ATE220923T1 - Rekombinante adenoviren und deren verwendung in der gentherapie zur behandlung von augenerkrankungen - Google Patents

Rekombinante adenoviren und deren verwendung in der gentherapie zur behandlung von augenerkrankungen

Info

Publication number
ATE220923T1
ATE220923T1 AT94908383T AT94908383T ATE220923T1 AT E220923 T1 ATE220923 T1 AT E220923T1 AT 94908383 T AT94908383 T AT 94908383T AT 94908383 T AT94908383 T AT 94908383T AT E220923 T1 ATE220923 T1 AT E220923T1
Authority
AT
Austria
Prior art keywords
eye diseases
treatment
recombinant adenoviruses
gene therapy
adenoviruses
Prior art date
Application number
AT94908383T
Other languages
English (en)
Inventor
Pascale Briand
Michel Perricaudet
Original Assignee
Aventis Pharma Sa
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa, Inst Nat Sante Rech Med filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of ATE220923T1 publication Critical patent/ATE220923T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT94908383T 1993-03-03 1994-02-28 Rekombinante adenoviren und deren verwendung in der gentherapie zur behandlung von augenerkrankungen ATE220923T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9302438A FR2702152B1 (fr) 1993-03-03 1993-03-03 Virus recombinants et leur utilisation en thérapie génique.
PCT/FR1994/000220 WO1994020146A1 (fr) 1993-03-03 1994-02-28 Adenovirus recombinants et leur utilisation en therapie genique pour le traitement des pathologies oculaires

Publications (1)

Publication Number Publication Date
ATE220923T1 true ATE220923T1 (de) 2002-08-15

Family

ID=9444602

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94908383T ATE220923T1 (de) 1993-03-03 1994-02-28 Rekombinante adenoviren und deren verwendung in der gentherapie zur behandlung von augenerkrankungen

Country Status (15)

Country Link
EP (1) EP0687184B1 (de)
JP (1) JP3835809B2 (de)
AT (1) ATE220923T1 (de)
AU (1) AU693782B2 (de)
CA (1) CA2154355A1 (de)
DE (1) DE69431046T2 (de)
DK (1) DK0687184T3 (de)
ES (1) ES2181710T3 (de)
FR (1) FR2702152B1 (de)
HU (1) HU218900B (de)
NO (1) NO319571B1 (de)
NZ (1) NZ262135A (de)
PT (1) PT687184E (de)
WO (1) WO1994020146A1 (de)
ZA (1) ZA941426B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792751A (en) * 1992-04-13 1998-08-11 Baylor College Of Medicine Tranformation of cells associated with fluid spaces
FR2717823B1 (fr) * 1994-03-23 1996-04-26 Rhone Poulenc Rorer Sa Virus recombinants, préparation et utilisation en thérapie génique.
IL113052A0 (en) * 1994-03-23 1995-06-29 Rhone Poulenc Rorer Sa Recombinant viruses, their preparation and their use in gene therapy
FR2726575B1 (fr) * 1994-11-09 1996-12-20 Rhone Poulenc Rorer Sa Virus recombinants, preparation et utilisation en therapie genique
FR2717824B1 (fr) * 1994-03-25 1996-04-26 Rhone Poulenc Rorer Sa Virus recombinants, préparation et utilisation en thérapie génique.
FR2718150B1 (fr) 1994-03-29 1996-04-26 Rhone Poulenc Rorer Sa Virus recombinants, préparation et utilisation en thérapie génique.
US5827702A (en) * 1994-10-31 1998-10-27 Genentech, Inc. Ocular gene therapy
US6107027A (en) * 1994-12-14 2000-08-22 University Of Washington Ribozymes for treating hepatitis C
US6696423B1 (en) 1997-08-29 2004-02-24 Biogen, Inc. Methods and compositions for therapies using genes encoding secreted proteins such as interferon-beta
US6489305B1 (en) 1998-05-08 2002-12-03 Canji, Inc. Methods and compositions for the treatment of ocular diseases
JP2004500369A (ja) * 1999-12-30 2004-01-08 アバンテイス・フアルマ・エス・アー 角膜血管新生を治療するための抗血管形成因子をコードする核酸を含むベクターの使用
FR2803207B1 (fr) * 1999-12-30 2004-04-30 Aventis Pharma Sa Utilisation d'un vecteur comprenant un acide nucleique codant pour un facteur anti-angiogenique pour le traitement des neovascularisations corneennes
US6821775B1 (en) 2000-02-11 2004-11-23 Genvec, Inc. Viral vector encoding pigment epithelium-derived factor
US20030158112A1 (en) 2002-02-15 2003-08-21 Johns Hopkins University School Of Medicine Selective induction of apoptosis to treat ocular disease
BRPI0416920A (pt) 2003-11-24 2007-01-23 Canji Inc redução de cicatriz dérmica
WO2006031689A2 (en) 2004-09-13 2006-03-23 Genzyme Corporation Multimeric constructs
HUE035554T2 (en) 2010-08-06 2018-05-02 Genzyme Corp VEGF antagonist compositions and their uses

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE155038T1 (de) * 1988-09-13 1997-07-15 Biosource Tech Inc Zusammensetzung zur behandlung von degenerativen krankheiten des nervensystems
EP0578776A4 (de) * 1991-04-05 1995-04-12 Edison Animal Biotech Center Hemmung von retroviren mittels zu verpackungssequenzen komplementärer antisense-nukleinsäuren.

Also Published As

Publication number Publication date
PT687184E (pt) 2002-12-31
ZA941426B (en) 1994-10-04
ES2181710T3 (es) 2003-03-01
DK0687184T3 (da) 2002-10-28
CA2154355A1 (fr) 1994-09-15
HU9502573D0 (en) 1995-10-30
DE69431046D1 (de) 2002-08-29
NO953329L (no) 1995-08-24
FR2702152A1 (fr) 1994-09-09
WO1994020146A1 (fr) 1994-09-15
EP0687184A1 (de) 1995-12-20
HUT73215A (en) 1996-06-28
AU693782B2 (en) 1998-07-09
NO319571B1 (no) 2005-08-29
NO953329D0 (no) 1995-08-24
EP0687184B1 (de) 2002-07-24
AU6144494A (en) 1994-09-26
DE69431046T2 (de) 2003-02-13
FR2702152B1 (fr) 1995-05-24
JP3835809B2 (ja) 2006-10-18
NZ262135A (en) 2000-12-22
HU218900B (hu) 2000-12-28
JPH08509208A (ja) 1996-10-01

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