ATE402732T1 - Verfahren zur behandlung von biologischen materialien mit übersetzenden elektrischen feldern und elektroden-polaritäts-umkehr - Google Patents
Verfahren zur behandlung von biologischen materialien mit übersetzenden elektrischen feldern und elektroden-polaritäts-umkehrInfo
- Publication number
- ATE402732T1 ATE402732T1 AT03719469T AT03719469T ATE402732T1 AT E402732 T1 ATE402732 T1 AT E402732T1 AT 03719469 T AT03719469 T AT 03719469T AT 03719469 T AT03719469 T AT 03719469T AT E402732 T1 ATE402732 T1 AT E402732T1
- Authority
- AT
- Austria
- Prior art keywords
- electrodes
- treatment area
- rows
- successive
- waveform generator
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
- A61N1/0476—Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
- A61N1/303—Constructional details
- A61N1/306—Arrangements where at least part of the apparatus is introduced into the body
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37243602P | 2002-04-16 | 2002-04-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE402732T1 true ATE402732T1 (de) | 2008-08-15 |
Family
ID=29250852
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03719469T ATE402732T1 (de) | 2002-04-16 | 2003-04-11 | Verfahren zur behandlung von biologischen materialien mit übersetzenden elektrischen feldern und elektroden-polaritäts-umkehr |
Country Status (9)
Country | Link |
---|---|
US (1) | US20060089674A1 (de) |
EP (1) | EP1494752B1 (de) |
JP (1) | JP4499427B2 (de) |
CN (1) | CN100455328C (de) |
AT (1) | ATE402732T1 (de) |
AU (1) | AU2003223351A1 (de) |
CA (1) | CA2482183A1 (de) |
DE (1) | DE60322523D1 (de) |
WO (1) | WO2003089046A1 (de) |
Families Citing this family (68)
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USRE44145E1 (en) | 2000-07-07 | 2013-04-09 | A.V. Topchiev Institute Of Petrochemical Synthesis | Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties |
US20050215727A1 (en) | 2001-05-01 | 2005-09-29 | Corium | Water-absorbent adhesive compositions and associated methods of manufacture and use |
US8206738B2 (en) | 2001-05-01 | 2012-06-26 | Corium International, Inc. | Hydrogel compositions with an erodible backing member |
US8840918B2 (en) | 2001-05-01 | 2014-09-23 | A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences | Hydrogel compositions for tooth whitening |
US8541021B2 (en) | 2001-05-01 | 2013-09-24 | A.V. Topchiev Institute Of Petrochemical Synthesis | Hydrogel compositions demonstrating phase separation on contact with aqueous media |
ATE438418T1 (de) | 2001-05-01 | 2009-08-15 | Av Topchiev Inst Petrochemical | Hydrogel-zusammensetzungen |
US20070135875A1 (en) | 2002-04-08 | 2007-06-14 | Ardian, Inc. | Methods and apparatus for thermally-induced renal neuromodulation |
US7620451B2 (en) | 2005-12-29 | 2009-11-17 | Ardian, Inc. | Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach |
US8774922B2 (en) | 2002-04-08 | 2014-07-08 | Medtronic Ardian Luxembourg S.A.R.L. | Catheter apparatuses having expandable balloons for renal neuromodulation and associated systems and methods |
US7162303B2 (en) | 2002-04-08 | 2007-01-09 | Ardian, Inc. | Renal nerve stimulation method and apparatus for treatment of patients |
US7756583B2 (en) * | 2002-04-08 | 2010-07-13 | Ardian, Inc. | Methods and apparatus for intravascularly-induced neuromodulation |
US8131371B2 (en) * | 2002-04-08 | 2012-03-06 | Ardian, Inc. | Methods and apparatus for monopolar renal neuromodulation |
US8774913B2 (en) | 2002-04-08 | 2014-07-08 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and apparatus for intravasculary-induced neuromodulation |
