DE69814848T2 - Untersuchung von nukleotiden in loesung mit hilfe von pna-sonden - Google Patents

Untersuchung von nukleotiden in loesung mit hilfe von pna-sonden Download PDF

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Publication number
DE69814848T2
DE69814848T2 DE69814848T DE69814848T DE69814848T2 DE 69814848 T2 DE69814848 T2 DE 69814848T2 DE 69814848 T DE69814848 T DE 69814848T DE 69814848 T DE69814848 T DE 69814848T DE 69814848 T2 DE69814848 T2 DE 69814848T2
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DE
Germany
Prior art keywords
nucleotide sequence
intensity
probe
marker
pna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69814848T
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German (de)
English (en)
Other versions
DE69814848D1 (de
Inventor
Xiao-Feng Eileen NIE
Min Yuan WU
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Ingeneus Corp
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Ingeneus Corp
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Filing date
Publication date
Priority claimed from US08/870,370 external-priority patent/US6060242A/en
Application filed by Ingeneus Corp filed Critical Ingeneus Corp
Publication of DE69814848D1 publication Critical patent/DE69814848D1/de
Application granted granted Critical
Publication of DE69814848T2 publication Critical patent/DE69814848T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69814848T 1997-02-27 1998-02-23 Untersuchung von nukleotiden in loesung mit hilfe von pna-sonden Expired - Fee Related DE69814848T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US807901 1985-12-11
US870370 1992-04-17
US80790197A 1997-02-27 1997-02-27
US08/870,370 US6060242A (en) 1997-02-27 1997-06-06 PNA diagnostic methods
PCT/IB1998/000521 WO1998038334A1 (en) 1997-02-27 1998-02-23 Assaying nucleotides in solution using pna probes

Publications (2)

Publication Number Publication Date
DE69814848D1 DE69814848D1 (de) 2003-06-26
DE69814848T2 true DE69814848T2 (de) 2004-05-06

Family

ID=27123055

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69814848T Expired - Fee Related DE69814848T2 (de) 1997-02-27 1998-02-23 Untersuchung von nukleotiden in loesung mit hilfe von pna-sonden

Country Status (13)

Country Link
EP (1) EP0975800B1 (https=)
JP (1) JP4110223B2 (https=)
AT (1) ATE241018T1 (https=)
AU (1) AU736701B2 (https=)
CA (1) CA2282704C (https=)
CY (1) CY2406B1 (https=)
DE (1) DE69814848T2 (https=)
DK (1) DK0975800T3 (https=)
ES (1) ES2202821T3 (https=)
IN (1) IN188176B (https=)
PT (1) PT975800E (https=)
TW (1) TW389791B (https=)
WO (1) WO1998038334A1 (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2255599C (en) 1996-04-25 2006-09-05 Bioarray Solutions, Llc Light-controlled electrokinetic assembly of particles near surfaces
US6046004A (en) * 1997-02-27 2000-04-04 Lorne Park Research, Inc. Solution hybridization of nucleic acids with antisense probes having modified backbones
US6251591B1 (en) * 1997-02-27 2001-06-26 Lorne Park Research, Inc. Quantitative method for detecting nucleotide concentration
WO2000034521A1 (en) * 1998-12-08 2000-06-15 Boston Probes, Inc. Methods, kits and compositions for the identification of nucleic acids electrostatically bound to matrices
ATE275640T1 (de) * 1998-12-08 2004-09-15 Boston Probes Inc Verfahren, reagentiensätze und zusammenstellungen zur erkennung von elektrostatisch an matrizen gebundene nukleinsäuren
US6656692B2 (en) * 1999-12-21 2003-12-02 Ingeneus Corporation Parallel or antiparallel, homologous or complementary binding of nucleic acids or analogues thereof to form duplex, triplex or quadruplex complexes
WO2000056937A2 (en) * 1999-03-25 2000-09-28 Hyseq, Inc. Solution-based methods and materials for sequence analysis by hybridization
US7220541B2 (en) * 2000-01-24 2007-05-22 Ingeneus, Inc. Homogeneous assay of biopolymer binding by means of multiple measurements under varied conditions
US6265170B1 (en) * 2000-01-24 2001-07-24 Ingeneus Corporation Homogenous assay of duplex of triplex hybridization by means of multiple measurements under varied conditions
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
WO2002018656A2 (en) * 2000-08-30 2002-03-07 Avi Biopharma, Inc. Method for analysis of oligonucleotide analogs
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
CA2497740C (en) 2001-10-15 2011-06-21 Bioarray Solutions, Ltd. Multiplexed analysis of polymorphic loci by probe elongation-mediated detection
US7810380B2 (en) 2003-03-25 2010-10-12 Tearlab Research, Inc. Systems and methods for collecting tear film and measuring tear film osmolarity
US7041453B2 (en) 2002-08-22 2006-05-09 Bioarray Solutions Ltd. Molecular constructs and methods of use for detection of biochemical reactions
AU2003298655A1 (en) 2002-11-15 2004-06-15 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
CA2539824C (en) 2003-09-22 2015-02-03 Xinwen Wang Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
WO2005040755A2 (en) 2003-10-20 2005-05-06 The Regents Of The University Of California Nanoscale transduction systems for detecting molecular interactions
CA2544041C (en) 2003-10-28 2015-12-08 Bioarray Solutions Ltd. Optimization of gene expression analysis using immobilized capture probes
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
ES2546743B1 (es) 2014-03-28 2016-07-07 Institut D'investigació Biomèdica De Bellvitge (Idibell) Marcadores mitocondriales de enfermedades neurodegenerativas
BR112017005121A2 (pt) 2014-09-23 2018-07-31 Tearlab Res Inc sistemas e métodos para integração de coleta de lágrima microfluídica e análise de fluxo lateral de analitos de interesse.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE88761T1 (de) * 1986-01-10 1993-05-15 Amoco Corp Kompetitiver homogener test.
CA2084405A1 (en) * 1991-04-11 1992-10-12 Chao-Huei Jeffrey Wang Detection of dna/rna by fluorescence polarization
US5539082A (en) * 1993-04-26 1996-07-23 Nielsen; Peter E. Peptide nucleic acids
DE4216949C2 (de) * 1992-05-22 1997-07-24 Christoph Prof Dr Dr Cremer Nichtenzymatisches Verfahren zur In-situ-Hybridisierung bei spezifischen Proben
DE69634696T2 (de) * 1995-10-06 2006-01-19 PerSeptive Biosystems, Inc., Framingham Verfahren und testsystem zur hybridisierungsanalyse unter verwendung von peptidnukleinsäure-sonden

Also Published As

Publication number Publication date
DE69814848D1 (de) 2003-06-26
DK0975800T3 (da) 2003-09-22
TW389791B (en) 2000-05-11
EP0975800B1 (en) 2003-05-21
AU6513598A (en) 1998-09-18
JP2001514497A (ja) 2001-09-11
CA2282704A1 (en) 1998-09-03
WO1998038334A1 (en) 1998-09-03
ES2202821T3 (es) 2004-04-01
CY2406B1 (en) 2004-09-10
ATE241018T1 (de) 2003-06-15
EP0975800A1 (en) 2000-02-02
AU736701B2 (en) 2001-08-02
JP4110223B2 (ja) 2008-07-02
IN188176B (https=) 2002-08-31
CA2282704C (en) 2007-11-13
PT975800E (pt) 2003-10-31

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