제약 주식회사 무정형 또는 준결정형 글리메피리드, 이의 제조방법 및 무정형 또는 준결정형 글리메피리드를 포함하는 약학적조성물
US7700128B2 (en) * 2003-10-31 2010-04-20 Takeda Pharmaceutical Company Limited Solid preparation comprising an insulin sensitizer, an insulin secretagogue and a polyoxyethylene sorbitan fatty acid ester
WO2007072992A2 (en) 2005-12-22 2007-06-28 Takeda Pharmaceutical Company Limited Solid preparation containing an insulin sensitizer
CN104158867B (zh) * 2014-08-06 2017-05-17 电子科技大学 一种基于wave协议的信息多跳转发方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
JPS5697277A (en) 1980-01-07 1981-08-05 Takeda Chem Ind Ltd Thiazolidine derivative
JPS6051189A (ja) 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
US4582839A (en) 1984-03-21 1986-04-15 Takeda Chemical Industries, Ltd. 2,4-thiazolidinediones
CN1003445B (zh) 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物,其制备方法和用途
DK173350B1 (da) 1985-02-26 2000-08-07 Sankyo Co Thiazolidinderivater, deres fremstilling og farmaceutisk paæparat indeholdende dem
JPH06779B2 (ja) 1985-06-10 1994-01-05 武田薬品工業株式会社 チアゾリジオン誘導体およびそれを含んでなる医薬組成物
US4812570A (en) 1986-07-24 1989-03-14 Takeda Chemical Industries, Ltd. Method for producing thiazolidinedione derivatives
EP0842925A1 (de) 1987-09-04 1998-05-20 Beecham Group Plc Substituierte Thiazolidindionderivate
US4791125A (en) 1987-12-02 1988-12-13 Pfizer Inc. Thiazolidinediones as hypoglycemic and anti-atherosclerosis agents
WO1989008650A1 (en) 1988-03-08 1989-09-21 Pfizer Inc. Thiazolidinedione hypoglycemic agents
MX15171A (es) 1988-03-08 1993-05-01 Pfizer Derivados de tiazolidinodiona hipoglicemicos
WO1991007107A1 (en) 1989-11-13 1991-05-30 Pfizer Inc. Oxazolidinedione hypoglycemic agents
US5089514A (en) 1990-06-14 1992-02-18 Pfizer Inc. 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents
KR930701436A (ko) 1990-07-03 1993-06-11 오노다 마사아이 비스헤테로환 화합물
HUT70153A (en) 1990-08-23 1995-09-28 Pfizer Hypoglycemic hydroxyurea derivatives
JPH04210683A (ja) 1990-12-06 1992-07-31 Terumo Corp チアゾリジン−2,4−ジオン誘導体およびこれを含有する糖尿病合併症治療薬
HUT68370A (en) 1991-04-11 1995-06-28 Takeda Chemical Industries Ltd Thiazolidine derivatives, pharmaceutical compositions containing them and process for their production
US5183823A (en) 1991-04-11 1993-02-02 Takeda Chemical Industries, Ltd. Pyridine n-oxide compounds which are useful as hypoglycemic and hypolipidemic agents
TW222626B (de) 1991-07-22 1994-04-21 Pfizer
FR2680512B1 (fr) 1991-08-20 1995-01-20 Adir Nouveaux derives de 2,4-thiazolidinedione, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
WO1993003724A1 (en) * 1991-08-26 1993-03-04 The Upjohn Company Pharmaceutical composition containing 3-guanidinopropionic acid and pioglitazone glibenclamide or glimepiride
JPH05271204A (ja) 1992-03-26 1993-10-19 Japan Tobacco Inc 新規なトリアジン誘導体
US5264451A (en) 1992-04-07 1993-11-23 American Home Products Corporation Process for treating hyperglycemia using trifluoromethyl substituted 3H-pyrazol-3-ones
JPH07505647A (ja) 1992-04-10 1995-06-22 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 複素環化合物および2型糖尿病の治療におけるそれらの使用
WO1993022445A1 (en) 1992-05-05 1993-11-11 The Upjohn Company A process for producing pioglitazone metabolite
NZ253742A (en) 1992-07-03 1997-06-24 Smithkline Beecham Plc Heterocyclylaminoalkoxy substituted phenyl derivatives and pharmaceutical compositions
US5232945A (en) 1992-07-20 1993-08-03 Pfizer Inc. 3-aryl-2-hydroxypropionic acid derivatives and analogs as antihypertensives
GB9218830D0 (en) * 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
US5478852C1 (en) 1993-09-15 2001-03-13 Sankyo Co Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of impaired glucose tolerance in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus
TW438587B (en) * 1995-06-20 2001-06-07 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes
US5859037A (en) * 1997-02-19 1999-01-12 Warner-Lambert Company Sulfonylurea-glitazone combinations for diabetes

Also Published As

Publication number Publication date
UY25048A1 (es) 2000-09-29
KR20010013840A (ko) 2001-02-26
ATE353654T1 (de) 2007-03-15
AP1600A (en) 2006-04-28
NO20083276L (no) 2000-02-17
NO2009002I1 (no) 2009-03-02
IL133137A0 (en) 2001-03-19
HK1028200A1 (en) 2001-02-09
AR012996A1 (es) 2000-11-22
NO326263B1 (no) 2008-10-27
DZ2522A1 (fr) 2003-02-01
CN1168451C (zh) 2004-09-29
OA11510A (en) 2004-02-03
NZ501163A (en) 2002-02-01
CZ299310B6 (cs) 2008-06-18
BG64817B1 (bg) 2006-05-31
WO1998057649A1 (en) 1998-12-23
AP9901717A0 (en) 1999-12-31
CO4940457A1 (es) 2000-07-24
NO996264D0 (no) 1999-12-17
JP2001523270A (ja) 2001-11-20
CA2294385C (en) 2007-06-05
IN189319B (de) 2003-02-08
CN1260719A (zh) 2000-07-19
PL337510A1 (en) 2000-08-28
KR20080011356A (ko) 2008-02-01
EP0999845B1 (de) 2007-02-14
EP0999845A1 (de) 2000-05-17
DE69837089T2 (de) 2007-06-21
BG109397A (bg) 2006-05-31
IL133137A (en) 2004-02-08
EA003025B1 (ru) 2002-12-26
PL198018B1 (pl) 2008-05-30
TW542717B (en) 2003-07-21
MY125855A (en) 2006-08-30
SK286028B6 (sk) 2008-01-07
ID24065A (id) 2000-07-06
PE108199A1 (es) 2000-01-14
EA200000039A1 (ru) 2000-08-28
EP1671637A3 (de) 2007-12-19
NO996264L (no) 2000-02-17
SK179199A3 (en) 2000-11-07
MA24571A1 (fr) 1998-12-31
ES2283064T3 (es) 2007-10-16
EP1671637A2 (de) 2006-06-21
CZ9904577A3 (en) 2001-05-16
KR20070011651A (ko) 2007-01-24
BG104058A (en) 2000-10-31
UA67743C2 (uk) 2004-07-15
TR199903096T2 (xx) 2000-08-21
BR9810142A (pt) 2000-08-08
AR008025A1 (es) 1999-12-09
CA2294385A1 (en) 1998-12-23
EP2266576A1 (de) 2010-12-29
AU8539298A (en) 1999-01-04

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Legal Events

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8364 No opposition during term of opposition