US9636174B2 (en) | 2002-04-08 | 2017-05-02 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for therapeutic renal neuromodulation |
US20080213331A1 (en) | 2002-04-08 | 2008-09-04 | Ardian, Inc. | Methods and devices for renal nerve blocking |
US7653438B2 (en) | 2002-04-08 | 2010-01-26 | Ardian, Inc. | Methods and apparatus for renal neuromodulation |
US8145317B2 (en) * | 2002-04-08 | 2012-03-27 | Ardian, Inc. | Methods for renal neuromodulation |
US6978174B2 (en) | 2002-04-08 | 2005-12-20 | Ardian, Inc. | Methods and devices for renal nerve blocking |
US9308044B2 (en) | 2002-04-08 | 2016-04-12 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for therapeutic renal neuromodulation |
US9308043B2 (en) | 2002-04-08 | 2016-04-12 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for monopolar renal neuromodulation |
US8145316B2 (en) | 2002-04-08 | 2012-03-27 | Ardian, Inc. | Methods and apparatus for renal neuromodulation |
US7853333B2 (en) | 2002-04-08 | 2010-12-14 | Ardian, Inc. | Methods and apparatus for multi-vessel renal neuromodulation |
US8175711B2 (en) | 2002-04-08 | 2012-05-08 | Ardian, Inc. | Methods for treating a condition or disease associated with cardio-renal function |
US7617005B2 (en) | 2002-04-08 | 2009-11-10 | Ardian, Inc. | Methods and apparatus for thermally-induced renal neuromodulation |
US20070129761A1 (en) | 2002-04-08 | 2007-06-07 | Ardian, Inc. | Methods for treating heart arrhythmia |
US8347891B2 (en) | 2002-04-08 | 2013-01-08 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen |
US20140018880A1 (en) | 2002-04-08 | 2014-01-16 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for monopolar renal neuromodulation |
US8150519B2 (en) | 2002-04-08 | 2012-04-03 | Ardian, Inc. | Methods and apparatus for bilateral renal neuromodulation |
US20040082859A1 (en) | 2002-07-01 | 2004-04-29 | Alan Schaer | Method and apparatus employing ultrasound energy to treat body sphincters |
WO2005074894A1 (en) | 2004-01-30 | 2005-08-18 | Corium International | Rapidly dissolving film for delivery of an active agent |
US7775087B2 (en) * | 2004-03-16 | 2010-08-17 | Northwestern University | Microchannel forming method and nanotipped dispensing device having a microchannel |
BRPI0512607A (pt) * | 2004-06-24 | 2008-03-25 | Sphergen | dispositivo para a transferência de moléculas para células que utiliza uma força elétrica |
CN103497713B (zh) | 2004-08-05 | 2018-07-17 | 考里安国际公司 | 粘合剂组合物 |
US7937143B2 (en) | 2004-11-02 | 2011-05-03 | Ardian, Inc. | Methods and apparatus for inducing controlled renal neuromodulation |
US20060264805A1 (en) * | 2005-05-11 | 2006-11-23 | Corium International, Inc. | Permeabilization of biological membranes |
US8353906B2 (en) * | 2005-08-01 | 2013-01-15 | Ceramatec, Inc. | Electrochemical probe and method for in situ treatment of a tissue |
ATE466537T1 (de) * | 2006-01-03 | 2010-05-15 | Alcon Inc | System zur spaltung und entfernung von proteinösem gewebe |
US20080287857A1 (en) * | 2006-02-11 | 2008-11-20 | Rune Kjeken | Device and method for single-needle in vivo electroporation |
EP1981581B1 (de) | 2006-02-11 | 2016-04-13 | Genetronics, Inc. | Vorrichtung zur in-vivo-einzelnadelelektroporation |
EP2160201B1 (de) * | 2007-05-21 | 2014-04-09 | Cellectis | Vorrichtung zur verabreichung von polynukleotidimpfstoffen an säugerhaut |
TWI401432B (zh) * | 2008-12-05 | 2013-07-11 | Univ Nat Taiwan | 高密度微電極陣列及其序列式控制方法 |
US8652129B2 (en) | 2008-12-31 | 2014-02-18 | Medtronic Ardian Luxembourg S.A.R.L. | Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation |
