DE69729179T2 - Lückenhaft Zucker-modifizierte Oligonukleotide - Google Patents

Lückenhaft Zucker-modifizierte Oligonukleotide Download PDF

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Publication number
DE69729179T2
DE69729179T2 DE69729179T DE69729179T DE69729179T2 DE 69729179 T2 DE69729179 T2 DE 69729179T2 DE 69729179 T DE69729179 T DE 69729179T DE 69729179 T DE69729179 T DE 69729179T DE 69729179 T2 DE69729179 T2 DE 69729179T2
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Prior art keywords
oligonucleotides
oligonucleotide
sequence
sub
ras
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Expired - Lifetime
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DE69729179T
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German (de)
English (en)
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DE69729179D1 (de
Inventor
Phillip D. Cook
Brett P. Monia
Karl-Heinz Altmann
Pierre Martin
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Novartis AG
Ionis Pharmaceuticals Inc
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Novartis AG
Isis Pharmaceuticals Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69729179T 1996-02-14 1997-02-07 Lückenhaft Zucker-modifizierte Oligonukleotide Expired - Lifetime DE69729179T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1162096P 1996-02-14 1996-02-14
US11620P 1996-02-14
PCT/US1997/002043 WO1997030067A1 (en) 1996-02-14 1997-02-07 Sugar-modified gapped oligonucleotides

Publications (2)

Publication Number Publication Date
DE69729179D1 DE69729179D1 (de) 2004-06-24
DE69729179T2 true DE69729179T2 (de) 2004-12-30

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DE69729179T Expired - Lifetime DE69729179T2 (de) 1996-02-14 1997-02-07 Lückenhaft Zucker-modifizierte Oligonukleotide

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US (1) US6451991B1 (show.php)
EP (1) EP0882061B1 (show.php)
JP (1) JP4293636B2 (show.php)
KR (1) KR19990082476A (show.php)
CN (1) CN1214688A (show.php)
AT (1) ATE267207T1 (show.php)
AU (1) AU725262B2 (show.php)
BR (1) BR9707529A (show.php)
CA (2) CA2246229C (show.php)
CZ (1) CZ243498A3 (show.php)
DE (1) DE69729179T2 (show.php)
DK (1) DK0882061T3 (show.php)
ES (1) ES2221039T3 (show.php)
HU (1) HUP9901118A3 (show.php)
IL (1) IL125759A0 (show.php)
NO (1) NO983718L (show.php)
NZ (1) NZ331217A (show.php)
PL (1) PL328563A1 (show.php)
SK (1) SK109198A3 (show.php)
TR (1) TR199801581T2 (show.php)
WO (1) WO1997030067A1 (show.php)
ZA (1) ZA971208B (show.php)

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KR19990082476A (ko) 1999-11-25
IL125759A0 (en) 1999-04-11
DE69729179D1 (de) 2004-06-24
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US6451991B1 (en) 2002-09-17
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CN1214688A (zh) 1999-04-21
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ATE267207T1 (de) 2004-06-15
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CA2749312A1 (en) 1997-08-21
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DK0882061T3 (da) 2004-09-27
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