CA2119516C - Ointment for wound treatment - Google Patents
Ointment for wound treatment Download PDFInfo
- Publication number
- CA2119516C CA2119516C CA002119516A CA2119516A CA2119516C CA 2119516 C CA2119516 C CA 2119516C CA 002119516 A CA002119516 A CA 002119516A CA 2119516 A CA2119516 A CA 2119516A CA 2119516 C CA2119516 C CA 2119516C
- Authority
- CA
- Canada
- Prior art keywords
- weight
- gel
- glycol
- hexylene glycol
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 206010052428 Wound Diseases 0.000 title claims description 19
- 208000027418 Wounds and injury Diseases 0.000 title claims description 19
- 239000002674 ointment Substances 0.000 title description 8
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/20—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/225—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/28—Polysaccharides or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0023—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0052—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/0071—Plasticisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Hematology (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Detergent Compositions (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9306039.0 | 1993-03-23 | ||
| GB9306039A GB2276819B (en) | 1993-03-23 | 1993-03-23 | Aqueous wound treatment composition comprising a polysaccharide and hexylene glycol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2119516A1 CA2119516A1 (en) | 1994-09-24 |
| CA2119516C true CA2119516C (en) | 2005-09-06 |
Family
ID=10732613
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002119516A Expired - Fee Related CA2119516C (en) | 1993-03-23 | 1994-03-21 | Ointment for wound treatment |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US5723144A (enExample) |
| EP (1) | EP0621031B1 (enExample) |
| JP (1) | JP2763492B2 (enExample) |
| AT (1) | ATE182072T1 (enExample) |
| AU (1) | AU681618B2 (enExample) |
| BR (1) | BR9401241A (enExample) |
| CA (1) | CA2119516C (enExample) |
| DE (1) | DE69419447T2 (enExample) |
| ES (1) | ES2135541T3 (enExample) |
| GB (1) | GB2276819B (enExample) |
| IN (1) | IN177229B (enExample) |
| ZA (1) | ZA941827B (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5670169A (en) * | 1993-12-20 | 1997-09-23 | E.R. Squibb & Sons, Inc. | Wound hydrating gel with novel preservative system and low cytotoxicity |
| GB2291348B (en) * | 1994-07-18 | 1999-01-20 | Johnson & Johnson Medical | Sterile gel composition for wound treatment comprising alginate and polyhydric alcohol |
| EP0987019A1 (en) * | 1998-09-01 | 2000-03-22 | Virotex Corporation | Topical antibiotic composition for rapid wound healing |
| GB9618570D0 (en) * | 1996-09-05 | 1996-10-16 | Courtaulds Fibres Holdings Ltd | Improvements in or relating to wound dressings |
| GB9618573D0 (en) * | 1996-09-05 | 1996-10-16 | Courtaulds Fibres Holdings Ltd | Wound dressings and manufacture thereof |
| RU2141818C1 (ru) * | 1997-03-27 | 1999-11-27 | Седов Валерий Николаевич | Паста для лечения трофических язв и длительно незаживающих ран |
| RU2148989C1 (ru) * | 1998-06-09 | 2000-05-20 | Институт органической и физической химии им. А.Е. Арбузова Казанского научного центра РАН | Препарат для лечения длительно не заживающих ран и трофических язв (варианты) |
| WO2000028978A1 (en) * | 1998-11-18 | 2000-05-25 | Medical Industries Corp. | Agents for repairing damaged tissue sites |
| JP4558208B2 (ja) * | 1998-11-24 | 2010-10-06 | ジョンソン・アンド・ジョンソン・コンシューマー・カンパニーズ・インコーポレイテッド | 吸収包帯と包帯上の活性成分の分配器として有効なコーティング |
| US6046160A (en) * | 1999-07-22 | 2000-04-04 | Deroyal Industries, Inc. | Composition and method for enhancing wound healing |
| CA2390556C (en) | 1999-11-09 | 2009-05-19 | Denki Kagaku Kogyo Kabushiki Kaisha | Use of soluble cellulose derivative having been made hardly soluble in water and method for producing it |
| US20070009586A1 (en) * | 2000-02-29 | 2007-01-11 | Cohen Kelman I | Wound dressings containing complexes of transition metals and alginate for elastase sequestering |
| US20040001878A1 (en) * | 2002-06-26 | 2004-01-01 | Deroyal Industries, Inc. | Infused wound care dressings |
| US20070004672A1 (en) * | 2005-07-01 | 2007-01-04 | Dharmendra Jani | Long lasting alginate dry eye, related methods of manufacture and methods of use |
| DE102005060461A1 (de) | 2005-12-17 | 2007-07-12 | Paul Hartmann Ag | Medizinische Zusammensetzung |
| EP2296637B1 (en) * | 2008-04-24 | 2014-04-02 | Medtronic, Inc | Chitosan-containing protective composition |
| EP2288389B1 (en) * | 2008-04-24 | 2014-06-11 | Medtronic, Inc | Cold ionizing radiation sterilization |