WO2010080886A1 (en) | 2009-01-09 | 2010-07-15 | Recor Medical, Inc. | Methods and apparatus for treatment of mitral valve in insufficiency |
AU2010204986B2 (en) | 2009-01-14 | 2016-06-02 | Corium International, Inc. | Transdermal administration of tamsulosin |
US20110118729A1 (en) * | 2009-11-13 | 2011-05-19 | Alcon Research, Ltd | High-intensity pulsed electric field vitrectomy apparatus with load detection |
US20110118734A1 (en) * | 2009-11-16 | 2011-05-19 | Alcon Research, Ltd. | Capsularhexis device using pulsed electric fields |
US20110135626A1 (en) * | 2009-12-08 | 2011-06-09 | Alcon Research, Ltd. | Localized Chemical Lysis of Ocular Tissue |
US20110144562A1 (en) * | 2009-12-14 | 2011-06-16 | Alcon Research, Ltd. | Localized Pharmacological Treatment of Ocular Tissue Using High-Intensity Pulsed Electrical Fields |
WO2011081897A1 (en) * | 2009-12-15 | 2011-07-07 | Alcon Research, Ltd. | High-intensity pulsed electric field vitrectomy apparatus |
US8546979B2 (en) | 2010-08-11 | 2013-10-01 | Alcon Research, Ltd. | Self-matching pulse generator with adjustable pulse width and pulse frequency |
JP6046041B2 (ja) | 2010-10-25 | 2016-12-14 | メドトロニック アーディアン ルクセンブルク ソシエテ ア レスポンサビリテ リミテ | 神経変調療法の評価及びフィードバックのためのデバイス、システム、及び方法 |
US9750568B2 (en) | 2012-03-08 | 2017-09-05 | Medtronic Ardian Luxembourg S.A.R.L. | Ovarian neuromodulation and associated systems and methods |
US9510777B2 (en) | 2012-03-08 | 2016-12-06 | Medtronic Ardian Luxembourg S.A.R.L. | Monitoring of neuromodulation using biomarkers |
US20140110296A1 (en) | 2012-10-19 | 2014-04-24 | Medtronic Ardian Luxembourg S.A.R.L. | Packaging for Catheter Treatment Devices and Associated Devices, Systems, and Methods |
WO2014201511A1 (en) * | 2013-06-21 | 2014-12-24 | Gary David Housley | Method and apparatus for close-field electroporation |
CN103555574A (zh) | 2013-11-11 | 2014-02-05 | 苏州文曲生物微系统有限公司 | 一种流式电穿孔装置 |
JP6723153B2 (ja) | 2013-12-05 | 2020-07-15 | アールエフイーエムビー ホールディングス リミテッド ライアビリティ カンパニー | 生体内の望ましくない軟部組織を切除するシステム |
US10194979B1 (en) | 2014-03-28 | 2019-02-05 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for catheter-based renal neuromodulation |
US9980766B1 (en) | 2014-03-28 | 2018-05-29 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and systems for renal neuromodulation |
US10194980B1 (en) | 2014-03-28 | 2019-02-05 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for catheter-based renal neuromodulation |
US9833617B2 (en) * | 2014-07-25 | 2017-12-05 | Loyalty Based Innovations, LLC | Apparatus and method for treating multiple tumors in patients with metastatic disease by electric fields |
KR101788301B1 (ko) * | 2015-09-17 | 2017-10-20 | 주식회사 엘림텍 | 전기천공장치 및 그 제어방법 |
GB2554455A (en) * | 2016-09-29 | 2018-04-04 | Feeligreen Sa | Skin treatment device and method for delivery of an active ingredient into the human skin by means of iontophoresis, using an array of electrodes |
CN106955418A (zh) * | 2017-04-19 | 2017-07-18 | 湖南省万卓医疗器械有限公司 | 可动态调度电极板极性的三维动态治疗仪 |
US20210386474A1 (en) * | 2018-11-05 | 2021-12-16 | Region Hovedstaden V/Herlev Hospital | Electrode assembly for improved electric field distribution |
EP3893986A4 (de) | 2018-12-13 | 2022-08-24 | NewSouth Innovations Pty Limited | Verfahren und system zur steuerung der molekularen elektroübertragung |
WO2020190688A1 (en) * | 2019-03-15 | 2020-09-24 | Boston Scientific Scimed, Inc. | Spatially multiplexed waveform for selective cell ablation |
EP4025144B1 (de) | 2019-09-02 | 2023-09-06 | Mirai Medical Limited | Elektroporationsgerät |
