DE69732640T2 - Festphasen-peptidsynthese - Google Patents
Festphasen-peptidsynthese Download PDFInfo
- Publication number
- DE69732640T2 DE69732640T2 DE69732640T DE69732640T DE69732640T2 DE 69732640 T2 DE69732640 T2 DE 69732640T2 DE 69732640 T DE69732640 T DE 69732640T DE 69732640 T DE69732640 T DE 69732640T DE 69732640 T2 DE69732640 T2 DE 69732640T2
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- Germany
- Prior art keywords
- peptide
- acid
- protected
- sequence
- fmoc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
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- Peptides Or Proteins (AREA)
- Prostheses (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
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| DK97196 | 1996-09-09 | ||
| DK97196 | 1996-09-09 | ||
| PCT/DK1997/000375 WO1998011125A1 (en) | 1996-09-09 | 1997-09-09 | Improved solid-phase peptide synthesis and agent for use in such synthesis |
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| DE69732640D1 DE69732640D1 (de) | 2005-04-07 |
| DE69732640T2 true DE69732640T2 (de) | 2006-01-12 |
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| DE69732640T Expired - Lifetime DE69732640T2 (de) | 1996-09-09 | 1997-09-09 | Festphasen-peptidsynthese |
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| PT (1) | PT929567E (https=) |
| WO (1) | WO1998011125A1 (https=) |
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| US6528486B1 (en) | 1999-07-12 | 2003-03-04 | Zealand Pharma A/S | Peptide agonists of GLP-1 activity |
| US7550425B2 (en) | 2000-06-16 | 2009-06-23 | Zealand Pharma A/S | Diuretic peptide conjugates |
| DK1737889T3 (da) | 2004-10-19 | 2011-01-03 | Lonza Ag | Fremgangsmåde til fastfase-peptidsyntese |
| DE602006020123D1 (de) | 2005-05-04 | 2011-03-31 | Zealand Pharma As | Glucagon-like-peptide-2- (glp-2-) analoga |
| GB0514071D0 (en) | 2005-07-07 | 2005-08-17 | Zealand Pharma As | N- or C- terminally modified small peptides |
| US20090171097A1 (en) * | 2005-11-22 | 2009-07-02 | Hiroshi Sugiyama | Automated solid phase synthesis of pyrrole-imidazole polyamide |
| UA96283C2 (uk) | 2005-12-23 | 2011-10-25 | Зіланд Фарма А/С | Модифіковані міметики лізину |
| KR100859972B1 (ko) | 2006-02-20 | 2008-09-25 | 이화여자대학교 산학협력단 | 막투과 단백질 도메인 펩타이드 |
| JP5328345B2 (ja) * | 2006-03-29 | 2013-10-30 | 株式会社糖鎖工学研究所 | ペプチドのチオエステル化合物の製造方法 |
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| PH12012502472A1 (en) | 2010-06-24 | 2013-03-25 | Zealand Pharma As | Glucagon analogues |
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| WO2013098408A1 (en) | 2011-12-30 | 2013-07-04 | Zealand Pharma A/S | Glucagon and cck receptor agonist peptide conjugates |
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Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5116666A (https=) * | 1974-07-30 | 1976-02-10 | Shionogi Seiyaku Kk | |
| US5021550A (en) * | 1986-10-07 | 1991-06-04 | Thomas Jefferson University | Method for preventing deletion sequences in solid phase synthesis |
| JP2807287B2 (ja) * | 1989-10-13 | 1998-10-08 | 株式会社医学生物学研究所 | ペプチドおよびその用途 |
| CA2170030A1 (en) * | 1993-09-14 | 1995-03-23 | Robert A. Lazarus | Pharmaceutical compositions containing ecotin and homologs thereof |
| US7176282B1 (en) * | 1996-09-09 | 2007-02-13 | Zealand Pharma A/S | Solid-phase peptide synthesis and agent for use in such synthesis |
| JP4394279B2 (ja) * | 1998-03-09 | 2010-01-06 | ジーランド ファーマ アクティーゼルスカブ | 酵素加水分解に対する傾向が減少した薬理学的に活性なペプチド複合体 |
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1997
- 1997-09-09 CZ CZ1999803A patent/CZ295838B6/cs not_active IP Right Cessation
- 1997-09-09 DK DK97939974T patent/DK0929567T3/da active
- 1997-09-09 AT AT97939974T patent/ATE290014T1/de active
- 1997-09-09 AU AU41993/97A patent/AU723268B2/en not_active Ceased
- 1997-09-09 EP EP97939974A patent/EP0929567B1/en not_active Expired - Lifetime
- 1997-09-09 PT PT97939974T patent/PT929567E/pt unknown
- 1997-09-09 DE DE69732640T patent/DE69732640T2/de not_active Expired - Lifetime
- 1997-09-09 ES ES97939974T patent/ES2239364T3/es not_active Expired - Lifetime
- 1997-09-09 IL IL12882997A patent/IL128829A/xx not_active IP Right Cessation
- 1997-09-09 CA CA002265900A patent/CA2265900C/en not_active Expired - Lifetime
- 1997-09-09 HU HU0102900A patent/HU230354B1/hu not_active IP Right Cessation
- 1997-09-09 JP JP51316698A patent/JP4405594B2/ja not_active Expired - Fee Related
- 1997-09-09 WO PCT/DK1997/000375 patent/WO1998011125A1/en not_active Ceased
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2006
- 2006-06-19 US US11/455,388 patent/US7348404B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU723268B2 (en) | 2000-08-24 |
| JP2001500134A (ja) | 2001-01-09 |
| JP4405594B2 (ja) | 2010-01-27 |
| WO1998011125A1 (en) | 1998-03-19 |
| ATE290014T1 (de) | 2005-03-15 |
| US20070004905A1 (en) | 2007-01-04 |
| EP0929567B1 (en) | 2005-03-02 |
| ES2239364T3 (es) | 2005-09-16 |
| CZ295838B6 (cs) | 2005-11-16 |
| PT929567E (pt) | 2005-07-29 |
| HUP0102900A3 (en) | 2002-02-28 |
| CA2265900C (en) | 2007-07-31 |
| DE69732640D1 (de) | 2005-04-07 |
| IL128829A0 (en) | 2000-01-31 |
| CA2265900A1 (en) | 1998-03-19 |
| IL128829A (en) | 2005-08-31 |
| US7348404B2 (en) | 2008-03-25 |
| DK0929567T3 (da) | 2005-06-27 |
| HU230354B1 (hu) | 2016-02-29 |
| CZ80399A3 (cs) | 1999-08-11 |
| AU4199397A (en) | 1998-04-02 |
| EP0929567A1 (en) | 1999-07-21 |
| HUP0102900A2 (hu) | 2002-01-28 |
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