| EP2310002B1 (en) * | 2008-04-24 | 2016-11-02 | Medtronic, Inc | Protective gel based on chitosan and oxidized polysaccharide |
| US20090269417A1 (en) * | 2008-04-24 | 2009-10-29 | Medtronic, Inc. | Thiolated chitosan gel |
| US9198997B2 (en) | 2008-04-24 | 2015-12-01 | Medtronic, Inc. | Rehydratable thiolated polysaccharide particles and sponge |
| JP5582711B2 (ja) * | 2008-09-25 | 2014-09-03 | 株式会社エー・アイ・システムプロダクト | ローション状の塗薬 |
| MD4197C1 (ro) * | 2012-10-22 | 2013-09-30 | Мария ДАНУ | Metodă de tratament al ulcerelor trofice |
| US9023399B2 (en) | 2012-11-16 | 2015-05-05 | NU Technology, LLC | Water-soluble anti-inflammatory cream with natural ingredients base |
| US9192574B2 (en) | 2013-10-24 | 2015-11-24 | Medtronic Xomed, Inc. | Chitosan paste wound dressing |
| US9192692B2 (en) | 2013-10-24 | 2015-11-24 | Medtronic Xomed, Inc. | Chitosan stenting paste |
| MX2017004520A (es) | 2014-10-14 | 2018-03-15 | Lynch Samuel | Composiciones para tratar heridas. |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2075837B (en) * | 1980-05-14 | 1984-03-14 | Hisamitsu Pharmaceutical Co | Topical pharmaceutical gel containing anti-inflammatory analgesic agents |
| FR2489145A1 (fr) * | 1980-09-04 | 1982-03-05 | Geistlich Soehne Ag | Compositions pharmaceutiques accelerant la guerison de blessures |
| JPS57142913A (en) * | 1981-02-27 | 1982-09-03 | Nitto Electric Ind Co Ltd | Donor of physiologically active substance |
| JPS58174484A (ja) * | 1982-04-08 | 1983-10-13 | Kao Corp | 感圧性粘着テ−プ又はシ−ト |
| US4604384A (en) * | 1982-06-24 | 1986-08-05 | Smith Robert A | Pharmaceutical gel composition |
| AU558482B2 (en) * | 1982-06-24 | 1987-01-29 | Chiltern Pharmaceuticals Pty. Limited | Pharmaceutical gel composition |
| FR2532546B1 (fr) * | 1982-09-07 | 1985-12-27 | Biotrol Sa Lab | Pate pour la protection de la peau |
| US4643856A (en) * | 1985-03-21 | 1987-02-17 | Moleculon, Inc. | Process of making gelled cellulose triacetate product |
| US4666671A (en) * | 1985-04-03 | 1987-05-19 | Givaudan Corporation | Method for deodorizing urinals and toilet bowls with fragranced gel blocks |
| JPS62123112A (ja) * | 1985-11-22 | 1987-06-04 | Sunstar Inc | 軟膏基剤 |
| GB8818114D0 (en) * | 1988-07-29 | 1988-09-01 | Johnson & Johnson | Haemostatic wound dressing material |
| US5084427A (en) * | 1990-10-22 | 1992-01-28 | Uop | Aqueous suspensions of aluminosilicate molecular sieves |
| US5385729A (en) * | 1991-08-01 | 1995-01-31 | Colgate Palmolive Company | Viscoelastic personal care composition |
| JP3254013B2 (ja) * | 1991-09-10 | 2002-02-04 | ジョンソン・アンド・ジョンソン・メディカル・インコーポレイテッド | 包帯材料およびその製造方法 |
| GB9208731D0 (en) * | 1992-04-22 | 1992-06-10 | Squibb & Sons Inc | Hydrocolloid wound gel |
| US5470576A (en) * | 1992-06-08 | 1995-11-28 | The Kendall Company | Process for preparing the alginate-containing wound dressing |
| US5338541A (en) * | 1992-10-15 | 1994-08-16 | Calgon Corporation | Dual cationic terpolymers providing superior conditioning properties in hair, skin and nail care products |
-
1993
- 1993-03-23 GB GB9306039A patent/GB2276819B/en not_active Expired - Fee Related
-
1994
- 1994-03-15 ZA ZA941827A patent/ZA941827B/xx unknown
- 1994-03-15 IN IN160CA1994 patent/IN177229B/en unknown
- 1994-03-21 AU AU57945/94A patent/AU681618B2/en not_active Ceased
- 1994-03-21 CA CA002119516A patent/CA2119516C/en not_active Expired - Fee Related
- 1994-03-22 EP EP94302020A patent/EP0621031B1/en not_active Expired - Lifetime
- 1994-03-22 AT AT94302020T patent/ATE182072T1/de active
- 1994-03-22 DE DE69419447T patent/DE69419447T2/de not_active Expired - Lifetime
- 1994-03-22 BR BR9401241A patent/BR9401241A/pt not_active Application Discontinuation
- 1994-03-22 ES ES94302020T patent/ES2135541T3/es not_active Expired - Lifetime
- 1994-03-22 JP JP6073796A patent/JP2763492B2/ja not_active Expired - Fee Related
-
1996
- 1996-06-14 US US08/662,103 patent/US5723144A/en not_active Expired - Lifetime
- 1996-08-13 US US08/696,443 patent/US5688522A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU681618B2 (en) | 1997-09-04 |
| GB9306039D0 (en) | 1993-05-12 |
| GB2276819B (en) | 1996-12-11 |
| US5723144A (en) | 1998-03-03 |
| ZA941827B (en) | 1995-09-15 |
| JP2763492B2 (ja) | 1998-06-11 |
| GB2276819A (en) | 1994-10-12 |
| ES2135541T3 (es) | 1999-11-01 |
| IN177229B (enExample) | 1996-12-07 |
| US5688522A (en) | 1997-11-18 |
| EP0621031B1 (en) | 1999-07-14 |
| EP0621031A2 (en) | 1994-10-26 |
| JPH07109220A (ja) | 1995-04-25 |
| ATE182072T1 (de) | 1999-07-15 |
| DE69419447T2 (de) | 2000-01-05 |
| AU5794594A (en) | 1994-09-29 |
| EP0621031A3 (en) | 1995-04-19 |
| BR9401241A (pt) | 1994-11-08 |
| CA2119516A1 (en) | 1994-09-24 |
| DE69419447D1 (de) | 1999-08-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |