DE69604509T2 - Vorrichtung zur verabreichung von medikamenten und genen durch elektroporation - Google Patents

Vorrichtung zur verabreichung von medikamenten und genen durch elektroporation

Info

Publication number
DE69604509T2
DE69604509T2 DE69604509T DE69604509T DE69604509T2 DE 69604509 T2 DE69604509 T2 DE 69604509T2 DE 69604509 T DE69604509 T DE 69604509T DE 69604509 T DE69604509 T DE 69604509T DE 69604509 T2 DE69604509 T2 DE 69604509T2
Authority
DE
Germany
Prior art keywords
electroporation
genes
administrating
medicines
tumors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69604509T
Other languages
English (en)
Other versions
DE69604509D1 (de
Inventor
S Dev
Gunter Hofmann
Richard Gilbert
Yosuhiko Hayakawa
Richard Heller
Mark Jaroszeski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetronics Inc
Original Assignee
Genetronics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/467,566 external-priority patent/US5702359A/en
Application filed by Genetronics Inc filed Critical Genetronics Inc
Publication of DE69604509D1 publication Critical patent/DE69604509D1/de
Application granted granted Critical
Publication of DE69604509T2 publication Critical patent/DE69604509T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/02—Electrical or electromagnetic means, e.g. for electroporation or for cell fusion

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Electromagnetism (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Electrotherapy Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
DE69604509T 1995-06-06 1996-05-22 Vorrichtung zur verabreichung von medikamenten und genen durch elektroporation Expired - Lifetime DE69604509T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/467,566 US5702359A (en) 1995-06-06 1995-06-06 Needle electrodes for mediated delivery of drugs and genes
US08/537,265 US5993434A (en) 1993-04-01 1995-09-29 Method of treatment using electroporation mediated delivery of drugs and genes
PCT/US1996/007470 WO1996039226A1 (en) 1995-06-06 1996-05-22 Method of treatment using electroporation-mediated delivery of drugs and genes

Publications (2)

Publication Number Publication Date
DE69604509D1 DE69604509D1 (de) 1999-11-04
DE69604509T2 true DE69604509T2 (de) 2000-01-13

Family

ID=27042102

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69604509T Expired - Lifetime DE69604509T2 (de) 1995-06-06 1996-05-22 Vorrichtung zur verabreichung von medikamenten und genen durch elektroporation

Country Status (12)

Country Link
US (6) US5993434A (de)
EP (1) EP0874663B1 (de)
JP (1) JPH11506630A (de)
KR (1) KR100260238B1 (de)
CN (1) CN1150950C (de)
AT (1) ATE185083T1 (de)
AU (1) AU702054B2 (de)
CA (1) CA2218255C (de)
DE (1) DE69604509T2 (de)
ES (1) ES2140096T3 (de)
GR (1) GR3031963T3 (de)
WO (1) WO1996039226A1 (de)

Cited By (3)

* Cited by examiner, † Cited by third party
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DE102005062933A1 (de) * 2005-08-24 2007-03-22 Triton Gmbh Verfahren zur Behandlung von eine Zellstruktur aufweisenden Rohstoffen in der fleisch-, fleischnebenprodukte-, fisch- und seafoodverarbeitenden Nahrungsmittelindustrie
DE102008008614A1 (de) 2008-02-12 2009-08-13 Leibniz-Institut für Plasmaforschung und Technologie e.V. Plama-Gerät zur selektiven Behandlung elektroporierter Zellen
WO2011018423A2 (de) 2009-08-11 2011-02-17 Leibniz-Institut Für Plasmaforschung Und Technologie E. V. Vorrichtung und verfahren zur behandlung von lebenden zellen mittels eines plasmas

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* Cited by examiner, † Cited by third party
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US6569149B2 (en) 2003-05-27
US6418341B1 (en) 2002-07-09
DE69604509D1 (de) 1999-11-04
KR100260238B1 (ko) 2000-07-01
WO1996039226A1 (en) 1996-12-12
GR3031963T3 (en) 2000-03-31
EP0874663A1 (de) 1998-11-04
AU702054B2 (en) 1999-02-11
CN1187145A (zh) 1998-07-08
US20020198485A1 (en) 2002-12-26
US5993434A (en) 1999-11-30
AU5925996A (en) 1996-12-24
US20030009148A1 (en) 2003-01-09
US6567694B2 (en) 2003-05-20
EP0874663B1 (de) 1999-09-29
US20030097089A1 (en) 2003-05-22
CA2218255A1 (en) 1996-12-12
JPH11506630A (ja) 1999-06-15
CN1150950C (zh) 2004-05-26
CA2218255C (en) 2001-11-20
ATE185083T1 (de) 1999-10-15
KR19990021949A (ko) 1999-03-25
US6451002B1 (en) 2002-09-17
ES2140096T3 (es) 2000-02-16
US6763264B2 (en) 2004-07-13

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