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FR2703253B1 (fr) | 1993-03-30 | 1995-06-23 | Centre Nat Rech Scient | Applicateur d'impulsions electriques pour traitement de tissus biologiques. |
US5702359A (en) | 1995-06-06 | 1997-12-30 | Genetronics, Inc. | Needle electrodes for mediated delivery of drugs and genes |
US5993434A (en) | 1993-04-01 | 1999-11-30 | Genetronics, Inc. | Method of treatment using electroporation mediated delivery of drugs and genes |
US6010613A (en) * | 1995-12-08 | 2000-01-04 | Cyto Pulse Sciences, Inc. | Method of treating materials with pulsed electrical fields |
EP0892654B1 (de) * | 1996-04-04 | 2003-06-11 | Medtronic, Inc. | Vorrichtung zur stimulation von lebendem gewebe und entsprechende aufzeichnung |
KR100427786B1 (ko) | 1997-04-03 | 2004-04-30 | 일렉트로우펙트 에이에스 | 약물과 핵산의 골격 근육 내 주입 장치 및 방법 |
US5873849A (en) | 1997-04-24 | 1999-02-23 | Ichor Medical Systems, Inc. | Electrodes and electrode arrays for generating electroporation inducing electrical fields |
US6117660A (en) * | 1997-06-10 | 2000-09-12 | Cytopulse Sciences, Inc. | Method and apparatus for treating materials with electrical fields having varying orientations |
US6055453A (en) | 1997-08-01 | 2000-04-25 | Genetronics, Inc. | Apparatus for addressing needle array electrodes for electroporation therapy |
US6241701B1 (en) * | 1997-08-01 | 2001-06-05 | Genetronics, Inc. | Apparatus for electroporation mediated delivery of drugs and genes |
US7456012B2 (en) * | 1997-11-06 | 2008-11-25 | Cellectricon Ab | Method and apparatus for spatially confined electroporation |
US6208893B1 (en) * | 1998-01-27 | 2001-03-27 | Genetronics, Inc. | Electroporation apparatus with connective electrode template |
CN1233511A (zh) * | 1998-04-24 | 1999-11-03 | 刘凤瑞 | 循环脉冲序列仿真治疗仪 |
EP1163024B1 (de) * | 1999-01-28 | 2003-12-17 | Cyto Pulse Sciences, Inc. | Einbringen von makromolekülen in zellen |
US6713291B2 (en) * | 1999-01-28 | 2004-03-30 | Alan D. King | Electrodes coated with treating agent and uses thereof |
US6428504B1 (en) * | 2000-04-06 | 2002-08-06 | Varian Medical Systems, Inc. | Multipurpose template and needles for the delivery and monitoring of multiple minimally invasive therapies |
US6546290B1 (en) * | 2000-04-12 | 2003-04-08 | Roamitron Holding S.A. | Method and apparatus for electromedical therapy |
US6795728B2 (en) * | 2001-08-17 | 2004-09-21 | Minnesota Medical Physics, Llc | Apparatus and method for reducing subcutaneous fat deposits by electroporation |
-
2003
- 2003-04-11 JP JP2003585797A patent/JP4499427B2/ja not_active Expired - Fee Related
- 2003-04-11 AT AT03719469T patent/ATE402732T1/de not_active IP Right Cessation
- 2003-04-11 WO PCT/US2003/009208 patent/WO2003089046A1/en active Application Filing
- 2003-04-11 EP EP03719469A patent/EP1494752B1/de not_active Expired - Lifetime
- 2003-04-11 CA CA002482183A patent/CA2482183A1/en not_active Abandoned
- 2003-04-11 AU AU2003223351A patent/AU2003223351A1/en not_active Abandoned
- 2003-04-11 CN CNB038131641A patent/CN100455328C/zh not_active Expired - Fee Related
- 2003-04-11 US US10/510,710 patent/US20060089674A1/en not_active Abandoned
- 2003-04-11 DE DE60322523T patent/DE60322523D1/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1494752B1 (de) | 2008-07-30 |
CN1658924A (zh) | 2005-08-24 |
JP2005523085A (ja) | 2005-08-04 |
WO2003089046A1 (en) | 2003-10-30 |
AU2003223351A1 (en) | 2003-11-03 |
CA2482183A1 (en) | 2003-10-30 |
JP4499427B2 (ja) | 2010-07-07 |
EP1494752A4 (de) | 2006-09-13 |
EP1494752A1 (de) | 2005-01-12 |
DE60322523D1 (de) | 2008-09-11 |
CN100455328C (zh) | 2009-01-28 |
US20060089674A1 (en) | 2006-04-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |