DE69419447T2 - Salbe zur Wundbehandlung - Google Patents

Salbe zur Wundbehandlung

Info

Publication number
DE69419447T2
DE69419447T2 DE69419447T DE69419447T DE69419447T2 DE 69419447 T2 DE69419447 T2 DE 69419447T2 DE 69419447 T DE69419447 T DE 69419447T DE 69419447 T DE69419447 T DE 69419447T DE 69419447 T2 DE69419447 T2 DE 69419447T2
Authority
DE
Germany
Prior art keywords
weight
gel
hexylene glycol
glycol
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69419447T
Other languages
German (de)
English (en)
Other versions
DE69419447D1 (de
Inventor
Craig J. Hardy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ethicon Inc
Original Assignee
Johnson and Johnson Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson and Johnson Medical Inc filed Critical Johnson and Johnson Medical Inc
Application granted granted Critical
Publication of DE69419447D1 publication Critical patent/DE69419447D1/de
Publication of DE69419447T2 publication Critical patent/DE69419447T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/14Alkali metal chlorides; Alkaline earth metal chlorides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015Drug-containing film-forming compositions, e.g. spray-on
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/20Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/225Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28Polysaccharides or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0052Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061Use of materials characterised by their function or physical properties
    • A61L26/0071Plasticisers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Detergent Compositions (AREA)
  • Cosmetics (AREA)
DE69419447T 1993-03-23 1994-03-22 Salbe zur Wundbehandlung Expired - Lifetime DE69419447T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9306039A GB2276819B (en) 1993-03-23 1993-03-23 Aqueous wound treatment composition comprising a polysaccharide and hexylene glycol

Publications (2)

Publication Number Publication Date
DE69419447D1 DE69419447D1 (de) 1999-08-19
DE69419447T2 true DE69419447T2 (de) 2000-01-05

Family

ID=10732613

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69419447T Expired - Lifetime DE69419447T2 (de) 1993-03-23 1994-03-22 Salbe zur Wundbehandlung

Country Status (12)

Country Link
US (2) US5723144A (enExample)
EP (1) EP0621031B1 (enExample)
JP (1) JP2763492B2 (enExample)
AT (1) ATE182072T1 (enExample)
AU (1) AU681618B2 (enExample)
BR (1) BR9401241A (enExample)
CA (1) CA2119516C (enExample)
DE (1) DE69419447T2 (enExample)
ES (1) ES2135541T3 (enExample)
GB (1) GB2276819B (enExample)
IN (1) IN177229B (enExample)
ZA (1) ZA941827B (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5670169A (en) * 1993-12-20 1997-09-23 E.R. Squibb & Sons, Inc. Wound hydrating gel with novel preservative system and low cytotoxicity
GB2291348B (en) * 1994-07-18 1999-01-20 Johnson & Johnson Medical Sterile gel composition for wound treatment comprising alginate and polyhydric alcohol
EP0987019A1 (en) * 1998-09-01 2000-03-22 Virotex Corporation Topical antibiotic composition for rapid wound healing
GB9618570D0 (en) * 1996-09-05 1996-10-16 Courtaulds Fibres Holdings Ltd Improvements in or relating to wound dressings
GB9618573D0 (en) * 1996-09-05 1996-10-16 Courtaulds Fibres Holdings Ltd Wound dressings and manufacture thereof
RU2141818C1 (ru) * 1997-03-27 1999-11-27 Седов Валерий Николаевич Паста для лечения трофических язв и длительно незаживающих ран
RU2148989C1 (ru) * 1998-06-09 2000-05-20 Институт органической и физической химии им. А.Е. Арбузова Казанского научного центра РАН Препарат для лечения длительно не заживающих ран и трофических язв (варианты)
WO2000028978A1 (en) * 1998-11-18 2000-05-25 Medical Industries Corp. Agents for repairing damaged tissue sites
JP4558208B2 (ja) * 1998-11-24 2010-10-06 ジョンソン・アンド・ジョンソン・コンシューマー・カンパニーズ・インコーポレイテッド 吸収包帯と包帯上の活性成分の分配器として有効なコーティング
US6046160A (en) * 1999-07-22 2000-04-04 Deroyal Industries, Inc. Composition and method for enhancing wound healing
CA2390556C (en) 1999-11-09 2009-05-19 Denki Kagaku Kogyo Kabushiki Kaisha Use of soluble cellulose derivative having been made hardly soluble in water and method for producing it
US20070009586A1 (en) * 2000-02-29 2007-01-11 Cohen Kelman I Wound dressings containing complexes of transition metals and alginate for elastase sequestering
US20040001878A1 (en) * 2002-06-26 2004-01-01 Deroyal Industries, Inc. Infused wound care dressings
US20070004672A1 (en) * 2005-07-01 2007-01-04 Dharmendra Jani Long lasting alginate dry eye, related methods of manufacture and methods of use
DE102005060461A1 (de) 2005-12-17 2007-07-12 Paul Hartmann Ag Medizinische Zusammensetzung
EP2296637B1 (en) * 2008-04-24 2014-04-02 Medtronic, Inc Chitosan-containing protective composition
EP2288389B1 (en) * 2008-04-24 2014-06-11 Medtronic, Inc Cold ionizing radiation sterilization
EP2310002B1 (en) * 2008-04-24 2016-11-02 Medtronic, Inc Protective gel based on chitosan and oxidized polysaccharide
US20090269417A1 (en) * 2008-04-24 2009-10-29 Medtronic, Inc. Thiolated chitosan gel
US9198997B2 (en) 2008-04-24 2015-12-01 Medtronic, Inc. Rehydratable thiolated polysaccharide particles and sponge
JP5582711B2 (ja) * 2008-09-25 2014-09-03 株式会社エー・アイ・システムプロダクト ローション状の塗薬
MD4197C1 (ro) * 2012-10-22 2013-09-30 Мария ДАНУ Metodă de tratament al ulcerelor trofice
US9023399B2 (en) 2012-11-16 2015-05-05 NU Technology, LLC Water-soluble anti-inflammatory cream with natural ingredients base
US9192574B2 (en) 2013-10-24 2015-11-24 Medtronic Xomed, Inc. Chitosan paste wound dressing
US9192692B2 (en) 2013-10-24 2015-11-24 Medtronic Xomed, Inc. Chitosan stenting paste
MX2017004520A (es) 2014-10-14 2018-03-15 Lynch Samuel Composiciones para tratar heridas.

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2075837B (en) * 1980-05-14 1984-03-14 Hisamitsu Pharmaceutical Co Topical pharmaceutical gel containing anti-inflammatory analgesic agents
FR2489145A1 (fr) * 1980-09-04 1982-03-05 Geistlich Soehne Ag Compositions pharmaceutiques accelerant la guerison de blessures
JPS57142913A (en) * 1981-02-27 1982-09-03 Nitto Electric Ind Co Ltd Donor of physiologically active substance
JPS58174484A (ja) * 1982-04-08 1983-10-13 Kao Corp 感圧性粘着テ−プ又はシ−ト
US4604384A (en) * 1982-06-24 1986-08-05 Smith Robert A Pharmaceutical gel composition
AU558482B2 (en) * 1982-06-24 1987-01-29 Chiltern Pharmaceuticals Pty. Limited Pharmaceutical gel composition
FR2532546B1 (fr) * 1982-09-07 1985-12-27 Biotrol Sa Lab Pate pour la protection de la peau
US4643856A (en) * 1985-03-21 1987-02-17 Moleculon, Inc. Process of making gelled cellulose triacetate product
US4666671A (en) * 1985-04-03 1987-05-19 Givaudan Corporation Method for deodorizing urinals and toilet bowls with fragranced gel blocks
JPS62123112A (ja) * 1985-11-22 1987-06-04 Sunstar Inc 軟膏基剤
GB8818114D0 (en) * 1988-07-29 1988-09-01 Johnson & Johnson Haemostatic wound dressing material
US5084427A (en) * 1990-10-22 1992-01-28 Uop Aqueous suspensions of aluminosilicate molecular sieves
US5385729A (en) * 1991-08-01 1995-01-31 Colgate Palmolive Company Viscoelastic personal care composition
JP3254013B2 (ja) * 1991-09-10 2002-02-04 ジョンソン・アンド・ジョンソン・メディカル・インコーポレイテッド 包帯材料およびその製造方法
GB9208731D0 (en) * 1992-04-22 1992-06-10 Squibb & Sons Inc Hydrocolloid wound gel
US5470576A (en) * 1992-06-08 1995-11-28 The Kendall Company Process for preparing the alginate-containing wound dressing
US5338541A (en) * 1992-10-15 1994-08-16 Calgon Corporation Dual cationic terpolymers providing superior conditioning properties in hair, skin and nail care products

Also Published As

Publication number Publication date
AU681618B2 (en) 1997-09-04
GB9306039D0 (en) 1993-05-12
GB2276819B (en) 1996-12-11
CA2119516C (en) 2005-09-06
US5723144A (en) 1998-03-03
ZA941827B (en) 1995-09-15
JP2763492B2 (ja) 1998-06-11
GB2276819A (en) 1994-10-12
ES2135541T3 (es) 1999-11-01
IN177229B (enExample) 1996-12-07
US5688522A (en) 1997-11-18
EP0621031B1 (en) 1999-07-14
EP0621031A2 (en) 1994-10-26
JPH07109220A (ja) 1995-04-25
ATE182072T1 (de) 1999-07-15
AU5794594A (en) 1994-09-29
EP0621031A3 (en) 1995-04-19
BR9401241A (pt) 1994-11-08
CA2119516A1 (en) 1994-09-24
DE69419447D1 (de) 1999-08-19

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Representative=s name: BOEHMERT & BOEHMERT, 28209 BREMEN