AU736701B2 - Assaying nucleotides in solution using PNA probes - Google Patents

Assaying nucleotides in solution using PNA probes Download PDF

Info

Publication number
AU736701B2
AU736701B2 AU65135/98A AU6513598A AU736701B2 AU 736701 B2 AU736701 B2 AU 736701B2 AU 65135/98 A AU65135/98 A AU 65135/98A AU 6513598 A AU6513598 A AU 6513598A AU 736701 B2 AU736701 B2 AU 736701B2
Authority
AU
Australia
Prior art keywords
nucleotide sequence
intensity
detecting
probe
marker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU65135/98A
Other languages
English (en)
Other versions
AU6513598A (en
Inventor
Eileen Xiao-Feng Nie
Yuan Min Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ingeneus Corp
Original Assignee
Lorne Park Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/870,370 external-priority patent/US6060242A/en
Application filed by Lorne Park Research Inc filed Critical Lorne Park Research Inc
Publication of AU6513598A publication Critical patent/AU6513598A/en
Application granted granted Critical
Publication of AU736701B2 publication Critical patent/AU736701B2/en
Assigned to INGENEUS CORPORATION reassignment INGENEUS CORPORATION Alteration of Name(s) in Register under S187 Assignors: LORNE PARK RESEARCH, INC.
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU65135/98A 1997-02-27 1998-02-23 Assaying nucleotides in solution using PNA probes Ceased AU736701B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US80790197A 1997-02-27 1997-02-27
US08/807901 1997-02-27
US08/870,370 US6060242A (en) 1997-02-27 1997-06-06 PNA diagnostic methods
US08/870370 1997-06-06
PCT/IB1998/000521 WO1998038334A1 (en) 1997-02-27 1998-02-23 Assaying nucleotides in solution using pna probes

Publications (2)

Publication Number Publication Date
AU6513598A AU6513598A (en) 1998-09-18
AU736701B2 true AU736701B2 (en) 2001-08-02

Family

ID=27123055

Family Applications (1)

Application Number Title Priority Date Filing Date
AU65135/98A Ceased AU736701B2 (en) 1997-02-27 1998-02-23 Assaying nucleotides in solution using PNA probes

Country Status (13)

Country Link
EP (1) EP0975800B1 (https=)
JP (1) JP4110223B2 (https=)
AT (1) ATE241018T1 (https=)
AU (1) AU736701B2 (https=)
CA (1) CA2282704C (https=)
CY (1) CY2406B1 (https=)
DE (1) DE69814848T2 (https=)
DK (1) DK0975800T3 (https=)
ES (1) ES2202821T3 (https=)
IN (1) IN188176B (https=)
PT (1) PT975800E (https=)
TW (1) TW389791B (https=)
WO (1) WO1998038334A1 (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2255599C (en) 1996-04-25 2006-09-05 Bioarray Solutions, Llc Light-controlled electrokinetic assembly of particles near surfaces
US6046004A (en) * 1997-02-27 2000-04-04 Lorne Park Research, Inc. Solution hybridization of nucleic acids with antisense probes having modified backbones
US6251591B1 (en) * 1997-02-27 2001-06-26 Lorne Park Research, Inc. Quantitative method for detecting nucleotide concentration
WO2000034521A1 (en) * 1998-12-08 2000-06-15 Boston Probes, Inc. Methods, kits and compositions for the identification of nucleic acids electrostatically bound to matrices
ATE275640T1 (de) * 1998-12-08 2004-09-15 Boston Probes Inc Verfahren, reagentiensätze und zusammenstellungen zur erkennung von elektrostatisch an matrizen gebundene nukleinsäuren
US6656692B2 (en) * 1999-12-21 2003-12-02 Ingeneus Corporation Parallel or antiparallel, homologous or complementary binding of nucleic acids or analogues thereof to form duplex, triplex or quadruplex complexes
WO2000056937A2 (en) * 1999-03-25 2000-09-28 Hyseq, Inc. Solution-based methods and materials for sequence analysis by hybridization
US7220541B2 (en) * 2000-01-24 2007-05-22 Ingeneus, Inc. Homogeneous assay of biopolymer binding by means of multiple measurements under varied conditions
US6265170B1 (en) * 2000-01-24 2001-07-24 Ingeneus Corporation Homogenous assay of duplex of triplex hybridization by means of multiple measurements under varied conditions
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
WO2002018656A2 (en) * 2000-08-30 2002-03-07 Avi Biopharma, Inc. Method for analysis of oligonucleotide analogs
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
CA2497740C (en) 2001-10-15 2011-06-21 Bioarray Solutions, Ltd. Multiplexed analysis of polymorphic loci by probe elongation-mediated detection
US7810380B2 (en) 2003-03-25 2010-10-12 Tearlab Research, Inc. Systems and methods for collecting tear film and measuring tear film osmolarity
US7041453B2 (en) 2002-08-22 2006-05-09 Bioarray Solutions Ltd. Molecular constructs and methods of use for detection of biochemical reactions
AU2003298655A1 (en) 2002-11-15 2004-06-15 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
CA2539824C (en) 2003-09-22 2015-02-03 Xinwen Wang Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
WO2005040755A2 (en) 2003-10-20 2005-05-06 The Regents Of The University Of California Nanoscale transduction systems for detecting molecular interactions
CA2544041C (en) 2003-10-28 2015-12-08 Bioarray Solutions Ltd. Optimization of gene expression analysis using immobilized capture probes
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
ES2546743B1 (es) 2014-03-28 2016-07-07 Institut D'investigació Biomèdica De Bellvitge (Idibell) Marcadores mitocondriales de enfermedades neurodegenerativas
BR112017005121A2 (pt) 2014-09-23 2018-07-31 Tearlab Res Inc sistemas e métodos para integração de coleta de lágrima microfluídica e análise de fluxo lateral de analitos de interesse.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993024652A1 (de) * 1992-05-22 1993-12-09 Cristoph Cremer Verfahren zur präparierung und hybridisierung von spezifischen proben

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE88761T1 (de) * 1986-01-10 1993-05-15 Amoco Corp Kompetitiver homogener test.
CA2084405A1 (en) * 1991-04-11 1992-10-12 Chao-Huei Jeffrey Wang Detection of dna/rna by fluorescence polarization
US5539082A (en) * 1993-04-26 1996-07-23 Nielsen; Peter E. Peptide nucleic acids
DE69634696T2 (de) * 1995-10-06 2006-01-19 PerSeptive Biosystems, Inc., Framingham Verfahren und testsystem zur hybridisierungsanalyse unter verwendung von peptidnukleinsäure-sonden

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993024652A1 (de) * 1992-05-22 1993-12-09 Cristoph Cremer Verfahren zur präparierung und hybridisierung von spezifischen proben

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CARLSSON ET AL (1996) NATURE VOL. 380, P207 *

Also Published As

Publication number Publication date
DE69814848D1 (de) 2003-06-26
DK0975800T3 (da) 2003-09-22
TW389791B (en) 2000-05-11
EP0975800B1 (en) 2003-05-21
AU6513598A (en) 1998-09-18
JP2001514497A (ja) 2001-09-11
CA2282704A1 (en) 1998-09-03
WO1998038334A1 (en) 1998-09-03
ES2202821T3 (es) 2004-04-01
DE69814848T2 (de) 2004-05-06
CY2406B1 (en) 2004-09-10
ATE241018T1 (de) 2003-06-15
EP0975800A1 (en) 2000-02-02
JP4110223B2 (ja) 2008-07-02
IN188176B (https=) 2002-08-31
CA2282704C (en) 2007-11-13
PT975800E (pt) 2003-10-31

Similar Documents

Publication Publication Date Title
US6060242A (en) PNA diagnostic methods
AU736701B2 (en) Assaying nucleotides in solution using PNA probes
AU730865B2 (en) Assaying nucleotides in solution using a fluorescent intensity quenching effect
US6046004A (en) Solution hybridization of nucleic acids with antisense probes having modified backbones
EP1078100B1 (en) Quantitative method for detecting nucleotide concentration
US6238866B1 (en) Detector for nucleic acid typing and methods of using the same
EP0843736B1 (en) Detection of mismatches by resolvase cleavage on a solid support
KR101720483B1 (ko) 뱀장어 종 판별용 펩티드핵산(pna) 프로브 세트 및 이를 이용한 뱀장어 종 판별 방법
KR101922598B1 (ko) 실시간 중합효소연쇄반응을 이용하여 rnf213 유전자의 돌연변이를 원인으로 하는 질병을 진단하기 위한 조성물 및 이의 이용
KR100617427B1 (ko) 다양한 조건하의 다중 측정에 의한 생중합체 결합의 균일분석 방법
CA1313633C (en) Purification of polymorphic components of complex genomes
WO1993018178A1 (en) DIAGNOSIS OF β-THALASSEMIA USING A MULTIPLEX AMPLIFICATION REFRACTORY MUTATION SYSTEM
Corley-Smith et al. Efficient detection of DNA polymorphisms by fluorescent RAPD analysis
JPH06261758A (ja) マラリアの検出
CN103298951B (zh) 变异型dna的检测方法
US7074567B2 (en) Assay for human DNA for gender determination

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
PC Assignment registered

Owner name: INGENEUS CORPORATION

Free format text: FORMER OWNER WAS: LORNE PARK RESEARCH, INC.